Published in Rev Physiol Biochem Pharmacol on April 16, 2003
Proline cis-trans isomerization controls autoinhibition of a signaling protein. Mol Cell (2007) 2.44
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90. EMBO J (2006) 1.89
The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability. Mol Cell Biol (2007) 1.19
Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin. EMBO J (2005) 1.17
Key factors in mTOR regulation. Cell Mol Life Sci (2009) 1.08
Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline. PLoS One (2008) 1.07
Chaperone domains convert prolyl isomerases into generic catalysts of protein folding. Proc Natl Acad Sci U S A (2009) 1.02
Prolyl isomerase Pin1 in cancer. Cell Res (2014) 1.01
Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1. J Med Chem (2010) 0.97
N-linked sugar-regulated protein folding and quality control in the ER. Semin Cell Dev Biol (2014) 0.97
Role of cyclophilin A from brains of prion-infected mice in stimulation of cytokine release by microglia and astroglia in vitro. J Biol Chem (2011) 0.95
Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation. J Biol Chem (2008) 0.94
Solution structure of the FK506-binding domain of human FKBP38. J Biomol NMR (2006) 0.94
Complete determination of the Pin1 catalytic domain thermodynamic cycle by NMR lineshape analysis. J Biomol NMR (2011) 0.94
The emerging role of large immunophilin FK506 binding protein 51 in cancer. Curr Med Chem (2011) 0.94
Isoform-specific inhibition of cyclophilins. Biochemistry (2009) 0.92
Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB. J Neurooncol (2010) 0.92
A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins. Angew Chem Int Ed Engl (2010) 0.89
Activation of colicin M by the FkpA prolyl cis-trans isomerase/chaperone. J Biol Chem (2010) 0.88
Structure-based classification of 45 FK506-binding proteins. Proteins (2008) 0.88
FKBP38 protects Bcl-2 from caspase-dependent degradation. J Biol Chem (2010) 0.86
Surface expression of Bcl-2 in chronic lymphocytic leukemia and other B-cell leukemias and lymphomas without a breakpoint t(14;18). Mol Med (2008) 0.86
A critical step for JNK activation: isomerization by the prolyl isomerase Pin1. Cell Death Differ (2011) 0.85
A remote prolyl isomerization controls domain assembly via a hydrogen bonding network. Proc Natl Acad Sci U S A (2009) 0.85
Cyclophilin A (CypA) interacts with NF-κB subunit, p65/RelA, and contributes to NF-κB activation signaling. PLoS One (2014) 0.84
Depletion of cyclophilins B and C leads to dysregulation of endoplasmic reticulum redox homeostasis. J Biol Chem (2014) 0.84
FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma. Nucleic Acids Res (2015) 0.83
Molecular and biochemical characterization of the parvulin-type PPIases in Lotus japonicus. Plant Physiol (2009) 0.82
Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol Dis (2015) 0.82
The novel calcineurin inhibitor CN585 has potent immunosuppressive properties in stimulated human T cells. J Biol Chem (2009) 0.81
Novel role for cyclophilin A in regulation of chondrogenic commitment and endochondral ossification. Mol Cell Biol (2015) 0.80
ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair. Front Oncol (2014) 0.80
Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.79
Hepatitis C virus comes for dinner: How the hepatitis C virus interferes with autophagy. World J Gastroenterol (2015) 0.79
Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis. J Biol Chem (2014) 0.78
A Selective, Cell-Permeable Nonphosphorylated Bicyclic Peptidyl Inhibitor against Peptidyl-Prolyl Isomerase Pin1. J Med Chem (2015) 0.78
Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax. Eukaryot Cell (2013) 0.78
In silico analysis of the cyclophilin repertoire of apicomplexan parasites. Parasit Vectors (2009) 0.78
Cis-trans peptide variations in structurally similar proteins. Amino Acids (2012) 0.78
The peptidyl-prolyl isomerase activity of SlyD is not required for maturation of Escherichia coli hydrogenase. J Bacteriol (2007) 0.77
Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90. Biosci Rep (2015) 0.77
Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.77
Identification of HIV inhibitors guided by free energy perturbation calculations. Curr Pharm Des (2012) 0.77
Initiation of phage infection by partial unfolding and prolyl isomerization. J Biol Chem (2013) 0.76
Cyclosporin A impairs the secretion and activity of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat). J Biol Chem (2012) 0.75
Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function. MBio (2016) 0.75