Published in Angew Chem Int Ed Engl on July 12, 2010
Current chemical biology approaches to interrogate protein methyltransferases. ACS Chem Biol (2012) 1.70
Chemical reporters for biological discovery. Nat Chem Biol (2013) 1.69
Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. ACS Chem Biol (2011) 1.38
Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. J Am Chem Soc (2011) 1.25
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res (2010) 1.19
A chemical method for labeling lysine methyltransferase substrates. Chembiochem (2010) 1.18
An unexpected journey: lysine methylation across the proteome. Biochim Biophys Acta (2014) 1.11
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. J Am Chem Soc (2012) 1.09
Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. J Am Chem Soc (2012) 1.02
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. Mol Biosyst (2011) 0.96
Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. Org Lett (2013) 0.95
Super-resolution optical DNA Mapping via DNA methyltransferase-directed click chemistry. Nucleic Acids Res (2014) 0.93
Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases. Nucleic Acids Res (2012) 0.93
Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proc Natl Acad Sci U S A (2013) 0.92
Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers (2014) 0.88
Profiling protein methylation with cofactor analog containing terminal alkyne functionality. Curr Protoc Chem Biol (2013) 0.84
A journey toward Bioorthogonal Profiling of Protein Methylation inside living cells. Curr Opin Chem Biol (2013) 0.84
Structural characterization of the mitomycin 7-O-methyltransferase. Proteins (2011) 0.82
Chemoenzymatic synthesis and in situ application of S-adenosyl-L-methionine analogs. Org Biomol Chem (2013) 0.81
Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferases. Org Lett (2014) 0.81
Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification. Nucleic Acids Res (2015) 0.80
Specific and quantitative labeling of biomolecules using click chemistry. Front Physiol (2014) 0.80
Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. ACS Chem Biol (2013) 0.80
A sensitive mass spectrum assay to characterize engineered methionine adenosyltransferases with S-alkyl methionine analogues as substrates. Anal Biochem (2013) 0.78
Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine. Curr Protoc Chem Biol (2013) 0.78
Chemical methods for the proteome-wide identification of posttranslationally modified proteins. Curr Opin Chem Biol (2014) 0.78
Sequence-specific labeling of nucleic acids and proteins with methyltransferases and cofactor analogues. J Vis Exp (2014) 0.77
Expanding applications of chemical genetics in signal transduction. Cell Cycle (2012) 0.76
AdoMet analog synthesis and utilization: current state of the art. Curr Opin Biotechnol (2016) 0.76
Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS Chem Biol (2016) 0.76
Chemical Methods for Encoding and Decoding of Posttranslational Modifications. Cell Chem Biol (2016) 0.75
Quantum Chemical Calculations and Experimental Validation of the Photoclick Reaction for Fluorescent Labeling of the 5' cap of Eukaryotic mRNAs. ChemistryOpen (2015) 0.75
Methyltransferase directed labeling of biomolecules and its applications. Angew Chem Int Ed Engl (2016) 0.75
The winding path of protein methylation research: milestones and new frontiers. Nat Rev Mol Cell Biol (2017) 0.75
Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive. Nature (2007) 3.68
Toward a unified nomenclature for mammalian ADP-ribosyltransferases. Trends Biochem Sci (2010) 3.32
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell (2009) 2.50
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation. Mol Cell (2008) 2.29
Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP. EMBO Rep (2003) 2.21
The gamma 2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses. Mol Cell Neurosci (2003) 2.18
The gamma2 subunit of GABA(A) receptors is a substrate for palmitoylation by GODZ. J Neurosci (2004) 2.07
Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta (2007) 2.07
The ins and outs of MYC regulation by posttranslational mechanisms. J Biol Chem (2006) 1.96
The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop. Proc Natl Acad Sci U S A (2011) 1.90
Controlled exposure of healthy young volunteers to ozone causes cardiovascular effects. Circulation (2012) 1.85
A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood (2011) 1.84
The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering. J Neurosci (2004) 1.75
GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. J Neurosci (2006) 1.68
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol (2008) 1.63
SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310. J Cell Sci (2010) 1.60
Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases. Nat Chem Biol (2005) 1.56
Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases. Nat Struct Mol Biol (2013) 1.47
GABAergic control of adult hippocampal neurogenesis in relation to behavior indicative of trait anxiety and depression states. J Neurosci (2007) 1.41
Order or chaos? An evaluation of the regulation of protein kinase CK2. Biochem Cell Biol (2004) 1.41
SH3TC2/KIAA1985 protein is required for proper myelination and the integrity of the node of Ranvier in the peripheral nervous system. Proc Natl Acad Sci U S A (2009) 1.39
Distinct gamma2 subunit domains mediate clustering and synaptic function of postsynaptic GABAA receptors and gephyrin. J Neurosci (2005) 1.36
Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation. Proc Natl Acad Sci U S A (2009) 1.36
A new tool for biotechnology: AdoMet-dependent methyltransferases. Trends Biotechnol (2007) 1.35
A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation. Hum Mutat (2009) 1.32
PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene (2005) 1.30
CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation. Circulation (2006) 1.27
Signaling by IL-31 and functional consequences. Eur J Cell Biol (2011) 1.25
Targeted labeling of DNA by methyltransferase-directed transfer of activated groups (mTAG). J Am Chem Soc (2007) 1.25
Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases. Nat Protoc (2006) 1.22
The multiple personalities of the regulatory subunit of protein kinase CK2: CK2 dependent and CK2 independent roles reveal a secret identity for CK2beta. Int J Biol Sci (2005) 1.21
Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling. Nucleic Acids Res (2010) 1.19
The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton. Cell Signal (2005) 1.19
The pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping protein. Mol Cell Biol (2005) 1.18
Regulation of the transcription factor FOXM1c by Cyclin E/CDK2. FEBS Lett (2006) 1.16
The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2. J Biol Chem (2002) 1.15
A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions. Mol Cell Biol (2005) 1.15
Dual modes of interaction between XRCC4 and polynucleotide kinase/phosphatase: implications for nonhomologous end joining. J Biol Chem (2010) 1.14
Neurotransmitter modulation of small-conductance Ca2+-activated K+ channels by regulation of Ca2+ gating. Neuron (2008) 1.11
GABAergic terminals are required for postsynaptic clustering of dystrophin but not of GABA(A) receptors and gephyrin. J Neurosci (2002) 1.10
The protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation site. BMC Biochem (2006) 1.10
The human trithorax protein hASH2 functions as an oncoprotein. Cancer Res (2008) 1.08
A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems. Am J Hum Genet (2009) 1.08
ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation. Cell Commun Signal (2013) 1.08
The transcription factor Yin Yang 1 is an activator of BACE1 expression. J Neurochem (2006) 1.08
A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases. Chembiochem (2012) 1.07
2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence. J Am Chem Soc (2007) 1.06
SH3TC2, a protein mutant in Charcot-Marie-Tooth neuropathy, links peripheral nerve myelination to endosomal recycling. Brain (2010) 1.06
Sequence-specific methyltransferase-induced labeling of DNA (SMILing DNA). Chembiochem (2004) 1.05
An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets. Mol Cell Proteomics (2008) 1.04
The role of CKIP-1 in cell morphology depends on its interaction with actin-capping protein. J Biol Chem (2006) 1.04
Regulation of cell proliferation and survival: convergence of protein kinases and caspases. Biochim Biophys Acta (2009) 1.02
Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation. Nat Rev Mol Cell Biol (2013) 1.02
IL-31 regulates differentiation and filaggrin expression in human organotypic skin models. J Allergy Clin Immunol (2011) 1.02
Regulation of NF-κB signalling by the mono-ADP-ribosyltransferase ARTD10. Nat Commun (2013) 1.01
Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions. J Biol Chem (2002) 1.01
Design of a new fluorescent cofactor for DNA methyltransferases and sequence-specific labeling of DNA. J Am Chem Soc (2003) 1.01
Casein kinase 2 beta-subunit is a regulator of bone morphogenetic protein 2 signaling. Biophys J (2010) 0.99
Learning how to read ADP-ribosylation. Cell (2009) 0.99
Phosphorylation regulates the stability of the regulatory CK2beta subunit. Oncogene (2002) 0.99
Protein kinase CK2 catalyzes tyrosine phosphorylation in mammalian cells. Cell Signal (2008) 0.99
The Pleckstrin homology domain of CK2 interacting protein-1 is required for interactions and recruitment of protein kinase CK2 to the plasma membrane. J Biol Chem (2004) 0.98
A peptide-based target screen implicates the protein kinase CK2 in the global regulation of caspase signaling. Sci Signal (2011) 0.98
DNA mismatch-specific base flipping by a bisacridine macrocycle. Chembiochem (2003) 0.98
Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains. Structure (2013) 0.97
Cytokines and the skin barrier. Int J Mol Sci (2013) 0.96
Enzymatically incorporated genomic tags for optical mapping of DNA-binding proteins. Angew Chem Int Ed Engl (2012) 0.95
Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity. Biochem J (2003) 0.95
Nuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17. J Biol Chem (2006) 0.94
YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription. Biochem Biophys Res Commun (2004) 0.94
Loss of pannexin 1 attenuates melanoma progression by reversion to a melanocytic phenotype. J Biol Chem (2012) 0.94
Programmable sequence-specific click-labeling of RNA using archaeal box C/D RNP methyltransferases. Nucleic Acids Res (2012) 0.93
Caspase-dependent regulation and subcellular redistribution of the transcriptional modulator YY1 during apoptosis. Mol Cell Biol (2005) 0.92
Evidence for regulation of mitotic progression through temporal phosphorylation and dephosphorylation of CK2alpha. Mol Cell Biol (2009) 0.92
Polycyclic aromatic DNA-base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase. Angew Chem Int Ed Engl (2003) 0.92
CK2 interacting proteins: emerging paradigms for CK2 regulation? Mol Cell Biochem (2005) 0.92
Regulation of sirtuin function by posttranslational modifications. Front Pharmacol (2012) 0.91
Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62. Cell Commun Signal (2012) 0.91
The stability of pseudopeptides bearing sulfoximines as chiral backbone modifying element towards proteinase K. Bioorg Med Chem Lett (2003) 0.90
Protein kinase CK2 is a constitutively active enzyme that promotes cell survival: strategies to identify CK2 substrates and manipulate its activity in mammalian cells. Methods Enzymol (2010) 0.90
Expanding functions of intracellular resident mono-ADP-ribosylation in cell physiology. FEBS J (2013) 0.90
The transcription factor YY1 is a substrate for Polo-like kinase 1 at the G2/M transition of the cell cycle. PLoS One (2011) 0.90
H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1. Hum Pathol (2009) 0.90
A novel costimulatory signaling in human T lymphocytes by a splice variant of CD28. Blood (2002) 0.89
Profiling of methyltransferases and other S-adenosyl-L-homocysteine-binding Proteins by Capture Compound Mass Spectrometry (CCMS). J Vis Exp (2010) 0.89
Enzyme-directed positioning of nanoparticles on large DNA templates. Bioconjug Chem (2007) 0.89
Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors. Eur J Pharm Sci (2013) 0.89
Progress in the function and regulation of ADP-Ribosylation. Sci Signal (2011) 0.89
Repression of in vivo growth of Myc/Ras transformed tumor cells by Mad1. Oncogene (2002) 0.88
Targeted DNA methylation by a DNA methyltransferase coupled to a triple helix forming oligonucleotide to down-regulate the epithelial cell adhesion molecule. Bioconjug Chem (2010) 0.88