IL-10, an inflammatory/inhibitory cytokine, but not always.

PubWeight™: 1.76‹?› | Rank: Top 3%

🔗 View Article (PMID 12644313)

Published in Immunol Lett on April 03, 2003

Authors

Pio Conti1, Duraisamy Kempuraj, Kristiana Kandere, Mario Di Gioacchino, Renato C Barbacane, Maria L Castellani, Mario Felaco, William Boucher, Richard Letourneau, Theoharis C Theoharides

Author Affiliations

1: Immunology Division, University of Chieti, School of Medicine, Chieti, Italy. pconti@unich.it

Articles citing this

Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Infect Immun (2004) 2.84

Microbial manipulation of receptor crosstalk in innate immunity. Nat Rev Immunol (2011) 2.01

Mast cells and inflammation. Biochim Biophys Acta (2010) 1.91

CD28 down-regulation on circulating CD4 T-cells is associated with poor prognoses of patients with idiopathic pulmonary fibrosis. PLoS One (2010) 1.53

Longitudinal modulation of immune system cytokine profile during pregnancy. Cytokine (2010) 1.26

Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production. Hum Genet (2008) 1.19

Innate immunity and its regulation by mast cells. J Immunol (2013) 1.19

Opsonic requirements for dendritic cell-mediated responses to Cryptococcus neoformans. Infect Immun (2005) 1.17

Bilateral changes of TNF-alpha and IL-10 protein in the lumbar and cervical dorsal root ganglia following a unilateral chronic constriction injury of the sciatic nerve. J Neuroinflammation (2010) 1.14

Serum cytokines associated with severity and complications of kala-azar. Pathog Glob Health (2013) 1.03

Nonresolving inflammation in gp91phox-/- mice, a model of human chronic granulomatous disease, has lower adenosine and cyclic adenosine 5'-monophosphate. J Immunol (2009) 1.03

Cytokine expression pattern in the genital tract of Chlamydia trachomatis positive infertile women - implication for T-cell responses. Clin Exp Immunol (2004) 1.01

CD28 down-regulation on CD4 T cells is a marker for graft dysfunction in lung transplant recipients. Am J Respir Crit Care Med (2008) 0.93

Role of cervical dendritic cell subsets, co-stimulatory molecules, cytokine secretion profile and beta-estradiol in development of sequalae to Chlamydia trachomatis infection. Reprod Biol Endocrinol (2008) 0.91

Does immune activation continue during an attack-free period in familial Mediterranean fever? Clin Exp Immunol (2004) 0.91

IL-10 induction by Bordetella parapertussis limits a protective IFN-gamma response. J Immunol (2009) 0.89

In infertile women, cells from Chlamydia trachomatis infected sites release higher levels of interferon-gamma, interleukin-10 and tumor necrosis factor-alpha upon heat-shock-protein stimulation than fertile women. Reprod Biol Endocrinol (2008) 0.89

Understanding and Managing Pregnancy in Patients with Lupus. Autoimmune Dis (2015) 0.89

T follicular helper cells, T follicular regulatory cells and autoimmunity. Int Immunol (2015) 0.87

Host immune responses to chlamydial inclusion membrane proteins B and C in Chlamydia trachomatis infected women with or without fertility disorders. Reprod Biol Endocrinol (2009) 0.85

Interleukin-10 in murine metal-induced systemic autoimmunity. Clin Exp Immunol (2005) 0.84

Antibody array-generated profiles of cytokine release from THP-1 leukemic monocytes exposed to different amphotericin B formulations. Antimicrob Agents Chemother (2004) 0.84

Comparison of Two Commercial Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Modified Live Vaccines against Heterologous Type 1 and Type 2 PRRSV Challenge in Growing Pigs. Clin Vaccine Immunol (2015) 0.83

Interleukin 10 and tumor necrosis factor-alpha in pregnancy: aspects of interest in clinical obstetrics. ISRN Obstet Gynecol (2012) 0.81

Expression levels of novel cytokine IL-32 in periodontitis and its role in the suppression of IL-8 production by human gingival fibroblasts stimulated with Porphyromonas gingivalis. J Oral Microbiol (2012) 0.81

IL-10-induced gp130 expression in mouse mast cells permits IL-6 trans-signaling. J Leukoc Biol (2011) 0.81

Stress triggers coronary mast cells leading to cardiac events. Ann Allergy Asthma Immunol (2013) 0.80

Analysis of lymphocytes in patients with Plasmodium vivax malaria and its relation to the annexin-A1 and IL-10. Malar J (2013) 0.80

Modulation of cytokines and transcription factors (T-Bet and GATA3) in CD4 enriched cervical cells of Chlamydia trachomatis infected fertile and infertile women upon stimulation with chlamydial inclusion membrane proteins B and C. Reprod Biol Endocrinol (2009) 0.79

Cytokine profile in Nigerians with tubal infertility. Cent Eur J Immunol (2016) 0.79

Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection. PLoS Pathog (2016) 0.78

Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation. J Inflamm (Lond) (2010) 0.78

Induction of STAT1 phosphorylation at serine 727 and expression of proinflammatory cytokines by porcine reproductive and respiratory syndrome virus. PLoS One (2013) 0.78

Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis. PLoS One (2016) 0.77

Dendritic cells from chronic lymphocytic leukemia patients are normal regardless of Ig V gene mutation status. Mol Med (2006) 0.76

Enhancement of anti-murine colon cancer immunity by fusion of a SARS fragment to a low-immunogenic carcinoembryonic antigen. Biol Proced Online (2012) 0.76

Anti-ribosomal phosphoprotein autoantibody triggers interleukin-10 overproduction via phosphatidylinositol 3-kinase-dependent signalling pathways in lipopolysaccharide-activated macrophages. Immunology (2009) 0.76

Pneumocystis infection enhances antibody-mediated resistance to a subsequent influenza infection. J Immunol (2008) 0.76

Comparison of 2 commercial single-dose Mycoplasma hyopneumoniae vaccines and porcine reproductive and respiratory syndrome virus (PRRSV) vaccines on pigs dually infected with M. hyopneumoniae and PRRSV. Can J Vet Res (2016) 0.75

A functional polymorphism in the promoter region of interleukin-10 gene increases the risk for spontaneous abortions--a triad study. J Assist Reprod Genet (2015) 0.75

Effects of grape seed extract on periodontal disease: an experimental study in rats. J Appl Oral Sci (2017) 0.75

Estriol modulates the functional activity of phagocytes and NK cells. Dokl Biol Sci (2008) 0.75

Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels. Int J Inflam (2017) 0.75

Association between TNF, IL1B, IL6, IL10 and IFNG polymorphisms and recurrent miscarriage: a case control study. Reprod Biol Endocrinol (2017) 0.75

Articles by these authors

Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08

Mast Cells, Mastocytosis, and Related Disorders. N Engl J Med (2015) 3.90

Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine. Mayo Clin Proc (2002) 2.67

Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. J Clin Oncol (2006) 2.51

Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol Rev (2007) 1.94

Key role of CRF in the skin stress response system. Endocr Rev (2013) 1.77

Neuroimmunology of stress: skin takes center stage. J Invest Dermatol (2006) 1.72

The mast cell in interstitial cystitis: role in pathophysiology and pathogenesis. Urology (2007) 1.67

Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts. Cardiovasc Res (2005) 1.64

Neuroimmunoendocrine circuitry of the 'brain-skin connection'. Trends Immunol (2005) 1.58

Quantitative assessment of the compliance with once-daily sublingual immunotherapy in children (EASY project: evaluation of a novel SLIT formulation during a year). Pediatr Allergy Immunol (2007) 1.57

IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin. Proc Natl Acad Sci U S A (2010) 1.56

High levels of intrauterine corticotropin-releasing hormone, urocortin, tryptase, and interleukin-8 in spontaneous abortions. Endocrinology (2003) 1.52

Mast cells as targets of corticotropin-releasing factor and related peptides. Trends Pharmacol Sci (2004) 1.50

Impact of stress and mast cells on brain metastases. J Neuroimmunol (2008) 1.46

Corticotropin-releasing hormone-receptor 2 is required for acute stress-induced bladder vascular permeability and release of vascular endothelial growth factor. BJU Int (2010) 1.46

Flavonols inhibit proinflammatory mediator release, intracellular calcium ion levels and protein kinase C theta phosphorylation in human mast cells. Br J Pharmacol (2005) 1.45

Acute stress induces cardiac mast cell activation and histamine release, effects that are increased in Apolipoprotein E knockout mice. Cardiovasc Res (2002) 1.45

Acute stress-induced seizures and loss of consciousness in a ten-year-old boy with cutaneous mastocytosis. J Clin Psychopharmacol (2002) 1.45

Chronic fatigue syndrome, mast cells, and tricyclic antidepressants. J Clin Psychopharmacol (2005) 1.44

Human mast cells express corticotropin-releasing hormone (CRH) receptors and CRH leads to selective secretion of vascular endothelial growth factor. J Immunol (2005) 1.31

Corticotropin-releasing hormone and brain mast cells regulate blood-brain-barrier permeability induced by acute stress. J Pharmacol Exp Ther (2002) 1.23

Corticotropin-releasing hormone and its structurally related urocortin are synthesized and secreted by human mast cells. Endocrinology (2003) 1.14

Brain cytokines and neuropsychiatric disorders. J Clin Psychopharmacol (2004) 1.14

Proinflammatory cytokines in sera of elderly patients with dementia: levels in vascular injury are higher than those of mild-moderate Alzheimer's disease patients. Exp Gerontol (2002) 1.12

IL-1 induces vesicular secretion of IL-6 without degranulation from human mast cells. J Immunol (2003) 1.11

Corticotropin-releasing hormone induces skin vascular permeability through a neurotensin-dependent process. Proc Natl Acad Sci U S A (2006) 1.10

Serotonin-selective reuptake inhibitors and nonsteroidal anti-inflammatory drugs--important considerations of adverse interactions especially for the treatment of myalgic encephalomyelitis/chronic fatigue syndrome. J Clin Psychopharmacol (2011) 1.09

Spectrum of mast cell activation disorders. Expert Rev Clin Immunol (2014) 1.08

Advances in therapy with antileukotriene drugs. Ann Clin Lab Sci (2004) 1.07

Mast cell tryptase: a new biomarker in patients with stable coronary artery disease. Atherosclerosis (2005) 1.05

Mitochondrial DNA and anti-mitochondrial antibodies in serum of autistic children. J Neuroinflammation (2010) 1.04

Substance P (SP) induces expression of functional corticotropin-releasing hormone receptor-1 (CRHR-1) in human mast cells. J Invest Dermatol (2011) 1.03

Human mast cell degranulation and preformed TNF secretion require mitochondrial translocation to exocytosis sites: relevance to atopic dermatitis. J Allergy Clin Immunol (2011) 1.02

Antiinflammatory effects in THP-1 cells treated with verbascoside. Phytother Res (2010) 1.02

Dysregulation of chemo-cytokine production in schizophrenic patients versus healthy controls. BMC Neurosci (2011) 1.01

Role of mast cells in tumor growth. Ann Clin Lab Sci (2007) 1.01

Neurotensin is increased in serum of young children with autistic disorder. J Neuroinflammation (2010) 1.01

Quantitative assessment of the compliance with a once-daily sublingual immunotherapy regimen in real life (EASY Project: Evaluation of A novel SLIT formulation during a Year). J Allergy Clin Immunol (2006) 0.96

Mast cells in allergic and inflammatory diseases. Curr Pharm Des (2012) 0.95

Autism: an emerging 'neuroimmune disorder' in search of therapy. Expert Opin Pharmacother (2009) 0.95

Effect of stress on brain inflammation and multiple sclerosis. Autoimmun Rev (2013) 0.95

Mercury induces inflammatory mediator release from human mast cells. J Neuroinflammation (2010) 0.94

Corticotropin-releasing hormone induces vascular endothelial growth factor release from human mast cells via the cAMP/protein kinase A/p38 mitogen-activated protein kinase pathway. Mol Pharmacol (2005) 0.94

Perinatal stress, brain inflammation and risk of autism-review and proposal. BMC Pediatr (2012) 0.94

Inducible nitric oxide synthase and heme oxygenase-1 in rat heart: direct effect of chronic exposure to hypoxia. Ann Clin Lab Sci (2003) 0.93

Activity of matrix metallo proteinases (MMPs) and the tissue inhibitor of MMP (TIMP)-1 in electromagnetic field-exposed THP-1 cells. J Cell Physiol (2012) 0.92

Skin corticotropin-releasing hormone receptor expression in psoriasis. J Invest Dermatol (2007) 0.92

Left ventricular wall stress as a direct correlate of cardiomyocyte apoptosis in patients with severe dilated cardiomyopathy. Am Heart J (2003) 0.92

Licocalchone-C extracted from Glycyrrhiza glabra inhibits lipopolysaccharide-interferon-γ inflammation by improving antioxidant conditions and regulating inducible nitric oxide synthase expression. Molecules (2011) 0.92

Human mast cells stimulate activated T cells: implications for multiple sclerosis. Ann N Y Acad Sci (2008) 0.92

BRCA1 and BRCA2 status in a Central Sudanese series of breast cancer patients: interactions with genetic, ethnic and reproductive factors. Breast Cancer Res Treat (2007) 0.91

Reuse of liver graft from a brain dead recipient. Clin Transplant (2007) 0.91

Circulating monocyte chemoattractant protein-1 and early development of nephropathy in type 1 diabetes. Diabetes Care (2002) 0.91

Production of MCP-1 and RANTES in bladder cancer patients after bacillus Calmette-Guerin immunotherapy. Cancer Immunol Immunother (2002) 0.91

Phenotype modulation in cultures of vascular smooth muscle cells from diabetic rats: association with increased nitric oxide synthase expression and superoxide anion generation. J Cell Physiol (2003) 0.90

Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans. PLoS One (2012) 0.90

Regulation of IL-1-induced selective IL-6 release from human mast cells and inhibition by quercetin. Br J Pharmacol (2006) 0.90

Use of polyphenols in periodontal inflammation. Eur J Pharmacol (2013) 0.89

Niacin-induced "flush" involves release of prostaglandin D2 from mast cells and serotonin from platelets: evidence from human cells in vitro and an animal model. J Pharmacol Exp Ther (2008) 0.88

IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis. PLoS One (2012) 0.88

Enhanced expression of glia maturation factor correlates with glial activation in the brain of triple transgenic Alzheimer's disease mice. Neurochem Res (2012) 0.88

Stimulated human mast cells secrete mitochondrial components that have autocrine and paracrine inflammatory actions. PLoS One (2012) 0.88

Mitochondria distinguish granule-stored from de novo synthesized tumor necrosis factor secretion in human mast cells. Int Arch Allergy Immunol (2012) 0.88

IL-32 is increased along with tryptase in lesional psoriatic skin and is up-regulated by substance P in human mast cells. Eur J Dermatol (2010) 0.88

Interaction with culture medium components, cellular uptake and intracellular distribution of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts. Nanotoxicology (2012) 0.87

Flavones inhibit proliferation and increase mediator content in human leukemic mast cells (HMC-1). Eur J Haematol (2003) 0.87

Interleukin-16 network in inflammation and allergy. Allergy Asthma Proc (2002) 0.87

Stress-induced interleukin-6 release in mice is mast cell-dependent and more pronounced in Apolipoprotein E knockout mice. Cardiovasc Res (2003) 0.87