Published in Trends Microbiol on April 01, 2003
Kaposi's sarcoma-associated herpesvirus modulates microtubule dynamics via RhoA-GTP-diaphanous 2 signaling and utilizes the dynein motors to deliver its DNA to the nucleus. J Virol (2005) 1.64
Cytotoxic necrotizing factor-Y boosts Yersinia effector translocation by activating Rac protein. J Biol Chem (2013) 0.81
Response from Emmanuel Lemichez: A new turn in Rho GTPase activation by Escherichia coli cytotoxic necrotizing factors. Trends Microbiol (2003) 0.75
Inhibition of Rho A activity causes pemphigus skin blistering. J Cell Biol (2006) 1.45
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes. Mol Biol Cell (2011) 1.39
The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA. J Biol Chem (2004) 1.36
Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering. Science (2010) 1.36
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J (2011) 1.36
Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway. J Cell Sci (2010) 1.31
Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni. Cell Microbiol (2007) 1.24
The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. J Pharmacol Exp Ther (2002) 1.20
Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac. Infect Immun (2002) 1.18
Auto-ADP-ribosylation of Pseudomonas aeruginosa ExoS. J Biol Chem (2002) 1.16
The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2. Traffic (2009) 1.14
The cytotoxic necrotizing factors from Yersinia pseudotuberculosis and from Escherichia coli bind to different cellular receptors but take the same route to the cytosol. Infect Immun (2007) 1.03
Small rho GTPases regulate antigen presentation in dendritic cells. J Immunol (2005) 1.00
Targeting of the actin cytoskeleton by insecticidal toxins from Photorhabdus luminescens. Naunyn Schmiedebergs Arch Pharmacol (2010) 0.93
Isotype-specific degradation of Rac activated by the cytotoxic necrotizing factor 1. J Biol Chem (2004) 0.92
The C terminus of YopT is crucial for activity and the N terminus is crucial for substrate binding. Infect Immun (2003) 0.90
Cytotoxic Necrotizing Factors (CNFs)-A Growing Toxin Family. Toxins (Basel) (2011) 0.89
Inhibition of cytokinesis by Clostridium difficile toxin B and cytotoxic necrotizing factors--reinforcing the critical role of RhoA in cytokinesis. Cell Motil Cytoskeleton (2009) 0.88
A new member of a growing toxin family--Escherichia coli cytotoxic necrotizing factor 3 (CNF3). Toxicon (2009) 0.85
Listeria monocytogenes induced Rac1-dependent signal transduction in endothelial cells. Biochem Pharmacol (2006) 0.85
Cleavage of Escherichia coli cytotoxic necrotizing factor 1 is required for full biologic activity. Infect Immun (2009) 0.85
Change in substrate specificity of cytotoxic necrotizing factor unmasks proteasome-independent down-regulation of constitutively active RhoA. J Biol Chem (2007) 0.83
Exchange of a single amino acid switches the substrate properties of RhoA and RhoD toward glucosylating and transglutaminating toxins. J Biol Chem (2006) 0.81
The polybasic region of Rho GTPases defines the cleavage by Yersinia enterocolitica outer protein T (YopT). Protein Sci (2008) 0.81
Pasteurella multocida toxin prevents osteoblast differentiation by transactivation of the MAP-kinase cascade via the Gα(q/11)--p63RhoGEF--RhoA axis. PLoS Pathog (2013) 0.81
Endoproteolytic processing of RhoA by Rce1 is required for the cleavage of RhoA by Yersinia enterocolitica outer protein T. Infect Immun (2006) 0.81
Increased Cell-Matrix Adhesion upon Constitutive Activation of Rho Proteins by Cytotoxic Necrotizing Factors from E. Coli and Y. Pseudotuberculosis. J Signal Transduct (2012) 0.80
Toxin-induced RhoA activity mediates CCL1-triggered signal transducers and activators of transcription protein signaling. J Biol Chem (2012) 0.80
RhoA activation by CNFy restores cell-cell adhesion in kindlin-2-deficient keratinocytes. J Pathol (2014) 0.78
Pleiotropic role of Rac in mast cell activation revealed by a cell permeable Bordetella dermonecrotic fusion toxin. Cell Signal (2010) 0.78
Influence of Birch Bark Triterpenes on Keratinocytes and Fibroblasts from Diabetic and Nondiabetic Donors. J Nat Prod (2016) 0.77
Pituitary adenylyl cyclase-activating polypeptide 38 reduces astroglial proliferation by inhibiting the GTPase RhoA. J Biol Chem (2005) 0.77
Photorhabdus luminescens toxins TccC3 and TccC5: insecticidal ADP-ribosyltransferases that modify threonine and glutamine. Curr Top Microbiol Immunol (2015) 0.77
Activation of RhoA,B,C by Yersinia Cytotoxic Necrotizing Factor (CNFy) induces apoptosis in LNCaP prostate cancer cells. Toxins (Basel) (2013) 0.76
EhRho1, a RhoA-like GTPase of Entamoeba histolytica, is modified by clostridial glucosylating cytotoxins. Appl Environ Microbiol (2006) 0.75
How to analyze bacterial toxins targeting Rho GTPases. Methods Mol Biol (2012) 0.75
Diverse effects of RacV12 on cell transformation by Raf: partial inhibition of morphological transformation versus deregulation of cell cycle control. Biochim Biophys Acta (2002) 0.75
Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1. Int J Biochem Cell Biol (2013) 0.75
Cytotoxic Necrotizing Factors: Rho-Activating Toxins from Escherichia coli. Ecosal Plus (2004) 0.75
The actin and Rho-modifying toxins PTC3 and PTC5 of Photorhabdus luminescens: enzyme characterization and induction of MAL/SRF-dependent transcription. Cell Microbiol (2014) 0.75
The priority program Signal Pathways to the Cytoskeleton and Bacterial Pathogenesis (SPP1150). Eur J Cell Biol (2011) 0.75