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Estrogen therapy and coronary-artery calcification. N Engl J Med (2007) 8.70

HRT and the young at heart. N Engl J Med (2007) 2.07

DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med (2006) 7.90

Bisphosphonate-associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res (2007) 6.76

Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev (2002) 6.38

Osteoporosis: now and the future. Lancet (2011) 5.81

Circulating osteoblast-lineage cells in humans. N Engl J Med (2005) 4.19

Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res (2004) 4.02

Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA (2004) 3.35

Fat tissue, aging, and cellular senescence. Aging Cell (2010) 3.34

Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest (2003) 3.09

Comparison of the effect of denosumab and alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a randomized, blinded, phase 3 trial. J Bone Miner Res (2009) 2.99

Receptor activator of nuclear factor kappaB ligand and osteoprotegerin regulation of bone remodeling in health and disease. Endocr Rev (2007) 2.82

A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men. J Bone Miner Res (2008) 2.76

Canadian consensus practice guidelines for bisphosphonate associated osteonecrosis of the jaw. J Rheumatol (2008) 2.57

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis. J Clin Invest (2013) 2.48

The leukocyte integrin antagonist Del-1 inhibits IL-17-mediated inflammatory bone loss. Nat Immunol (2012) 2.48

Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. Proc Natl Acad Sci U S A (2008) 2.39

Effects of suppression of follicle-stimulating hormone secretion on bone resorption markers in postmenopausal women. J Clin Endocrinol Metab (2010) 2.33

For estimating creatinine clearance measuring muscle mass gives better results than those based on demographics. Kidney Int (2009) 2.32

Measurements of plasma methoxytyramine, normetanephrine, and metanephrine as discriminators of different hereditary forms of pheochromocytoma. Clin Chem (2011) 2.24

Incidence of primary hyperparathyroidism in Rochester, Minnesota, 1993-2001: an update on the changing epidemiology of the disease. J Bone Miner Res (2005) 2.15

Contribution of in vivo structural measurements and load/strength ratios to the determination of forearm fracture risk in postmenopausal women. J Bone Miner Res (2007) 2.11

Fracture risk in type 2 diabetes: update of a population-based study. J Bone Miner Res (2008) 2.07

Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone. J Clin Endocrinol Metab (2006) 2.04

The role of the immune system in the pathophysiology of osteoporosis. Immunol Rev (2005) 2.03

Age-dependence of femoral strength in white women and men. J Bone Miner Res (2010) 2.03

Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res (2011) 2.00

Structural determinants of vertebral fracture risk. J Bone Miner Res (2007) 1.97

Bone density and structure in healthy postmenopausal women treated with exemestane for the primary prevention of breast cancer: a nested substudy of the MAP.3 randomised controlled trial. Lancet Oncol (2012) 1.94

Bisphosphonate associated osteonecrosis of the jaw. J Rheumatol (2009) 1.90

In vivo assessment of bone quality in postmenopausal women with type 2 diabetes. J Bone Miner Res (2014) 1.90

Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun (2005) 1.89

Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab (2010) 1.87

Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. J Cell Biochem (2003) 1.76

Bone structure at the distal radius during adolescent growth. J Bone Miner Res (2009) 1.74

The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis. Endocrinology (2010) 1.74

Bone, sweet bone--osteoporotic fractures in diabetes mellitus. Nat Rev Endocrinol (2012) 1.73

Targeting bone remodeling for the treatment of osteoporosis: summary of the proceedings of an ASBMR workshop. J Bone Miner Res (2009) 1.59

Role of circulating osteogenic progenitor cells in calcific aortic stenosis. J Am Coll Cardiol (2012) 1.59

Mesenchymal stem cells for bone repair and metabolic bone diseases. Mayo Clin Proc (2009) 1.59

Age- and sex-specific differences in the factor of risk for vertebral fracture: a population-based study using QCT. J Bone Miner Res (2006) 1.58

Selective glucocorticoid receptor modulation maintains bone mineral density in mice. J Bone Miner Res (2012) 1.58

Osteocalcin expression by circulating endothelial progenitor cells in patients with coronary atherosclerosis. J Am Coll Cardiol (2008) 1.55

Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Miner Res (2011) 1.53

RANK ligand and osteoprotegerin: paracrine regulators of bone metabolism and vascular function. Arterioscler Thromb Vasc Biol (2002) 1.52

Effects of estrogen with micronized progesterone on cortical and trabecular bone mass and microstructure in recently postmenopausal women. J Clin Endocrinol Metab (2013) 1.51

Emerging therapeutic opportunities for skeletal restoration. Nat Rev Drug Discov (2011) 1.48

Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. Mol Endocrinol (2005) 1.48

Mediators of the biphasic responses of bone to intermittent and continuously administered parathyroid hormone. J Cell Biochem (2003) 1.48

Increased osteoprotegerin serum levels in men with coronary artery disease. J Clin Endocrinol Metab (2003) 1.46

Role of low levels of endogenous estrogen in regulation of bone resorption in late postmenopausal women. J Bone Miner Res (2002) 1.46

Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells. J Bone Miner Res (2003) 1.42

Fracture risk following bilateral orchiectomy. J Urol (2003) 1.41

Remodeling and vascular spaces in bone. J Bone Miner Res (2007) 1.39

Relationship of age to bone microstructure independent of areal bone mineral density. J Bone Miner Res (2012) 1.37

Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Mönckeberg's sclerosis and atherosclerosis. J Clin Endocrinol Metab (2004) 1.35

Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women. J Bone Miner Res (2007) 1.35

Bisphosphonates pamidronate and zoledronic acid stimulate osteoprotegerin production by primary human osteoblasts. Biochem Biophys Res Commun (2002) 1.35

Relation of vertebral deformities to bone density, structure, and strength. J Bone Miner Res (2010) 1.32

Increasing options for the treatment of osteoporosis. N Engl J Med (2009) 1.32

Nonoxidative free fatty acid disposal is greater in young women than men. J Clin Endocrinol Metab (2010) 1.31

Androgen therapy in women: an Endocrine Society Clinical Practice guideline. J Clin Endocrinol Metab (2006) 1.30

Gorham-Stout disease--stabilization during bisphosphonate treatment. J Bone Miner Res (2004) 1.29

Mineral surface in calcified plaque is like that of bone: further evidence for regulated mineralization. Arterioscler Thromb Vasc Biol (2008) 1.29

Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology (2003) 1.28

Fracture risk after bilateral oophorectomy in elderly women. J Bone Miner Res (2003) 1.28

Prevention of glucocorticoid-induced bone loss in mice by inhibition of RANKL. Arthritis Rheum (2009) 1.27

Contributions of bone density and structure to fracture risk assessment in men and women. Osteoporos Int (2005) 1.27

Characterization of circulating osteoblast lineage cells in humans. Bone (2007) 1.27

Robust QCT/FEA models of proximal femur stiffness and fracture load during a sideways fall on the hip. Ann Biomed Eng (2010) 1.26

A bone structural basis for fracture risk in diabetes. J Clin Endocrinol Metab (2008) 1.26

Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements. FASEB J (2008) 1.24

Population-based analysis of the relationship of whole bone strength indices and fall-related loads to age- and sex-specific patterns of hip and wrist fractures. J Bone Miner Res (2005) 1.24

Skeletal effects of estrogen are mediated by opposing actions of classical and nonclassical estrogen receptor pathways. J Bone Miner Res (2005) 1.23

Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice. Am J Pathol (2009) 1.23

Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood (2003) 1.22

Cortical porosity identifies women with osteopenia at increased risk for forearm fractures. J Bone Miner Res (2014) 1.21

High serum IGFBP-2 is predictive of increased bone turnover in aging men and women. J Bone Miner Res (2007) 1.21

Effect of 2 years of testosterone replacement on insulin secretion, insulin action, glucose effectiveness, hepatic insulin clearance, and postprandial glucose turnover in elderly men. Diabetes Care (2007) 1.20

Effects of estrogen on osteoprogenitor cells and cytokines/bone-regulatory factors in postmenopausal women. Bone (2011) 1.19

Female reproductive system and bone. Arch Biochem Biophys (2010) 1.19

Osteoporosis assessment by whole body region vs. site-specific DXA. Osteoporos Int (2005) 1.17

Dose-response of estrogen on bone versus the uterus in ovariectomized mice. Eur J Endocrinol (2004) 1.16

miR-125b regulates calcification of vascular smooth muscle cells. Am J Pathol (2011) 1.15

Expression of receptor activator of nuclear factor kappaB ligand on bone marrow plasma cells correlates with osteolytic bone disease in patients with multiple myeloma. Clin Cancer Res (2003) 1.14

Emerging role of circulating calcifying cells in the bone-vascular axis. Circulation (2012) 1.11

The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis. Nephrol Dial Transplant (2008) 1.11

Coronary endothelial dysfunction in humans is associated with coronary retention of osteogenic endothelial progenitor cells. Eur Heart J (2010) 1.11

Placebo-controlled trials in osteoporosis--proceeding with caution. N Engl J Med (2010) 1.11

Human embryonic stem cell-derived CD34+ cells function as MSC progenitor cells. Bone (2010) 1.10

Physiology of bone loss. Radiol Clin North Am (2010) 1.09

Low serum levels of soluble RANK ligand are associated with the presence of coronary artery disease in men. Circulation (2003) 1.09

TRAIL stimulates proliferation of vascular smooth muscle cells via activation of NF-kappaB and induction of insulin-like growth factor-1 receptor. J Biol Chem (2008) 1.09

Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res (2010) 1.09

WNT5A is induced by inflammatory mediators in bone marrow stromal cells and regulates cytokine and chemokine production. J Bone Miner Res (2012) 1.08

Fracture risk in monoclonal gammopathy of undetermined significance. J Bone Miner Res (2004) 1.08

Association of hip strength estimates by finite-element analysis with fractures in women and men. J Bone Miner Res (2011) 1.07