Published in Oncogene on May 22, 2003
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Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science (2008) 3.80
PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect. Nat Med (2003) 2.97
Male pheromone-stimulated neurogenesis in the adult female brain: possible role in mating behavior. Nat Neurosci (2007) 2.55
(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. J Biol Chem (2005) 1.99
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FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (2010) 1.86
Male hormonal contraception: a double-blind, placebo-controlled study. J Clin Endocrinol Metab (2008) 1.79
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Increased carotid atherosclerosis in andropausal middle-aged men. J Am Coll Cardiol (2005) 1.70
Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles. Hum Mol Genet (2009) 1.58
The transcriptional corepressor RIP140 regulates oxidative metabolism in skeletal muscle. Cell Metab (2007) 1.54
FOXA1: a transcription factor with parallel functions in development and cancer. Biosci Rep (2012) 1.52
Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation. Proc Natl Acad Sci U S A (2010) 1.50
Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor. Fertil Steril (2002) 1.48
Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J Clin Invest (2011) 1.46
Human HSD17B1 expression masculinizes transgenic female mice. Mol Cell Endocrinol (2008) 1.46
Cell cycle correlated genes dictate the prognostic power of breast cancer gene lists. BMC Med Genomics (2008) 1.43
Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation. Biol Reprod (2011) 1.42
The androgen and progesterone receptors regulate distinct gene networks and cellular functions in decidualizing endometrium. Endocrinology (2008) 1.42
Krüppel-like factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia (2011) 1.39
Polymorphisms in androgen and estrogen receptor genes: effects on male aging. Exp Gerontol (2004) 1.39
Angiogenic activity of human chorionic gonadotropin through LH receptor activation on endothelial and epithelial cells of the endometrium. FASEB J (2006) 1.29
PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles. Hum Mol Genet (2009) 1.28
HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. J Biol Chem (2010) 1.24
Follicle-stimulating hormone/cAMP regulation of aromatase gene expression requires beta-catenin. Proc Natl Acad Sci U S A (2006) 1.18
Assisted large fragment insertion by Red/ET-recombination (ALFIRE)--an alternative and enhanced method for large fragment recombineering. Nucleic Acids Res (2007) 1.17
The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression. J Biol Chem (2012) 1.15
Multiple and overlapping combinatorial codes orchestrate hormonal responsiveness and dictate cell-specific expression of the genes encoding luteinizing hormone. Endocr Rev (2004) 1.13
The diversity of sex steroid action: novel functions of hydroxysteroid (17β) dehydrogenases as revealed by genetically modified mouse models. J Endocrinol (2011) 1.13
Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G). Mol Pharmacol (2005) 1.13
Enhanced delivery of chemotherapy to tumors using a multicomponent nanochain with radio-frequency-tunable drug release. ACS Nano (2012) 1.12
Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice. Endocrinology (2003) 1.12
Conditional deletion of beta-catenin mediated by Amhr2cre in mice causes female infertility. Biol Reprod (2009) 1.11
Discovery in silico and characterization in vitro of novel genes exclusively expressed in the mouse epididymis. Mol Endocrinol (2003) 1.10
Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive azoospermia. Endocrinology (2010) 1.09
Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin. Endocrinology (2002) 1.09
Human homologs of the putative G protein-coupled membrane progestin receptors (mPRalpha, beta, and gamma) localize to the endoplasmic reticulum and are not activated by progesterone. Mol Endocrinol (2006) 1.08
Myosin II isoform switching mediates invasiveness after TGF-β-induced epithelial-mesenchymal transition. Proc Natl Acad Sci U S A (2011) 1.07
Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice. Mol Cell Biol (2003) 1.07
Lhcgr expression in granulosa cells: roles for PKA-phosphorylated β-catenin, TCF3, and FOXO1. Mol Endocrinol (2013) 1.06
Bisphenol A increases mammary cancer risk in two distinct mouse models of breast cancer. Biol Reprod (2011) 1.06
Elevated steroidogenesis, defective reproductive organs, and infertility in transgenic male mice overexpressing human chorionic gonadotropin. Endocrinology (2003) 1.05
Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. Mol Cancer Ther (2007) 1.05
A Novel mutation in the FSH receptor inhibiting signal transduction and causing primary ovarian failure. J Clin Endocrinol Metab (2002) 1.05
Maximal activity of the luteinizing hormone beta-subunit gene requires beta-catenin. Mol Endocrinol (2007) 1.04
Gene expression profiling of cancer progression reveals intrinsic regulation of transforming growth factor-beta signaling in ErbB2/Neu-induced tumors from transgenic mice. Oncogene (2005) 1.04
Novel concepts of human chorionic gonadotropin: reproductive system interactions and potential in the management of infertility. Fertil Steril (2005) 1.04
Imaging metastasis using an integrin-targeting chain-shaped nanoparticle. ACS Nano (2012) 1.03
A fluorescent Tie1 reporter allows monitoring of vascular development and endothelial cell isolation from transgenic mouse embryos. FASEB J (2002) 1.02
The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. Proc Natl Acad Sci U S A (2003) 1.01
Increased exposure to estrogens disturbs maturation, steroidogenesis, and cholesterol homeostasis via estrogen receptor alpha in adult mouse Leydig cells. Endocrinology (2009) 1.01
Differential effects of estrogen/androgen on the prevention of nonalcoholic fatty liver disease in the male rat. J Lipid Res (2012) 1.00
Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice. Endocrinology (2004) 1.00
Dicer1 ablation in the mouse epididymis causes dedifferentiation of the epithelium and imbalance in sex steroid signaling. PLoS One (2012) 0.99
The HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression. Mol Cancer Res (2013) 0.99
GATA-4 regulates Bcl-2 expression in ovarian granulosa cell tumors. Endocrinology (2008) 0.98
Inactivation of estrogen receptor α in bone-forming cells induces bone loss in female mice. FASEB J (2012) 0.98
Common respiratory infections early in life may reduce the risk of atopic dermatitis. Clin Infect Dis (2002) 0.98
Mouse models of infertility due to swollen spermatozoa. Mol Cell Endocrinol (2004) 0.98
Epididymal dysfunction initiated by the expression of simian virus 40 T-antigen leads to angulated sperm flagella and infertility in transgenic mice. Mol Endocrinol (2002) 0.98
Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta. Endocrinology (2004) 0.97
Sperm volume regulation: maturational changes in fertile and infertile transgenic mice and association with kinematics and tail angulation. Biol Reprod (2002) 0.97
Aging of the human ovary and testis. Mol Cell Endocrinol (2008) 0.96
Increases in luteinizing hormone are associated with declines in cognitive performance. Mol Cell Endocrinol (2007) 0.96
Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse graafian follicles. Mol Endocrinol (2005) 0.96
Endometrial and endometriotic concentrations of estrone and estradiol are determined by local metabolism rather than circulating levels. J Clin Endocrinol Metab (2012) 0.95
Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein. J Biol Chem (2013) 0.95
Female mice carrying a ubiquitin promoter-Insl3 transgene have descended ovaries and inguinal hernias but normal fertility. Mol Cell Endocrinol (2003) 0.94
Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice. Neoplasia (2010) 0.94
Welcoming beta-catenin to the gonadotropin-releasing hormone transcriptional network in gonadotropes. Mol Endocrinol (2008) 0.94
Reexpression of p8 contributes to tumorigenic properties of pituitary cells and appears in a subset of prolactinomas in transgenic mice that hypersecrete luteinizing hormone. Mol Endocrinol (2004) 0.94
Bmx tyrosine kinase transgene induces skin hyperplasia, inflammatory angiogenesis, and accelerated wound healing. Mol Biol Cell (2004) 0.94
Is the adrenal cortex a target for gonadotropins? Trends Endocrinol Metab (2008) 0.93
Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects. J Bone Miner Res (2009) 0.93
Human FSH beta subunit gene is highly conserved. Mol Hum Reprod (2005) 0.93
Biodistribution and clearance of a filamentous plant virus in healthy and tumor-bearing mice. Nanomedicine (Lond) (2013) 0.92
Both testosterone and follicle-stimulating hormone independently inhibit spermatogonial differentiation in irradiated rats. Endocrinology (2005) 0.92
What have gonadotrophin overexpressing transgenic mice taught us about gonadal function? Reproduction (2005) 0.92
Hyperglycosylated human chorionic gonadotropin stimulates angiogenesis through TGF-β receptor activation. FASEB J (2012) 0.92
Improved statistical modeling of tumor growth and treatment effect in preclinical animal studies with highly heterogeneous responses in vivo. Clin Cancer Res (2012) 0.92
Functional characterization of the human FSH receptor with an inactivating Ala189Val mutation. Mol Hum Reprod (2002) 0.92
Human chorionic gonadotropin (hCG) up-regulates wnt5b and wnt7b in the mammary gland, and hCGbeta transgenic female mice present with mammary Gland tumors exhibiting characteristics of the Wnt/beta-catenin pathway activation. Endocrinology (2007) 0.92
Mouse cysteine-rich secretory protein 4 (CRISP4): a member of the Crisp family exclusively expressed in the epididymis in an androgen-dependent manner. Biol Reprod (2005) 0.91