Published in Eur J Biochem on May 01, 2003
Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxid Redox Signal (2010) 1.64
Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress. Biochem Soc Trans (2008) 1.22
Mitochondrial Lon protease is a human stress protein. Free Radic Biol Med (2009) 1.18
Increasing organismal healthspan by enhancing mitochondrial protein quality control. Nat Cell Biol (2009) 1.17
Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging. Redox Biol (2013) 1.00
Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production? Semin Cell Dev Biol (2012) 0.96
Impairment of lon-induced protection against the accumulation of oxidized proteins in senescent wi-38 fibroblasts. J Gerontol A Biol Sci Med Sci (2011) 0.94
Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging. J Gerontol A Biol Sci Med Sci (2014) 0.92
Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers. Oncogenesis (2013) 0.89
Mitochondrial protein quality control: the mechanisms guarding mitochondrial health. Antioxid Redox Signal (2015) 0.88
Matrix proteases in mitochondrial DNA function. Biochim Biophys Acta (2011) 0.87
Age- and calorie restriction-related changes in rat brain mitochondrial DNA and TFAM binding. Age (Dordr) (2012) 0.85
Age modulates Fe3O4 nanoparticles liver toxicity: dose-dependent decrease in mitochondrial respiratory chain complexes activities and coupling in middle-aged as compared to young rats. Biomed Res Int (2014) 0.85
Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species. Biogerontology (2013) 0.84
Control of mitochondrial integrity in ageing and disease. Philos Trans R Soc Lond B Biol Sci (2014) 0.83
Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain. Nat Commun (2013) 0.82
Proteomic changes in bovine heart mitochondria with age: using a novel technique for organelle separation and enrichment. J Biomol Tech (2005) 0.80
Mitochondrial cereblon functions as a Lon-type protease. Sci Rep (2016) 0.79
Medical bioremediation of age-related diseases. Microb Cell Fact (2009) 0.76
Mitochondrial Lon protease in human disease and aging: Including an etiologic classification of Lon-related diseases and disorders. Free Radic Biol Med (2016) 0.75
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proc Natl Acad Sci U S A (2009) 2.14
Age-dependent declines in proteasome activity in the heart. Arch Biochem Biophys (2002) 1.52
Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation. J Biol Chem (2003) 1.51
Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver. Gastroenterology (2005) 1.42
Impairment of proteasome structure and function in aging. Int J Biochem Cell Biol (2002) 1.40
Minimum data set for nutritional intervention studies in elderly people. J Gerontol A Biol Sci Med Sci (2004) 1.40
Subcellular localization of methionine sulphoxide reductase A (MsrA): evidence for mitochondrial and cytosolic isoforms in rat liver cells. Biochem J (2003) 1.32
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem (2003) 1.32
Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway. J Cell Sci (2005) 1.26
Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Exp Gerontol (2006) 1.20
Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Arch Biochem Biophys (2006) 1.20
Proteasome function in aging and oxidative stress: implications in protein maintenance failure. Antioxid Redox Signal (2006) 1.20
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress. Antioxid Redox Signal (2010) 1.19
Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress. Ann N Y Acad Sci (2006) 1.15
Low-dose aspirin prevents age-related endothelial dysfunction in a mouse model of physiological aging. Am J Physiol Heart Circ Physiol (2008) 1.14
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage. J Biol Chem (2008) 1.10
Proteolysis, free radicals, and aging. Free Radic Biol Med (2002) 1.09
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts. Aging Cell (2010) 1.06
Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors. Biochimie (2007) 1.06
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. Mol Cell Biol (2003) 1.04
Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases. Biochim Biophys Acta (2005) 1.03
Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins. FEBS J (2008) 1.01
Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts. Ann N Y Acad Sci (2007) 1.01
Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy. J Biol Chem (2011) 0.96
Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome. Free Radic Biol Med (2012) 0.96
Characterization and role of protozoan parasite proteasomes. Trends Parasitol (2003) 0.96
Maintenance of proteins and aging: the role of oxidized protein repair. Free Radic Res (2006) 0.96
Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1. J Biol Chem (2010) 0.95
Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases. J Biol Chem (2004) 0.95
Impact of ageing on proteasome structure and function in human lymphocytes. Int J Biochem Cell Biol (2003) 0.95
Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress. Free Radic Biol Med (2005) 0.95
Age-dependent protein modifications and declining proteasome activity in the human lens. Arch Biochem Biophys (2004) 0.95
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A). Biogerontology (2009) 0.94
Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder. Eur J Pharmacol (2013) 0.94
Enzymatic reactions involved in the repair of oxidized proteins. Exp Gerontol (2004) 0.93
Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging. J Proteomics (2013) 0.93
Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases. Oxid Med Cell Longev (2012) 0.93
Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes. Free Radic Biol Med (2002) 0.91
Oxidative stress-induced proteome alterations target different cellular pathways in human myoblasts. Free Radic Biol Med (2011) 0.91
Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice. Antioxid Redox Signal (2010) 0.91
A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol Chem (2006) 0.91
Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart. Eur J Biochem (2004) 0.90
The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts. FEBS Lett (2004) 0.89
The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression. J Biol Chem (2009) 0.87
Impairment of methionine sulfoxide reductase during UV irradiation and photoaging. Exp Gerontol (2007) 0.87
The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care? Ageing Res Rev (2005) 0.87
Nutritional assessment of residents in long-term care facilities (LTCFs): recommendations of the task force on nutrition and ageing of the IAGG European region and the IANA. J Nutr Health Aging (2009) 0.86
Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion. Exp Gerontol (2006) 0.86
Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress. Antioxid Redox Signal (2009) 0.85
Correction of age-related polyuria by dDAVP: molecular analysis of aquaporins and urea transporters. Am J Physiol Renal Physiol (2002) 0.85
Expression and modification proteomics during skeletal muscle ageing. Biogerontology (2013) 0.85
Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging. Exp Gerontol (2012) 0.85
Age-related increase of protein glycation in peripheral blood lymphocytes is restricted to preferential target proteins. Exp Gerontol (2002) 0.85
Changes of the proteasomal system during the aging process. Prog Mol Biol Transl Sci (2012) 0.85
Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation. Antioxid Redox Signal (2006) 0.84
Cellular senescence in human keratinocytes: unchanged proteolytic capacity and increased protein load. Exp Gerontol (2003) 0.82
Gene expression in aging kidney and pituitary. Biogerontology (2004) 0.82
Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging. FEBS J (2007) 0.81
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurochem (2012) 0.81
Impact of hydrogen peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A. J Mol Biol (2009) 0.81
Catalase, a target of glycation damage in rat liver mitochondria with aging. Biochim Biophys Acta (2012) 0.80
Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation. Free Radic Biol Med (2009) 0.80
Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice. FEBS Lett (2005) 0.79
Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver. Biochim Biophys Acta (2013) 0.79
Proteasome and photoaging: the effects of UV irradiation. Ann N Y Acad Sci (2007) 0.79
Increased level of glycoxidation product N(epsilon)-(carboxymethyl)lysine in rat serum and urine proteins with aging: link with glycoxidative damage accumulation in kidney. Arch Biochem Biophys (2003) 0.78
Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378. Mol Cell Proteomics (2013) 0.78
Advanced glycation endproducts induce photocrosslinking and oxidation of bovine lens proteins through type-I mechanism. Photochem Photobiol (2008) 0.78
The second international conference "genetics of aging and longevity". Aging (Albany NY) (2012) 0.77
High-resolution mass spectrometry associated with data mining tools for the detection of pollutants and chemical characterization of honey samples. J Agric Food Chem (2014) 0.76
Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes. Exp Gerontol (2007) 0.76
Dietary fatty acids and oxidative stress in the heart mitochondria. Mitochondrion (2010) 0.76
Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C. Photochem Photobiol Sci (2010) 0.76
Prevention of dicarbonyl-mediated advanced glycation by glyoxalases: implication in skin aging. Biochem Soc Trans (2014) 0.76
Evidence of preferential protein targets for age-related modifications in peripheral blood lymphocytes. Ann N Y Acad Sci (2004) 0.76
[Objective improvement of sleep disorders in the elderly by a health education program]. Presse Med (2007) 0.76
Algae extract protection effect on oxidized protein level in human stratum corneum. Ann N Y Acad Sci (2004) 0.76
Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells. Free Radic Biol Med (2013) 0.76
Proteasome: a new target of UV radiations. Eur J Dermatol (2002) 0.75
Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration. Photochem Photobiol Sci (2008) 0.75
Endogenous C-terminal fragments of beta-amyloid precursor protein from Xenopus laevis skin exudate. Comp Biochem Physiol B Biochem Mol Biol (2006) 0.75
Clearance of genetic variants of amyloid β peptide by neuronal and non-neuronal cells. Protein Pept Lett (2013) 0.75
Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome. Biochim Biophys Acta (2011) 0.75
[Sleep, an issue for nurses and patients]. Soins Gerontol (2011) 0.75
Are expanded polyglutamine proteins a proteasome substrate? Rejuvenation Res (2004) 0.75
[Renal aging: risk factors and nephroprotection]. Presse Med (2009) 0.75