Published in J Cell Sci on March 26, 2003
Human RAS superfamily proteins and related GTPases. Sci STKE (2004) 3.80
Gain-of-function mutations in RIT1 cause Noonan syndrome, a RAS/MAPK pathway syndrome. Am J Hum Genet (2013) 1.71
A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol Cell Biol (2006) 1.45
The novel GTPase Rit differentially regulates axonal and dendritic growth. J Neurosci (2007) 1.35
Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades. Mol Cell Biol (2005) 1.18
Rit signaling contributes to interferon-gamma-induced dendritic retraction via p38 mitogen-activated protein kinase activation. J Neurochem (2008) 0.91
Rit subfamily small GTPases: regulators in neuronal differentiation and survival. Cell Signal (2013) 0.90
Rit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction. Biochim Biophys Acta (2007) 0.84
Ras family small GTPase-mediated neuroprotective signaling in stroke. Cent Nerv Syst Agents Med Chem (2011) 0.79
Rit GTPase regulates a p38 MAPK-dependent neuronal survival pathway. Neurosci Lett (2012) 0.77
Ionizing Radiation Induces Altered Neuronal Differentiation by mGluR1 through PI3K-STAT3 Signaling in C17.2 Mouse Neural Stem-Like Cells. PLoS One (2016) 0.75
Altered mRNA Splicing in SMN-Depleted Motor Neuron-Like Cells. PLoS One (2016) 0.75
Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging. Proc Natl Acad Sci U S A (2007) 2.24
Regulation of voltage-gated calcium channel activity by the Rem and Rad GTPases. Proc Natl Acad Sci U S A (2003) 1.74
A novel cyclic AMP-dependent Epac-Rit signaling pathway contributes to PACAP38-mediated neuronal differentiation. Mol Cell Biol (2006) 1.45
Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated. J Clin Invest (2008) 1.40
The RGK family of GTP-binding proteins: regulators of voltage-dependent calcium channels and cytoskeleton remodeling. Cell Signal (2007) 1.40
Regulation of L-type Ca2+ channel activity and insulin secretion by the Rem2 GTPase. J Biol Chem (2005) 1.38
Tools to analyze protein farnesylation in cells. Bioconjug Chem (2005) 1.35
The novel GTPase Rit differentially regulates axonal and dendritic growth. J Neurosci (2007) 1.35
An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria. Hum Mol Genet (2010) 1.26
An evolutionarily conserved Rit GTPase-p38 MAPK signaling pathway mediates oxidative stress resistance. Mol Biol Cell (2011) 1.22
Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase. J Biol Chem (2006) 1.22
Altered expression of TRPV1 and sensitivity to capsaicin in pulmonary myelinated afferents following chronic airway inflammation in the rat. J Physiol (2008) 1.21
Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase. J Am Chem Soc (2002) 1.19
Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades. Mol Cell Biol (2005) 1.18
L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current. Am J Physiol Heart Circ Physiol (2006) 1.12
Induction of neurite extension and survival in pheochromocytoma cells by the Rit GTPase. J Biol Chem (2002) 1.11
Absence of progeria-like disease phenotypes in knock-in mice expressing a non-farnesylated version of progerin. Hum Mol Genet (2010) 1.09
Human intervertebral disc aggrecan inhibits nerve growth in vitro. Arthritis Rheum (2002) 1.07
Inhibition of Kinesin-5, a microtubule-based motor protein, as a strategy for enhancing regeneration of adult axons. Traffic (2011) 1.07
Plasma membrane targeting is essential for Rem-mediated Ca2+ channel inhibition. J Biol Chem (2007) 1.06
Rem GTPase interacts with the proximal CaV1.2 C-terminus and modulates calcium-dependent channel inactivation. Channels (Austin) (2010) 1.06
Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments. J Neurotrauma (2014) 1.05
Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry (2006) 1.03
Cdc20 is required for the post-anaphase, KEN-dependent degradation of centromere protein F. J Cell Sci (2010) 1.01
Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria. J Lipid Res (2009) 1.01
Mammalian-produced chondroitinase AC mitigates axon inhibition by chondroitin sulfate proteoglycans. J Neurochem (2007) 0.99
Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity. Chembiochem (2008) 0.99
A potent HIV protease inhibitor, darunavir, does not inhibit ZMPSTE24 or lead to an accumulation of farnesyl-prelamin A in cells. J Biol Chem (2008) 0.99
A tagging-via-substrate approach to detect the farnesylated proteome using two-dimensional electrophoresis coupled with Western blotting. Mol Cell Proteomics (2010) 0.97
Rin GTPase couples nerve growth factor signaling to p38 and b-Raf/ERK pathways to promote neuronal differentiation. J Biol Chem (2005) 0.97
Cocaine exposure in vitro induces apoptosis in fetal locus coeruleus neurons through TNF-alpha-mediated induction of Bax and phosphorylated c-Jun NH(2)-terminal kinase. J Neurochem (2007) 0.96
Nerve growth factor-dependent activation of the small GTPase Rin. J Biol Chem (2002) 0.95
A rit GTPase-p38 mitogen-activated protein kinase survival pathway confers resistance to cellular stress. Mol Cell Biol (2011) 0.94
Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids. Cell Signal (2007) 0.94
Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues. Biochemistry (2007) 0.93
The cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium. Am J Physiol Heart Circ Physiol (2012) 0.92
Rit subfamily small GTPases: regulators in neuronal differentiation and survival. Cell Signal (2013) 0.90
Directed library of anilinogeranyl analogues of farnesyl diphosphate via mixed solid- and solution-phase synthesis. Org Lett (2005) 0.89
Rem-GTPase regulates cardiac myocyte L-type calcium current. Channels (Austin) (2012) 0.88
Activating the synthesis of progerin, the mutant prelamin A in Hutchinson-Gilford progeria syndrome, with antisense oligonucleotides. Hum Mol Genet (2009) 0.88
Farnesyl diphosphate analogues with aryl moieties are efficient alternate substrates for protein farnesyltransferase. Biochemistry (2012) 0.88
Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24. J Lipid Res (2012) 0.88
Pituitary adenylate cyclase-activating polypeptide 38-mediated Rin activation requires Src and contributes to the regulation of HSP27 signaling during neuronal differentiation. Mol Cell Biol (2008) 0.87
Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. Bioorg Med Chem Lett (2004) 0.87
Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation. Mol Biol Cell (2010) 0.86
Extracellular signal-regulated kinases regulate dendritic growth in rat sympathetic neurons. J Neurosci (2004) 0.86
Prenatal intravenous cocaine and the heart rate-orienting response: a dose-response study. Int J Dev Neurosci (2004) 0.85
A semi-automated image analysis method to quantify neurite preference/axon guidance on a patterned substratum. J Neurosci Methods (2002) 0.85
Steady-state coupling of plasma membrane calcium entry to extrusion revealed by novel L-type calcium channel block. Cell Calcium (2008) 0.84
Prenatal cocaine exposure alters alpha2 receptor expression in adolescent rats. BMC Neurosci (2006) 0.84
Rit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction. Biochim Biophys Acta (2007) 0.84
Rit-mediated stress resistance involves a p38-mitogen- and stress-activated protein kinase 1 (MSK1)-dependent cAMP response element-binding protein (CREB) activation cascade. J Biol Chem (2012) 0.83
Rit GTPase signaling promotes immature hippocampal neuronal survival. J Neurosci (2012) 0.83
Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release. Biochemistry (2007) 0.83
Activated RIC, a small GTPase, genetically interacts with the Ras pathway and calmodulin during Drosophila development. Dev Dyn (2005) 0.82
Comparison of sensory neuron growth cone and filopodial responses to structurally diverse aggrecan variants, in vitro. Exp Neurol (2013) 0.82
Characterization of RERG: an estrogen-regulated tumor suppressor gene. Methods Enzymol (2006) 0.81
Rad GTPase deletion increases L-type calcium channel current leading to increased cardiac contraction. J Am Heart Assoc (2013) 0.81
Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome. J Lipid Res (2008) 0.80
Proximal versus distal cue utilization in preweanling spatial localization: the influence of cue number and location. Physiol Behav (2003) 0.79
Ras family small GTPase-mediated neuroprotective signaling in stroke. Cent Nerv Syst Agents Med Chem (2011) 0.79
Calmodulin binding is dispensable for Rem-mediated Ca2+ channel inhibition. Mol Cell Biochem (2007) 0.78
Rit GTPase regulates a p38 MAPK-dependent neuronal survival pathway. Neurosci Lett (2012) 0.77
Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling. PLoS One (2012) 0.77
Mechanisms regulating interpretation of guidance cues during development, maturation, and following injury. Rev Neurosci (2008) 0.77
Method for Shipping Live Cultures of Dissociated Rat Hippocampal Neurons. Curr Neurobiol (2010) 0.76
Putting the Rit in cellular resistance: Rit, p38 MAPK and oxidative stress. Commun Integr Biol (2013) 0.75
Microglia enhance dorsal root ganglion outgrowth in Schwann cell cultures. Glia (2004) 0.75