PubRank

Reynold A Panettieri

Author PubWeight™ 148.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). J Biol Chem 2002 4.19
2 Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma. J Appl Physiol (1985) 2012 2.31
3 Airway smooth muscle cells enhance C3a-induced mast cell degranulation following cell-cell contact. FASEB J 2005 2.13
4 Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. Am J Respir Cell Mol Biol 2003 1.91
5 Asthma outcomes: biomarkers. J Allergy Clin Immunol 2012 1.88
6 Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway. J Clin Invest 2009 1.83
7 Attitudes of physicians toward objective measures of airway function in asthma. Am J Med 2003 1.80
8 CD38/cyclic ADP-ribose-mediated Ca2+ signaling contributes to airway smooth muscle hyper-responsiveness. FASEB J 2003 1.63
9 PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2002 1.57
10 Roles of cysteinyl leukotrienes in airway inflammation, smooth muscle function, and remodeling. J Allergy Clin Immunol 2003 1.52
11 TGF-beta potentiates airway smooth muscle responsiveness to bradykinin. Am J Physiol Lung Cell Mol Physiol 2005 1.51
12 Aclidinium bromide abrogates allergen-induced hyperresponsiveness and reduces eosinophilia in murine model of airway inflammation. Eur J Pharmacol 2010 1.47
13 Modulation of calcium signaling by interleukin-13 in human airway smooth muscle: role of CD38/cyclic adenosine diphosphate ribose pathway. Am J Respir Cell Mol Biol 2004 1.43
14 GABAA receptors are expressed and facilitate relaxation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2008 1.43
15 Steroids completely reverse albuterol-induced beta(2)-adrenergic receptor tolerance in human small airways. J Allergy Clin Immunol 2008 1.41
16 TAS2R activation promotes airway smooth muscle relaxation despite β(2)-adrenergic receptor tachyphylaxis. Am J Physiol Lung Cell Mol Physiol 2012 1.40
17 Placebo response in asthma: a robust and objective phenomenon. J Allergy Clin Immunol 2007 1.38
18 Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. Am J Respir Cell Mol Biol 2002 1.37
19 Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. FASEB J 2003 1.36
20 IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol 2003 1.35
21 IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK. Am J Physiol Lung Cell Mol Physiol 2002 1.34
22 Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms. Biochemistry 2005 1.23
23 Receptors and pathways mediating the effects of prostaglandin E2 on airway tone. Am J Physiol Lung Cell Mol Physiol 2002 1.23
24 Airway smooth muscle: a modulator of airway remodeling in asthma. J Allergy Clin Immunol 2005 1.23
25 Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth. Biochemistry 2005 1.23
26 CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2005 1.23
27 Airway smooth muscle as an immunomodulatory cell. Pulm Pharmacol Ther 2008 1.20
28 Regulation of TNF-alpha- and IFN-gamma-induced CXCL10 expression: participation of the airway smooth muscle in the pulmonary inflammatory response in chronic obstructive pulmonary disease. FASEB J 2003 1.19
29 IL-13 and IL-4 promote TARC release in human airway smooth muscle cells: role of IL-4 receptor genotype. Am J Physiol Lung Cell Mol Physiol 2003 1.17
30 TNF-[alpha] modulates murine tracheal rings responsiveness to G-protein-coupled receptor agonists and KCl. J Appl Physiol (1985) 2003 1.16
31 Functional expression of the GABAB receptor in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2006 1.14
32 Impact of pulmonary artery pressure on exercise function in severe COPD. Chest 2009 1.14
33 Tumor necrosis factor alpha modulates airway smooth muscle function via the autocrine action of interferon beta. J Biol Chem 2003 1.13
34 Modulation of calcium homeostasis as a mechanism for altering smooth muscle responsiveness in asthma. Curr Opin Allergy Clin Immunol 2002 1.11
35 Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet 2012 1.09
36 Anti-mitogenic effects of β-agonists and PGE2 on airway smooth muscle are PKA dependent. FASEB J 2010 1.09
37 Synthetic responses in airway smooth muscle. J Allergy Clin Immunol 2004 1.09
38 TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation. Am J Physiol Lung Cell Mol Physiol 2009 1.08
39 Angiogenesis is induced by airway smooth muscle strain. Am J Physiol Lung Cell Mol Physiol 2007 1.08
40 Inhibition of human airway smooth muscle cell proliferation by beta 2-adrenergic receptors and cAMP is PKA independent: evidence for EPAC involvement. Am J Physiol Lung Cell Mol Physiol 2007 1.07
41 Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11). FASEB J 2006 1.06
42 miR-140-3p regulation of TNF-α-induced CD38 expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2012 1.06
43 Noncontractile functions of airway smooth muscle cells in asthma. Annu Rev Physiol 2009 1.06
44 Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway. Mol Pharmacol 2004 1.05
45 Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization. Respir Res 2003 1.05
46 MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. FASEB J 2014 1.05
47 Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS. Am J Physiol Lung Cell Mol Physiol 2005 1.04
48 Raf-1, actin dynamics, and abelson tyrosine kinase in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2012 1.04
49 Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids. FASEB J 2006 1.03
50 Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs. FASEB J 2005 1.02
51 Chronic obstructive pulmonary disease and inhaled steroids alter surfactant protein D (SP-D) levels: a cross-sectional study. Respir Res 2008 1.02
52 Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complex. J Biol Chem 2011 1.02
53 Essential role of IFNbeta and CD38 in TNFalpha-induced airway smooth muscle hyper-responsiveness. Immunobiology 2008 1.01
54 Oncostatin M causes eotaxin-1 release from airway smooth muscle: synergy with IL-4 and IL-13. J Allergy Clin Immunol 2005 1.01
55 Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB J 2004 1.01
56 Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production. J Immunol 2009 1.00
57 Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells. Nat Protoc 2006 1.00
58 Is airway remodeling clinically relevant in asthma? Am J Med 2003 0.99
59 Social stress and asthma: the role of corticosteroid insensitivity. J Allergy Clin Immunol 2010 0.98
60 Airway epithelium stimulates smooth muscle proliferation. Am J Respir Cell Mol Biol 2009 0.98
61 Asthma in the elderly: the role of exhaled nitric oxide measurements. Respir Med 2013 0.98
62 Bronchial hyperresponsiveness: insights into new signaling molecules. Curr Opin Pharmacol 2004 0.98
63 Mast cell chymase modifies cell-matrix interactions and inhibits mitogen-induced proliferation of human airway smooth muscle cells. J Immunol 2002 0.97
64 Hyperpolarized 3He MRI in asthma measurements of regional ventilation following allergic sensitization and challenge in mice--preliminary results. Acad Radiol 2005 0.97
65 Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. Am J Respir Cell Mol Biol 2009 0.97
66 Airway smooth muscle cell hyperplasia: a therapeutic target in airway remodeling in asthma? Prog Cell Cycle Res 2003 0.97
67 Airway smooth muscle in asthma: just a target for bronchodilation? Clin Chest Med 2012 0.96
68 Activation of p38 MAP-kinase and caldesmon phosphorylation are essential for urokinase-induced human smooth muscle cell migration. Biol Chem 2002 0.96
69 C-027 inhibits IgE-mediated passive sensitization bronchoconstriction and acts as a histamine and serotonin antagonist in human airways. Allergy Asthma Proc 2011 0.95
70 Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13. Respir Res 2010 0.95
71 Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-alpha and dexamethasone. Respir Res 2008 0.95
72 Oncostatin M causes VEGF release from human airway smooth muscle: synergy with IL-1beta. Am J Physiol Lung Cell Mol Physiol 2005 0.95
73 Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis. Mol Pharmacol 2009 0.95
74 Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration. Am J Physiol Lung Cell Mol Physiol 2002 0.95
75 Differential induction of CD38 expression by TNF-{alpha} in asthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2010 0.94
76 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. PLoS One 2010 0.94
77 Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors. Mol Pharmacol 2007 0.94
78 Glucocorticoid regulation of CD38 expression in human airway smooth muscle cells: role of dual specificity phosphatase 1. Am J Physiol Lung Cell Mol Physiol 2008 0.93
79 Interleukin-13 and interleukin-4 induce vascular endothelial growth factor release from airway smooth muscle cells: role of vascular endothelial growth factor genotype. Am J Respir Cell Mol Biol 2005 0.92
80 Trichostatin A abrogates airway constriction, but not inflammation, in murine and human asthma models. Am J Respir Cell Mol Biol 2012 0.92
81 Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2008 0.91
82 Bradykinin induces interleukin-6 production in human airway smooth muscle cells: modulation by Th2 cytokines and dexamethasone. Am J Respir Cell Mol Biol 2003 0.91
83 Airway smooth muscle: contraction and beyond. Int J Biochem Cell Biol 2003 0.91
84 Ozone modulates IL-6 secretion in human airway epithelial and smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2009 0.91
85 β2-adrenergic receptor agonists modulate human airway smooth muscle cell migration via vasodilator-stimulated phosphoprotein. Am J Respir Cell Mol Biol 2012 0.90
86 Cross-talk between tuberin, calmodulin, and estrogen signaling pathways. FASEB J 2005 0.90
87 The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respir Res 2005 0.89
88 Airway smooth muscle as a regulator of immune responses and bronchomotor tone. Clin Chest Med 2006 0.89
89 Anaphylatoxin C3a receptors in asthma. Respir Res 2005 0.89
90 Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells. Am J Respir Cell Mol Biol 2010 0.88
91 Interleukin-9 influences chemokine release in airway smooth muscle: role of ERK. Am J Physiol Lung Cell Mol Physiol 2003 0.88
92 Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle. Am J Respir Cell Mol Biol 2011 0.88
93 Regulator of G protein signaling 2 is a key modulator of airway hyperresponsiveness. J Allergy Clin Immunol 2012 0.87
94 Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells. Can J Physiol Pharmacol 2005 0.87
95 Inhibition of myristoylated alanine-rich C kinase substrate (MARCKS) protein inhibits ozone-induced airway neutrophilia and inflammation. Exp Lung Res 2010 0.87
96 The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer. Mol Biol Cell 2012 0.87
97 A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle. FASEB J 2012 0.87
98 Induction of ANGPTL4 expression in human airway smooth muscle cells by PMA through activation of PKC and MAPK pathways. Exp Cell Res 2009 0.87
99 Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2005 0.87
100 Functional expression of γ-amino butyric acid transporter 2 in human and guinea pig airway epithelium and smooth muscle. Am J Respir Cell Mol Biol 2010 0.87
101 Does airway smooth muscle express an inflammatory phenotype in asthma? Br J Pharmacol 2011 0.86
102 IFN-gamma inhibits human airway smooth muscle cell proliferation by modulating the E2F-1/Rb pathway. Am J Physiol Lung Cell Mol Physiol 2003 0.86
103 Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. Mol Pharmacol 2007 0.86
104 Is airway smooth muscle the "missing link" modulating airway inflammation in asthma? Chest 2008 0.86
105 Airway smooth muscle and immunomodulation in acute exacerbations of airway disease. Immunol Rev 2011 0.85
106 Bitter taste receptor function in asthmatic and nonasthmatic human airway smooth muscle cells. Am J Respir Cell Mol Biol 2014 0.84
107 Regulation of inflammation by airway smooth muscle. Curr Allergy Asthma Rep 2008 0.84
108 An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. PLoS One 2012 0.84
109 Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle. FASEB J 2013 0.84
110 Interferons modulate mitogen-induced protein synthesis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2010 0.84
111 Drug development for severe asthma: what are the metrics? Pharmacol Ther 2012 0.84
112 Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases. Am J Respir Cell Mol Biol 2012 0.83
113 Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness. J Biol Chem 2011 0.83
114 Expression and muscarinic receptor coupling of Lyn kinase in cultured human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2005 0.82
115 Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma. Am J Respir Cell Mol Biol 2012 0.82
116 Phosphodiesterases regulate airway smooth muscle function in health and disease. Curr Top Dev Biol 2007 0.82
117 MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells. Respir Res 2014 0.82
118 CD38 and airway hyper-responsiveness: studies on human airway smooth muscle cells and mouse models. Can J Physiol Pharmacol 2014 0.82
119 TNF-α regulation of CD38 expression in human airway smooth muscle: role of MAP kinases and NF-κB. Adv Exp Med Biol 2011 0.81
120 A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation. FASEB J 2012 0.81
121 Profile of aclidinium bromide in the treatment of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2011 0.81
122 Deficiency of melanoma differentiation-associated protein 5 results in exacerbated chronic postviral lung inflammation. Am J Respir Crit Care Med 2014 0.81
123 A pilot study of the feasibility of confocal endomicroscopy for examination of the human airway. J Bronchology Interv Pulmonol 2010 0.80
124 Polycyclic aromatic hydrocarbons impair function of β2-adrenergic receptors in airway epithelial and smooth muscle cells. Am J Respir Cell Mol Biol 2011 0.80
125 Nebulized dehydroepiandrosterone-3-sulfate improves asthma control in the moderate-to-severe asthma results of a 6-week, randomized, double-blind, placebo-controlled study. Allergy Asthma Proc 2011 0.80
126 Effect of IL-1beta on CRE-dependent gene expression in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2002 0.80
127 Raf-1 kinase mediates adenylyl cyclase sensitization by TNF-alpha in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 2007 0.79
128 The dopamine D(2) receptor is expressed and sensitizes adenylyl cyclase activity in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2011 0.79
129 In vitro and in vivo pharmacological profile of PL-3994, a novel cyclic peptide (Hept-cyclo(Cys-His-Phe-d-Ala-Gly-Arg-d-Nle-Asp-Arg-Ile-Ser-Cys)-Tyr-[Arg mimetic]-NH(2)) natriuretic peptide receptor-A agonist that is resistant to neutral endopeptidase and acts as a bronchodilator. Pulm Pharmacol Ther 2012 0.79
130 Targeting airway smooth muscle in airways diseases: an old concept with new twists. Expert Rev Respir Med 2011 0.79
131 G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells. J Biomed Sci 2005 0.78
132 An Official American Thoracic Society Research Statement: Current Challenges Facing Research and Therapeutic Advances in Airway Remodeling. Am J Respir Crit Care Med 2017 0.78
133 Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness. J Pharmacol Exp Ther 2010 0.78
134 Correction: Unconventional Gas and Oil Drilling Is Associated with Increased Hospital Utilization Rates. PLoS One 2015 0.78
135 Response to C3a, mast cells, and asthma. FASEB J 2006 0.77
136 Irreversible airway obstruction in asthma: what we lose, we lose early. Allergy Asthma Proc 2014 0.77
137 Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype. J Allergy (Cairo) 2012 0.77
138 Transgenic smooth muscle expression of the human CysLT1 receptor induces enhanced responsiveness of murine airways to leukotriene D4. Am J Physiol Lung Cell Mol Physiol 2004 0.76
139 Epithelium-generated neuropeptide Y induces smooth muscle contraction to promote airway hyperresponsiveness. J Clin Invest 2016 0.76
140 Functional capacity, health status, and inflammatory biomarker profile in a cohort of patients with chronic obstructive pulmonary disease. J Cardiopulm Rehabil Prev 2015 0.76
141 Regulation of phospholipase A2 by interleulin-1 in human airway smooth muscle. Chest 2003 0.76
142 Last Word on Point: Alterations in airway smooth muscle phenotype do cause airway hyperresponsiveness in asthma. J Appl Physiol (1985) 2012 0.76
143 DHEA-S inhibits human neutrophil and human airway smooth muscle migration. Biochim Biophys Acta 2012 0.76
144 Erratum. Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity. Eur Respir J 2015 0.75
145 Effect of dexamethasone on beta2-adrenergic desensitization in airway smooth muscle: role of the ARG19 polymorphism. Chest 2003 0.75
146 In the clinic. Asthma. Ann Intern Med 2007 0.75