Published in Exp Eye Res on May 01, 2003
Investigation in Corneal Sensation and Contact Lens Wear | NCT04804592
Dry eye disease: an immune-mediated ocular surface disorder. Arch Ophthalmol (2012) 2.23
Change in prostaglandin expression levels and synthesizing activities in dry eye disease. Ophthalmology (2012) 2.07
Neural regulation of lacrimal gland secretory processes: relevance in dry eye diseases. Prog Retin Eye Res (2009) 2.04
Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases. Annu Rev Nutr (2011) 1.88
Early loss of innervation of cornea epithelium in streptozotocin-induced type 1 diabetic rats: improvement with ilepatril treatment. Invest Ophthalmol Vis Sci (2012) 1.77
Degeneration and regeneration of corneal nerves in response to HSV-1 infection. Invest Ophthalmol Vis Sci (2015) 1.59
Corneal confocal microscopy detects early nerve regeneration in diabetic neuropathy after simultaneous pancreas and kidney transplantation. Diabetes (2012) 1.50
In vivo confocal microscopy of corneal nerves: analysis and clinical correlation. Semin Ophthalmol (2010) 1.47
Contralateral Clinically Unaffected Eyes of Patients With Unilateral Infectious Keratitis Demonstrate a Sympathetic Immune Response. Invest Ophthalmol Vis Sci (2015) 1.45
In Vivo Confocal Microscopy Demonstrates Bilateral Loss of Endothelial Cells in Unilateral Herpes Simplex Keratitis. Invest Ophthalmol Vis Sci (2015) 1.40
Wounding the cornea to learn how it heals. Exp Eye Res (2014) 1.33
Femtosecond laser in laser in situ keratomileusis. J Cataract Refract Surg (2010) 1.32
Mapping the entire human corneal nerve architecture. Exp Eye Res (2010) 1.31
A novel mouse model for neurotrophic keratopathy: trigeminal nerve stereotactic electrolysis through the brain. Invest Ophthalmol Vis Sci (2011) 1.27
IL-17 and VEGF are necessary for efficient corneal nerve regeneration. Am J Pathol (2011) 1.21
Unilateral herpes zoster ophthalmicus results in bilateral corneal nerve alteration: an in vivo confocal microscopy study. Ophthalmology (2012) 1.20
Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA. Invest Ophthalmol Vis Sci (2009) 1.20
In vivo confocal microscopy of corneal small fiber damage in diabetes mellitus. Graefes Arch Clin Exp Ophthalmol (2010) 1.14
Subbasal nerve density and corneal sensitivity after laser in situ keratomileusis: femtosecond laser vs mechanical microkeratome. Arch Ophthalmol (2010) 1.13
Corneal nerves in health and disease. Surv Ophthalmol (2014) 1.12
Diagnosis and management of neurotrophic keratitis. Clin Ophthalmol (2014) 1.11
Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease. Invest Ophthalmol Vis Sci (2010) 1.10
Long-term comparison of full-bed deep anterior lamellar keratoplasty and penetrating keratoplasty in treating keratoconus. J Zhejiang Univ Sci B (2013) 1.08
Significance of lipid mediators in corneal injury and repair. J Lipid Res (2009) 1.08
Omega-3 fatty acids in dry eye and corneal nerve regeneration after refractive surgery. Prostaglandins Leukot Essent Fatty Acids (2010) 1.07
Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia. PLoS One (2013) 1.06
Lacritin, a novel human tear glycoprotein, promotes sustained basal tearing and is well tolerated. Invest Ophthalmol Vis Sci (2011) 1.06
Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist. Pain (2010) 1.06
Repeated monitoring of corneal nerves by confocal microscopy as an index of peripheral neuropathy in type-1 diabetic rodents and the effects of topical insulin. J Peripher Nerv Syst (2013) 1.04
Corneal nerve fiber pathology in Japanese type 1 diabetic patients and its correlation with antecedent glycemic control and blood pressure. J Diabetes Investig (2012) 1.03
Mapping the nerve architecture of diabetic human corneas. Ophthalmology (2012) 1.02
Neuropathic ocular pain: an important yet underevaluated feature of dry eye. Eye (Lond) (2014) 1.00
Critical appraisal of ex vivo expansion of human limbal epithelial stem cells. Curr Mol Med (2010) 0.99
Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery. Invest Ophthalmol Vis Sci (2013) 0.99
Corneal confocal microscopy to assess diabetic neuropathy: an eye on the foot. J Diabetes Sci Technol (2013) 0.98
Developmental corneal innervation: interactions between nerves and specialized apical corneal epithelial cells. Invest Ophthalmol Vis Sci (2009) 0.97
Corneal nerve alterations in acute Acanthamoeba and fungal keratitis: an in vivo confocal microscopy study. Eye (Lond) (2011) 0.97
Developmental guidance of embryonic corneal innervation: roles of Semaphorin3A and Slit2. Dev Biol (2010) 0.96
Differential gene expression patterns of the developing and adult mouse cornea compared to the lens and tendon. Exp Eye Res (2008) 0.96
Post-LASIK tear dysfunction and dysesthesia. Ocul Surf (2010) 0.95
Control of patterns of corneal innervation by Pax6. Invest Ophthalmol Vis Sci (2008) 0.94
Autonomic control of the eye. Compr Physiol (2015) 0.93
Confocal comparison of corneal reinnervation after small incision lenticule extraction (SMILE) and femtosecond laser in situ keratomileusis (FS-LASIK). PLoS One (2013) 0.93
Corneal confocal microscopy detects small-fiber neuropathy in Charcot-Marie-Tooth disease type 1A patients. Muscle Nerve (2012) 0.93
Autoimmunity at the ocular surface: pathogenesis and regulation. Mucosal Immunol (2010) 0.93
Corneal subbasal nerve density: a comparison of two confocal microscopes. Eye Contact Lens (2008) 0.93
Innervation of the mouse cornea during development. Invest Ophthalmol Vis Sci (2011) 0.92
Distinct central representations for sensory fibers innervating either the conjunctiva or cornea of the rat. Exp Eye Res (2009) 0.91
Corneal nerve regeneration in neurotrophic keratopathy following autologous plasma therapy. Br J Ophthalmol (2009) 0.90
Docosahexaenoic acid, protectins and dry eye. Curr Opin Clin Nutr Metab Care (2011) 0.90
Beta2-adrenergic receptor signaling mediates corneal epithelial wound repair. Invest Ophthalmol Vis Sci (2008) 0.89
Corneal sensation after myopic and hyperopic LASIK: clinical and confocal microscopic study. Br J Ophthalmol (2005) 0.89
Proteomic analysis of potential keratan sulfate, chondroitin sulfate A, and hyaluronic acid molecular interactions. Invest Ophthalmol Vis Sci (2010) 0.89
Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors. PLoS One (2012) 0.89
Cellular and subbasal nerve alterations in early stage Fuchs' endothelial corneal dystrophy: an in vivo confocal microscopy study. Eye (Lond) (2012) 0.88
The role of O-GlcNAc signaling in the pathogenesis of diabetic retinopathy. Proteomics Clin Appl (2014) 0.88
Chronic dry eye symptoms after LASIK: parallels and lessons to be learned from other persistent post-operative pain disorders. Mol Pain (2015) 0.88
Small fiber neuropathy in Parkinson's disease: A clinical, pathological and corneal confocal microscopy study. Parkinsonism Relat Disord (2015) 0.87
NK cells modulate the inflammatory response to corneal epithelial abrasion and thereby support wound healing. Am J Pathol (2012) 0.87
Removal of the basement membrane enhances corneal wound healing. Exp Eye Res (2011) 0.87
[Neurotrophic keratitis]. Ophthalmologe (2005) 0.87
Early changes in ocular surface and tear inflammatory mediators after small-incision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis. PLoS One (2014) 0.86
The semaphorin 3A inhibitor SM-345431 accelerates peripheral nerve regeneration and sensitivity in a murine corneal transplantation model. PLoS One (2012) 0.86
Nerve growth factor regulates neurolymphatic remodeling during corneal inflammation and resolution. PLoS One (2014) 0.85
Comparison of Standard Versus Wide-Field Composite Images of the Corneal Subbasal Layer by In Vivo Confocal Microscopy. Invest Ophthalmol Vis Sci (2015) 0.84
Expression of pluripotency factors in larval epithelia of the frog Xenopus: evidence for the presence of cornea epithelial stem cells. Dev Biol (2012) 0.84
Collagen XVIII and corneal reinnervation following keratectomy. FEBS Lett (2008) 0.84
The PEDF Neuroprotective Domain Plus DHA Induces Corneal Nerve Regeneration After Experimental Surgery. Invest Ophthalmol Vis Sci (2015) 0.84
Neuropeptide substance P and the immune response. Cell Mol Life Sci (2016) 0.84
Involvement of pigment epithelium-derived factor, docosahexaenoic acid and neuroprotectin D1 in corneal inflammation and nerve integrity after refractive surgery. Prostaglandins Leukot Essent Fatty Acids (2012) 0.83
Hypoxia-induced changes in Ca(2+) mobilization and protein phosphorylation implicated in impaired wound healing. Am J Physiol Cell Physiol (2014) 0.83
In vivo three-dimensional confocal laser scanning microscopy of the epithelial nerve structure in the human cornea. Graefes Arch Clin Exp Ophthalmol (2006) 0.83
Partial denervation of sub-basal axons persists following debridement wounds to the mouse cornea. Lab Invest (2015) 0.83
Cocaine snorting may induce ocular surface damage through corneal sensitivity impairment. Graefes Arch Clin Exp Ophthalmol (2015) 0.82
In Vivo Confocal Microscopy of the Cornea: New Developments in Image Acquisition, Reconstruction, and Analysis Using the HRT-Rostock Corneal Module. Ocul Surf (2015) 0.82
In Vivo Confocal Microscopy of Corneal Nerves in Health and Disease. Ocul Surf (2016) 0.82
[The dry eye. Current concepts on classification, diagnostics, and pathogenesis]. Ophthalmologe (2006) 0.82
Corneal sulfated glycosaminoglycans and their effects on trigeminal nerve growth cone behavior in vitro: roles for ECM in cornea innervation. Invest Ophthalmol Vis Sci (2012) 0.82
Corneal nerve architecture in a donor with unilateral epithelial basement membrane dystrophy. Ophthalmic Res (2013) 0.81
Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins. Invest Ophthalmol Vis Sci (2009) 0.81
The role of corneal afferent neurons in regulating tears under normal and dry eye conditions. Exp Eye Res (2013) 0.81
Trigeminal stereotactic electrolysis induces dry eye in mice. Acta Ophthalmol (2012) 0.81
Silencing of P2Y2 receptor delays Ap4A-corneal re-epithelialization process. Mol Vis (2009) 0.81
Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One (2012) 0.81
Nerve repulsion by the lens and cornea during cornea innervation is dependent on Robo-Slit signaling and diminishes with neuron age. Dev Biol (2012) 0.81
Niche Regulation of Limbal Epithelial Stem Cells: Relationship between Inflammation and Regeneration. Ocul Surf (2016) 0.81
Dendritic cell dysfunction and diabetic sensory neuropathy in the cornea. J Clin Invest (2016) 0.80
The effect of hinge location on corneal sensation and dry eye after LASIK: a systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol (2012) 0.80
Image-guided evaluation and monitoring of treatment response in patients with dry eye disease. Graefes Arch Clin Exp Ophthalmol (2014) 0.80
Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia. J Ophthalmol (2015) 0.80
A Central Role for Sympathetic Nerves in Herpes Stromal Keratitis in Mice. Invest Ophthalmol Vis Sci (2016) 0.80
Neuroanatomy and Neurochemistry of Mouse Cornea. Invest Ophthalmol Vis Sci (2016) 0.80
Understanding Neuropathic Corneal Pain-Gaps and Current Therapeutic Approaches. Semin Ophthalmol (2016) 0.79
The role of fibronectin in corneal wound healing explored by a physician-scientist. Jpn J Ophthalmol (2012) 0.79
In vivo biocompatibility of two PEG/PAA interpenetrating polymer networks as corneal inlays following deep stromal pocket implantation. J Mater Sci Mater Med (2013) 0.79
Loss of corneal sensory nerve fibers in SIV-infected macaques: an alternate approach to investigate HIV-induced PNS damage. Am J Pathol (2014) 0.79
IL-10 function, regulation, and in bacterial keratitis. J Ocul Pharmacol Ther (2014) 0.79
Morphometric features of corneal epithelial basal cells, and their relationship with corneal nerve pathology and clinical factors in patients with type 2 diabetes. J Diabetes Investig (2013) 0.79
Corneal epithelial cells function as surrogate schwann cells for their sensory nerves. Glia (2016) 0.79
Human Tear Serotonin Levels Correlate with Symptoms and Signs of Dry Eye. Ophthalmology (2015) 0.78
Recovery of corneal sensitivity to mechanical and chemical stimulation after laser in situ keratomileusis. J Refract Surg (2004) 1.52
Unilateral photorefractive keratectomy for myopic anisometropia improves contrast sensitivity. Ophthalmology (2004) 1.50
Peripheral hypertrophic subepithelial corneal degeneration - clinical and histopathological features. Acta Ophthalmol (2014) 1.47
Corneal innervation and morphology in primary Sjögren's syndrome. Invest Ophthalmol Vis Sci (2003) 1.41
In vivo confocal microscopy after herpes keratitis. Cornea (2002) 1.38
Short- and long-term safety profile and efficacy of topical bevacizumab (Avastin) eye drops against corneal neovascularization. Graefes Arch Clin Exp Ophthalmol (2009) 1.18
Bevacizumab (Avastin) eye drops inhibit corneal neovascularization. Graefes Arch Clin Exp Ophthalmol (2007) 1.15
Do motor vehicle airbags increase risk of ocular injuries in adults? Ophthalmology (2003) 1.05
Activation of matrix metalloproteinase-8 by membrane type 1-MMP and their expression in human tears after photorefractive keratectomy. Invest Ophthalmol Vis Sci (2003) 1.05
Selective changes in human corneal sensation associated with herpes simplex virus keratitis. Invest Ophthalmol Vis Sci (2010) 1.04
Profiling of WDR36 missense variants in German patients with glaucoma. Invest Ophthalmol Vis Sci (2008) 1.00
Phospholipid transfer protein is present in human tear fluid. Biochemistry (2005) 0.99
In vivo confocal microscopy of Fleck dystrophy and pre-Descemet's membrane corneal dystrophy. Cornea (2003) 0.96
Age-related changes in rat corneal epithelial nerve density. Invest Ophthalmol Vis Sci (2008) 0.95
Expression of bone morphogenetic proteins (BMPs), their receptors, and activins in normal and scarred conjunctiva: role of BMP-6 and activin-A in conjunctival scarring? Exp Eye Res (2006) 0.92
Long-term results of phototherapeutic keratectomy for corneal map-dot-fingerprint dystrophy (Cogan-Guerry). Cornea (2006) 0.89
Excimer laser refractive correction of myopia after episcleral buckling for rhegmatogenous retinal detachment. J Cataract Refract Surg (2007) 0.88
Toxic carriers in pepper sprays may cause corneal erosion. Toxicol Appl Pharmacol (2003) 0.88
Nerve growth factor and corneal wound healing in dogs. Exp Eye Res (2005) 0.87
Seven-year follow-up of LASIK for myopia. J Refract Surg (2009) 0.86
Long-term corneal morphology after PRK by in vivo confocal microscopy. Invest Ophthalmol Vis Sci (2003) 0.85
Interaction of purified tear lipocalin with lipid membranes. Invest Ophthalmol Vis Sci (2005) 0.85
Acinetobacter and Staphylococcus aureus ulcerative keratitis after laser in situ keratomileusis treated with antibiotics and phototherapeutic keratectomy. J Refract Surg (2005) 0.82
Expression and immunolocalization of plasma membrane calcium ATPase isoforms in human corneal epithelium. Mol Vis (2005) 0.82
Corneal sensitivity in diabetic patients subjected to retinal laser photocoagulation. Invest Ophthalmol Vis Sci (2011) 0.81
Relief of migraine following refractive surgery for anisometropia. J Neurol (2005) 0.80
Altered expression of matrix metalloproteinases and their tissue inhibitors as possible contributors to corneal droplet formation in climatic droplet keratopathy. Acta Ophthalmol (2009) 0.79
Metaherpetic corneal disease in a dog associated with partial limbal stem cell deficiency and neurotrophic keratitis. Vet Ophthalmol (2012) 0.78
Keratocyte activation and inflammation in diffuse lamellar keratitis after formation of an epithelial defect. J Cataract Refract Surg (2004) 0.78
Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva. Blood (2002) 0.77
Long-term outcome of central toxic keratopathy after photorefractive keratectomy. Cornea (2011) 0.77
Improvement of visual acuity following refractive surgery for myopia and myopic anisometropia. J Refract Surg (2007) 0.77
Refractive surgery in anisometropic adult patients induce plastic changes in primary visual cortex. Acta Ophthalmol (2011) 0.77
Presence and distribution of L-kynurenine aminotransferases immunoreactivity in human cataractous lenses. Acta Ophthalmol (2013) 0.76
Immunohistochemical identification of kynurenine aminotransferases in corpora amylacea in the human retina and optic nerve. Folia Neuropathol (2007) 0.76
Presence of L-kynurenine aminotransferase III in retinal ganglion cells and corpora amylacea in the human retina and optic nerve. Folia Neuropathol (2011) 0.76
Corneal innervation, corneal mechanical sensitivity, and tear fluid secretion after transscleral contact 670-nm diode laser cyclophotocoagulation. J Glaucoma (2002) 0.75
Photorefractive keratectomy retreatment after LASIK. J Refract Surg (2008) 0.75
Laser refractive correction of myopia in visually impaired patients improves visual acuity. Acta Ophthalmol (2009) 0.75
Neurosarcoidosis mimicking Sjögren's syndrome. Acta Ophthalmol Scand (2004) 0.75
Late traumatic dislocation of laser in situ keratomileusis flaps. J Cataract Refract Surg (2004) 0.75
Peripheral hypertrophic subepithelial corneal degeneration: characterization, treatment and association with human leucocyte antigen genes. Acta Ophthalmol (2013) 0.75
[Eye problem in a building worker]. Duodecim (2003) 0.75
Effects of cyclophotocoagulation with a neodymium:yttrium-aluminum-garnet laser on corneal sensitivity, intraocular pressure, aqueous tear production, and corneal nerve morphology in eyes of dogs. Am J Vet Res (2002) 0.75
Phototherapeutic keratectomy for epithelial irregular astigmatism: an emphasis on map-dot-fingerprint degeneration. J Refract Surg (2007) 0.75
LASIK complication: loss of electricity to the microkeratome during the forward pass. Acta Ophthalmol Scand (2003) 0.75
Long-term follow-up of photorefractive keratectomy for myopia: Comparative study of excimer lasers. J Cataract Refract Surg (2010) 0.75