Published in Mol Pharmacol on May 01, 2003
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev (2005) 1.52
3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. J Biol Chem (2013) 1.05
CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity. J Biol Chem (2010) 0.93
Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells. Biochem J (2003) 0.86
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem Cell Biol (2013) 0.85
Identification of cytotoxic agents disrupting synovial sarcoma oncoprotein interactions by proximity ligation assay. Oncotarget (2016) 0.80
Targeting human telomerase for cancer therapeutics. Cytotechnology (2004) 0.79
Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene. Sarcoma (2012) 0.78
Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles. Nucleic Acids Res (2015) 0.77
Nitropropenyl benzodioxole, an anti-infective agent with action as a protein tyrosine phosphatase inhibitor. Open Med Chem J (2014) 0.75
β-Nitrostyrenes as Potential Anti-leishmanial Agents. Front Microbiol (2016) 0.75
Differential effects of nitrostyrene derivatives on myelopoiesis involve regulation of C/EBPα and p38MAPK activity. PLoS One (2014) 0.75
Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms. J Gastroenterol Hepatol (2006) 2.04
Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection. Ann N Y Acad Sci (2005) 2.03
Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. Cell Immunol (2009) 1.90
Genome-wide association study of childhood acute lymphoblastic leukemia in Korea. Leuk Res (2010) 1.85
Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death. Brain (2008) 1.65
Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab (2007) 1.60
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev (2005) 1.52
Genetic polymorphisms of NOS3 are associated with the risk of invasive breast cancer with lymph node involvement. Breast Cancer Res Treat (2007) 1.45
[The diagnostic validity of Helicobacter pylori stool antigen test in the pre- and post-eradication]. Korean J Gastroenterol (2004) 1.41
HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans. Arthritis Rheum (2009) 1.36
Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases. J Am Chem Soc (2010) 1.18
Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes. PLoS One (2013) 1.18
A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population. Hum Mol Genet (2010) 1.17
The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. J Neurosci (2006) 1.16
Single-stranded DNA binding factor AtWHY1 modulates telomere length homeostasis in Arabidopsis. Plant J (2007) 1.15
Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One (2009) 1.15
Constitutive RelA activation mediated by Nkx3.2 controls chondrocyte viability. Nat Cell Biol (2007) 1.10
Association of the 276G->T polymorphism of the adiponectin gene with cardiovascular disease risk factors in nondiabetic Koreans. Am J Clin Nutr (2005) 1.09
Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery. Hum Mol Genet (2010) 1.06
The -1131T-->C polymorphism in the apolipoprotein A5 gene is associated with postprandial hypertriacylglycerolemia; elevated small, dense LDL concentrations; and oxidative stress in nonobese Korean men. Am J Clin Nutr (2004) 1.03
Suppression of RICE TELOMERE BINDING PROTEIN 1 results in severe and gradual developmental defects accompanied by genome instability in rice. Plant Cell (2007) 1.03
Endoscopic resection of duodenal neoplasms: a single-center study. Surg Endosc (2010) 1.02
Nuclear import of hTERT requires a bipartite nuclear localization signal and Akt-mediated phosphorylation. J Cell Sci (2012) 1.01
Synthesis of 6-formyl-pyridine-2-carboxylate derivatives and their telomerase inhibitory activities. Bioorg Med Chem Lett (2003) 1.00
Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line. BMC Neurosci (2007) 0.99
FasL shedding is reduced by hypothermia in experimental stroke. J Neurochem (2008) 0.99
Interaction of an Arabidopsis RNA-binding protein with plant single-stranded telomeric DNA modulates telomerase activity. J Biol Chem (2003) 0.98
Fermented garlic protects diabetic, obese mice when fed a high-fat diet by antioxidant effects. Nutr Res (2011) 0.97
Characterization, in vitro cytotoxicity assessment, and in vivo visualization of multimodal, RITC-labeled, silica-coated magnetic nanoparticles for labeling human cord blood-derived mesenchymal stem cells. Nanomedicine (2009) 0.97
Chronic tibiofibular syndesmosis injury of ankle: evaluation with contrast-enhanced fat-suppressed 3D fast spoiled gradient-recalled acquisition in the steady state MR imaging. Radiology (2007) 0.97
Agmatine: clinical applications after 100 years in translation. Drug Discov Today (2013) 0.96
Mail education is as effective as in-class education in hypertensive Korean patients. J Clin Hypertens (Greenwich) (2008) 0.96
Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1. J Biol Chem (2009) 0.96
Soybeans ameliolate diabetic nephropathy in rats. Evid Based Complement Alternat Med (2008) 0.95
A haplotype analysis of HER-2 gene polymorphisms: association with breast cancer risk, HER-2 protein expression in the tumor, and disease recurrence in Korea. Clin Cancer Res (2005) 0.95
CASP8 polymorphisms, estrogen and progesterone receptor status, and breast cancer risk. Breast Cancer Res Treat (2007) 0.94
DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase. J Biol Chem (2004) 0.93
Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation. J Biol Chem (2008) 0.93
Novel polymorphisms in the SUV39H2 histone methyltransferase and the risk of lung cancer. Carcinogenesis (2006) 0.93
CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity. J Biol Chem (2010) 0.93
Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. PLoS Genet (2012) 0.92
Agmatine inhibits matrix metalloproteinase-9 via endothelial nitric oxide synthase in cerebral endothelial cells. Neurol Res (2007) 0.92
Cell cycle-dependent regulation of telomerase activity by auxin, abscisic acid and protein phosphorylation in tobacco BY-2 suspension culture cells. Plant J (2002) 0.92
Sequence-specific binding to telomeric DNA by CEH-37, a homeodomain protein in the nematode Caenorhabditis elegans. J Biol Chem (2003) 0.91
Genetic polymorphism of interferon-gamma, interferon-gamma receptor, and interferon regulatory factor-1 genes in patients with hepatitis B virus infection. Biochem Genet (2006) 0.91
Effect of propofol post-treatment on blood-brain barrier integrity and cerebral edema after transient cerebral ischemia in rats. Neurochem Res (2013) 0.90
Decreased macrophage density on carbon nanotube patterns on polycarbonate urethane. J Biomed Mater Res A (2009) 0.90
Restoration of senescent human diploid fibroblasts by modulation of the extracellular matrix. Aging Cell (2011) 0.89
Lack of association between hepatitis B virus infection and polymorphism of mannose-binding lectin gene in Korean population. J Korean Med Sci (2005) 0.89
Genotypes and haplotypes of beta2-adrenergic receptor and parameters of the metabolic syndrome in Korean adolescents. Metabolism (2008) 0.89
Endoscopic findings and clinical features of esophageal tuberculosis. Scand J Gastroenterol (2010) 0.89
Experiences and challenges of informal caregiving for Korean immigrants. J Adv Nurs (2008) 0.89
Chaperone-like activity of high-mobility group box 1 protein and its role in reducing the formation of polyglutamine aggregates. J Immunol (2013) 0.89
Pulse pressure variation as a predictor of fluid responsiveness during one-lung ventilation for lung surgery using thoracotomy: randomised controlled study. Eur J Anaesthesiol (2011) 0.88
Agmatine attenuates brain edema through reducing the expression of aquaporin-1 after cerebral ischemia. J Cereb Blood Flow Metab (2009) 0.88
Three-dimensional surface models of detailed lumbosacral structures reconstructed from the Visible Korean. Ann Anat (2010) 0.87
Radicicol represses the transcriptional function of the estrogen receptor by suppressing the stabilization of the receptor by heat shock protein 90. Mol Cell Endocrinol (2002) 0.87
Reperfusion cellular injury in an animal model of transient ischemia. AJNR Am J Neuroradiol (2004) 0.86
Syntheses and biological activities of rebeccamycin analogues with uncommon sugars. J Med Chem (2005) 0.86
Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells. Biochem J (2012) 0.86
The 70 kDa heat shock protein protects against experimental traumatic brain injury. Neurobiol Dis (2013) 0.86
Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells. Biochem J (2003) 0.86
Mitochondrial DNA sequence variation of the swallowtail butterfly, Papilio xuthus, and the cabbage butterfly, Pieris rapae. Biochem Genet (2009) 0.85
RANTES, MCP-1, CCR2, CCR5, CXCR1 and CXCR4 gene polymorphisms are not associated with the outcome of hepatitis B virus infection: results from a large scale single ethnic population. J Korean Med Sci (2007) 0.85
Differentiation linked regulation of telomerase activity by Makorin-1. Mol Cell Biochem (2010) 0.85
Appendicitis during Pregnancy: The Clinical Experience of a Secondary Hospital. J Korean Soc Coloproctol (2012) 0.85
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase. Histochem Cell Biol (2013) 0.85
Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection. Aging Cell (2011) 0.85
Agmatine protects cultured retinal ganglion cells from tumor necrosis factor-alpha-induced apoptosis. Life Sci (2008) 0.85
Striatal-enriched protein tyrosine phosphatase regulates dopaminergic neuronal development via extracellular signal-regulated kinase signaling. Exp Neurol (2008) 0.85
Regulation of endothelial nitric oxide synthase by agmatine after transient global cerebral ischemia in rat brain. Anat Cell Biol (2010) 0.85
Induced expression of insulin-like growth factor-1 by amniotic membrane-conditioned medium in cultured human corneal epithelial cells. Invest Ophthalmol Vis Sci (2006) 0.85
Implications of Optic Disc Tilt in the Progression of Primary Open-Angle Glaucoma. Invest Ophthalmol Vis Sci (2015) 0.84
[The clinical usefulness of balloon occluded retrograde transvenous obliteration in gastric variceal bleeding]. Taehan Kan Hakhoe Chi (2003) 0.84
Cerebroprotective effects of red ginseng extract pretreatment against ischemia-induced oxidative stress and apoptosis. Int J Neurosci (2013) 0.84
Telomeric DNA damage by topoisomerase I. A possible mechanism for cell killing by camptothecin. J Biol Chem (2004) 0.84
MSX1 polymorphism associated with risk of oral cleft in Korea: evidence from case-parent trio and case-control studies. Yonsei Med J (2007) 0.84
Overexpression of a novel cell cycle regulator ecdysoneless in breast cancer: a marker of poor prognosis in HER2/neu-overexpressing breast cancer patients. Breast Cancer Res Treat (2012) 0.84
Retroviral expression of arginine decarboxylase attenuates oxidative burden in mouse cortical neural stem cells. Stem Cells Dev (2010) 0.84
Zinc induces cell death in immortalized embryonic hippocampal cells via activation of Akt-GSK-3beta signaling. Exp Cell Res (2006) 0.84
Neuroprotective effects of agmatine on oxygen-glucose deprived primary-cultured astrocytes and nuclear translocation of nuclear factor-kappa B. Brain Res (2009) 0.84
Protective effects of agmatine on lipopolysaccharide-injured microglia and inducible nitric oxide synthase activity. Life Sci (2012) 0.83
Solution structure of the DNA binding domain of rice telomere binding protein RTBP1. Biochemistry (2009) 0.83
GSTP1 polymorphism, cigarette smoking and cervical cancer risk in Korean women. Yonsei Med J (2002) 0.83
Genetic factors associated with response to intravitreal ranibizumab in Korean patients with neovascular age-related macular degeneration. Retina (2014) 0.83
Endogenous agmatine inhibits cerebral vascular matrix metalloproteinases expression by regulating activating transcription factor 3 and endothelial nitric oxide synthesis. Curr Neurovasc Res (2010) 0.83
Expression of the telomeric repeat binding factor gene NgTRF1 is closely coordinated with the cell division program in tobacco BY-2 suspension culture cells. J Biol Chem (2003) 0.83
Syntheses and biological activities of disaccharide daunorubicins. J Med Chem (2005) 0.83
Down-regulation of DNA topoisomerase IIalpha in human colorectal carcinoma cells resistant to a protoberberine alkaloid, berberrubine. Mol Pharmacol (2002) 0.83
p300-mediated acetylation of TRF2 is required for maintaining functional telomeres. Nucleic Acids Res (2013) 0.83
Effects of agmatine on hypoxic microglia and activity of nitric oxide synthase. Brain Res (2010) 0.82
Effects of constraint-induced movement therapy on neurogenesis and functional recovery after early hypoxic-ischemic injury in mice. Dev Med Child Neurol (2011) 0.82
Carbon nanotubes impregnated with subventricular zone neural progenitor cells promotes recovery from stroke. Int J Nanomedicine (2012) 0.82
A novel telomere elongation in an adriamycin-resistant stomach cancer cell line with decreased telomerase activity. Mol Cells (2002) 0.82
Enhancement of anti-inflammatory and antinociceptive actions of red ginseng extract by fermentation. J Pharm Pharmacol (2012) 0.82
Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT. Cancer Lett (2009) 0.82
Agmatine enhances neurogenesis by increasing ERK1/2 expression, and suppresses astrogenesis by decreasing BMP 2,4 and SMAD 1,5,8 expression in subventricular zone neural stem cells. Life Sci (2011) 0.82
The effects of a cognitive-behavioral therapy on career attitude maturity, decision making style, and self-esteem of nursing students in Korea. Nurse Educ Today (2010) 0.82