Published in Proc Nutr Soc on February 01, 2003
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res (2013) 2.67
Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers. J Nutr (2009) 1.94
The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat Commun (2014) 1.44
Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health? Neurosci Lett (2016) 0.91
Altered gut microbial energy and metabolism in children with non-alcoholic fatty liver disease. FEMS Microbiol Ecol (2014) 0.89
Gut bacteria alteration in obese people and its relationship with gene polymorphism. World J Gastroenterol (2011) 0.87
Tools for the tract: understanding the functionality of the gastrointestinal tract. Therap Adv Gastroenterol (2009) 0.86
Characterization of the GATC regulatory network in E. coli. BMC Genomics (2004) 0.79
Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects. Br J Clin Pharmacol (2016) 0.76
Low abundance of colonic butyrate-producing bacteria in HIV infection is associated with microbial translocation and immune activation. AIDS (2017) 0.75
Removal of ovarian hormones affects the ageing process of acetate metabolism. N Am J Med Sci (2009) 0.75
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet (2003) 11.67
A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med (2015) 11.05
Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. N Engl J Med (2015) 5.59
Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9. Arterioscler Thromb Vasc Biol (2004) 2.37
Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells. J Lipid Res (2005) 1.79
Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1c. J Biol Chem (2006) 1.60
Novel mutations of the PCSK9 gene cause variable phenotype of autosomal dominant hypercholesterolemia. Hum Mutat (2005) 1.54
Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody. Circ Cardiovasc Genet (2015) 1.50
The rate of protein digestion affects protein gain differently during aging in humans. J Physiol (2003) 1.28
Residual macrovascular risk in 2013: what have we learned? Cardiovasc Diabetol (2014) 1.20
Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. J Biol Chem (2008) 1.16
Efficacy and safety of alirocumab in patients with heterozygous familial hypercholesterolemia not adequately controlled with current lipid-lowering therapy: design and rationale of the ODYSSEY FH studies. Cardiovasc Drugs Ther (2014) 1.15
Intronic mutations outside of Alu-repeat-rich domains of the LDL receptor gene are a cause of familial hypercholesterolemia. Hum Genet (2002) 1.14
Proprotein convertase subtilisin kexin type 9 null mice are protected from postprandial triglyceridemia. Arterioscler Thromb Vasc Biol (2009) 1.12
Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes. FEBS Lett (2008) 1.03
High protein intake reduces intrahepatocellular lipid deposition in humans. Am J Clin Nutr (2009) 1.01
PCSK9 and LDL cholesterol: unravelling the target to design the bullet. Trends Biochem Sci (2008) 1.00
Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor. Endocrinology (2006) 1.00
Fasting plasma chenodeoxycholic acid and cholic acid concentrations are inversely correlated with insulin sensitivity in adults. Nutr Metab (Lond) (2011) 0.97
Weight loss in obese dogs: evaluation of a high-protein, low-carbohydrate diet. J Nutr (2002) 0.96
Carotid and femoral atherosclerotic plaques show different morphology. Atherosclerosis (2011) 0.96
Dietary threonine restriction specifically reduces intestinal mucin synthesis in rats. J Nutr (2005) 0.95
PCSK9 dominant negative mutant results in increased LDL catabolic rate and familial hypobetalipoproteinemia. Arterioscler Thromb Vasc Biol (2009) 0.95
Effects of green tea on insulin sensitivity, lipid profile and expression of PPARalpha and PPARgamma and their target genes in obese dogs. Br J Nutr (2007) 0.94
Effect of atorvastatin on apolipoprotein B100 containing lipoprotein metabolism in type-2 diabetes. J Pharmacol Exp Ther (2003) 0.93
Rapid weight loss with a high-protein low-energy diet allows the recovery of ideal body composition and insulin sensitivity in obese dogs. J Nutr (2004) 0.93
WSAVA Nutritional Assessment Guidelines. J Small Anim Pract (2011) 0.92
Effect of low-fat, fermented milk enriched with plant sterols on serum lipid profile and oxidative stress in moderate hypercholesterolemia. Am J Clin Nutr (2007) 0.92
Development of a rapid and convenient method to purify mucins and determine their in vivo synthesis rate in rats. Anal Biochem (2002) 0.91
A fourth locus for autosomal dominant hypercholesterolemia maps at 16q22.1. Eur J Hum Genet (2010) 0.91
PCSK9: a promising therapeutic target for dyslipidemias? Trends Endocrinol Metab (2006) 0.90
Perinatal undernutrition-induced obesity is independent of the developmental programming of feeding. Physiol Behav (2008) 0.89
Resistant starch modulates in vivo colonic butyrate uptake and its oxidation in rats with dextran sulfate sodium-induced colitis. J Nutr (2004) 0.88
Lipid profile and insulin sensitivity in rats fed with high-fat or high-fructose diets. Br J Nutr (2011) 0.87
Selective uptake of high density lipoproteins cholesteryl ester in the dog, a species lacking in cholesteryl ester transfer protein activity; An in vivo approach using stable isotopes. Comp Biochem Physiol B Biochem Mol Biol (2004) 0.87
Evaluation of body composition in dogs by isotopic dilution using a low-cost technique, Fourier-transform infrared spectroscopy. J Nutr (2002) 0.87
Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets. Nutr Metab (Lond) (2013) 0.87
Association between plasma PCSK9 and gamma-glutamyl transferase levels in diabetic patients. Atherosclerosis (2010) 0.86
Effect of glutamine on glutathione kinetics in vivo in dogs. J Nutr Biochem (2006) 0.86
Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats. Br J Nutr (2010) 0.86
PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion. Biochem Biophys Res Commun (2009) 0.86
Lipoproteins abnormalities in obese insulin-resistant dogs. Metabolism (2003) 0.85
Comparing three pedagogical approaches to psychomotor skills acquisition. Am J Surg (2011) 0.84
Spontaneous hormonal variations in male cats following gonadectomy. J Feline Med Surg (2006) 0.84
Use of advanced cluster analysis to characterize fish consumption patterns and methylmercury dietary exposures from fish and other sea foods among pregnant women. J Expo Sci Environ Epidemiol (2009) 0.84
Lack of association between plasma PCSK9 and LDL-apoB100 catabolism in patients with uncontrolled type 2 diabetes. Atherosclerosis (2011) 0.83
The effects of obesity-associated insulin resistance on mRNA expression of peroxisome proliferator-activated receptor-gamma target genes, in dogs. Br J Nutr (2007) 0.83
Cholesterol lowering effect of a soy drink enriched with plant sterols in a French population with moderate hypercholesterolemia. Lipids Health Dis (2008) 0.83
Fenofibrate lowers lipid parameters in obese dogs. J Nutr (2006) 0.83
Quality of life with diabetes-associated foot complications: comparison between lower-limb amputation and chronic foot ulceration. Foot Ankle Int (2008) 0.83
Nicotinic acid decreases apolipoprotein B100-containing lipoprotein levels by reducing hepatic very low density lipoprotein secretion through a possible diacylglycerol acyltransferase 2 inhibition in obese dogs. J Pharmacol Exp Ther (2010) 0.81
Thiazolidinedione use is not associated with worse cardiovascular outcomes: a study in 28,332 high risk patients with diabetes in routine clinical practice: brief title: thiazolidinedione use and mortality. Int J Cardiol (2012) 0.81
[Radiotherapy and atherosclerosis: current data and issues]. Med Sci (Paris) (2010) 0.81
Serum insulin-like growth factor type 1 concentrations in healthy dogs and dogs with spontaneous primary hypothyroidism. Vet J (2011) 0.81
Indirect prediction of total body water content in healthy adult Beagles by single-frequency bioelectrical impedance analysis. Am J Vet Res (2015) 0.80
Influence of different levels and sources of resistant starch on faecal quality of dogs of various body sizes. Br J Nutr (2011) 0.80
WSAVA Nutritional Assessment Guidelines. Compend Contin Educ Vet (2011) 0.80
Does enteral glutamine modulate whole-body leucine kinetics in hypercatabolic dogs in a fed state? Metabolism (2002) 0.79
A milk-based wolfberry preparation prevents prenatal stress-induced cognitive impairment of offspring rats, and inhibits oxidative damage and mitochondrial dysfunction in vitro. Neurochem Res (2010) 0.78
Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats. Br J Nutr (2011) 0.78
Chicory increases acetate turnover, but not propionate and butyrate peripheral turnovers in rats. Br J Nutr (2007) 0.78
Gastric emptying rate is inversely related to body weight in dog breeds of different sizes. J Nutr (2004) 0.78
Do infants and toddlers prefer nasal swabs or washes for specimen collection? Pediatr Infect Dis J (2010) 0.78
The differential apoA-I enrichment of prebeta1 and alphaHDL is detectable by gel filtration separation. J Lipid Res (2002) 0.77
Serum resistance to singlet oxygen in patients with diabetes mellitus in comparison to healthy donors. Metabolism (2011) 0.77
Low rate of production of apolipoproteins B100 and AI in 2 patients with Anderson disease (chylomicron retention disease). Arterioscler Thromb Vasc Biol (2012) 0.77
Atorvastatin increases intestinal cholesterol absorption in dogs. J Nutr (2006) 0.77
In situ NMR spectroelectrochemistry for the structure elucidation of unstable intermediate metabolites. Anal Bioanal Chem (2013) 0.77
Diet-induced dyslipidemia impairs reverse cholesterol transport in hamsters. Eur J Clin Invest (2011) 0.77
Laparoscopic Gastric Banding in Obese Patients with Sleep Apnea: A 3-Year Controlled Study and Follow-up After 10 Years. Obes Surg (2015) 0.77
Quantitative measurement of lipoprotein particles containing both apolipoprotein AIV and apolipoprotein B in human plasma by a noncompetitive ELISA. Clin Chem (2002) 0.76
Voltammetry coupled to mass spectrometry in the presence of isotope 18O labeled water for the prediction of oxidative transformation pathways of activated aromatic ethers: acebutolol. Anal Chim Acta (2012) 0.76
Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet. PLoS One (2013) 0.76
Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry. Anal Bioanal Chem (2013) 0.75
No effect of conjugated linoleic acid or Garcinia cambogia on fat-free mass, and energy expenditure in normal cats. J Nutr (2006) 0.75
The knowledge levels and opinions of biomedical students regarding the human papillomavirus quadrivalent (types 6, 11, 16, and 18) recombinant vaccine. J Pharm Pract (2010) 0.75
Modulation of uncoupling protein 1 and peroxisome proliferator-activated receptor gamma expression in adipose tissue in obese insulin-resistant dogs. J Nutr (2004) 0.75
[Intestinal cholesterol absorption and NPC1-L1]. Med Sci (Paris) (2004) 0.75
[Does a slight overweight increase life expectancy?]. Rev Prat (2015) 0.75
Protein intake does not affect insulin sensitivity in normal weight cats. J Nutr (2006) 0.75
Robotic Colorectal Surgery: Our Initial Experience. Am Surg (2016) 0.75
Analytical electron tomography mapping of the SiC pore oxidation at the nanoscale. Nanoscale (2010) 0.75
A Long-Term Model of the Glucose-Insulin Dynamics of Type 1 Diabetes. IEEE Trans Biomed Eng (2015) 0.75
Selective oxidation of a single primary alcohol function in oligopyridine frameworks. Org Lett (2004) 0.75
Acetogenic fibers reduce fasting glucose turnover but not peripheral insulin resistance in metabolic syndrome patients. Clin Nutr (2010) 0.75
TiO2/β-SiC foam-structured photoreactor for continuous wastewater treatment. Environ Sci Pollut Res Int (2012) 0.75
[PCSK9: a new gene involved in familial hypercholesteremia]. Med Sci (Paris) (2004) 0.75
Solid-phase microextraction method for carbon isotopic analysis of volatile carboxylic acids in human plasma by gas chromatography/combustion/isotope ratio mass spectrometry. Rapid Commun Mass Spectrom (2006) 0.75
Model Free iPID Control for Glycemia Regulation of Type-1 Diabetes. IEEE Trans Biomed Eng (2017) 0.75
The hyperenergetic-fed obese dog, a model of disturbance of apolipoprotein B-100 metabolism associated with insulin resistance: kinetic study using stable isotopes. Metabolism (2008) 0.75