Published in J Cell Sci on January 25, 2005
Senescence-messaging secretome: SMS-ing cellular stress. Nat Rev Cancer (2009) 5.02
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc (2009) 4.47
Feedback between p21 and reactive oxygen production is necessary for cell senescence. Mol Syst Biol (2010) 3.27
A senescent cell bystander effect: senescence-induced senescence. Aging Cell (2012) 1.54
Senescence and apoptosis: dueling or complementary cell fates? EMBO Rep (2014) 1.21
Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. Mol Cancer (2008) 1.01
Differential effects of hypoxia on etoposide-induced apoptosis according to the cancer cell lines. Mol Cancer (2007) 0.94
Cellular senescence: unravelling complexity. Age (Dordr) (2009) 0.93
Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. PLoS One (2012) 0.89
Quantitative model of cell cycle arrest and cellular senescence in primary human fibroblasts. PLoS One (2012) 0.88
The Splicing Factor SRSF1 as a Marker for Endothelial Senescence. Front Physiol (2012) 0.88
Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence? Longev Healthspan (2014) 0.87
Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit. Free Radic Biol Med (2009) 0.86
Age-related cellular copper dynamics in the fungal ageing model Podospora anserina and in ageing human fibroblasts. PLoS One (2009) 0.83
Copper ability to induce premature senescence in human fibroblasts. Age (Dordr) (2011) 0.82
MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence. Oncotarget (2016) 0.81
Oxidative stress-associated senescence in dermal papilla cells of men with androgenetic alopecia. J Invest Dermatol (2015) 0.81
Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro. Am J Pathol (2007) 0.80
TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages. PLoS One (2013) 0.79
Antiphotoaging effect of conditioned medium of dedifferentiated adipocytes on skin in vivo and in vitro: a mechanistic study. Stem Cells Dev (2015) 0.78
MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. Aging (Albany NY) (2016) 0.77
Long-term quiescent fibroblast cells transit into senescence. PLoS One (2014) 0.77
UV, stress and aging. Dermatoendocrinol (2012) 0.76
Conserved genes and pathways in primary human fibroblast strains undergoing replicative and radiation induced senescence. Biol Res (2016) 0.75
Protective effects of adipose-derived stem cells secretome on human dermal fibroblasts from ageing damages. Int J Clin Exp Pathol (2015) 0.75
Ultraviolet B Inhibits IL-17A/TNF-α-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts. Front Immunol (2017) 0.75
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc (2009) 4.47
A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax. Blood (2011) 2.17
Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proc Natl Acad Sci U S A (2009) 2.14
HAGR: the Human Ageing Genomic Resources. Nucleic Acids Res (2005) 1.96
Chemotherapy-induced resistance by ATP-binding cassette transporter genes. Biochim Biophys Acta (2007) 1.79
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific. Aging Cell (2013) 1.56
Age-dependent declines in proteasome activity in the heart. Arch Biochem Biophys (2002) 1.52
Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation. J Biol Chem (2003) 1.51
Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver. Gastroenterology (2005) 1.42
Impairment of proteasome structure and function in aging. Int J Biochem Cell Biol (2002) 1.40
1912-2012: a century of research on Plasmodium vivax in vitro culture. Trends Parasitol (2013) 1.37
Subcellular localization of methionine sulphoxide reductase A (MsrA): evidence for mitochondrial and cytosolic isoforms in rat liver cells. Biochem J (2003) 1.32
Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes. Cancer Res (2004) 1.32
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease. J Neurochem (2003) 1.32
Replicative aging down-regulates the myogenic regulatory factors in human myoblasts. Biol Cell (2008) 1.30
Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging). Ann N Y Acad Sci (2007) 1.21
Mitochondrial protein oxidation and degradation in response to oxidative stress and aging. Exp Gerontol (2006) 1.20
Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes. Arch Biochem Biophys (2006) 1.20
Proteasome function in aging and oxidative stress: implications in protein maintenance failure. Antioxid Redox Signal (2006) 1.20
A microarray-based detection system for genetically modified (GM) food ingredients. Plant Mol Biol (2006) 1.19
Oxidized mitochondrial protein degradation and repair in aging and oxidative stress. Antioxid Redox Signal (2010) 1.19
Deoxynivalenol affects in vitro intestinal epithelial cell barrier integrity through inhibition of protein synthesis. Toxicol Appl Pharmacol (2010) 1.17
GenAge: a genomic and proteomic network map of human ageing. FEBS Lett (2004) 1.17
Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress. Ann N Y Acad Sci (2006) 1.15
Signal transduction in H2O2-induced senescence-like phenotype in human diploid fibroblasts. Free Radic Biol Med (2002) 1.13
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia. Clin Cancer Res (2006) 1.11
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage. J Biol Chem (2008) 1.10
Proteolysis, free radicals, and aging. Free Radic Biol Med (2002) 1.09
Screening of senescence-associated genes with specific DNA array reveals the role of IGFBP-3 in premature senescence of human diploid fibroblasts. Free Radic Biol Med (2008) 1.08
CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes. J Cell Sci (2006) 1.08
Serum N-glycan profile shift during human ageing. Exp Gerontol (2010) 1.08
Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model. Toxicol Lett (2011) 1.08
Proteome analysis and identification of symbiosis-related proteins from Medicago truncatula Gaertn. by two-dimensional electrophoresis and mass spectrometry. Electrophoresis (2002) 1.08
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts. Aging Cell (2010) 1.06
Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors. Biochimie (2007) 1.06
Potentiation of tumor necrosis factor-induced NF-kappa B activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of I kappa B alpha. Mol Cell Biol (2003) 1.04
Impact of the 10-valent pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine (PHiD-CV) on bacterial nasopharyngeal carriage. Vaccine (2011) 1.04
p38(MAPK) in the senescence of human and murine fibroblasts. Adv Exp Med Biol (2010) 1.04
Comparison of a novel whole blood transglutaminase-based ELISA with a whole blood rapid antibody test and established conventional serological celiac disease assays. J Pediatr Gastroenterol Nutr (2008) 1.04
Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases. Biochim Biophys Acta (2005) 1.03
Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia. Mol Cancer Ther (2006) 1.03
Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts. Ann N Y Acad Sci (2007) 1.01
Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins. FEBS J (2008) 1.01
UVB-induced premature senescence of human diploid skin fibroblasts. Int J Biochem Cell Biol (2002) 1.01
Stress-induced premature senescence and tissue ageing. Biochem Pharmacol (2002) 1.01
Cryopreserved reticulocytes derived from hematopoietic stem cells can be invaded by cryopreserved Plasmodium vivax isolates. PLoS One (2012) 1.01
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix. Eur J Biochem (2003) 1.00
Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium. Chem Biol Interact (2010) 0.99
How bioinformatics can help reverse engineer human aging. Ageing Res Rev (2004) 0.99
Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy. J Biol Chem (2011) 0.96
Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome. Free Radic Biol Med (2012) 0.96
Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray. Biochem Pharmacol (2002) 0.96
Role of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis. Free Radic Biol Med (2008) 0.96
Stress-induced premature senescence in BJ and hTERT-BJ1 human foreskin fibroblasts. FEBS Lett (2002) 0.96
Characterization and role of protozoan parasite proteasomes. Trends Parasitol (2003) 0.96
Maintenance of proteins and aging: the role of oxidized protein repair. Free Radic Res (2006) 0.96
Use of a low-density microarray for studying gene expression patterns induced by hepatotoxicants on primary cultures of rat hepatocytes. Toxicol Sci (2003) 0.96
Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide. Cell Stress Chaperones (2002) 0.96
Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1. J Biol Chem (2010) 0.95
Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases. J Biol Chem (2004) 0.95
Stress-induced premature senescence or stress-induced senescence-like phenotype: one in vivo reality, two possible definitions? ScientificWorldJournal (2002) 0.95
Age-dependent protein modifications and declining proteasome activity in the human lens. Arch Biochem Biophys (2004) 0.95
Impact of ageing on proteasome structure and function in human lymphocytes. Int J Biochem Cell Biol (2003) 0.95
Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress. Free Radic Biol Med (2005) 0.95
Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A). Biogerontology (2009) 0.94
Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging. J Proteomics (2013) 0.93
Enzymatic reactions involved in the repair of oxidized proteins. Exp Gerontol (2004) 0.93
Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases. Oxid Med Cell Longev (2012) 0.93
Normal or stress-induced fibroblast senescence involves COX-2 activity. Exp Cell Res (2007) 0.92
New chips for molecular biology and diagnostics. Biotechnol Annu Rev (2002) 0.92
Identification of p38MAPK-dependent genes with changed transcript abundance in H2O2-induced premature senescence of IMR-90 hTERT human fibroblasts. FEBS Lett (2006) 0.92
Impairment of proteasome function upon UVA- and UVB-irradiation of human keratinocytes. Free Radic Biol Med (2002) 0.91
Oxidative stress-induced proteome alterations target different cellular pathways in human myoblasts. Free Radic Biol Med (2011) 0.91
Hypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide. Neoplasia (2009) 0.91
A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms. Biol Chem (2006) 0.91
Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, calorie restriction, and dietary selenium in mice. Antioxid Redox Signal (2010) 0.91
Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart. Eur J Biochem (2004) 0.90
Establishment of H2O2-induced premature senescence in human fibroblasts concomitant with increased cellular production of H2O2. Ann N Y Acad Sci (2006) 0.90
Intermittent hypoxia is an angiogenic inducer for endothelial cells: role of HIF-1. Angiogenesis (2009) 0.89
The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts. FEBS Lett (2004) 0.89