Mechanism of proton transport in bacteriorhodopsin from crystallographic structures of the K, L, M1, M2, and M2' intermediates of the photocycle.

PubWeight™: 1.62‹?› | Rank: Top 4%

🔗 View Article (PMID 12691752)

Published in J Mol Biol on April 25, 2003

Authors

Janos K Lanyi1, Brigitte Schobert

Author Affiliations

1: Department of Physiology and Biophysics, University of California, 346D Medical Science I, Irvine, CA 92697, USA. jlanyi@orion.oac.uci.edu

Articles citing this

Bi-stable neural state switches. Nat Neurosci (2008) 4.69

Functional and shunt states of bacteriorhodopsin resolved by 250 GHz dynamic nuclear polarization-enhanced solid-state NMR. Proc Natl Acad Sci U S A (2009) 2.45

Energy transformations early in the bacteriorhodopsin photocycle revealed by DNP-enhanced solid-state NMR. Proc Natl Acad Sci U S A (2008) 2.07

Xanthorhodopsin: a proton pump with a light-harvesting carotenoid antenna. Science (2005) 1.90

Proton binding within a membrane protein by a protonated water cluster. Proc Natl Acad Sci U S A (2005) 1.36

Time-resolved structural studies of protein reaction dynamics: a smorgasbord of X-ray approaches. Acta Crystallogr A (2010) 1.23

Structural changes in the L photointermediate of bacteriorhodopsin. J Mol Biol (2006) 1.11

pH dependence of light-driven proton pumping by an archaerhodopsin from Tibet: comparison with bacteriorhodopsin. Biophys J (2006) 1.04

Direct measurement of proton release by cytochrome c oxidase in solution during the F-->O transition. Proc Natl Acad Sci U S A (2004) 1.04

Bacteriorhodopsin photocycle at cryogenic temperatures reveals distributed barriers of conformational substates. Proc Natl Acad Sci U S A (2007) 1.02

Protein conformational changes in the bacteriorhodopsin photocycle: comparison of findings from electron and X-ray crystallographic analyses. PLoS One (2009) 0.98

Amino acids with an intermolecular proton bond as proton storage site in bacteriorhodopsin. Proc Natl Acad Sci U S A (2008) 0.98

A priori resolution of the intermediate spectra in the bacteriorhodopsin photocycle: the time evolution of the L spectrum revealed. J Phys Chem A (2006) 0.97

The energetics of the primary proton transfer in bacteriorhodopsin revisited: it is a sequential light-induced charge separation after all. Biochim Biophys Acta (2008) 0.96

Structural snapshots of conformational changes in a seven-helix membrane protein: lessons from bacteriorhodopsin. Curr Opin Struct Biol (2009) 0.95

DNP enhanced frequency-selective TEDOR experiments in bacteriorhodopsin. J Magn Reson (2009) 0.92

Water structural changes in the L and M photocycle intermediates of bacteriorhodopsin as revealed by time-resolved step-scan Fourier transform infrared (FTIR) spectroscopy. Biochemistry (2007) 0.92

Structure, dynamics and reactions of protein hydration water. Philos Trans R Soc Lond B Biol Sci (2004) 0.89

How environment supports a state: molecular dynamics simulations of two states in bacteriorhodopsin suggest lipid and water compensation. Biophys J (2004) 0.88

Conformational changes in the archaerhodopsin-3 proton pump: detection of conserved strongly hydrogen bonded water networks. J Biol Phys (2011) 0.88

Time-resolved microspectroscopy on a single crystal of bacteriorhodopsin reveals lattice-induced differences in the photocycle kinetics. Biophys J (2006) 0.84

External electric control of the proton pumping in bacteriorhodopsin. Eur Biophys J (2006) 0.83

Propagating structural perturbation inside bacteriorhodopsin: crystal structures of the M state and the D96A and T46V mutants. Biochemistry (2006) 0.82

Aborted double bicycle-pedal isomerization with hydrogen bond breaking is the primary event of bacteriorhodopsin proton pumping. Proc Natl Acad Sci U S A (2010) 0.81

Electron paramagnetic resonance study of structural changes in the O photointermediate of bacteriorhodopsin. J Mol Biol (2006) 0.81

Recent advances in engineering microbial rhodopsins for optogenetics. Curr Opin Struct Biol (2015) 0.80

Excitation of the L intermediate of bacteriorhodopsin: electric responses to test x-ray structures. Biophys J (2006) 0.80

Role of Arg82 in the early steps of the bacteriorhodopsin proton-pumping cycle. J Phys Chem B (2011) 0.79

Hydration dependence of active core fluctuations in bacteriorhodopsin. Biophys J (2008) 0.79

Role of Arg-72 of pharaonis Phoborhodopsin (sensory rhodopsin II) on its photochemistry. Biophys J (2004) 0.78

Actinic light-energy dependence of proton release from bacteriorhodopsin. Biophys J (2005) 0.78

Can the low-resolution structures of photointermediates of bacteriorhodopsin explain their crystal structures? Biophys J (2004) 0.77

Dynamic mechanism of proton transfer in mannitol 2-dehydrogenase from Pseudomonas fluorescens: mobile GLU292 controls proton relay through a water channel that connects the active site with bulk solvent. J Biol Chem (2011) 0.76

Structure of archaerhodopsin-2 at 1.8 Å resolution. Acta Crystallogr D Biol Crystallogr (2014) 0.76

Structural transition of bacteriorhodopsin is preceded by deprotonation of Schiff base: microsecond time-resolved x-ray diffraction study of purple membrane. Biophys J (2004) 0.76

Structural changes in bacteriorhodopsin during in vitro refolding from a partially denatured state. Biophys J (2011) 0.76

Complex Photochemistry within the Green-Absorbing Channelrhodopsin ReaChR. Biophys J (2017) 0.75

Fast, triangular voltage clamp for recording and kinetic analysis of an ion transporter expressed in Xenopus oocytes. Biophys J (2005) 0.75