Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.

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Published in N Engl J Med on November 26, 2014

Authors

Giulio Genovese1, Anna K Kähler, Robert E Handsaker, Johan Lindberg, Samuel A Rose, Samuel F Bakhoum, Kimberly Chambert, Eran Mick, Benjamin M Neale, Menachem Fromer, Shaun M Purcell, Oscar Svantesson, Mikael Landén, Martin Höglund, Sören Lehmann, Stacey B Gabriel, Jennifer L Moran, Eric S Lander, Patrick F Sullivan, Pamela Sklar, Henrik Grönberg, Christina M Hultman, Steven A McCarroll

Author Affiliations

1: The authors' affiliations are listed in the Appendix.

Associated clinical trials:

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies (EVITA) | NCT03682029

Aging of Hematopoietic Stem Cells - Molecular Architecture of Marrow Dysplasia and Clinical Contribution of Ineffective Hematopoiesis to Frailty in the Elderly | NCT03907553

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications | NCT04053439

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