Published in Proc Natl Acad Sci U S A on April 02, 2003
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The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death. Development (2008) 1.14
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Epigenetic telomere protection by Drosophila DNA damage response pathways. PLoS Genet (2006) 1.10
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Drosophila p53 is required to increase the levels of the dKDM4B demethylase after UV-induced DNA damage to demethylate histone H3 lysine 9. J Biol Chem (2010) 0.97
Drosophila dCBP is involved in establishing the DNA replication checkpoint. Mol Cell Biol (2006) 0.97
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Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation. Genetics (2005) 0.96
Contribution of growth and cell cycle checkpoints to radiation survival in Drosophila. Genetics (2006) 0.94
Ultraviolet irradiation-induced K(+) channel activity involving p53 activation in corneal epithelial cells. Oncogene (2005) 0.93
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Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells. Dis Model Mech (2011) 0.88
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p53 activity is selectively licensed in the Drosophila stem cell compartment. Elife (2014) 0.87
Identification of dAven, a Drosophila melanogaster ortholog of the cell cycle regulator Aven. Cell Cycle (2011) 0.86
TATA binding protein associated factor 3 (TAF3) interacts with p53 and inhibits its function. BMC Mol Biol (2008) 0.84
p53 binding prevents phosphatase-mediated inactivation of diphosphorylated c-Jun N-terminal kinase. J Biol Chem (2012) 0.83
BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing. RNA (2012) 0.82
Concentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogaster. PLoS One (2012) 0.82
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Chk2 and p53 are haploinsufficient with dependent and independent functions to eliminate cells after telomere loss. PLoS Genet (2011) 0.81
Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster. Mech Ageing Dev (2010) 0.81
Hid arbitrates collective cell death in the Drosophila wing. Mech Dev (2015) 0.78
Chk2 and p53 regulate the transmission of healed chromosomes in the Drosophila male germline. PLoS Genet (2014) 0.78
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The function of Drosophila p53 isoforms in apoptosis. Cell Death Differ (2015) 0.77
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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell (1993) 33.20
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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell (1995) 14.90
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Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell (1995) 12.39
A model for p53-induced apoptosis. Nature (1997) 11.38
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma (1997) 11.04
PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell (2001) 11.04
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science (2000) 8.74
Gene targeting by homologous recombination in Drosophila. Science (2000) 8.63
PUMA induces the rapid apoptosis of colorectal cancer cells. Mol Cell (2001) 7.95
Oncogenic forms of p53 inhibit p53-regulated gene expression. Science (1992) 6.73
Presence of a potent transcription activating sequence in the p53 protein. Science (1990) 6.38
Dissecting p53 tumor suppressor functions in vivo. Cancer Cell (2002) 6.24
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The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev (1995) 5.68
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature (1994) 4.77
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Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev (2002) 4.21
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots. Genes Dev (1993) 3.99
Drosophila p53 binds a damage response element at the reaper locus. Cell (2000) 3.92
Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms. Science (1995) 3.69
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication. Cell (1991) 3.59
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Maintaining genetic stability through TP53 mediated checkpoint control. Cancer Surv (1997) 1.41
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sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr Biol (2002) 1.20
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Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span. Curr Biol (2005) 1.78
A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans. Genes Dev (2013) 1.62
Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death. Development (2006) 1.50
Eiger and its receptor, Wengen, comprise a TNF-like system in Drosophila. Oncogene (2003) 1.42
Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark. EMBO J (2002) 1.38
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Meiotic recombination provokes functional activation of the p53 regulatory network. Science (2010) 1.27
The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid. Curr Biol (2002) 1.21
The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death. Development (2008) 1.14
Noncanonical cell death pathways act during Drosophila oogenesis. Genesis (2007) 0.99
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A collective form of cell death requires homeodomain interacting protein kinase. J Cell Biol (2007) 0.98
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p53 activity is selectively licensed in the Drosophila stem cell compartment. Elife (2014) 0.87
Tango7 directs cellular remodeling by the Drosophila apoptosome. Genes Dev (2013) 0.82
A cell-based screening platform identifies novel mosquitocidal toxins. J Biomol Screen (2013) 0.76