Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides.
|
J Exp Med
|
2006
|
13.74
|
2
|
CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor.
|
Immunity
|
2002
|
8.28
|
3
|
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity.
|
Science
|
2011
|
6.19
|
4
|
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation.
|
J Clin Invest
|
2008
|
4.12
|
5
|
PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2.
|
Eur J Immunol
|
2002
|
3.78
|
6
|
The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses.
|
Annu Rev Immunol
|
2001
|
3.41
|
7
|
The IL-21 receptor augments Th2 effector function and alternative macrophage activation.
|
J Clin Invest
|
2006
|
3.33
|
8
|
IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity.
|
Immunity
|
2002
|
3.17
|
9
|
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.
|
J Immunol
|
2004
|
3.15
|
10
|
Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response.
|
J Exp Med
|
2003
|
2.71
|
11
|
IL-21 has a pathogenic role in a lupus-prone mouse model and its blockade with IL-21R.Fc reduces disease progression.
|
J Immunol
|
2007
|
2.71
|
12
|
Abrogation of Ref1 retrovirus restriction in human cells.
|
J Virol
|
2002
|
2.60
|
13
|
Enhanced interleukin (IL)-13 responses in mice lacking IL-13 receptor alpha 2.
|
J Exp Med
|
2003
|
2.54
|
14
|
An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment.
|
J Immunol
|
2007
|
2.46
|
15
|
Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells.
|
J Exp Med
|
2002
|
2.28
|
16
|
Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy.
|
Clin J Oncol Nurs
|
2007
|
2.17
|
17
|
Blockade of the interleukin-21/interleukin-21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis.
|
Arthritis Rheum
|
2007
|
2.10
|
18
|
Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells.
|
J Biol Chem
|
2007
|
2.06
|
19
|
KSHV vFLIP binds to IKK-gamma to activate IKK.
|
J Cell Sci
|
2003
|
2.04
|
20
|
Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses.
|
J Immunol
|
2003
|
1.93
|
21
|
The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.
|
J Immunol
|
2008
|
1.82
|
22
|
Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss.
|
Genomics
|
2003
|
1.81
|
23
|
Th17 cytokines and their emerging roles in inflammation and autoimmunity.
|
Immunol Rev
|
2008
|
1.75
|
24
|
IL-21 induces the apoptosis of resting and activated primary B cells.
|
J Immunol
|
2003
|
1.67
|
25
|
Continuous high-titer HIV-1 vector production.
|
Nat Biotechnol
|
2003
|
1.58
|
26
|
Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease.
|
J Clin Invest
|
2004
|
1.57
|
27
|
IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma.
|
J Immunol
|
2003
|
1.55
|
28
|
Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections.
|
J Immunol
|
2010
|
1.53
|
29
|
PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.
|
J Neuroimmunol
|
2006
|
1.52
|
30
|
Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
|
J Invest Dermatol
|
2011
|
1.51
|
31
|
Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
|
Mol Cell
|
2008
|
1.46
|
32
|
HIV-1 lentiviral vector immunogenicity is mediated by Toll-like receptor 3 (TLR3) and TLR7.
|
J Virol
|
2010
|
1.44
|
33
|
IL-22 induces an acute-phase response.
|
J Immunol
|
2010
|
1.40
|
34
|
Use of an objective tool to assess platelet inhibition prior to off-pump coronary surgery to reduce blood usage.
|
J Invasive Cardiol
|
2012
|
1.40
|
35
|
Nurse case management improves blood pressure, emotional distress and diabetes complication screening.
|
Diabetes Res Clin Pract
|
2005
|
1.30
|
36
|
PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells.
|
EMBO Mol Med
|
2011
|
1.27
|
37
|
Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigen.
|
J Immunol
|
2005
|
1.26
|
38
|
A phagocytic cell line markedly improves survival of infected neutropenic mice.
|
J Leukoc Biol
|
2005
|
1.23
|
39
|
IL-21R is essential for epicutaneous sensitization and allergic skin inflammation in humans and mice.
|
J Clin Invest
|
2008
|
1.17
|
40
|
Pilot evaluation of citalopram for the treatment of hot flashes in women with inadequate benefit from venlafaxine.
|
J Palliat Med
|
2005
|
1.17
|
41
|
Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts.
|
J Leukoc Biol
|
2006
|
1.11
|
42
|
Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene.
|
FEMS Microbiol Lett
|
2004
|
1.11
|
43
|
Tumor necrosis factor alpha blockade exacerbates murine psoriasis-like disease by enhancing Th17 function and decreasing expansion of Treg cells.
|
Arthritis Rheum
|
2010
|
1.10
|
44
|
Selective ERK activation differentiates mouse and human tolerogenic dendritic cells, expands antigen-specific regulatory T cells, and suppresses experimental inflammatory arthritis.
|
Arthritis Rheum
|
2011
|
1.08
|
45
|
IL-21 receptor is critical for the development of memory B cell responses.
|
J Immunol
|
2010
|
1.05
|
46
|
Murine leukemia virus particle assembly quantitated by fluorescence microscopy: role of Gag-Gag interactions and membrane association.
|
J Virol
|
2003
|
1.05
|
47
|
BTLA: a new inhibitory receptor with a B7-like ligand.
|
Trends Immunol
|
2003
|
1.04
|
48
|
Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A.
|
J Immunol
|
2002
|
1.04
|
49
|
Selective functional inhibition of JAK-3 is sufficient for efficacy in collagen-induced arthritis in mice.
|
Arthritis Rheum
|
2010
|
1.03
|
50
|
IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J mice.
|
J Immunol
|
2012
|
1.02
|
51
|
IL-21 receptor expression determines the temporal phases of experimental autoimmune encephalomyelitis.
|
Exp Neurol
|
2007
|
0.98
|
52
|
Autoreactive T cells mediate NK cell degeneration in autoimmune disease.
|
J Immunol
|
2006
|
0.97
|
53
|
IL-22R, IL-10R2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22.
|
J Mol Biol
|
2008
|
0.97
|
54
|
A strabismus susceptibility locus on chromosome 7p.
|
Proc Natl Acad Sci U S A
|
2003
|
0.97
|
55
|
DNA vaccines encoding retrovirus-based virus-like particles induce efficient immune responses without adjuvant.
|
Vaccine
|
2005
|
0.97
|
56
|
Effect of the internal promoter on insertional gene activation by lentiviral vectors with an intact HIV long terminal repeat.
|
J Virol
|
2010
|
0.95
|
57
|
B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model.
|
Blood
|
2005
|
0.95
|
58
|
The β-globin locus control region in combination with the EF1α short promoter allows enhanced lentiviral vector-mediated erythroid gene expression with conserved multilineage activity.
|
Mol Ther
|
2012
|
0.93
|
59
|
Enhanced GITR/GITRL interactions augment IL-27 expression and induce IL-10-producing Tr-1 like cells.
|
Eur J Immunol
|
2012
|
0.92
|
60
|
IL-21 effects on human IgE production in response to IL-4 or IL-13.
|
Cell Immunol
|
2005
|
0.90
|
61
|
Growth factors improve gene expression after lentiviral transduction in human adult and fetal hepatocytes.
|
J Gene Med
|
2007
|
0.90
|
62
|
Gene transfer to repopulating human CD34+ cells using amphotropic-, GALV-, or RD114-pseudotyped HIV-1-based vectors from stable producer cells.
|
Mol Ther
|
2005
|
0.89
|
63
|
Therapeutic opportunities in the B7/CD28 family of ligands and receptors.
|
Curr Opin Pharmacol
|
2005
|
0.88
|
64
|
Insertional mutagenesis by retroviral vectors: current concepts and methods of analysis.
|
Curr Gene Ther
|
2013
|
0.87
|
65
|
Kaposi's sarcoma-associated herpesvirus vFLIP and human T cell lymphotropic virus type 1 Tax oncogenic proteins activate IkappaB kinase subunit gamma by different mechanisms independent of the physiological cytokine-induced pathways.
|
J Virol
|
2011
|
0.86
|
66
|
Safer, silencing-resistant lentiviral vectors: optimization of the ubiquitous chromatin-opening element through elimination of aberrant splicing.
|
J Virol
|
2012
|
0.86
|
67
|
A FLIPR-based assay to assess potency and selectivity of inhibitors of the TEC family kinases Btk and Itk.
|
Assay Drug Dev Technol
|
2007
|
0.84
|
68
|
Tumor cells secreting IL-13 but not IL-13Ralpha2 fusion protein have reduced tumorigenicity in vivo.
|
Int Immunol
|
2004
|
0.83
|
69
|
Conjugation of lentivirus to paramagnetic particles via nonviral proteins allows efficient concentration and infection of primary acute myeloid leukemia cells.
|
J Virol
|
2005
|
0.82
|
70
|
Lentiviral vector expression of tumour antigens in dendritic cells as an immunotherapeutic strategy.
|
Cancer Immunol Immunother
|
2005
|
0.82
|
71
|
Comparable in vivo efficacy of CD28/B7, ICOS/GL50, and ICOS/GL50B costimulatory pathways in murine tumor models: IFNgamma-dependent enhancement of CTL priming, effector functions, and tumor specific memory CTL.
|
Cell Immunol
|
2003
|
0.81
|
72
|
Cell-surface and cytokine biomarkers in autoimmune and inflammatory diseases.
|
Drug Discov Today
|
2006
|
0.81
|
73
|
DNA fusion vaccine designs to induce tumor-lytic CD8+ T-cell attack via the immunodominant cysteine-containing epitope of NY-ESO 1.
|
Int J Cancer
|
2013
|
0.81
|
74
|
Unexpected targets and triggers of autoimmunity.
|
J Clin Immunol
|
2014
|
0.80
|
75
|
The pathology and immunology of atopic dermatitis.
|
Inflamm Allergy Drug Targets
|
2011
|
0.80
|
76
|
Targeting lentiviral vectors for cancer immunotherapy.
|
Curr Cancer Ther Rev
|
2011
|
0.80
|
77
|
Dehydroepiandrosterone for the treatment of hot flashes: a pilot study.
|
Support Cancer Ther
|
2006
|
0.80
|
78
|
Pilot evaluation of aprepitant for the treatment of hot flashes.
|
Support Cancer Ther
|
2006
|
0.78
|
79
|
The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice.
|
Cell Immunol
|
2010
|
0.78
|
80
|
Cytosolic phospholipase A2α blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs.
|
J Immunol
|
2011
|
0.77
|
81
|
Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys.
|
Rheumatology (Oxford)
|
2011
|
0.75
|
82
|
Geriatric trauma G-60 falls with hip fractures: A pilot study of acute pain management using femoral nerve fascia iliac blocks.
|
J Trauma Acute Care Surg
|
2015
|
0.75
|