Evidence of Plasmodium falciparum malaria resistant to atovaquone and proguanil hydrochloride: case reports.

PubWeight™: 1.31‹?› | Rank: Top 10%

🔗 View Article (PMC 151974)

Published in BMJ on March 22, 2003

Authors

Anna Färnert1, Johan Lindberg, Pedro Gil, Göte Swedberg, Yngve Berqvist, Mita M Thapar, Niklas Lindegårdh, Sándor Berezcky, A Björkman

Author Affiliations

1: Department of Medicine, Division of Infectious Diseases, Karolinska Institute, Karolinska Hospital, S-171 76 Stockholm, Sweden. anna.farnert@medks.ki.se

Articles citing this

Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum. Antimicrob Agents Chemother (2004) 2.50

Malarone treatment failure not associated with previously described mutations in the cytochrome b gene. Malar J (2004) 1.23

Association of house spraying with suppressed levels of drug resistance in Zimbabwe. Malar J (2004) 1.16

Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa. Malar J (2006) 1.01

Novel Mutation in Cytochrome B of Plasmodium falciparum in One of Two Atovaquone-Proguanil Treatment Failures in Travelers Returning From Same Site in Nigeria. Open Forum Infect Dis (2014) 0.97

Plasmodium falciparum malaria and atovaquone-proguanil treatment failure. Emerg Infect Dis (2008) 0.93

Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium falciparum cytochrome b gene in Luanda, Angola. Malar J (2006) 0.92

In vitro atovaquone/proguanil susceptibility and characterization of the cytochrome b gene of Plasmodium falciparum from different endemic regions of Thailand. Malar J (2008) 0.88

Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1. Proc Natl Acad Sci U S A (2015) 0.85

First case of emergence of atovaquone-proguanil resistance in Plasmodium falciparum during treatment in a traveler in Comoros. Antimicrob Agents Chemother (2008) 0.84

Early treatment failure during treatment of Plasmodium falciparum malaria with atovaquone-proguanil in the Republic of Ivory Coast. Malar J (2012) 0.83

Sequence analysis of Plasmodium falciparum cytochrome b in multiple geographic sites. Malar J (2007) 0.83

Plasmodium falciparum drug resistance in Angola. Malar J (2016) 0.83

Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene. Malar J (2010) 0.80

Distinction of Plasmodium falciparum recrudescence and re-infection by MSP2 genotyping: a caution about unstandardized classification criteria. Malar J (2008) 0.78

Treatment of murine cerebral malaria by artemisone in combination with conventional antimalarial drugs: antiplasmodial effects and immune responses. Antimicrob Agents Chemother (2014) 0.77

Molecular characterization of the cytochrome b gene and in vitro atovaquone susceptibility of Plasmodium falciparum isolates from Kenya. Antimicrob Agents Chemother (2015) 0.76

Articles by these authors

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N Engl J Med (2014) 6.89

Intrahost modeling of artemisinin resistance in Plasmodium falciparum. Proc Natl Acad Sci U S A (2010) 4.50

Malaria eradication on islands. Lancet (2000) 3.51

Antibodies in malarial sera to parasite antigens in the membrane of erythrocytes infected with early asexual stages of Plasmodium falciparum. J Exp Med (1984) 3.49

How much fat is necessary to optimize lumefantrine oral bioavailability? Trop Med Int Health (2007) 3.13

Human antibodies to a Mr 155,000 Plasmodium falciparum antigen efficiently inhibit merozoite invasion. Proc Natl Acad Sci U S A (1984) 2.52

Guidelines for field surveys of the quality of medicines: a proposal. PLoS Med (2009) 2.36

Genotyping of Plasmodium falciparum infections by PCR: a comparative multicentre study. Trans R Soc Trop Med Hyg (2001) 2.34

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients. Arthritis Rheum (2010) 2.27

Chloroquine-resistant falciparum malaria in Madagascar and Kenya. Ann Trop Med Parasitol (1981) 2.03

Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast. PLoS One (2011) 2.00

Multiple dose pharmacokinetics of oral artemisinin and comparison of its efficacy with that of oral artesunate in falciparum malaria patients. Trans R Soc Trop Med Hyg (1996) 1.90

Epidemiology and clinical features of vivax malaria imported to Europe: sentinel surveillance data from TropNetEurop. Malar J (2004) 1.90

Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic. Clin Infect Dis (2004) 1.85

Pharmacokinetic study of artemether-lumefantrine given once daily for the treatment of uncomplicated multidrug-resistant falciparum malaria. Trop Med Int Health (2007) 1.82

Complexity of Plasmodium falciparum infections is consistent over time and protects against clinical disease in Tanzanian children. J Infect Dis (1999) 1.81

High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi. Acta Trop (2003) 1.80

Fever episodes in a holoendemic malaria area of Tanzania: parasitological and clinical findings and diagnostic aspects related to malaria. Trans R Soc Trop Med Hyg (1993) 1.79

Pitfalls in estimating piperaquine elimination. Antimicrob Agents Chemother (2005) 1.79

Dissection of the human antibody response to the malaria antigen Pf155/RESA into epitope specific components. Immunol Rev (1989) 1.73

Agranulocytosis associated with malaria prophylaxis with Maloprim. Br Med J (Clin Res Ed) (1983) 1.72

Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria. Antimicrob Agents Chemother (2012) 1.59

Long-term follow-up of Helicobacter pylori eradication therapy in Vietnam: reinfection and clinical outcome. Aliment Pharmacol Ther (2005) 1.59

Detection of a substantial number of sub-microscopic Plasmodium falciparum infections by polymerase chain reaction: a potential threat to malaria control and diagnosis in Ethiopia. Malar J (2013) 1.56

Malaria chemoprophylaxis with mefloquine. Lancet (1991) 1.55

Characterization of the humoral immune response in Plasmodium falciparum malaria. I. Estimation of antibodies to P. falciparum or human erythrocytes by means of microELISA. Clin Exp Immunol (1983) 1.54

Rabbit and human antibodies to a repeated amino acid sequence of a Plasmodium falciparum antigen, Pf 155, react with the native protein and inhibit merozoite invasion. Proc Natl Acad Sci U S A (1986) 1.51

Population pharmacokinetic assessment of a new regimen of mefloquine used in combination treatment of uncomplicated falciparum malaria. Antimicrob Agents Chemother (2006) 1.43

Malaria prophylaxis policy for travellers from Europe to the Indian Subcontinent. Malar J (2006) 1.42

Anti-Plasmodium falciparum antibodies acquired by residents in a holoendemic area of Liberia during development of clinical immunity. Am J Trop Med Hyg (1986) 1.40

Clinical efficacy and pharmacokinetics of artemisinin monotherapy and in combination with mefloquine in patients with falciparum malaria. Br J Clin Pharmacol (1996) 1.35

Sampling and storage of blood and the detection of malaria parasites by polymerase chain reaction. Trans R Soc Trop Med Hyg (1999) 1.34

On the question of dose-dependent chloroquine elimination of a single oral dose. Clin Pharmacol Ther (1983) 1.34

Pneumocystis carinii pneumonia: detection of parasites in sputum and bronchoalveolar lavage fluid by monoclonal antibodies. BMJ (1988) 1.34

Synergism of benflumetol and artemether in Plasmodium falciparum. Am J Trop Med Hyg (1999) 1.33

Regulation of the immune response in Plasmodium falciparum malaria. III. Proliferative response to antigen in vitro and subset composition of T cells from patients with acute infection or from immune donors. Clin Exp Immunol (1984) 1.32

Age as a risk factor for severe manifestations and fatal outcome of falciparum malaria in European patients: observations from TropNetEurop and SIMPID Surveillance Data. Clin Infect Dis (2003) 1.29

Feature detection and alignment of hyphenated chromatographic-mass spectrometric data. Extraction of pure ion chromatograms using Kalman tracking. J Chromatogr A (2008) 1.27

Population pharmacokinetics and pharmacodynamics of artemether and lumefantrine during combination treatment in children with uncomplicated falciparum malaria in Tanzania. Antimicrob Agents Chemother (2010) 1.27

Development and validation of an automated solid-phase extraction and liquid chromatographic method for determination of lumefantrine in capillary blood on sampling paper. J Pharm Biomed Anal (2007) 1.27

Malignant mesothelioma of the tunica vaginalis. Report of a case without risk factors and review of the literature. Int Urol Nephrol (2003) 1.26

Genetic markers associated with early cancer-specific mortality following prostatectomy. Cancer (2013) 1.25

A case-control study in northern Liberia of Plasmodium falciparum malaria in haemoglobin S and beta-thalassaemia traits. Ann Trop Med Parasitol (1983) 1.24

Risk of development of in vitro resistance to amoxicillin, clarithromycin, and metronidazole in Helicobacter pylori. Antimicrob Agents Chemother (1998) 1.24

Gene expression phenotypes of Arabidopsis associated with sensitivity to low temperatures. Plant Physiol (2003) 1.24

Determination of binding specificities in highly multiplexed bead-based assays for antibody proteomics. Mol Cell Proteomics (2006) 1.22

Predictive metabolite profiling applying hierarchical multivariate curve resolution to GC-MS data--a potential tool for multi-parametric diagnosis. J Proteome Res (2006) 1.21

In vitro activity of artemisinin, its derivatives, and pyronaridine against different strains of Plasmodium falciparum. Trans R Soc Trop Med Hyg (1991) 1.21

Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease. Immunol Lett (2008) 1.20

Second-order peak detection for multicomponent high-resolution LC/MS data. Anal Chem (2006) 1.20

Quinoline resistance associated polymorphisms in the pfcrt, pfmdr1 and pfmrp genes of Plasmodium falciparum in Iran. Acta Trop (2006) 1.19

Malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the Vanuatu Archipelago. Acta Trop (1998) 1.19

Different malaria control activities in an area of Liberia--effects on malariometric parameters. Ann Trop Med Parasitol (1985) 1.19

Higher IL-10 levels are associated with less effective clearance of Plasmodium falciparum parasites. Parasite Immunol (2004) 1.18

Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies. Expert Rev Anti Infect Ther (2009) 1.18

Identification of new differentially methylated genes that have potential functional consequences in prostate cancer. PLoS One (2012) 1.15

Lymphocyte activation and subset redistribution in the peripheral blood in acute malaria illness: distinct gammadelta+ T cell patterns in Plasmodium falciparum and P. vivax infections. Clin Exp Immunol (1997) 1.14

Falciparum malaria and beta-thalassaemia trait in northern Liberia. Ann Trop Med Parasitol (1983) 1.14

Automation of cDNA synthesis and labelling improves reproducibility. J Biomed Biotechnol (2009) 1.13

Increased mortality and morbidity associated with thyroidectomy for intrathoracic goiters reaching the carina tracheae. Arch Surg (2006) 1.12

Long-term survival in transfusion recipients in Sweden, 1993. Transfusion (2001) 1.12

Correlation network analysis for data integration and biomarker selection. Mol Biosyst (2008) 1.12

Genotyping of methicillin-resistant Staphylococcus aureus strains from two hospitals in Bangalore, South India. J Clin Microbiol (2005) 1.12

Functional connectivity in mild cognitive impairment during a memory task: implications for the disconnection hypothesis. J Alzheimers Dis (2010) 1.11

Human monoclonal antibodies to Pf 155, a major antigen of malaria parasite Plasmodium falciparum. Science (1986) 1.11

High and variable frequencies of CYP2C19 mutations: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands. Pharmacogenetics (1999) 1.09

Hypermethylation of the GABRE~miR-452~miR-224 promoter in prostate cancer predicts biochemical recurrence after radical prostatectomy. Clin Cancer Res (2014) 1.08

A comparison of methods for alignment of NMR peaks in the context of cluster analysis. J Pharm Biomed Anal (2005) 1.07

Polyclonal Plasmodium falciparum malaria in travelers and selection of antifolate mutations after proguanil prophylaxis. Am J Trop Med Hyg (2002) 1.06

Efficacy of artemether-lumefantrine in treatment of malaria among under-fives and prevalence of drug resistance markers in Igombe-Mwanza, north-western Tanzania. Malar J (2012) 1.05

Chloroquine treatment for uncomplicated childhood malaria in an area with drug resistance: early treatment failure aggravates anaemia. Trans R Soc Trop Med Hyg (1999) 1.05

Characterization of the humoral immune response in Plasmodium falciparum malaria. III. Factors influencing the coexpression of antibody isotypes (IgM and IgG-1 to 4). Clin Exp Immunol (1986) 1.05

Acute psychosis following mefloquine prophylaxis. Lancet (1989) 1.05

Similar rate of disease progression among individuals infected with HIV-1 genetic subtypes A-D. AIDS (1999) 1.05

In vitro interactions of artemisinin with atovaquone, quinine, and mefloquine against Plasmodium falciparum. Antimicrob Agents Chemother (2002) 1.04

Higher proportion of CD8+ T cells in the blood in healthy adults from Ethiopia and Bangladesh compared with Sweden. Trans R Soc Trop Med Hyg (1998) 1.04

pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquine. Antimicrob Agents Chemother (2012) 1.04

Response of Plasmodium falciparum to chloroquine treatment: relation to whole blood concentrations of chloroquine and desethylchloroquine. Bull World Health Organ (1989) 1.03

T-cell epitopes in Pf155/RESA, a major candidate for a Plasmodium falciparum malaria vaccine. Proc Natl Acad Sci U S A (1988) 1.03

Regional cerebral blood flow assessed with 99mTc-ECD SPET as a marker of progression of mild cognitive impairment to Alzheimer's disease. Eur J Nucl Med Mol Imaging (2003) 1.03

In vitro activity of chloroquine, the two enantiomers of chloroquine, desethylchloroquine and pyronaridine against Plasmodium falciparum. Br J Clin Pharmacol (1986) 1.03

Two distinct transport motifs in the adenovirus E3/10.4-14.5 proteins act in concert to down-modulate apoptosis receptors and the epidermal growth factor receptor. J Biol Chem (2003) 1.00

Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study. Arthritis Res Ther (2008) 1.00

Lack of effect of desipramine on the response to chloroquine of patients with chloroquine-resistant falciparum malaria. Trans R Soc Trop Med Hyg (1992) 1.00

Efficacy of artemisinin and mefloquine combinations against Plasmodium falciparum. In vitro simulation of in vivo pharmacokinetics. Trop Med Int Health (1997) 0.99

Focal temporoparietal slow activity in Alzheimer's disease revealed by magnetoencephalography. Biol Psychiatry (2002) 0.98

Micronutrient and iron supplementation and effective antimalarial treatment synergistically improve childhood anaemia. Trop Med Int Health (2000) 0.98

Isolation, characterization and standardization of a major metabolite of amodiaquine by chromatographic and spectroscopic methods. J Chromatogr (1986) 0.98

Identification of Pneumocystis carinii f. sp. hominis gene sequences in filtered air in hospital environments. J Clin Microbiol (1998) 0.98

Evaluation of three qualitative tests for detection of chloroquine in urine--agreement with plasma concentrations determined with liquid chromatography. Ann Trop Med Parasitol (1986) 0.98

Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations. Pharmacogenetics (1999) 0.97

Reliability of Dill-Glazko test. Lancet (1985) 0.97

High frequencies of CYP2C19 mutations and poor metabolism of proguanil in Vanuatu. Lancet (1997) 0.97

Human monocytes cultured with and without interferon-gamma inhibit Plasmodium falciparum parasite growth in vitro via secretion of reactive nitrogen intermediates. Parasite Immunol (1994) 0.97

A study on malaria infection during the acute stage of measles infection. J Trop Med Hyg (1991) 0.97

Signal pathways JNK and NF-kappaB, identified by global gene expression profiling, are involved in regulation of TNFalpha-induced mPGES-1 and COX-2 expression in gingival fibroblasts. BMC Genomics (2010) 0.97

Transmission of stress-induced learning impairment and associated brain gene expression from parents to offspring in chickens. PLoS One (2007) 0.97

A longitudinal study of antibodies to the Plasmodium falciparum antigen Pf155/RESA and immunity to malaria infection in adult Liberians. Trans R Soc Trop Med Hyg (1991) 0.96

A solution to the 1D NMR alignment problem using an extended generalized fuzzy Hough transform and mode support. Anal Bioanal Chem (2009) 0.96