Published in Arthritis Rheum on March 01, 2003
Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro. Arthritis Rheum (2011) 1.10
CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network. PLoS One (2011) 1.09
Sphingosine 1-phosphate (S1P) receptor agonists mediate pro-fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad-independent signaling. J Biol Chem (2013) 1.07
Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina. Diabetologia (2007) 1.03
Connective tissue growth factor/CCN2-null mouse embryonic fibroblasts retain intact transforming growth factor-beta responsiveness. Exp Cell Res (2007) 0.99
Pediatric scleroderma: systemic or localized forms. Pediatr Clin North Am (2012) 0.96
Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice. J Histochem Cytochem (2008) 0.95
Effect of protein kinase C delta (PKC-δ) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro. PLoS One (2011) 0.84
PKCδ as a regulator for TGFβ1-induced α-SMA production in a murine nonalcoholic steatohepatitis model. PLoS One (2013) 0.80
The matrix-binding domain of microfibril-associated glycoprotein-1 targets active connective tissue growth factor to a fibroblast-produced extracellular matrix. Macromol Biosci (2010) 0.79
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med (2013) 3.81
The modified sting procedure to correct vesicoureteral reflux: improved results with submucosal implantation within the intramural ureter. J Urol (2004) 2.55
Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease. Am J Respir Crit Care Med (2007) 2.41
Ets proteins in biological control and cancer. J Cell Biochem (2004) 2.24
Blockade of the effects of TGF-beta1 on mesangial cells by overexpression of Smad7. J Am Soc Nephrol (2002) 2.22
Release of biologically active TGF-beta1 by alveolar epithelial cells results in pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2003) 2.14
The HLA-DRB1 shared epitope is associated with susceptibility to rheumatoid arthritis in African Americans through European genetic admixture. Arthritis Rheum (2008) 2.13
Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways. J Biol Chem (2007) 1.73
Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo. Am J Physiol Lung Cell Mol Physiol (2008) 1.68
Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin. Am J Pathol (2003) 1.57
Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts. Arthritis Rheum (2006) 1.57
Fli1 and Ets1 have distinct roles in connective tissue growth factor/CCN2 gene regulation and induction of the profibrotic gene program. J Biol Chem (2006) 1.49
Comparison of the disease activity score using erythrocyte sedimentation rate and C-reactive protein in African Americans with rheumatoid arthritis. J Rheumatol (2013) 1.45
Opposing effects of protein kinase Calpha and protein kinase Cepsilon on collagen expression by human lung fibroblasts are mediated via MEK/ERK and caveolin-1 signaling. J Biol Chem (2005) 1.44
Rotation of the amputated fistula tract for the management of congenital urethral-enteric fistula with severe urethral stenosis: a novel technique with long-term outcomes. J Pediatr Urol (2011) 1.39
Preliminary experience with epsilon aminocaproic acid for treatment of intractable upper tract hematuria in children with hematological disorders. J Urol (2010) 1.39
TGF-beta and CTGF have overlapping and distinct fibrogenic effects on human renal cells. Am J Physiol Renal Physiol (2002) 1.38
Pulmonary and activation-regulated chemokine stimulates collagen production in lung fibroblasts. Am J Respir Cell Mol Biol (2003) 1.38
Endothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy. Am J Pathol (2010) 1.37
Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta. J Biol Chem (2002) 1.35
Most common single-nucleotide polymorphisms associated with rheumatoid arthritis in persons of European ancestry confer risk of rheumatoid arthritis in African Americans. Arthritis Rheum (2010) 1.34
Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in African Americans with early rheumatoid arthritis. Arthritis Rheum (2006) 1.28
Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1. Oncogene (2004) 1.24
Smad1 pathway is activated in systemic sclerosis fibroblasts and is targeted by imatinib mesylate. Arthritis Rheum (2008) 1.20
Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway. J Biol Chem (2004) 1.19
Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylation. J Biol Chem (2007) 1.19
Vitamin D status and its associations with disease activity and severity in African Americans with recent-onset rheumatoid arthritis. J Rheumatol (2009) 1.19
Sphingosine kinase 1 (SPHK1) is induced by transforming growth factor-beta and mediates TIMP-1 up-regulation. J Biol Chem (2004) 1.18
Recent advances in fibroblast signaling and biology in scleroderma. Curr Opin Rheumatol (2004) 1.13
Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta. Arthritis Rheum (2005) 1.12
Microarray analysis of in vitro pericyte differentiation reveals an angiogenic program of gene expression. FASEB J (2004) 1.10
Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts. FASEB J (2005) 1.09
Phosphorylation of Fli1 at threonine 312 by protein kinase C delta promotes its interaction with p300/CREB-binding protein-associated factor and subsequent acetylation in response to transforming growth factor beta. Mol Cell Biol (2009) 1.09
CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling network. PLoS One (2011) 1.09
Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts. J Invest Dermatol (2008) 1.08
Fibrosis in systemic sclerosis. Rheum Dis Clin North Am (2008) 1.08
An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma. Arthritis Rheum (2004) 1.06
Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway. J Biol Chem (2008) 1.06
Reversal of activation of human myofibroblast-like cells by culture on a basement membrane-like substrate. J Hepatol (2002) 1.05
Transcription factor Fli1 regulates collagen fibrillogenesis in mouse skin. Mol Cell Biol (2008) 1.05
Distinct effects of gonadectomy in male and female mice on collagen fibrillogenesis in the skin. J Dermatol Sci (2007) 1.04
Role of p38 MAPK in transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts. J Invest Dermatol (2002) 1.04
Endoglin promotes TGF-β/Smad1 signaling in scleroderma fibroblasts. J Cell Physiol (2011) 1.03
The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis. Curr Opin Rheumatol (2012) 1.03
Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma. Arthritis Rheum (2006) 1.02
Prevalence of osteoporosis and osteopenia among African Americans with early rheumatoid arthritis: the impact of ethnic-specific normative data. J Natl Med Assoc (2005) 1.02
Torsion of an indirect hernia sac within a hydrocele causing acute scrotum: case report and review of the literature. Pediatr Surg Int (2006) 1.02
Sutureless circumcision using 2-octyl cyanoacrylate (Dermabond): appraisal after 18-month experience. Urology (2007) 1.01
Efficacy of nephrectomy for the treatment of nephrogenic hypertension in a pediatric population. J Urol (2003) 0.99
Radiographic severity of rheumatoid arthritis in African Americans: results from a multicenter observational study. Arthritis Care Res (Hoboken) (2010) 0.98
MR imaging of kidneys: functional evaluation using F-15 perfusion imaging. Pediatr Radiol (2003) 0.98
Metabolic risk factors for stone formation in patients with cystic fibrosis. J Urol (2002) 0.97
Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis. Arthritis Res Ther (2012) 0.95
Endoplasmic reticulum stress and endothelial dysfunction. IUBMB Life (2014) 0.94
Helicobacter pylori-induced H,K-ATPase alpha-subunit gene repression is mediated by NF-kappaB p50 homodimer promoter binding. Am J Physiol Gastrointest Liver Physiol (2008) 0.94
Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts. Exp Dermatol (2010) 0.94
Mechanisms of low-density lipoprotein-induced expression of connective tissue growth factor in human aortic endothelial cells. Am J Physiol Heart Circ Physiol (2005) 0.94
Ethnic disparities among patients with pulmonary hypertension associated with systemic sclerosis. J Rheumatol (2007) 0.94
The c-Abl tyrosine kinase controls protein kinase Cδ-induced Fli-1 phosphorylation in human dermal fibroblasts. Arthritis Rheum (2011) 0.93
Modulation of transforming growth factor-beta (TGF-beta) signaling by endogenous sphingolipid mediators. J Biol Chem (2003) 0.93
Lysophosphatidic acid inhibits TGF-beta-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts. Matrix Biol (2004) 0.93
Genetic variant in the promoter of connective tissue growth factor gene confers susceptibility to nephropathy in type 1 diabetes. J Med Genet (2010) 0.92
HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells. J Immunol (2010) 0.92
Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells. Carcinogenesis (2008) 0.91
Detection of connective tissue growth factor (CTGF) in human tear fluid: preliminary results. Acta Ophthalmol Scand (2003) 0.90
Endothelial cells recruit macrophages and contribute to a fibrotic milieu in bleomycin lung injury. Am J Respir Cell Mol Biol (2013) 0.90
Interferon-γ promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) β2. J Cell Physiol (2013) 0.89
Magnetic resonance urography in the evaluation of prenatally diagnosed hydronephrosis and renal dysgenesis. J Urol (2006) 0.88
Platelet derived growth factor induced tenascin-C transcription is phosphoinositide 3-kinase/Akt-dependent and mediated by Ets family transcription factors. J Cell Physiol (2006) 0.88
Connective tissue growth factor in pterygium: simultaneous presence with vascular endothelial growth factor - possible contributing factor to conjunctival scarring. Graefes Arch Clin Exp Ophthalmol (2002) 0.88
Autocrine transforming growth factor β signaling regulates extracellular signal-regulated kinase 1/2 phosphorylation via modulation of protein phosphatase 2A expression in scleroderma fibroblasts. Fibrogenesis Tissue Repair (2010) 0.88
Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism. Arthritis Res Ther (2013) 0.88
A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis. Arthritis Rheum (2010) 0.87
The Role of TGF-β Receptors in Fibrosis. Open Rheumatol J (2012) 0.87
Genetic factors in systemic sclerosis. Arthritis Res Ther (2007) 0.86
The impact of Fli1 deficiency on the pathogenesis of systemic sclerosis. J Dermatol Sci (2010) 0.86
Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Arthritis Rheumatol (2015) 0.85
Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension. Arthritis Rheum (2013) 0.85
Detection of connective tissue growth factor in human aqueous humor. Ophthalmic Res (2002) 0.85
Urological manifestations of Down syndrome. J Urol (2004) 0.85
GATA-6 is a novel transcriptional repressor of the human Tenascin-C gene expression in fibroblasts. Biochim Biophys Acta (2007) 0.85
ALK-5 mediates endogenous and TGF-beta1-induced expression of connective tissue growth factor in embryonic lung. Am J Respir Cell Mol Biol (2006) 0.84
Sulfur mustard induces immune sensitization in hairless guinea pigs. Int Immunopharmacol (2009) 0.84
Caveolin-1 is a negative regulator of MMP-1 gene expression in human dermal fibroblasts via inhibition of Erk1/2/Ets1 signaling pathway. J Dermatol Sci (2011) 0.84
The GMS hypospadias score: assessment of inter-observer reliability and correlation with post-operative complications. J Pediatr Urol (2013) 0.84
Magnetic resonance urography for evaluating outcomes after pediatric pyeloplasty. J Urol (2006) 0.84
Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans. Ann Rheum Dis (2010) 0.84
Upregulation of tenascin-C expression by IL-13 in human dermal fibroblasts via the phosphoinositide 3-kinase/Akt and the protein kinase C signaling pathways. J Invest Dermatol (2006) 0.83
Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis. Arthritis Res Ther (2010) 0.83
Collagen binding alpha2beta1 and alpha1beta1 integrins play contrasting roles in regulation of Ets-1 expression in human liver myofibroblasts. Mol Cell Biochem (2006) 0.83
Renal cell carcinoma in a 2-year-old child with tuberous sclerosis. J Urol (2002) 0.83