Published in Eur J Biochem on May 01, 2003
The metabolic enzyme CTP synthase forms cytoskeletal filaments. Nat Cell Biol (2010) 2.01
Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotransferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targets. Biochemistry (2004) 1.11
Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex. Biochemistry (2005) 0.98
An unsymmetrical approach to the synthesis of bismethylene triphosphate analogues. Org Lett (2006) 0.97
Kinetics and thermodynamics of mandelate racemase catalysis. Biochemistry (2002) 0.94
Oxidative stress response in the opportunistic oral pathogen Fusobacterium nucleatum. Proteomics (2011) 0.93
Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium. Proteomics (2008) 0.86
Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli. Biochem J (2008) 0.85
Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase. Biochem J (2003) 0.84
Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel. Eur J Biochem (2004) 0.82
Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP. Biochim Biophys Acta (2004) 0.81
Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax. J Biol Chem (2007) 0.81
Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells. Biochem J (2005) 0.81
Bismethylene triphosphate nucleotides of uridine 4-phosphate analogues: a new class of anionic pyrimidine nucleotide analogues. J Org Chem (2008) 0.81
Mutational analysis of the active site flap (20s loop) of mandelate racemase. Biochemistry (2007) 0.80
Proteomic investigation of glucose metabolism in the butyrate-producing gut anaerobe Fusobacterium varium. Proteomics (2007) 0.79
A continuous assay for alpha-methylacyl-coenzyme A racemase using circular dichroism. Anal Biochem (2009) 0.79
Synthesis of methylene- and difluoromethylenephosphonate analogues of uridine-4-phosphate and 3-deazauridine-4-phosphate. J Org Chem (2006) 0.79
Redefining the minimal substrate tolerance of mandelate racemase. Racemization of trifluorolactate. Biochemistry (2011) 0.78
Purification of recombinant mandelate racemase: improved catalytic activity. Protein Expr Purif (2009) 0.78
Kinetic characterization and quaternary structure of glutamate racemase from the periodontal anaerobe Fusobacterium nucleatum. Arch Biochem Biophys (2009) 0.78
Perturbing the hydrophobic pocket of mandelate racemase to probe phenyl motion during catalysis. Biochemistry (2005) 0.77
Interrogation of the active site of OMP decarboxylase from Escherichia coli with a substrate analogue bearing an anionic group at C6. Chem Commun (Camb) (2010) 0.77
Inhibition of mandelate racemase by the substrate-intermediate-product analogue 1,1-diphenyl-1-hydroxymethylphosphonate. Bioorg Med Chem Lett (2005) 0.77
Hydrophobic nature of the active site of mandelate racemase. Biochemistry (2004) 0.77
An assay for cytidine 5(')-triphosphate synthetase glutaminase activity using high performance liquid chromatography. Anal Biochem (2002) 0.77
Inhibition of mandelate racemase by alpha-fluorobenzylphosphonates. Bioorg Med Chem Lett (2003) 0.77
Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron. Biochemistry (2012) 0.77
The role of lysine residues 297 and 306 in nucleoside triphosphate regulation of E. coli CTP synthase: inactivation by 2',3'-dialdehyde ATP and mutational analyses. Biochim Biophys Acta (2005) 0.77
Intermediate analogue inhibitors of mandelate racemase: N-Hydroxyformanilide and cupferron. Bioorg Med Chem Lett (2006) 0.77
Synthesis of coenzyme A thioesters using methyl acyl phosphates in an aqueous medium. Org Biomol Chem (2014) 0.75
Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness. Bioorg Med Chem Lett (2011) 0.75
Ground state, intermediate, and multivalent nucleotide analogue inhibitors of cytidine 5'-triphosphate synthase. ChemMedChem (2008) 0.75
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. Bioorg Med Chem Lett (2009) 0.75
Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode. Biochemistry (2014) 0.75