Published in J Am Chem Soc on March 26, 2003
Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. J Am Chem Soc (2011) 1.25
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res (2010) 1.19
DNA-multichromophore systems. Chem Rev (2012) 1.10
Labeling DNA for single-molecule experiments: methods of labeling internal specific sequences on double-stranded DNA. Nanoscale (2011) 1.00
Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase. Nucleic Acids Res (2005) 0.93
Conversion of DNA methyltransferases into azidonucleosidyl transferases via synthetic cofactors. Nucleic Acids Res (2005) 0.85
Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs. Org Biomol Chem (2013) 0.81
Synthesis of S-Adenosyl-L-Methionine Analogs with Extended Transferable Groups for Methyltransferase-Directed Labeling of DNA and RNA. Curr Protoc Nucleic Acid Chem (2016) 0.77
Sequence-specific labeling of nucleic acids and proteins with methyltransferases and cofactor analogues. J Vis Exp (2014) 0.77
Chemoenzymatic synthesis and utilization of a SAM analog with an isomorphic nucleobase. Org Biomol Chem (2016) 0.76
AdoMet analog synthesis and utilization: current state of the art. Curr Opin Biotechnol (2016) 0.76
Methyltransferase-directed covalent coupling of fluorophores to DNA. Chem Sci (2017) 0.75
Methyltransferase directed labeling of biomolecules and its applications. Angew Chem Int Ed Engl (2016) 0.75
Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases. Nat Chem Biol (2005) 1.56
Enzymatic site-specific functionalization of protein methyltransferase substrates with alkynes for click labeling. Angew Chem Int Ed Engl (2010) 1.37
A new tool for biotechnology: AdoMet-dependent methyltransferases. Trends Biotechnol (2007) 1.35
Targeted labeling of DNA by methyltransferase-directed transfer of activated groups (mTAG). J Am Chem Soc (2007) 1.25
Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases. Nat Protoc (2006) 1.22
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res (2010) 1.19
A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases. Chembiochem (2012) 1.07
2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence. J Am Chem Soc (2007) 1.06
Sequence-specific methyltransferase-induced labeling of DNA (SMILing DNA). Chembiochem (2004) 1.05
DNA mismatch-specific base flipping by a bisacridine macrocycle. Chembiochem (2003) 0.98
Enzymatically incorporated genomic tags for optical mapping of DNA-binding proteins. Angew Chem Int Ed Engl (2012) 0.95
Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases. Nucleic Acids Res (2012) 0.93
Polycyclic aromatic DNA-base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angew Chem Int Ed Engl (2003) 0.92
The stability of pseudopeptides bearing sulfoximines as chiral backbone modifying element towards proteinase K. Bioorg Med Chem Lett (2003) 0.90
Enzyme-directed positioning of nanoparticles on large DNA templates. Bioconjug Chem (2007) 0.89
Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry (CCMS). J Vis Exp (2010) 0.89
Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule. Bioconjug Chem (2010) 0.88
Selective recognition of pyrimidine-pyrimidine DNA mismatches by distance-constrained macrocyclic bis-intercalators. Nucleic Acids Res (2008) 0.88
Synthesis of S-adenosyl-L-homocysteine capture compounds for selective photoinduced isolation of methyltransferases. Chembiochem (2010) 0.88
Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation. Int J Cancer (2008) 0.87
Quantitative labeling of long plasmid DNA with nanometer precision. Chembiochem (2007) 0.86
Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2. J Control Release (2007) 0.86
Sequence-specific Methyltransferase-Induced Labelling (SMILing) of plasmid DNA for studying cell transfection. Bioorg Med Chem (2007) 0.85
Sequence-specific covalent labelling of DNA. Biochem Soc Trans (2011) 0.82
Functional reassembly of split enzymes on-site: a novel approach for highly sequence-specific targeted DNA methylation. Chembiochem (2008) 0.82
Rapid parallel mutation scanning of gene fragments using a microelectronic protein-DNA chip format. Nucleic Acids Res (2002) 0.81
Molecular scale architecture: engineered three- and four-way junctions. Bioconjug Chem (2007) 0.81
Toward single-molecule optical mapping of the epigenome. ACS Nano (2013) 0.81
Sequence-specific DNA labeling using methyltransferases. Methods Mol Biol (2004) 0.81
6-Thioguanine in DNA as CD-spectroscopic probe to study local structural changes upon protein binding. Chirality (2008) 0.80
Convenient synthesis of oligodeoxynucleotides containing 2'-deoxy-6-thioinosine. Nucleosides Nucleotides Nucleic Acids (2003) 0.75
Recognition of homopyrimidine mismatches by distance-constrained macrocyclic bisintercalators. Nucleic Acids Symp Ser (Oxf) (2008) 0.75
DNA labelling topologies for monitoring DNA-protein complex formation by fluorescence anisotropy. Nucleosides Nucleotides Nucleic Acids (2007) 0.75
Profiling of methyltransferases and other S-Adenosyl-L-homocysteine-binding proteins by Capture Compound mass spectrometry. Methods Mol Biol (2012) 0.75