Published in Biochim Biophys Acta on May 20, 2003
The Concise Guide to PHARMACOLOGY 2013/14: enzymes. Br J Pharmacol (2013) 5.57
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacol Rev (2006) 5.28
Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol (2006) 3.24
Cellular function and molecular structure of ecto-nucleotidases. Purinergic Signal (2012) 2.13
Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest (2012) 2.10
Loss-of-function ENPP1 mutations cause both generalized arterial calcification of infancy and autosomal-recessive hypophosphatemic rickets. Am J Hum Genet (2010) 1.93
Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal (2010) 1.91
Autosomal-recessive hypophosphatemic rickets is associated with an inactivation mutation in the ENPP1 gene. Am J Hum Genet (2010) 1.65
The role of membrane glycoprotein plasma cell antigen 1/ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities. Endocr Rev (2008) 1.52
Differential response of human basophil activation markers: a multi-parameter flow cytometry approach. Clin Mol Allergy (2008) 1.42
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine. J Biol Chem (2008) 1.31
Generalized arterial calcification of infancy and pseudoxanthoma elasticum: two sides of the same coin. Front Genet (2012) 1.21
Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism. J Bone Miner Res (2011) 1.19
Nucleotide signaling in nervous system development. Pflugers Arch (2006) 1.18
Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression. Diabetologia (2005) 1.15
Cloning, purification, and identification of the liver canalicular ecto-ATPase as NTPDase8. Am J Physiol Gastrointest Liver Physiol (2006) 1.14
Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification. Purinergic Signal (2006) 1.12
Activity-dependent release of adenosine: a critical re-evaluation of mechanism. Curr Neuropharmacol (2008) 1.11
Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2. Biochem J (2004) 1.08
A CD38/CD203a/CD73 ectoenzymatic pathway independent of CD39 drives a novel adenosinergic loop in human T lymphocytes. Oncoimmunology (2013) 1.07
Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic Signal (2006) 1.07
Ecto-5'-nucleotidase: Structure function relationships. Purinergic Signal (2006) 1.05
Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling. Proc Natl Acad Sci U S A (2012) 1.05
K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharmacol (2012) 1.04
The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation. J Immunol (2014) 1.04
Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties. Biochim Biophys Acta (2008) 1.04
A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging. PLoS One (2008) 1.02
Metabolic consequences of ENPP1 overexpression in adipose tissue. Am J Physiol Endocrinol Metab (2011) 1.00
Specific requirements for Vgamma9Vdelta2 T cell stimulation by a natural adenylated phosphoantigen. J Immunol (2009) 0.98
Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks. Purinergic Signal (2006) 0.96
The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis. Appl Clin Genet (2014) 0.96
Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily. Biochemistry (2008) 0.93
Mechanisms of induction of adenosine receptor genes and its functional significance. J Cell Physiol (2009) 0.92
Measurement of purine release with microelectrode biosensors. Purinergic Signal (2011) 0.92
γδ T cell receptor ligands and modes of antigen recognition. Arch Immunol Ther Exp (Warsz) (2011) 0.91
Purinergic receptors and nucleotide processing ectoenzymes: Their roles in regulating mesenchymal stem cell functions. World J Stem Cells (2014) 0.89
Dexamethasone enhances ATP-induced inflammatory responses in endothelial cells. J Pharmacol Exp Ther (2010) 0.89
Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis. Int J Oral Sci (2015) 0.88
Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation. J Clin Invest (2014) 0.87
Expression of plasma cell alloantigen 1 defines layered development of B-1a B-cell subsets with distinct innate-like functions. Proc Natl Acad Sci U S A (2012) 0.87
Metabolism of circulating ADP in the bloodstream is mediated via integrated actions of soluble adenylate kinase-1 and NTPDase1/CD39 activities. FASEB J (2012) 0.87
Assessing basophil activation by using flow cytometry and mass cytometry in blood stored 24 hours before analysis. J Allergy Clin Immunol (2016) 0.84
Identification of ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) as a regulator of N-acetylglucosaminyltransferase GnT-IX (GnT-Vb). J Biol Chem (2013) 0.83
Ectonucleotidases in tumor cells and tumor-associated immune cells: an overview. J Biomed Biotechnol (2012) 0.83
Inflammation, pain, and pressure--purinergic signaling in oral tissues. J Dent Res (2012) 0.82
Transcriptional analysis of a unique set of genes involved in Schistosoma mansoni female reproductive biology. PLoS Negl Trop Dis (2012) 0.82
The CD39-adenosinergic axis in the pathogenesis of renal ischemia-reperfusion injury. Purinergic Signal (2012) 0.82
Characterization of ectonucleotidases in human medulloblastoma cell lines: ecto-5'NT/CD73 in metastasis as potential prognostic factor. PLoS One (2012) 0.81
Regulation of allergic inflammation by the ectoenzyme E-NPP3 (CD203c) on basophils and mast cells. Semin Immunopathol (2016) 0.80
Cole Disease Results from Mutations in ENPP1. Am J Hum Genet (2013) 0.80
Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression. J Lipid Res (2015) 0.80
Adenosine and immune imbalance in visceral leishmaniasis: the possible role of ectonucleotidases. J Trop Med (2011) 0.80
Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD). Virchows Arch (2007) 0.79
Characterization of monoclonal antibodies to the plasma cell alloantigen ENPP1. Hybridoma (Larchmt) (2011) 0.79
Cloning, expression, and characterization of Schistosoma japonicum tegument protein phosphodiesterase-5. Parasitol Res (2011) 0.79
Adenosine and blood platelets. Purinergic Signal (2011) 0.79
Antiplatelet activity, P2Y₁ and P2Y₁₂ inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'″-P¹ ,P⁴-dithio-P²,P³-chloromethylenetetraphosphate. PLoS One (2014) 0.79
The venomous cocktail of the vampire snail Colubraria reticulata (Mollusca, Gastropoda). BMC Genomics (2015) 0.78
Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryot Cell (2005) 0.78
8-BuS-ATP derivatives as specific NTPDase1 inhibitors. Br J Pharmacol (2013) 0.77
Gene Expression Profiling in Peripheral Blood Cells and Synovial Membranes of Patients with Psoriatic Arthritis. PLoS One (2015) 0.76
Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1. Front Microbiol (2016) 0.76
Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells. Br J Pharmacol (2015) 0.76
Systems Genetics Approach Identifies Gene Pathways and Adamts2 as Drivers of Isoproterenol-Induced Cardiac Hypertrophy and Cardiomyopathy in Mice. Cell Syst (2016) 0.76
Expression and regulation of Enpp2 in rat uterus during the estrous cycle. J Vet Sci (2011) 0.76
Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily. J Am Chem Soc (2016) 0.75
Integrated electroosmotic perfusion of tissue with online microfluidic analysis to track the metabolism of cystamine, pantethine, and coenzyme A. Anal Chem (2013) 0.75
E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine. PLoS One (2017) 0.75
Computational identification and experimental characterization of substrate binding determinants of nucleotide pyrophosphatase/phosphodiesterase 7. BMC Biochem (2011) 0.75
Some aspects of purinergic signaling in the ventricular system of porcine brain. Acta Vet Scand (2011) 0.75
Ectonucleotidases in solid organ and allogeneic hematopoietic cell transplantation. J Biomed Biotechnol (2012) 0.75
Genetics Underlying an Individualized Approach to Adult Spinal Disorders. Front Surg (2016) 0.75
ENPP1 and ESR1 genotypes influence temporomandibular disorders development and surgical treatment response in dentofacial deformities. J Craniomaxillofac Surg (2016) 0.75
IL15RA is required for osteoblast function and bone mineralization. Bone (2017) 0.75
Rat C6 glioma as experimental model system for the study of glioblastoma growth and invasion. Cell Tissue Res (2002) 1.91
Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks. Purinergic Signal (2006) 0.96
P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1. Cell Signal (2005) 0.89
P2Y12 receptor stimulation inhibits beta-adrenergic receptor-induced differentiation by reversing the cyclic AMP-dependent inhibition of protein kinase B. J Neurochem (2004) 0.83
The expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (E-NPP1) is correlated with astrocytic tumor grade. Clin Neurol Neurosurg (2010) 0.82
Extracellular nucleoside diphosphate kinase NM23/NDPK modulates normal hematopoietic differentiation. Exp Hematol (2002) 0.79
Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells. FEBS J (2006) 0.78
Reactive blue 2 inhibition of cyclic AMP-dependent differentiation of rat C6 glioma cells by purinergic receptor-independent inactivation of phosphatidylinositol 3-kinase. Biochem Pharmacol (2004) 0.77
Influence of ionic and non-ionic radiographic contrast media on leukocyte adhesion molecules. Mediators Inflamm (2003) 0.75
Investigation of the use of immobilised metal affinity chromatography for the on-line sample clean up and pre-concentration of nucleotides prior to their determination by ion pair liquid chromatography-electrospray mass spectrometry: a pilot study. J Chromatogr B Analyt Technol Biomed Life Sci (2004) 0.75
Cyclic AMP-dependent down regulation of ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) in rat C6 glioma. Eur J Pharmacol (2010) 0.75