Published in Invest Ophthalmol Vis Sci on June 01, 2003
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J Cell Biol (2004) 4.16
Proteolytic networks in cancer. Trends Cell Biol (2011) 2.10
Physiology and pathophysiology of matrix metalloproteases. Amino Acids (2010) 1.83
Membrane type 1-matrix metalloproteinase: substrate diversity in pericellular proteolysis. Semin Cell Dev Biol (2007) 1.50
Investigation of the human tear film proteome using multiple proteomic approaches. Mol Vis (2008) 1.45
Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion. J Biol Chem (2009) 1.37
Corneal Regeneration After Photorefractive Keratectomy: A Review. J Optom (2014) 0.95
Dry eye and designer ophthalmics. Optom Vis Sci (2008) 0.84
Tear fluid levels of MMP-8 are elevated in ocular rosacea--treatment effect of oral doxycycline. Graefes Arch Clin Exp Ophthalmol (2006) 0.83
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo. Oncotarget (2016) 0.82
Release of matrix metalloproteinase-8 during physiological trafficking and induced mobilization of human hematopoietic stem cells. Stem Cells Dev (2013) 0.81
Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14. Cancer Med (2014) 0.80
Directed evolution of protease beacons that enable sensitive detection of endogenous MT1-MMP activity in tumor cell lines. Chem Biol (2011) 0.80
MMP regulation of corneal keratocyte motility and mechanics in 3-D collagen matrices. Exp Eye Res (2014) 0.79
The role of matrix metalloproteinase 14 polymorphisms in susceptibility to intervertebral disc degeneration in the Chinese Han population. Arch Med Sci (2015) 0.76
Photorefractive keratectomy: measuring the matrix metalloproteinase activity and chondroitin sulfate concentration in tear fluid. Clin Ophthalmol (2010) 0.76
Effect of the combination of basic fibroblast growth factor and cysteine on corneal epithelial healing after photorefractive keratectomy in patients affected by myopia. Indian J Ophthalmol (2014) 0.75
Matrix Metalloproteinases as Regulators of Periodontal Inflammation. Int J Mol Sci (2017) 0.75
Corneal nerves: structure, contents and function. Exp Eye Res (2003) 4.21
Serum matrix metalloproteinase-8 concentrations are associated with cardiovascular outcome in men. Arterioscler Thromb Vasc Biol (2007) 2.74
The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. J Am Dent Assoc (2011) 2.20
Matrix metalloproteinase-8 (MMP-8) is the major collagenase in human dentin. Arch Oral Biol (2006) 2.09
Gingival crevicular fluid and serum matrix metalloproteinase-8 and tissue inhibitor of matrix metalloproteinase-1 levels in renal transplant patients undergoing different immunosuppressive therapy. J Clin Periodontol (2008) 2.05
Toll-like receptor 9 agonists promote cellular invasion by increasing matrix metalloproteinase activity. Mol Cancer Res (2006) 1.69
Recovery of corneal sensitivity to mechanical and chemical stimulation after laser in situ keratomileusis. J Refract Surg (2004) 1.52
Unilateral photorefractive keratectomy for myopic anisometropia improves contrast sensitivity. Ophthalmology (2004) 1.50
Peripheral hypertrophic subepithelial corneal degeneration - clinical and histopathological features. Acta Ophthalmol (2014) 1.47
Corneal innervation and morphology in primary Sjögren's syndrome. Invest Ophthalmol Vis Sci (2003) 1.41
Emdogain in carcinogenesis: a systematic review of in vitro studies. J Oral Sci (2010) 1.41
In vivo confocal microscopy after herpes keratitis. Cornea (2002) 1.38
Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases. Exp Cell Res (2005) 1.30
Matrix metalloproteinases and their tissue inhibitors in aqueous humor of patients with primary open-angle glaucoma, exfoliation syndrome, and exfoliation glaucoma. J Glaucoma (2005) 1.25
Clinical changes in periodontium during pregnancy and post-partum. J Clin Periodontol (2008) 1.23
Matrix metalloproteinases process the laminin-5 gamma 2-chain and regulate epithelial cell migration. Biochem Biophys Res Commun (2003) 1.23
The effect of subgingival controlled-release delivery of chlorhexidine chip on clinical parameters and matrix metalloproteinase-8 levels in gingival crevicular fluid. J Periodontol (2002) 1.22
Subantimicrobial-dose doxycycline modulates gingival crevicular fluid biomarkers of periodontitis in postmenopausal osteopenic women. J Periodontol (2008) 1.21
Serum MMP-8, -9 and TIMP-1 in sepsis: high serum levels of MMP-8 and TIMP-1 are associated with fatal outcome in a multicentre, prospective cohort study. Hypothetical impact of tetracyclines. Pharmacol Res (2011) 1.21
Salivary biomarkers of oral health: a cross-sectional study. J Clin Periodontol (2012) 1.19
Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9, and -13. J Biol Chem (2003) 1.18
Gingival crevicular fluid collagenase-2 (MMP-8) test stick for chair-side monitoring of periodontitis. J Periodontal Res (2003) 1.16
Matrix metalloproteinases -8, -9 and -12 in smokers and patients with stage 0 COPD. Int J Chron Obstruct Pulmon Dis (2007) 1.15
Salivary biomarkers for detection of systemic diseases. PLoS One (2013) 1.13
Salivary MMP-8, TIMP-1, and ICTP as markers of advanced periodontitis. J Clin Periodontol (2010) 1.12
Airway obstruction correlates with collagenase-2 (MMP-8) expression and activation in bronchial asthma. Lab Invest (2002) 1.11
Use of host- and bacteria-derived salivary markers in detection of periodontitis: a cumulative approach. Dis Markers (2011) 1.08
Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form. Eur J Immunol (2004) 1.07
The microenvironment around total hip replacement prostheses. Clin Orthop Relat Res (2005) 1.07
Metalloproteinase inhibition reduces lung injury and improves survival after cecal ligation and puncture in rats. J Surg Res (2003) 1.06
Do motor vehicle airbags increase risk of ocular injuries in adults? Ophthalmology (2003) 1.05
Tumor-associated trypsinogen-2 (trypsinogen-2) activates procollagenases (MMP-1, -8, -13) and stromelysin-1 (MMP-3) and degrades type I collagen. Biochemistry (2003) 1.04
Selective changes in human corneal sensation associated with herpes simplex virus keratitis. Invest Ophthalmol Vis Sci (2010) 1.04
Salivary biomarkers of bacterial burden, inflammatory response, and tissue destruction in periodontitis. J Clin Periodontol (2014) 1.03
Serum microbial- and host-derived markers of periodontal diseases: a review. Curr Med Chem (2007) 1.02
Inhibition of matrix metalloproteinases by chemically modified tetracyclines in sepsis. Shock (2003) 1.02
Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7). J Biol Chem (2009) 1.01
Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: a mechanistic link between local and systemic inflammation. Pharmacol Res (2011) 1.01
Efficacy of sub-antimicrobial dose doxycycline in post-menopausal women: clinical outcomes. J Clin Periodontol (2007) 1.01
Collagenase-2 (MMP-8) as a point-of-care biomarker in periodontitis and cardiovascular diseases. Therapeutic response to non-antimicrobial properties of tetracyclines. Pharmacol Res (2010) 1.00
Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma. Surg Oncol (2010) 0.99
Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies. Wound Repair Regen (2007) 0.99
Phospholipid transfer protein is present in human tear fluid. Biochemistry (2005) 0.99
Proteolytic roles of matrix metalloproteinase (MMP)-13 during progression of chronic periodontitis: initial evidence for MMP-13/MMP-9 activation cascade. J Clin Periodontol (2009) 0.99
Fluctuating roles of matrix metalloproteinase-9 in oral squamous cell carcinoma. ScientificWorldJournal (2013) 0.97
Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. Infect Immun (2008) 0.97
Human mesenchymal stem cell derived osteoblasts degrade organic bone matrix in vitro by matrix metalloproteinases. Matrix Biol (2005) 0.96
A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth. Cancer Biol Ther (2009) 0.96
In vivo confocal microscopy of Fleck dystrophy and pre-Descemet's membrane corneal dystrophy. Cornea (2003) 0.96
Analysis of matrix metalloproteinases, especially MMP-8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases. Periodontol 2000 (2016) 0.95
Gelatinase A (MMP-2), collagenase-2 (MMP-8), and laminin-5 gamma2-chain expression in murine inflammatory bowel disease (ulcerative colitis). Dig Dis Sci (2003) 0.95
Salivary type I collagen degradation end-products and related matrix metalloproteinases in periodontitis. J Clin Periodontol (2012) 0.94
The effect of adjunctive low-dose doxycycline therapy on clinical parameters and gingival crevicular fluid matrix metalloproteinase-8 levels in chronic periodontitis. J Periodontol (2004) 0.94
Chemically modified tetracycline (CMT-8) and estrogen promote wound healing in ovariectomized rats: effects on matrix metalloproteinase-2, membrane type 1 matrix metalloproteinase, and laminin-5 gamma2-chain. Wound Repair Regen (2002) 0.94
Determination of matrix metalloproteinases in human radicular dentin. J Endod (2009) 0.94
Association of gingival crevicular fluid biomarkers during periodontal maintenance with subsequent progressive periodontitis. J Periodontol (2010) 0.93
Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis. J Clin Periodontol (2014) 0.92
Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell lines. Anticancer Drugs (2002) 0.92
Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment. Biochemistry (2006) 0.91
Effect of decreased loading on the metabolic activity of the mandibular condylar cartilage in the rat. Eur J Orthod (2004) 0.91
Trypsins and their role in carcinoma growth. Exp Cell Res (2006) 0.91
Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study. Acta Odontol Scand (2008) 0.91
Gingival crevicular fluid matrix metalloproteinase (MMP)-7, extracellular MMP inducer, and tissue inhibitor of MMP-1 levels in periodontal disease. J Periodontol (2006) 0.91
Matrix metalloproteinase-7 and matrix metalloproteinase-25 in oral tongue squamous cell carcinoma. Head Neck (2014) 0.90
Factors affecting matrix metalloproteinase-8 levels in the vaginal and cervical fluids in the first and second trimester of pregnancy. Hum Reprod (2009) 0.90
Levels and activation of matrix metalloproteinases in aqueous humor are elevated in uveitis-related secondary glaucoma. J Glaucoma (2006) 0.89
Gingival crevicular fluid MMP-8 and -13 and TIMP-1 levels in patients with rheumatoid arthritis and inflammatory periodontal disease. J Periodontol (2009) 0.89
Tetracyclines and chemically modified tetracycline-3 (CMT-3) modulate cytokine secretion by lipopolysaccharide-stimulated whole blood. Inflammation (2009) 0.89
Excimer laser refractive correction of myopia after episcleral buckling for rhegmatogenous retinal detachment. J Cataract Refract Surg (2007) 0.88
Levels and molecular forms of MMP-7 (matrilysin-1) and MMP-8 (collagenase-2) in diseased human peri-implant sulcular fluid. J Periodontal Res (2003) 0.88
Toxic carriers in pepper sprays may cause corneal erosion. Toxicol Appl Pharmacol (2003) 0.88
Prognostic significance of matrix metalloproteinase-2, -8, -9, and -13 in oral tongue cancer. J Oral Pathol Med (2011) 0.87