Published in EMBO J on May 15, 2003
Aneuploidy and isochromosome formation in drug-resistant Candida albicans. Science (2006) 4.09
The 'obligate diploid' Candida albicans forms mating-competent haploids. Nature (2013) 2.93
A phenotypic profile of the Candida albicans regulatory network. PLoS Genet (2009) 2.86
The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. PLoS Biol (2008) 2.78
Identification and characterization of a Candida albicans mating pheromone. Mol Cell Biol (2003) 2.42
Molecular phylogenetics of Candida albicans. Eukaryot Cell (2007) 2.41
Mechanistic plasticity of sexual reproduction and meiosis in the Candida pathogenic species complex. Curr Biol (2009) 2.25
The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev (2010) 2.24
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. PLoS Genet (2009) 2.07
Polyploidy can drive rapid adaptation in yeast. Nature (2015) 1.87
Genomic convergence toward diploidy in Saccharomyces cerevisiae. PLoS Genet (2006) 1.80
Reversion of a fungal genetic code alteration links proteome instability with genomic and phenotypic diversification. Proc Natl Acad Sci U S A (2013) 1.75
A tetraploid intermediate precedes aneuploid formation in yeasts exposed to fluconazole. PLoS Biol (2014) 1.69
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth. Genome Res (2012) 1.65
The closely related species Candida albicans and Candida dubliniensis can mate. Eukaryot Cell (2004) 1.57
Illicit survival of cancer cells during polyploidization and depolyploidization. Cell Death Differ (2010) 1.57
Evolution of eukaryotic microbial pathogens via covert sexual reproduction. Cell Host Microbe (2010) 1.50
Genomic plasticity of the human fungal pathogen Candida albicans. Eukaryot Cell (2010) 1.46
Sex in fungi. Annu Rev Genet (2011) 1.45
Demonstration of loss of heterozygosity by single-nucleotide polymorphism microarray analysis and alterations in strain morphology in Candida albicans strains during infection. Eukaryot Cell (2005) 1.42
Stress alters rates and types of loss of heterozygosity in Candida albicans. MBio (2011) 1.38
Stress-induced phenotypic switching in Candida albicans. Mol Biol Cell (2009) 1.37
Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating. PLoS Pathog (2009) 1.35
Multilocus sequence typing reveals intrafamilial transmission and microevolutions of Candida albicans isolates from the human digestive tract. J Clin Microbiol (2006) 1.34
The use of yellow fluorescent hybrids to indicate mating in Trypanosoma brucei. Parasit Vectors (2008) 1.32
Parallels in fungal pathogenesis on plant and animal hosts. Eukaryot Cell (2006) 1.20
Regulation of white-opaque switching in Candida albicans. Med Microbiol Immunol (2010) 1.17
Recent, independent and anthropogenic origins of Trypanosoma cruzi hybrids. PLoS Negl Trop Dis (2011) 1.17
Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection. PLoS Pathog (2010) 1.17
Fungal sex and pathogenesis. Clin Microbiol Rev (2010) 1.16
Comparative genome analysis and gene finding in Candida species using CGOB. Mol Biol Evol (2013) 1.16
Aneuploid chromosomes are highly unstable during DNA transformation of Candida albicans. Eukaryot Cell (2009) 1.15
Flow cytometric analysis and microsatellite genotyping reveal extensive DNA content variation in Trypanosoma cruzi populations and expose contrasts between natural and experimental hybrids. Int J Parasitol (2009) 1.12
Evolution of mating within the Candida parapsilosis species group. Eukaryot Cell (2011) 1.06
Barrier activity in Candida albicans mediates pheromone degradation and promotes mating. Eukaryot Cell (2007) 1.06
Loss and gain of chromosome 5 controls growth of Candida albicans on sorbose due to dispersed redundant negative regulators. Proc Natl Acad Sci U S A (2005) 1.06
Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol (2013) 1.04
Polyploidy in fungi: evolution after whole-genome duplication. Proc Biol Sci (2012) 1.04
Mating is rare within as well as between clades of the human pathogen Candida albicans. Fungal Genet Biol (2007) 1.02
Gene Ontology and the annotation of pathogen genomes: the case of Candida albicans. Trends Microbiol (2009) 1.02
Genetic and phenotypic intra-species variation in Candida albicans. Genome Res (2014) 1.02
Hwp1 and related adhesins contribute to both mating and biofilm formation in Candida albicans. Eukaryot Cell (2009) 0.99
Interspecies pheromone signaling promotes biofilm formation and same-sex mating in Candida albicans. Proc Natl Acad Sci U S A (2011) 0.99
The role of duplications in the evolution of genomes highlights the need for evolutionary-based approaches in comparative genomics. Biol Direct (2011) 0.98
Ploidy reduction in Saccharomyces cerevisiae. Biol Lett (2008) 0.97
Origins of eukaryotic sexual reproduction. Cold Spring Harb Perspect Biol (2014) 0.96
Identification and characterization of MFA1, the gene encoding Candida albicans a-factor pheromone. Eukaryot Cell (2007) 0.96
A genetic code alteration is a phenotype diversity generator in the human pathogen Candida albicans. PLoS One (2007) 0.95
The role of phenotypic switching in the basic biology and pathogenesis of Candida albicans. J Oral Microbiol (2014) 0.94
Effects of ploidy and mating type on virulence of Candida albicans. Infect Immun (2005) 0.93
Does stress induce (para)sex? Implications for Candida albicans evolution. Trends Genet (2012) 0.93
Candida albicans forms a specialized "sexual" as well as "pathogenic" biofilm. Eukaryot Cell (2013) 0.93
Efficient and rapid identification of Candida albicans allelic status using SNP-RFLP. FEMS Yeast Res (2009) 0.93
The cryptic sexual strategies of human fungal pathogens. Nat Rev Microbiol (2014) 0.91
Effect of the major repeat sequence on mitotic recombination in Candida albicans. Genetics (2006) 0.91
Candida albicans: A Model Organism for Studying Fungal Pathogens. ISRN Microbiol (2012) 0.91
Evolutionary rate covariation in meiotic proteins results from fluctuating evolutionary pressure in yeasts and mammals. Genetics (2012) 0.90
Rad52 function prevents chromosome loss and truncation in Candida albicans. Mol Microbiol (2011) 0.89
Virulence and karyotype analyses of rad52 mutants of Candida albicans: regeneration of a truncated chromosome of a reintegrant strain (rad52/RAD52) in the host. Infect Immun (2005) 0.89
Fungal meiosis and parasexual reproduction--lessons from pathogenic yeast. Curr Opin Microbiol (2009) 0.88
Sexual reproduction in the Candida clade: cryptic cycles, diverse mechanisms, and alternative functions. Cell Mol Life Sci (2010) 0.88
Yeast: a simple model system to study complex phenomena of aneuploidy. FEMS Microbiol Rev (2013) 0.88
Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity. Cold Spring Harb Perspect Med (2014) 0.87
Identification of a cell death pathway in Candida albicans during the response to pheromone. Eukaryot Cell (2010) 0.87
Clonal reproduction in fungi. Proc Natl Acad Sci U S A (2015) 0.87
Loss and fragmentation of chromosome 5 are major events linked to the adaptation of rad52-DeltaDelta strains of Candida albicans to sorbose. Fungal Genet Biol (2007) 0.87
A single SNP, G929T (Gly310Val), determines the presence of a functional and a non-functional allele of HIS4 in Candida albicans SC5314: detection of the non-functional allele in laboratory strains. Fungal Genet Biol (2007) 0.87
Defining pheromone-receptor signaling in Candida albicans and related asexual Candida species. Mol Biol Cell (2011) 0.87
Shift and adapt: the costs and benefits of karyotype variations. Curr Opin Microbiol (2015) 0.86
The Candida pathogenic species complex. Cold Spring Harb Perspect Med (2014) 0.86
Evidence and importance of genetic exchange among field populations of Trypanosoma cruzi. Acta Trop (2015) 0.86
Candida albicans genome sequence: a platform for genomics in the absence of genetics. Genome Biol (2004) 0.84
Ploidy variation in multinucleate cells changes under stress. Mol Biol Cell (2015) 0.84
Microbial genetics: Love the one you're with. Nature (2009) 0.83
Parasexuality and ploidy change in Candida tropicalis. Eukaryot Cell (2013) 0.83
Candida albicans the chameleon: transitions and interactions between multiple phenotypic states confer phenotypic plasticity. Curr Opin Microbiol (2015) 0.82
Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans. Genetics (2015) 0.82
Role of the homologous recombination genes RAD51 and RAD59 in the resistance of Candida albicans to UV light, radiomimetic and anti-tumor compounds and oxidizing agents. Fungal Genet Biol (2010) 0.82
The Candida Genome Database (CGD): incorporation of Assembly 22, systematic identifiers and visualization of high throughput sequencing data. Nucleic Acids Res (2016) 0.81
Ploidy of cell-sorted trophic and cystic forms of Pneumocystis carinii. PLoS One (2011) 0.80
Living and thriving on the skin: Malassezia genomes tell the story. MBio (2013) 0.80
Multiple Origins of the Pathogenic Yeast Candida orthopsilosis by Separate Hybridizations between Two Parental Species. PLoS Genet (2016) 0.79
Analogous telesensing pathways regulate mating and virulence in two opportunistic human pathogens. MBio (2010) 0.79
Conserved WCPL and CX4C domains mediate several mating adhesin interactions in Saccharomyces cerevisiae. Genetics (2009) 0.79
Genome management and mismanagement-cell-level opportunities and challenges of whole-genome duplication. Genes Dev (2015) 0.78
The parasexual lifestyle of Candida albicans. Curr Opin Microbiol (2015) 0.78
Large-Scale Chromosomal Changes and Associated Fitness Consequences in Pathogenic Fungi. Curr Fungal Infect Rep (2014) 0.77
Communication in fungi. Int J Microbiol (2011) 0.77
Homothallism: an umbrella term for describing diverse sexual behaviours. IMA Fungus (2015) 0.77
Models for the evolution of GC content in asexual fungi Candida albicans and C. dubliniensis. Genome Biol Evol (2013) 0.76
Genetic Dissection of Sexual Reproduction in a Primary Homothallic Basidiomycete. PLoS Genet (2016) 0.76
A stable hybrid containing haploid genomes of two obligate diploid Candida species. Eukaryot Cell (2013) 0.76
A FACS-optimized screen identifies regulators of genome stability in Candida albicans. Eukaryot Cell (2015) 0.76
Selective Advantages of a Parasexual Cycle for the Yeast Candida albicans. Genetics (2015) 0.76
Mosaicism for combined tetrasomy of chromosomes 8 and 18 in a dysmorphic child: a result of failed tetraploidy correction? BMC Med Genet (2009) 0.75
Gene regulatory network plasticity predates a switch in function of a conserved transcription regulator. Elife (2017) 0.75
Candida albicans Kinesin Kar3 Depends on a Cik1-Like Regulatory Partner Protein for Its Roles in Mating, Cell Morphogenesis, and Bipolar Spindle Formation. Eukaryot Cell (2015) 0.75
Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome. MBio (2016) 0.75
Fungal biology: Multiple mating strategies. Nature (2013) 0.75
Comparative genome analysis of Pseudogymnoascus spp. reveals primarily clonal evolution with small genome fragments exchanged between lineages. BMC Genomics (2015) 0.75
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
Isogenic strain construction and gene mapping in Candida albicans. Genetics (1993) 17.18
Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis (1999) 10.30
Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science (1994) 8.59
White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating. Cell (2002) 5.36
Evidence for mating of the "asexual" yeast Candida albicans in a mammalian host. Science (2000) 5.22
Induction of mating in Candida albicans by construction of MTLa and MTLalpha strains. Science (2000) 4.84
Identification of a mating type-like locus in the asexual pathogenic yeast Candida albicans. Science (1999) 4.14
Molecular markers reveal that population structure of the human pathogen Candida albicans exhibits both clonality and recombination. Proc Natl Acad Sci U S A (1996) 3.53
Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc Natl Acad Sci U S A (1996) 3.50
NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans. EMBO J (2001) 3.48
In Candida albicans, white-opaque switchers are homozygous for mating type. Genetics (2002) 2.96
Assignment of cloned genes to the seven electrophoretically separated Candida albicans chromosomes. Mol Cell Biol (1988) 2.78
NRG1, a repressor of filamentous growth in C.albicans, is down-regulated during filament induction. EMBO J (2001) 2.76
Genomic evidence for a complete sexual cycle in Candida albicans. Proc Natl Acad Sci U S A (2001) 2.52
Monosomy of a specific chromosome determines L-sorbose utilization: a novel regulatory mechanism in Candida albicans. Proc Natl Acad Sci U S A (1998) 2.36
Heat shock induces chromosome loss in the yeast Candida albicans. Mol Gen Genet (1985) 1.96
Gene regulation during high-frequency switching in Candida albicans. Microbiology (1997) 1.67
Appearance and properties of L-sorbose-utilizing mutants of Candida albicans obtained on a selective plate. Genetics (1999) 1.33
Toxicity of 2-deoxygalactose to Saccharomyces cerevisiae cells constitutively synthesizing galactose-metabolizing enzymes. Mol Cell Biol (1984) 1.32
Are Candida albicans natural populations subdivided? Trends Microbiol (1997) 1.29
Conservation of genetic linkage in nonisogenic isolates of Candida albicans. J Bacteriol (1983) 1.19
DLH1 is a functional Candida albicans homologue of the meiosis-specific gene DMC1. Genetics (1996) 1.12
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution. Science (2009) 5.37
White-opaque switching in Candida albicans is controlled by mating-type locus homeodomain proteins and allows efficient mating. Cell (2002) 5.36
Strains and strategies for large-scale gene deletion studies of the diploid human fungal pathogen Candida albicans. Eukaryot Cell (2005) 4.36
Evolution of a combinatorial transcriptional circuit: a case study in yeasts. Cell (2003) 4.13
Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity. Nat Genet (2010) 3.65
Evolution of alternative transcriptional circuits with identical logic. Nature (2006) 3.58
The evolution of combinatorial gene regulation in fungi. PLoS Biol (2008) 3.53
Interlocking transcriptional feedback loops control white-opaque switching in Candida albicans. PLoS Biol (2007) 3.27
Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes. EMBO J (2003) 3.26
Biofilm matrix regulation by Candida albicans Zap1. PLoS Biol (2009) 3.20
A human-curated annotation of the Candida albicans genome. PLoS Genet (2005) 3.04
In Candida albicans, white-opaque switchers are homozygous for mating type. Genetics (2002) 2.96
A phenotypic profile of the Candida albicans regulatory network. PLoS Genet (2009) 2.86
The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains. PLoS Biol (2008) 2.78
Epigenetic properties of white-opaque switching in Candida albicans are based on a self-sustaining transcriptional feedback loop. Proc Natl Acad Sci U S A (2006) 2.74
A recently evolved transcriptional network controls biofilm development in Candida albicans. Cell (2012) 2.56
Induction of the Candida albicans filamentous growth program by relief of transcriptional repression: a genome-wide analysis. Mol Biol Cell (2005) 2.56
Identification and characterization of a Candida albicans mating pheromone. Mol Cell Biol (2003) 2.42
Evolution of eukaryotic transcription circuits. Science (2008) 2.24
Haploinsufficiency-based large-scale forward genetic analysis of filamentous growth in the diploid human fungal pathogen C.albicans. EMBO J (2003) 2.11
Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol (2005) 2.09
MochiView: versatile software for genome browsing and DNA motif analysis. BMC Biol (2010) 1.89
Intercalation of a new tier of transcription regulation into an ancient circuit. Nature (2010) 1.78
Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence. Mol Biol Cell (2005) 1.63
The transcriptomes of two heritable cell types illuminate the circuit governing their differentiation. PLoS Genet (2010) 1.59
Differential phagocytosis of white versus opaque Candida albicans by Drosophila and mouse phagocytes. PLoS One (2008) 1.53
Genomic dissection of the cell-type-specification circuit in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (2004) 1.52
White-opaque switching in Candida albicans. Curr Opin Microbiol (2009) 1.43
Genetics of Candida albicans, a diploid human fungal pathogen. Annu Rev Genet (2007) 1.37
Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae. Mol Biol Cell (2004) 1.34
The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans. Mol Microbiol (2006) 1.32
Computational and experimental approaches double the number of known introns in the pathogenic yeast Candida albicans. Genome Res (2007) 1.24
White-opaque switching in natural MTLa/α isolates of Candida albicans: evolutionary implications for roles in host adaptation, pathogenesis, and sex. PLoS Biol (2013) 1.24
Extensive DNA-binding specificity divergence of a conserved transcription regulator. Proc Natl Acad Sci U S A (2011) 1.24
Protein modularity, cooperative binding, and hybrid regulatory states underlie transcriptional network diversification. Cell (2012) 1.21
Nuclear fusion occurs during mating in Candida albicans and is dependent on the KAR3 gene. Mol Microbiol (2005) 1.19
Candida albicans commensalism and pathogenicity are intertwined traits directed by a tightly knit transcriptional regulatory circuit. PLoS Biol (2013) 1.18
Structure of the transcriptional network controlling white-opaque switching in Candida albicans. Mol Microbiol (2013) 1.14
Genetics and molecular biology in Candida albicans. Methods Enzymol (2010) 1.13
Evolution of transcription networks--lessons from yeasts. Curr Biol (2010) 1.12
Following gene duplication, paralog interference constrains transcriptional circuit evolution. Science (2013) 1.10
Distinct class of DNA-binding domains is exemplified by a master regulator of phenotypic switching in Candida albicans. Proc Natl Acad Sci U S A (2010) 1.10
Genetic control of conventional and pheromone-stimulated biofilm formation in Candida albicans. PLoS Pathog (2013) 1.09
Evolution of yeast noncoding RNAs reveals an alternative mechanism for widespread intron loss. Science (2010) 1.08
A conserved transcriptional regulator governs fungal morphology in widely diverged species. Genetics (2011) 1.07
An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth. PLoS Genet (2009) 1.04
Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains. Proc Natl Acad Sci U S A (2013) 1.03
Ash1 protein, an asymmetrically localized transcriptional regulator, controls filamentous growth and virulence of Candida albicans. Mol Cell Biol (2002) 0.99
Candida albicans white and opaque cells undergo distinct programs of filamentous growth. PLoS Pathog (2013) 0.98
Temporal anatomy of an epigenetic switch in cell programming: the white-opaque transition of C. albicans. Mol Microbiol (2010) 0.95
Genome-wide analysis of the functions of a conserved surface on the corepressor Tup1. Mol Biol Cell (2005) 0.86
Evaluation of a thermoprotective gel for hydrodissection during percutaneous microwave ablation: in vivo results. Cardiovasc Intervent Radiol (2014) 0.85
Phagocytosis of Candida albicans by RNAi-treated Drosophila S2 cells. Methods Mol Biol (2009) 0.77