Published in Am J Physiol Heart Circ Physiol on May 15, 2003
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature (2012) 3.63
Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circ Res (2004) 2.11
A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y. J Clin Invest (2006) 1.79
Targeted deletion of kcne2 impairs ventricular repolarization via disruption of I(K,slow1) and I(to,f). FASEB J (2008) 1.54
Mouse models of long QT syndrome. J Physiol (2006) 1.36
Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. FASEB J (2007) 1.23
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol (2006) 1.22
Focal gap junction uncoupling and spontaneous ventricular ectopy. Am J Physiol Heart Circ Physiol (2005) 1.08
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Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. J Mol Cell Cardiol (2014) 0.96
Short-term pacing in the mouse alters cardiac expression of connexin43. BMC Physiol (2008) 0.82
Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents. Am J Physiol Heart Circ Physiol (2008) 0.79
Mitogen-activated protein kinase kinase 4 deficiency in cardiomyocytes causes connexin 43 reduction and couples hypertrophic signals to ventricular arrhythmogenesis. J Biol Chem (2011) 0.78
Transcription factor ETV1 is essential for rapid conduction in the heart. J Clin Invest (2016) 0.77
Arrhythmogenic properties of dismantling cadherin-mediated adhesion in murine hearts. J Biomed Res (2010) 0.75
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Efficacy of antibiotic prophylaxis before the implantation of pacemakers and cardioverter-defibrillators: results of a large, prospective, randomized, double-blinded, placebo-controlled trial. Circ Arrhythm Electrophysiol (2009) 3.16
Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation (2007) 2.93
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J (2002) 2.74
Multi-sensor esophageal temperature probe used during radiofrequency ablation for atrial fibrillation is associated with increased intraluminal temperature detection and increased risk of esophageal injury compared to single-sensor probe. J Cardiovasc Electrophysiol (2013) 2.65
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. Proc Natl Acad Sci U S A (2003) 2.48
Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis. Circ Res (2005) 2.44
Modulation of cardiac gap junction expression and arrhythmic susceptibility. Circ Res (2004) 2.11
Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes. Heart Rhythm (2011) 2.10
Isl1Cre reveals a common Bmp pathway in heart and limb development. Development (2006) 2.04
4-[18F]-tetraphenylphosphonium as a PET tracer for myocardial mitochondrial membrane potential. JACC Cardiovasc Imaging (2012) 1.94
Neuregulin-1 promotes formation of the murine cardiac conduction system. Proc Natl Acad Sci U S A (2002) 1.81
Analysis of the left atrial appendage by magnetic resonance angiography in patients with atrial fibrillation. Heart Rhythm (2006) 1.75
Myocardial Notch signaling reprograms cardiomyocytes to a conduction-like phenotype. Circulation (2012) 1.66
Spinal cord stimulation protects against atrial fibrillation induced by tachypacing. Heart Rhythm (2012) 1.49
Catheter ablation of scar-related atypical atrial flutter. Europace (2013) 1.48
Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res (2005) 1.48
Ephaptic conduction in a cardiac strand model with 3D electrodiffusion. Proc Natl Acad Sci U S A (2008) 1.46
Altered right atrial excitation and propagation in connexin40 knockout mice. Circulation (2005) 1.46
Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. J Mol Cell Cardiol (2007) 1.42
Enhanced fibroblast-myocyte interactions in response to cardiac injury. Circ Res (2010) 1.42
Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart. Circ Res (2008) 1.41
Purkinje cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted therapy. Circ Res (2010) 1.41
Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia. Proc Natl Acad Sci U S A (2005) 1.38
Unpredictable battery depletion of St Jude Atlas II and Atlas+ II HF implantable cardioverter-defibrillators. Heart Rhythm (2011) 1.38
Contactin-2 expression in the cardiac Purkinje fiber network. Circ Arrhythm Electrophysiol (2010) 1.33
Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Proc Natl Acad Sci U S A (2007) 1.33
Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias. Circ Res (2011) 1.32
Prevention of ventricular arrhythmias with sarcoplasmic reticulum Ca2+ ATPase pump overexpression in a porcine model of ischemia reperfusion. Circulation (2008) 1.30
Cell coupling between ventricular myocyte pairs from connexin43-deficient murine hearts. Circ Res (2003) 1.29
Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways. J Clin Invest (2011) 1.28
Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts. FASEB J (2007) 1.23
Proliferation of adult sertoli cells following conditional knockout of the Gap junctional protein GJA1 (connexin 43) in mice. Biol Reprod (2007) 1.23
Consequences of cardiac myocyte-specific ablation of KATP channels in transgenic mice expressing dominant negative Kir6 subunits. Am J Physiol Heart Circ Physiol (2006) 1.22
Second harmonic generation imaging and Fourier transform spectral analysis reveal damage in fatigue-loaded tendons. Ann Biomed Eng (2010) 1.21
Reduced intercellular coupling leads to paradoxical propagation across the Purkinje-ventricular junction and aberrant myocardial activation. Proc Natl Acad Sci U S A (2005) 1.21
Assessment of catheter tip contact force resulting in cardiac perforation in swine atria using force sensing technology. Circ Arrhythm Electrophysiol (2011) 1.20
Timing of the most recent device procedure influences the clinical outcome of lead-associated endocarditis results of the MEDIC (Multicenter Electrophysiologic Device Infection Cohort). J Am Coll Cardiol (2012) 1.20
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J (2012) 1.17
CMR quantification of myocardial scar provides additive prognostic information in nonischemic cardiomyopathy. JACC Cardiovasc Imaging (2013) 1.17
The organization of adherens junctions and desmosomes at the cardiac intercalated disc is independent of gap junctions. J Cell Sci (2003) 1.16
Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias. Circulation (2005) 1.15
The cardiac conduction system. Circulation (2011) 1.11
The cardiac fibroblast: functional and electrophysiological considerations in healthy and diseased hearts. J Cardiovasc Pharmacol (2011) 1.09
Focal gap junction uncoupling and spontaneous ventricular ectopy. Am J Physiol Heart Circ Physiol (2005) 1.08
Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. J Clin Invest (2014) 1.08
Connexin40 imparts conduction heterogeneity to atrial tissue. Circ Res (2008) 1.06
Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood (2012) 1.05
Visually-guided balloon catheter ablation of atrial fibrillation: experimental feasibility and first-in-human multicenter clinical outcome. Circulation (2009) 1.04
Transfection of mammalian cells with connexins and measurement of voltage sensitivity of their gap junctions. Nat Protoc (2006) 1.04
Induction and patterning of the cardiac conduction system. Int J Dev Biol (2002) 1.03
Respiratory compensation improves the accuracy of electroanatomic mapping of the left atrium and pulmonary veins during atrial fibrillation ablation. J Interv Card Electrophysiol (2011) 1.03
Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. Circ Arrhythm Electrophysiol (2011) 1.00
Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells. Proc Natl Acad Sci U S A (2012) 0.99
Embryonic conduction tissue: a spatial correlation with adult arrhythmogenic areas. J Cardiovasc Electrophysiol (2004) 0.97
The relationships between cyclic fatigue loading, changes in initial mechanical properties, and the in vivo temporal mechanical response of the rat patellar tendon. J Biomech (2011) 0.97
The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Anat Embryol (Berl) (2004) 0.96
Rapid acquisition of high-resolution electroanatomical maps using a novel multielectrode mapping system. J Interv Card Electrophysiol (2012) 0.95
Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias. Circulation (2011) 0.95
Analysis of the left atrial appendage morphology by intracardiac echocardiography in patients with atrial fibrillation. J Interv Card Electrophysiol (2011) 0.95
Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy. Cell Commun Adhes (2006) 0.95
Molecular response of the patellar tendon to fatigue loading explained in the context of the initial induced damage and number of fatigue loading cycles. J Orthop Res (2012) 0.93
Left atrial tachycardia originating from the mitral annulus-aorta junction. Circulation (2004) 0.92
Transitions in ventricular activation revealed by two-dimensional optical mapping. Anat Rec A Discov Mol Cell Evol Biol (2004) 0.91
The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load. FASEB J (2011) 0.91
Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts. J Physiol (2014) 0.90
PCP4 regulates Purkinje cell excitability and cardiac rhythmicity. J Clin Invest (2014) 0.90
Sorcin regulates excitation-contraction coupling in the heart. J Biol Chem (2003) 0.89
Toward an understanding of the genetics of murine cardiac pacemaking and conduction system development. Anat Rec A Discov Mol Cell Evol Biol (2004) 0.88
The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice. Biochem J (2013) 0.87
Cycle-dependent matrix remodeling gene expression response in fatigue-loaded rat patellar tendons. J Orthop Res (2010) 0.87
Alterations of intercellular communication in neonatal cardiac myocytes from connexin43 null mice. Cardiovasc Res (2004) 0.86
Expression of a sorcin missense mutation in the heart modulates excitation-contraction coupling. FASEB J (2006) 0.86
Molecular and functional maturation of the murine cardiac conduction system. Trends Cardiovasc Med (2003) 0.86
GATA factors efficiently direct cardiac fate from embryonic stem cells. Development (2013) 0.86
Gap junctions and propagation of the cardiac action potential. Adv Cardiol (2006) 0.84
Severity of esophageal injury predicts time to healing after radiofrequency catheter ablation for atrial fibrillation. Heart Rhythm (2011) 0.83
Channeling diversity: gap junction expression in the heart. Heart Rhythm (2011) 0.83
Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure. Am J Physiol Heart Circ Physiol (2011) 0.83
Designer gap junctions that prevent cardiac arrhythmias. Trends Cardiovasc Med (2012) 0.82
Complex genomic rearrangement in CCS-LacZ transgenic mice. Genesis (2007) 0.82
Understanding conduction system development: a hop, skip and jump away? Circ Res (2005) 0.81
The origin and arrhythmogenic potential of fibroblasts in cardiac disease. J Cardiovasc Transl Res (2012) 0.80
Fibroblast KATP currents modulate myocyte electrophysiology in infarcted hearts. Am J Physiol Heart Circ Physiol (2013) 0.79
Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cells. Stem Cells (2015) 0.79
Decreased connexin43 expression in the mouse heart potentiates pacing-induced remodeling of repolarizing currents. Am J Physiol Heart Circ Physiol (2008) 0.79
Nav-igating through a complex landscape: SCN10A and cardiac conduction. J Clin Invest (2014) 0.79
Non-Vitamin K Antagonist Oral Anticoagulants and Antiplatelet Therapy for Stroke Prevention in Patients With Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials. Cardiol Rev (2016) 0.78
Connexin43 cardiac gap junction remodeling: lessons from genetically engineered murine models. J Membr Biol (2012) 0.78