PubRank

Sundeep Khosla

Author PubWeight™ 236.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med 2006 7.90
2 Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 2007 6.76
3 Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev 2002 6.38
4 Osteoporosis: now and the future. Lancet 2011 5.81
5 Circulating osteoblast-lineage cells in humans. N Engl J Med 2005 4.19
6 Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res 2004 4.02
7 Fat tissue, aging, and cellular senescence. Aging Cell 2010 3.34
8 Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest 2003 3.09
9 Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev 2007 2.82
10 A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res 2008 2.76
11 Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw. J Rheumatol 2008 2.57
12 Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci U S A 2008 2.39
13 Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. J Clin Endocrinol Metab 2010 2.33
14 For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics. Kidney Int 2009 2.32
15 Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: an update on the changing epidemiology of the disease. J Bone Miner Res 2005 2.15
16 Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res 2007 2.11
17 Fracture risk in type 2 diabetes: update of a population-based study. J Bone Miner Res 2008 2.07
18 Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone. J Clin Endocrinol Metab 2006 2.04
19 The role of the immune system in the pathophysiology of osteoporosis. Immunol Rev 2005 2.03
20 Age-dependence of femoral strength in white women and men. J Bone Miner Res 2010 2.03
21 Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res 2011 2.00
22 Structural determinants of vertebral fracture risk. J Bone Miner Res 2007 1.97
23 Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial. Lancet Oncol 2012 1.94
24 Bisphosphonate associated osteonecrosis of the jaw. J Rheumatol 2009 1.90
25 In vivo assessment of bone quality in postmenopausal women with type 2 diabetes. J Bone Miner Res 2014 1.90
26 Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 2005 1.89
27 Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab 2010 1.87
28 Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. J Cell Biochem 2003 1.76
29 Bone structure at the distal radius during adolescent growth. J Bone Miner Res 2009 1.74
30 The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology 2010 1.74
31 Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop. J Bone Miner Res 2009 1.59
32 Role of circulating osteogenic progenitor cells in calcific aortic stenosis. J Am Coll Cardiol 2012 1.59
33 Mesenchymal stem cells for bone repair and metabolic bone diseases. Mayo Clin Proc 2009 1.59
34 Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT. J Bone Miner Res 2006 1.58
35 Osteocalcin expression by circulating endothelial progenitor cells in patients with coronary atherosclerosis. J Am Coll Cardiol 2008 1.55
36 Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Miner Res 2011 1.53
37 Effects of estrogen with micronized progesterone on cortical and trabecular bone mass and microstructure in recently postmenopausal women. J Clin Endocrinol Metab 2013 1.51
38 Emerging therapeutic opportunities for skeletal restoration. Nat Rev Drug Discov 2011 1.48
39 Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone. J Cell Biochem 2003 1.48
40 Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. Mol Endocrinol 2005 1.48
41 Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women. J Bone Miner Res 2002 1.46
42 Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells. J Bone Miner Res 2003 1.42
43 Fracture risk following bilateral orchiectomy. J Urol 2003 1.41
44 Remodeling and vascular spaces in bone. J Bone Miner Res 2007 1.39
45 Relationship of age to bone microstructure independent of areal bone mineral density. J Bone Miner Res 2012 1.37
46 Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women. J Bone Miner Res 2007 1.35
47 Relation of vertebral deformities to bone density, structure, and strength. J Bone Miner Res 2010 1.32
48 Increasing options for the treatment of osteoporosis. N Engl J Med 2009 1.32
49 Nonoxidative free fatty acid disposal is greater in young women than men. J Clin Endocrinol Metab 2010 1.31
50 Androgen therapy in women: an Endocrine Society Clinical Practice guideline. J Clin Endocrinol Metab 2006 1.30
51 Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology 2003 1.28
52 Fracture risk after bilateral oophorectomy in elderly women. J Bone Miner Res 2003 1.28
53 Contributions of bone density and structure to fracture risk assessment in men and women. Osteoporos Int 2005 1.27
54 Characterization of circulating osteoblast lineage cells in humans. Bone 2007 1.27
55 Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip. Ann Biomed Eng 2010 1.26
56 A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab 2008 1.26
57 Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. FASEB J 2008 1.24
58 Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res 2005 1.24
59 Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways. J Bone Miner Res 2005 1.23
60 Cortical porosity identifies women with osteopenia at increased risk for forearm fractures. J Bone Miner Res 2014 1.21
61 High serum IGFBP-2 is predictive of increased bone turnover in aging men and women. J Bone Miner Res 2007 1.21
62 Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care 2007 1.20
63 Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women. Bone 2011 1.19
64 Female reproductive system and bone. Arch Biochem Biophys 2010 1.19
65 Osteoporosis assessment by whole body region vs. site-specific DXA. Osteoporos Int 2005 1.17
66 Dose-response of estrogen on bone versus the uterus in ovariectomized mice. Eur J Endocrinol 2004 1.16
67 Emerging role of circulating calcifying cells in the bone-vascular axis. Circulation 2012 1.11
68 Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells. Eur Heart J 2010 1.11
69 Placebo-controlled trials in osteoporosis--proceeding with caution. N Engl J Med 2010 1.11
70 Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. Bone 2010 1.10
71 Physiology of bone loss. Radiol Clin North Am 2010 1.09
72 Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res 2010 1.09
73 Fracture risk in monoclonal gammopathy of undetermined significance. J Bone Miner Res 2004 1.08
74 Association of hip strength estimates by finite-element analysis with fractures in women and men. J Bone Miner Res 2011 1.07
75 Skeletal stem/osteoprogenitor cells: current concepts, alternate hypotheses, and relationship to the bone remodeling compartment. J Cell Biochem 2008 1.06
76 Androgens and bone. Steroids 2008 1.05
77 Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action? J Clin Endocrinol Metab 2006 1.04
78 Two years of treatment with dehydroepiandrosterone does not improve insulin secretion, insulin action, or postprandial glucose turnover in elderly men or women. Diabetes 2007 1.04
79 Effects of chronic estrogen treatment on modulating age-related bone loss in female mice. J Bone Miner Res 2010 1.04
80 Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection. Bone 2011 1.04
81 Fracture risk in women with breast cancer: a population-based study. J Bone Miner Res 2012 1.03
82 Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS. Blood 2011 1.02
83 Multicenter precision of cortical and trabecular bone quality measures assessed by high-resolution peripheral quantitative computed tomography. J Bone Miner Res 2013 1.02
84 A potentially deleterious role of IGFBP-2 on bone density in aging men and women. J Bone Miner Res 2004 1.02
85 Estrogen and bone: insights from estrogen-resistant, aromatase-deficient, and normal men. Bone 2008 1.01
86 Trends in fracture incidence: a population-based study over 20 years. J Bone Miner Res 2014 1.01
87 Fracture risk in men with prostate cancer: a population-based study. J Bone Miner Res 2011 1.00
88 What accounts for rib fractures in older adults? J Osteoporos 2011 1.00
89 Estrogen receptor beta isoform-specific induction of transforming growth factor beta-inducible early gene-1 in human osteoblast cells: an essential role for the activation function 1 domain. Mol Endocrinol 2008 1.00
90 Skeletal muscle mass is associated with bone geometry and microstructure and serum insulin-like growth factor binding protein-2 levels in adult women and men. J Bone Miner Res 2012 1.00
91 Relationship of sympathetic activity to bone microstructure, turnover, and plasma osteopontin levels in women. J Clin Endocrinol Metab 2012 0.99
92 Abdominal aortic calcification, BMD, and bone microstructure: a population-based study. J Bone Miner Res 2008 0.99
93 Potential role of pancreatic and enteric hormones in regulating bone turnover. J Bone Miner Res 2005 0.99
94 Subcutaneous administration of insulin-like growth factor (IGF)-II/IGF binding protein-2 complex stimulates bone formation and prevents loss of bone mineral density in a rat model of disuse osteoporosis. Growth Horm IGF Res 2002 0.99
95 Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma. J Bone Miner Res 2014 0.99
96 Regulation of osteoprotegerin production by androgens and anti-androgens in human osteoblastic lineage cells. Eur J Endocrinol 2002 0.98
97 Applications of a New Handheld Reference Point Indentation Instrument Measuring Bone Material Strength. J Med Device 2013 0.98
98 Parathyroid hormone plus alendronate--a combination that does not add up. N Engl J Med 2003 0.98
99 Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women. Bone 2011 0.98
100 Effects of physiological variations in circulating insulin levels on bone turnover in humans. J Clin Endocrinol Metab 2011 0.97
101 Proximal femoral density distribution and structure in relation to age and hip fracture risk in women. J Bone Miner Res 2013 0.97
102 Is vitamin D a determinant of muscle mass and strength? J Bone Miner Res 2011 0.96
103 The oxysterol, 27-hydroxycholesterol, links cholesterol metabolism to bone homeostasis through its actions on the estrogen and liver X receptors. Endocrinology 2011 0.96
104 Effects of testosterone and estradiol on cutaneous vasodilation during local warming in older men. Am J Physiol Endocrinol Metab 2007 0.96
105 Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells. J Cell Biochem 2011 0.96
106 Regulation of bone turnover by sex steroids in men. J Bone Miner Res 2008 0.95
107 Does reduced skeletal loading account for age-related bone loss? J Bone Miner Res 2006 0.95
108 Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics. Mol Endocrinol 2014 0.94
109 Effects of loss of classical estrogen response element signaling on bone in male mice. Endocrinology 2007 0.93
110 Patients with an HbA1c in the prediabetic and diabetic range have higher numbers of circulating cells with osteogenic and endothelial progenitor cell markers. J Clin Endocrinol Metab 2012 0.93
111 Bone growth and turnover in progesterone receptor knockout mice. Endocrinology 2008 0.93
112 Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis. Eur Heart J 2012 0.92
113 Relationship of testosterone and osteocalcin levels during growth. J Bone Miner Res 2011 0.92
114 Male osteoporosis. Endocrinol Metab Clin North Am 2012 0.92
115 Effects of bisphosphonate treatment on circulating osteogenic endothelial progenitor cells in postmenopausal women. Mayo Clin Proc 2012 0.92
116 Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathways. J Biol Chem 2013 0.91
117 Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: roles of AF1 and enhancer elements. J Biol Chem 2006 0.91
118 Fatty acid metabolism in the elderly: effects of dehydroepiandrosterone and testosterone replacement in hormonally deficient men and women. J Clin Endocrinol Metab 2009 0.90
119 TGF-β mediates suppression of adipogenesis by estradiol through connective tissue growth factor induction. Endocrinology 2011 0.90
120 Relationship of adiposity to bone volumetric density and microstructure in men and women across the adult lifespan. Bone 2013 0.89
121 Estrogen inhibits Dlk1/FA1 production: a potential mechanism for estrogen effects on bone turnover. J Bone Miner Res 2011 0.89
122 TGF-β induces Wnt10b in osteoclasts from female mice to enhance coupling to osteoblasts. Endocrinology 2013 0.89
123 Polyphenol-rich cranberry juice has a neutral effect on endothelial function but decreases the fraction of osteocalcin-expressing endothelial progenitor cells. Eur J Nutr 2012 0.89
124 Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow. J Orthop Res 2011 0.89
125 Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts. J Bone Miner Res 2002 0.88
126 Evaluation of a prediction model for long-term fracture risk. J Bone Miner Res 2004 0.88
127 Age-dependent renal cortical microvascular loss in female mice. Am J Physiol Endocrinol Metab 2012 0.88
128 Osteopenia in adults with a history of juvenile rheumatoid arthritis. A population based study. J Rheumatol 2002 0.88
129 Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. J Biol Chem 2009 0.88
130 Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women. J Clin Endocrinol Metab 2013 0.88
131 A distal forearm fracture in childhood is associated with an increased risk for future fragility fractures in adult men, but not women. J Bone Miner Res 2013 0.88
132 Loss of ERE binding activity by estrogen receptor-alpha alters basal and estrogen-stimulated bone-related gene expression by osteoblastic cells. J Cell Biochem 2008 0.87
133 Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling. Endocrinology 2012 0.87
134 Transforming growth factor beta 1 induces CXCL16 and leukemia inhibitory factor expression in osteoclasts to modulate migration of osteoblast progenitors. Bone 2013 0.87
135 Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor alpha on bone. Bone 2011 0.87
136 Circulating osteogenic cells: characterization and relationship to rates of bone loss in postmenopausal women. Bone 2010 0.86
137 Bone microarchitecture in ankylosing spondylitis and the association with bone mineral density, fractures, and syndesmophytes. Arthritis Res Ther 2013 0.86
138 Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts. Growth Horm IGF Res 2003 0.86
139 Serum biomarker profile associated with high bone turnover and BMD in postmenopausal women. J Bone Miner Res 2008 0.86
140 Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency. Osteoporos Int 2003 0.86
141 Leptin-central or peripheral to the regulation of bone metabolism? Endocrinology 2002 0.85
142 Three-dimensional structural analysis of the proximal femur in an age-stratified sample of women. Bone 2013 0.84
143 Estrogen and fracture risk in men. J Bone Miner Res 2008 0.84
144 Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius. J Bone Miner Res 2013 0.83
145 New selective estrogen and androgen receptor modulators. Curr Opin Rheumatol 2009 0.83
146 Examination of nuclear receptor expression in osteoblasts reveals Rorβ as an important regulator of osteogenesis. J Bone Miner Res 2012 0.83
147 A DNA binding mutation in estrogen receptor-α leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts. J Cell Biochem 2012 0.83
148 Use of renal function measurements for assessing fracture risk in postmenopausal women. Mayo Clin Proc 2008 0.82
149 Systemic assessments utilizing saliva: part 2 osteoporosis and use of saliva to measure bone turnover. Int J Prosthodont 2006 0.81
150 Structural patterns of the proximal femur in relation to age and hip fracture risk in women. Bone 2013 0.81
151 Oral bisphosphonate-induced osteonecrosis: risk factors, prediction of risk using serum CTX testing, prevention, and treatment. J Oral Maxillofac Surg 2008 0.81
152 Potential anabolic effects of androgens on bone. Mayo Clin Proc 2004 0.81
153 Better tools for assessing osteoporosis. J Clin Invest 2012 0.80
154 Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity. J Clin Endocrinol Metab 2012 0.80
155 Role of parathyroid hormone in mediating age-related changes in bone resorption in men. Osteoporos Int 2003 0.80
156 Body composition during childhood and adolescence: relations to bone strength and microstructure. J Clin Endocrinol Metab 2014 0.80
157 Effects of estrogen and testosterone on resting energy expenditure in older men. Obesity (Silver Spring) 2010 0.79
158 What do we tell our patients about calcium and vitamin D supplementation? J Clin Endocrinol Metab 2011 0.79
159 Sex- and age-related differences in bone microarchitecture in men relative to women assessed by high-resolution peripheral quantitative computed tomography. J Osteoporos 2012 0.79
160 Is nitroglycerin a novel and inexpensive treatment for osteoporosis? JAMA 2011 0.79
161 Long-term fracture risk among women with proven endometriosis. Fertil Steril 2006 0.78
162 Native osteoprotegerin gene transfer inhibits the development of murine osteolytic bone disease induced by tumor xenografts. Exp Hematol 2004 0.78
163 Potential Extensions of the US FRAX Algorithm. J Osteoporos 2012 0.78
164 Effect of estrogen replacement therapy on parathyroid hormone secretion in elderly postmenopausal women. Menopause 2003 0.78
165 Bisphosphonates and the upper gastrointestinal tract: skeletal gain without visceral pain? Mayo Clin Proc 2002 0.77
166 Assessing the true impact of recurrent fractures on fracture risk. J Bone Miner Res 2009 0.77
167 Androgens, estrogens, and bone turnover in men. J Clin Endocrinol Metab 2003 0.77
168 Modulators of androgen and estrogen receptor activity. Crit Rev Eukaryot Gene Expr 2010 0.76
169 Re: "The 3.6 kb DNA fragment from the rat Col1a1 gene promoter drives the expression of genes in both osteoblast and osteoclast lineage cells" by Boban et al. (Bone 39:1302-1312, 2006). Bone 2007 0.76
170 Mutual enhancement of differentiation of osteoblasts and osteocytes occurs through direct cell-cell contact. J Cell Biochem 2014 0.76
171 A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteoclastogenic mediators. J Clin Endocrinol Metab 2004 0.76
172 Diminished bone strength is observed in adult women and men who sustained a mild trauma distal forearm fracture during childhood. J Bone Miner Res 2014 0.76
173 Osteoporosis update from the 2010 santa fe bone symposium. J Clin Densitom 2011 0.76
174 Longitudinal changes in lumbar bone mineral density distribution may increase the risk of wedge fractures. Clin Biomech (Bristol, Avon) 2012 0.76
175 Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations. PLoS One 2011 0.76
176 Estrogen receptor beta: the antimechanostat? Bone 2005 0.75
177 Identification of Rorβ targets in cultured osteoblasts and in human bone. Biochem Biophys Res Commun 2013 0.75
178 Estrogen therapy and coronary-artery calcification. N Engl J Med 2007 0.75
179 Are the endocrine society's clinical practice guidelines on androgen therapy in women misguided? A commentary-response. J Sex Med 2007 0.75
180 Bone-targeted replacement therapy for hypophosphatasia. J Bone Miner Res 2008 0.75
181 Testosterone: more is not always better. J Clin Endocrinol Metab 2009 0.75
182 High-trauma fractures and bone mineral density. JAMA 2007 0.75
183 Insulin-like growth factor (IGF)-II/IGF-binding proteins in constitutionally tall children. J Clin Endocrinol Metab 2003 0.75
184 Ability of circulating human hematopoietic lineage negative cells to support hematopoiesis. J Cell Biochem 2015 0.75
185 Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice. Nat Med 2017 0.75