Published in J Cell Sci on May 11, 2010
Caveolae as plasma membrane sensors, protectors and organizers. Nat Rev Mol Cell Biol (2013) 2.98
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion. Am J Physiol Endocrinol Metab (2011) 1.50
The diverse roles of Rac signaling in tumorigenesis. Cell Cycle (2011) 1.38
Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase. J Biol Chem (2012) 1.17
Rab5 activation promotes focal adhesion disassembly, migration and invasiveness in tumor cells. J Cell Sci (2013) 1.07
Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions? Dev Cell (2012) 1.04
Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget (2012) 1.04
The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion. PLoS One (2012) 1.03
Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis. PLoS Biol (2014) 1.02
CD81 regulates cell migration through its association with Rac GTPase. Mol Biol Cell (2012) 0.94
Rho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular trafficking. Small GTPases (2014) 0.93
Rho GTPase regulation by miRNAs and covalent modifications. Trends Cell Biol (2012) 0.90
The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization. J Biol Chem (2012) 0.90
RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac. J Cell Biochem (2011) 0.90
Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure. J Cell Sci (2014) 0.88
Rac-ing to the plasma membrane: the long and complex work commute of Rac1 during cell signaling. Small GTPases (2012) 0.88
Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts. J Cell Sci (2012) 0.87
Rho GTPases, oxidation, and cell redox control. Small GTPases (2014) 0.87
A model for phospho-caveolin-1-driven turnover of focal adhesions. Cell Adh Migr (2011) 0.86
Newcastle disease virus interaction in targeted therapy against proliferation and invasion pathways of glioblastoma multiforme. Biomed Res Int (2014) 0.86
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion. J Cell Biol (2015) 0.85
Caveolin-1 regulates genomic action of the glucocorticoid receptor in neural stem cells. Mol Cell Biol (2014) 0.84
The GAP activity of type III effector YopE triggers killing of Yersinia in macrophages. PLoS Pathog (2014) 0.84
The Rac1 hypervariable region in targeting and signaling: a tail of many stories. Small GTPases (2013) 0.83
The Rho family member RhoE interacts with Skp2 and is degraded at the proteasome during cell cycle progression. J Biol Chem (2013) 0.83
Redox regulation of Rac1 by thiol oxidation. Free Radic Biol Med (2014) 0.83
Ubiquitylation of active Rac1 by the E3 ubiquitin-ligase HACE1. Small GTPases (2012) 0.82
IAPs as E3 ligases of Rac1: shaping the move. Small GTPases (2012) 0.79
The human minor histocompatibility antigen 1 is a RhoGAP. PLoS One (2013) 0.79
Prometastatic NEDD9 Regulates Individual Cell Migration via Caveolin-1-Dependent Trafficking of Integrins. Mol Cancer Res (2014) 0.79
Protein tyrosine phosphatase PTP1B in cell adhesion and migration. Cell Adh Migr (2013) 0.78
An Impaired Respiratory Electron Chain Triggers Down-regulation of the Energy Metabolism and De-ubiquitination of Solute Carrier Amino Acid Transporters. Mol Cell Proteomics (2016) 0.77
A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosis. Eur J Hum Genet (2015) 0.75
Caveolin-1 regulates corneal wound healing by modulating Kir4.1 activity. Am J Physiol Cell Physiol (2016) 0.75
Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. Mol Cell Proteomics (2015) 0.75
Characterization of Novel Molecular Mechanisms Favoring Rac1 Membrane Translocation. PLoS One (2016) 0.75
Caveolin-1 regulates Rac1 activation and rat pulmonary microvascular endothelial hyperpermeability induced by TNF-α. PLoS One (2013) 0.75
Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein Trafficking. J Biol Chem (2015) 0.75
Caveolin-1 regulates osteoclast differentiation by suppressing cFms degradation. Exp Mol Med (2015) 0.75
Nucleophosmin1 is a negative regulator of the small GTPase Rac1. PLoS One (2013) 0.75
The phospho-caveolin-1 scaffolding domain dampens force fluctuations in focal adhesions and promotes cancer cell migration. Mol Biol Cell (2017) 0.75
Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nat Rev Mol Cell Biol (2010) 2.72
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix. J Cell Biol (2006) 2.58
VCAM-1-mediated Rac signaling controls endothelial cell-cell contacts and leukocyte transmigration. Am J Physiol Cell Physiol (2003) 2.37
Glycoproteomics based on tandem mass spectrometry of glycopeptides. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 1.99
Calcium signaling regulates translocation and activation of Rac. J Biol Chem (2003) 1.94
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell (2010) 1.94
Domain-wide regulation of gene expression in the human genome. Genome Res (2007) 1.86
Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells. J Cell Sci (2002) 1.72
IgG glycosylation analysis. Proteomics (2009) 1.71
Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells. Proc Natl Acad Sci U S A (2009) 1.66
Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study. Arthritis Res Ther (2009) 1.63
P-selectin glycoprotein ligand-1 is expressed on endothelial cells and mediates monocyte adhesion to activated endothelium. Arterioscler Thromb Vasc Biol (2007) 1.63
Detecting minimal residual disease in neuroblastoma: the superiority of a panel of real-time quantitative PCR markers. Clin Chem (2009) 1.62
Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J Leukoc Biol (2008) 1.57
Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. J Immunol (2008) 1.56
Glycosylation profiling of immunoglobulin G (IgG) subclasses from human serum. Proteomics (2007) 1.53
Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid. Arthritis Rheum (2010) 1.53
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. PLoS Genet (2013) 1.52
An evaluation of urine-CCA strip test and fingerprick blood SEA-ELISA for detection of urinary schistosomiasis in schoolchildren in Zanzibar. Acta Trop (2009) 1.52
Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly. J Cell Sci (2003) 1.52
Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits. J Cell Biol (2002) 1.47
The C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity. J Biol Chem (2003) 1.45
Inhibition of Rho A activity causes pemphigus skin blistering. J Cell Biol (2006) 1.45
Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation. J Biol Chem (2005) 1.45
A new turn in Rho GTPase activation by Escherichia coli cytotoxic necrotizing factors. Trends Microbiol (2003) 1.40
High capacity capillary electrophoresis-electrospray ionization mass spectrometry: coupling a porous sheathless interface with transient-isotachophoresis. Anal Chem (2010) 1.39
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes. Mol Biol Cell (2011) 1.39
Lack of complex N-glycans on HIV-1 envelope glycoproteins preserves protein conformation and entry function. Virology (2010) 1.36
The Yersinia pseudotuberculosis cytotoxic necrotizing factor (CNFY) selectively activates RhoA. J Biol Chem (2004) 1.36
Photorhabdus luminescens toxins ADP-ribosylate actin and RhoA to force actin clustering. Science (2010) 1.36
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J (2011) 1.36
Electron transfer dissociation of N-glycopeptides: loss of the entire N-glycosylated asparagine side chain. Rapid Commun Mass Spectrom (2007) 1.36
LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation. EMBO J (2011) 1.34
Rac1-induced cell migration requires membrane recruitment of the nuclear oncogene SET. EMBO J (2007) 1.31
Signaling in leukocyte transendothelial migration. Arterioscler Thromb Vasc Biol (2004) 1.28
High-throughput profiling of protein N-glycosylation by MALDI-TOF-MS employing linkage-specific sialic acid esterification. Anal Chem (2014) 1.27
Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS. Biochim Biophys Acta (2012) 1.27
Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of beta1 and beta2 integrins. J Leukoc Biol (2006) 1.26
The detection limits for estimates of infection intensity in schistosomiasis mansoni established by a study in non-human primates. Int J Parasitol (2006) 1.26
Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection. J Allergy Clin Immunol (2007) 1.24
Structural glycomics using hydrophilic interaction chromatography (HILIC) with mass spectrometry. Mass Spectrom Rev (2009) 1.24
Cotton HILIC SPE microtips for microscale purification and enrichment of glycans and glycopeptides. Anal Chem (2011) 1.24
Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni. Cell Microbiol (2007) 1.24
Rac1 mediates collapse of microvilli on chemokine-activated T lymphocytes. J Immunol (2004) 1.23
The F-BAR domain protein PACSIN2 associates with Rac1 and regulates cell spreading and migration. J Cell Sci (2011) 1.23
The role of ubiquitylation and degradation in RhoGTPase signalling. J Cell Sci (2010) 1.22
LacdiNAc-glycans constitute a parasite pattern for galectin-3-mediated immune recognition. J Immunol (2004) 1.22
A robust dry reagent lateral flow assay for diagnosis of active schistosomiasis by detection of Schistosoma circulating anodic antigen. Exp Parasitol (2013) 1.21
Annexin A2 phosphorylation mediates cell scattering and branching morphogenesis via cofilin Activation. Mol Cell Biol (2007) 1.21
Fc specific IgG glycosylation profiling by robust nano-reverse phase HPLC-MS using a sheath-flow ESI sprayer interface. J Proteomics (2011) 1.21
Protein glycosylation analysis by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.20
Fc-glycosylation of IgG1 is modulated by B-cell stimuli. Mol Cell Proteomics (2011) 1.20
The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. J Pharmacol Exp Ther (2002) 1.20
Glycoproteomic analysis of antibodies. Mol Cell Proteomics (2013) 1.19
Proteasomal degradation of cytotoxic necrotizing factor 1-activated rac. Infect Immun (2002) 1.18
Oligosaccharide analysis by graphitized carbon liquid chromatography-mass spectrometry. Anal Bioanal Chem (2009) 1.18
PKA and Epac1 regulate endothelial integrity and migration through parallel and independent pathways. Eur J Cell Biol (2008) 1.17
Leukocyte-endothelium interaction promotes SDF-1-dependent polarization of CXCR4. J Biol Chem (2003) 1.17
Retinoic acid induces blood-brain barrier development. J Neurosci (2013) 1.17
High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides. J Proteome Res (2013) 1.16
Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation. J Proteome Res (2013) 1.16
Auto-ADP-ribosylation of Pseudomonas aeruginosa ExoS. J Biol Chem (2002) 1.16
Epac1-Rap1 signaling regulates monocyte adhesion and chemotaxis. J Leukoc Biol (2006) 1.16
The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2. Traffic (2009) 1.14
Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus. Mol Biol Cell (2003) 1.14
Mass spectrometry of proton adducts of fucosylated N-glycans: fucose transfer between antennae gives rise to misleading fragments. Rapid Commun Mass Spectrom (2006) 1.14
Hydrophilic interaction chromatography-based high-throughput sample preparation method for N-glycan analysis from total human plasma glycoproteins. Anal Chem (2008) 1.13
General microarray technique for immobilization and screening of natural glycans. Anal Chem (2007) 1.13
Migration of human hematopoietic progenitor cells across bone marrow endothelium is regulated by vascular endothelial cadherin. J Immunol (2002) 1.13
Continuous translocation of Rac2 and the NADPH oxidase component p67(phox) during phagocytosis. J Biol Chem (2003) 1.12
Normal-phase nanoscale liquid chromatography-mass spectrometry of underivatized oligosaccharides at low-femtomole sensitivity. Anal Chem (2004) 1.12
Imaging mass spectrometry statistical analysis. J Proteomics (2012) 1.11
Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies. Arterioscler Thromb Vasc Biol (2003) 1.11
N-glycosylation of colorectal cancer tissues: a liquid chromatography and mass spectrometry-based investigation. Mol Cell Proteomics (2012) 1.11
Peptide and protein imaging mass spectrometry in cancer research. J Proteomics (2010) 1.10
Scientific workflow management in proteomics. Mol Cell Proteomics (2012) 1.10
cAMP signaling in leukocyte transendothelial migration. Arterioscler Thromb Vasc Biol (2007) 1.09
Filamin B mediates ICAM-1-driven leukocyte transendothelial migration. J Biol Chem (2008) 1.09
Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity. J Pathol (2010) 1.08
Mass spectrometric glycan rearrangements. Mass Spectrom Rev (2011) 1.07
The major secreted protein Msp1/p75 is O-glycosylated in Lactobacillus rhamnosus GG. Microb Cell Fact (2012) 1.06
Decreased levels of bisecting GlcNAc glycoforms of IgG are associated with human longevity. PLoS One (2010) 1.05