Published in Invest Ophthalmol Vis Sci on May 01, 2003
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. Mol Vis (2009) 2.08
Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am J Pathol (2008) 1.61
Role of NADPH oxidase in retinal vascular inflammation. Invest Ophthalmol Vis Sci (2008) 1.57
Bacterial endophthalmitis: therapeutic challenges and host-pathogen interactions. Prog Retin Eye Res (2007) 1.49
Adalimumab in the therapy of uveitis in childhood. Br J Ophthalmol (2006) 1.47
The A2b adenosine receptor protects against vascular injury. Proc Natl Acad Sci U S A (2008) 1.39
Diabetic complications and dysregulated innate immunity. Front Biosci (2008) 1.28
Systemic administration of HMG-CoA reductase inhibitor protects the blood-retinal barrier and ameliorates retinal inflammation in type 2 diabetes. Exp Eye Res (2009) 1.23
Adalimumab (Humira™): a promising monoclonal anti-tumor necrosis factor alpha in ophthalmology. Int Ophthalmol (2011) 1.15
Retracted Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. Mol Vis (2008) 1.14
Arginase activity mediates retinal inflammation in endotoxin-induced uveitis. Am J Pathol (2009) 1.12
Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation. J Biol Chem (2008) 1.11
Dual involvement of caspase-4 in inflammatory and ER stress-induced apoptotic responses in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2009) 1.07
MCP-1 deficiency delays regression of pathologic retinal neovascularization in a model of ischemic retinopathy. Invest Ophthalmol Vis Sci (2008) 1.05
The expression of cytokines in the aqueous humor and serum during endotoxin-induced uveitis in C3H/HeN mice. Mol Vis (2010) 1.02
Interplay between innate and adaptive immunity in the development of non-infectious uveitis. Prog Retin Eye Res (2011) 0.98
Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases. Mediators Inflamm (2015) 0.96
Lentiviral-vector-mediated expression of murine IL-1 receptor antagonist or IL-10 reduces the severity of endotoxin-induced uveitis. Gene Ther (2008) 0.96
Bacterial endophthalmitis in the age of outpatient intravitreal therapies and cataract surgeries: host-microbe interactions in intraocular infection. Prog Retin Eye Res (2012) 0.96
NAD(P)H oxidase-dependent regulation of CCL2 production during retinal inflammation. Invest Ophthalmol Vis Sci (2009) 0.92
Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes. Diabetologia (2012) 0.92
Angiotensin-converting enzyme 2 (ACE2) activator diminazene aceturate ameliorates endotoxin-induced uveitis in mice. Invest Ophthalmol Vis Sci (2014) 0.92
Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13. Am J Pathol (2007) 0.92
Beta-adrenergic receptor agonist decreases VEGF levels through altered eNOS and PKC signaling in diabetic retina. Growth Factors (2015) 0.90
Pharmacokinetics and safety of intravitreally delivered etanercept. Graefes Arch Clin Exp Ophthalmol (2004) 0.89
Preventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats. Invest Ophthalmol Vis Sci (2011) 0.87
Anti-inflammatory effects of cannabinoid CB(2) receptor activation in endotoxin-induced uveitis. Br J Pharmacol (2014) 0.86
Green tea extract treatment alleviates ocular inflammation in a rat model of endotoxin-induced uveitis. PLoS One (2014) 0.84
Adalimumab (humira™) in ophthalmology: a review of the literature. Middle East Afr J Ophthalmol (2010) 0.84
Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy. PLoS One (2012) 0.83
Endoplasmic reticulum stress and inflammation: mechanisms and implications in diabetic retinopathy. J Ocul Biol Dis Infor (2012) 0.83
Regulated expression of caspase-12 gene in human retinal pigment epithelial cells suggests its immunomodulating role. Invest Ophthalmol Vis Sci (2008) 0.83
Effect of N-acetylcysteine on lipopolysaccharide-induced uveitis in rats. Jpn J Ophthalmol (2007) 0.82
TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media. BMC Immunol (2011) 0.81
In vivo evaluation of ocular inflammatory responses in experimental diabetes. Br J Ophthalmol (2005) 0.81
Effects of a thrombomodulin-derived peptide on monocyte adhesion and intercellular adhesion molecule-1 expression in lipopolysaccharide-induced endothelial cells. Mol Vis (2013) 0.79
Impacts of nanomedicines in ocular pharmacotherapy. Bioimpacts (2011) 0.79
Calcium channel blocker nilvadipine, but not diltiazem, inhibits ocular inflammation in endotoxin-induced uveitis. Jpn J Ophthalmol (2010) 0.78
Mammalian telomeric DNA suppresses endotoxin-induced uveitis. J Biol Chem (2010) 0.78
Inhibition of ocular aldose reductase by a new benzofuroxane derivative ameliorates rat endotoxic uveitis. Mediators Inflamm (2014) 0.77
Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats. Br J Pharmacol (2008) 0.76
Bacillus anthracis genomic DNA enhances lethal toxin-induced cytotoxicity through TNF-α production. BMC Microbiol (2014) 0.76
Effect of the Toll-like receptor 4 antagonist eritoran on retinochoroidal inflammatory damage in a rat model of endotoxin-induced inflammation. Mediators Inflamm (2014) 0.76
MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment. Int J Mol Sci (2016) 0.75
Botulinum toxin-induced acute anterior uveitis in a patient with Behçet's disease under infliximab treatment: a case report. J Med Case Rep (2017) 0.75
Epac1 agonist decreased inflammatory proteins in retinal endothelial cells, and loss of Epac1 increased inflammatory proteins in the retinal vasculature of mice. Mol Vis (2017) 0.75
Systemic administration of an anti-tumor necrosis factor-alpha monoclonal antibody protects against endotoxin-induced uveitis in rats. Indian J Ophthalmol (2016) 0.75
Phenol-soluble modulin α4 mediates Staphylococcus aureus-associated vascular leakage by stimulating heparin-binding protein release from neutrophils. Sci Rep (2016) 0.75
The Effectiveness of Pre- and Postoperative Infliximab in Controlling Behçet's Disease Posterior Uveitis in Patients Undergoing Vitrectomy: A Preliminary Study. J Ophthalmol (2017) 0.75
Sodium thiosulphate attenuates brain inflammation induced by systemic lipopolysaccharide administration in C57BL/6J mice. Inflammopharmacology (2017) 0.75
Infliximab exerts a dose-dependent effect on retinal safety in the albino rabbit. Doc Ophthalmol (2017) 0.75
Nitric oxide potentiates TNF-α-induced neurotoxicity through suppression of NF-κB. Cell Mol Neurobiol (2011) 0.75
Intravitreal aflibercept (VEGF trap-eye) in wet age-related macular degeneration. Ophthalmology (2012) 8.29
A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J (2004) 5.33
Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc Natl Acad Sci U S A (2002) 4.33
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood (2002) 3.73
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci U S A (2003) 3.30
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors. Cancer Cell (2004) 3.25
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood (2002) 3.01
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression. FASEB J (2002) 2.90
Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogene (2002) 2.66
Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation. Clin Cancer Res (2006) 2.40
The SECURE study: long-term safety of ranibizumab 0.5 mg in neovascular age-related macular degeneration. Ophthalmology (2012) 2.30
Antimyeloma activity of heat shock protein-90 inhibition. Blood (2005) 2.24
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am J Pathol (2002) 2.20
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. Mol Vis (2009) 2.08
Spectral-domain optical coherence tomography in subjects over 60 years of age, and its implications for designing clinical trials. Br J Ophthalmol (2012) 2.03
Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells. Blood (2002) 1.97
Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF. J Clin Invest (2002) 1.95
Molecular sequelae of histone deacetylase inhibition in human malignant B cells. Blood (2003) 1.92
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications. Blood (2002) 1.92
Non-responders to bevacizumab (Avastin) therapy of choroidal neovascular lesions. Br J Ophthalmol (2007) 1.88
Suppression of diabetic retinopathy with angiopoietin-1. Am J Pathol (2002) 1.68
Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes. FASEB J (2002) 1.63
Indocyanine-green-assisted internal limiting membrane peeling in macular hole surgery--a follow-up study. Graefes Arch Clin Exp Ophthalmol (2002) 1.47
Retinal stimuli can be restored after autologous transplant of retinal pigment epithelium and choroid in pigment epithelium tears. Acta Ophthalmol (2011) 1.45
Neodymium:YAG laser capsulotomy in vitrectomized pseudophakic eyes with persistent endotamponade. J Cataract Refract Surg (2003) 1.42
Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy. Am J Pathol (2004) 1.39
Autologous translocation of the choroid and retinal pigment epithelium in age-related macular degeneration. Am J Ophthalmol (2006) 1.36
Fundus near infrared fluorescence correlates with fundus near infrared reflectance. Invest Ophthalmol Vis Sci (2006) 1.29
Visual outcome and complications after posterior iris-claw aphakic intraocular lens implantation. J Cataract Refract Surg (2012) 1.29
Optical coherence tomography in parkinsonian syndromes. PLoS One (2012) 1.24
Inhibition of TNF-alpha reduces laser-induced choroidal neovascularization. Exp Eye Res (2006) 1.24
Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro. J Clin Endocrinol Metab (2006) 1.24
Sustained inhibition of corneal neovascularization by genetic ablation of CCR5. Invest Ophthalmol Vis Sci (2003) 1.22
Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology (2011) 1.20
Retinal pigment epithelium and endothelial cell interaction causes retinal pigment epithelial barrier dysfunction via a soluble VEGF-dependent mechanism. Exp Eye Res (2003) 1.19
Outcome of combined penetrating keratoplasty with vitreoretinal surgery for management of severe ocular injuries. Retina (2003) 1.19
Combined penetrating keratoplasty and vitreoretinal surgery with silicone oil: a 1-year follow-up. Graefes Arch Clin Exp Ophthalmol (2002) 1.17
VEGF-dependent conjunctivalization of the corneal surface. Invest Ophthalmol Vis Sci (2003) 1.17
Bevacizumab (Avastin) treatment in patients with retinal angiomatous proliferation. Graefes Arch Clin Exp Ophthalmol (2007) 1.13
Long-term effects of ranibizumab treatment delay in neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2012) 1.11
Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature. Invest Ophthalmol Vis Sci (2002) 1.11
Genotype-dependent sensitivity of uveal melanoma cell lines to inhibition of B-Raf, MEK, and Akt kinases: rationale for personalized therapy. Invest Ophthalmol Vis Sci (2011) 1.07
Novel histone deacetylase inhibitors in the treatment of thyroid cancer. Clin Cancer Res (2005) 1.06
Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice. Invest Ophthalmol Vis Sci (2006) 1.05
Inhibition of corneal neovascularization by genetic ablation of CCR2. Cornea (2003) 1.05
β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment. EMBO Mol Med (2012) 1.05
Targeting BRAFV600E in thyroid carcinoma: therapeutic implications. Mol Cancer Ther (2007) 1.04
Latanoprost stimulates secretion of matrix metalloproteinases in tenon fibroblasts both in vitro and in vivo. Invest Ophthalmol Vis Sci (2003) 1.04
Clinical outcomes after switching treatment from intravitreal ranibizumab to aflibercept in neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol (2013) 1.03
[Treatment of Acute Central Retinal Artery Occlusion (CRAO) by Hyperbaric Oxygenation Therapy (HBO)--Pilot study with 21 patients]. Klin Monbl Augenheilkd (2002) 1.03
Serum concentrations of vascular endothelial growth factor in an infant treated with ranibizumab for retinopathy of prematurity. Acta Ophthalmol (2012) 1.02
Effect of a capsular tension ring on refractive outcomes in eyes with high myopia. J Cataract Refract Surg (2010) 1.01
Cumulative effect of risk alleles in CFH, ARMS2, and VEGFA on the response to ranibizumab treatment in age-related macular degeneration. Ophthalmology (2012) 1.01
Aqueous flare is increased in patients with clinically significant cystoid macular oedema after cataract surgery. Br J Ophthalmol (2013) 1.01
Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma: mutational and functional analysis. J Clin Endocrinol Metab (2006) 1.00
Differential role of tumor necrosis factor (TNF)-alpha receptors in the development of choroidal neovascularization. Invest Ophthalmol Vis Sci (2010) 0.99
Autologous translocation of the choroid and retinal pigment epithelium in patients with geographic atrophy. Ophthalmology (2007) 0.99
Subjective perception versus objective outcome after intravitreal ranibizumab for exudative AMD. Graefes Arch Clin Exp Ophthalmol (2011) 0.98
Angiopoietin modulation of vascular endothelial growth factor: Effects on retinal endothelial cell permeability. Cytokine (2007) 0.98
Influence of ocular volume and lens status on pharmacokinetics and duration of action of intravitreal vascular endothelial growth factor inhibitors. Retina (2015) 0.98
Heavy silicone oil versus standard silicone oil in as vitreous tamponade in inferior PVR (HSO Study): interim analysis. Acta Ophthalmol (2011) 0.98
Visual outcome of patients with macular edema after pars plana vitrectomy and indocyanine green-assisted peeling of the internal limiting membrane. Graefes Arch Clin Exp Ophthalmol (2004) 0.97
Evaluation of serum lipid concentrations and genetic variants at high-density lipoprotein metabolism loci and TIMP3 in age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 0.97
iStent inject in phakic open angle glaucoma. Graefes Arch Clin Exp Ophthalmol (2015) 0.97
Immunohistochemical localization of complement regulatory proteins in the human retina. Histol Histopathol (2012) 0.96
Grading of Age-Related Macular Degeneration: Comparison between Color Fundus Photography, Fluorescein Angiography, and Spectral Domain Optical Coherence Tomography. J Ophthalmol (2013) 0.96
Fixation stability and macular light sensitivity in patients with diabetic maculopathy: a microperimetric study with a scanning laser ophthalmoscope. Ophthalmologica (2005) 0.96
Profibrotic cytokines in aqueous humour correlate with aqueous flare in patients with rhegmatogenous retinal detachment. Br J Ophthalmol (2013) 0.96
Comparison of intact and denuded amniotic membrane as a substrate for cell-suspension culture of human limbal epithelial cells. Graefes Arch Clin Exp Ophthalmol (2006) 0.95
Overexpression of FasL in retinal pigment epithelial cells reduces choroidal neovascularization. FASEB J (2006) 0.95
Visual outcomes and complications following posterior iris-claw aphakic intraocular lens implantation combined with penetrating keratoplasty. Graefes Arch Clin Exp Ophthalmol (2012) 0.93
Varied expression of functionally important genes of RPE and choroid in the macula and in the periphery of normal human eyes. Graefes Arch Clin Exp Ophthalmol (2006) 0.93
Vascular endothelial growth factor in patients with exudative age-related macular degeneration treated with ranibizumab. Ophthalmology (2012) 0.93
Course of intraocular pressure after vitreoretinal surgery: is early postoperative intraocular pressure elevation predictable? Retina (2011) 0.92
Intraoperative Optical Coherence Tomography Enables Noncontact Imaging During Canaloplasty. J Glaucoma (2016) 0.92
Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy. Invest Ophthalmol Vis Sci (2009) 0.91
Increased leukocyte-endothelial interactions in syndecan-1-deficient mice involve heparan sulfate-dependent and -independent steps. Curr Eye Res (2005) 0.91
Angiostatin inhibits and regresses corneal neovascularization. Arch Ophthalmol (2002) 0.91
Rebound, applanation, and dynamic contour tonometry in pathologic corneas. Cornea (2013) 0.91