Jacques H van Boom

Author PubWeight™ 24.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides. Org Lett 2003 1.42
2 Biochemical and genetic studies of the VPg uridylylation reaction catalyzed by the RNA polymerase of poliovirus. J Virol 2003 1.37
3 A modular strategy toward the synthesis of heparin-like oligosaccharides using monomeric building blocks in a sequential glycosylation strategy. J Am Chem Soc 2005 1.17
4 Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. J Biol Chem 2003 1.16
5 Recognition of base J in duplex DNA by J-binding protein. J Biol Chem 2001 1.15
6 The conformation of neurotensin bound to its G protein-coupled receptor. Proc Natl Acad Sci U S A 2003 1.14
7 Thioglycuronides: synthesis and application in the assembly of acidic oligosaccharides. Org Lett 2004 1.11
8 Sequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors. Org Lett 2003 0.94
9 The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system. Nucleic Acids Res 2002 0.89
10 Surface plasmon resonance evaluation of various aminoglycoside-RNA hairpin interactions reveals low degree of selectivity. Chembiochem 2004 0.85
11 Site-specific interactions of JBP with base and sugar moieties in duplex J-DNA. Evidence for both major and minor groove contacts. J Biol Chem 2002 0.84
12 1,3-Dimethyllumazine derivatives from Limnatis nilotica. J Nat Prod 2005 0.84
13 Synthesis and elaboration of functionalised carbohydrate-derived spiroketals. Org Biomol Chem 2004 0.83
14 Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen. Structure 2004 0.82
15 Synthesis and biological evaluation of novel turn-modified gramicidin S analogues. Bioorg Med Chem 2003 0.82
16 Effect of bulky lesions on DNA: solution structure of a DNA duplex containing a cholesterol adduct. J Biol Chem 2004 0.81
17 A novel strategy towards the synthesis of orthogonally functionalised 4-aminoglycosides. Org Biomol Chem 2003 0.80
18 Synthesis and in vitro evaluation of PNA-peptide-DETA conjugates as potential cell penetrating artificial ribonucleases. Bioconjug Chem 2004 0.80
19 Peptidomimetic glutathione analogues as novel gammaGT stable GST inhibitors. Bioorg Med Chem 2002 0.79
20 A short route toward chiral, polyhydroxylated indolizidines and quinolizidines. J Org Chem 2003 0.79
21 Automated parallel solid-phase synthesis and anticancer screening of a library of peptide-tethered platinum(II) complexes. J Comb Chem 2003 0.78
22 Confirmation of the D configuration of the 2-substituted arabinitol 1-phosphate residue in the capsular polysaccharide from Streptococcus pneumoniae Type 17F. Carbohydr Res 2002 0.78
23 The beta-glucuronyl-based prodrug strategy allows for its application on beta-glucuronyl-platinum conjugates. Bioorg Med Chem Lett 2004 0.78
24 Monofunctionally trans-diammine platinum(II)-modified peptide nucleic acid oligomers: a new generation of potential antisense drugs. Chemistry 2002 0.78
25 The interaction of peptide-tethered platinum(II) complexes with DNA. J Inorg Biochem 2003 0.77
26 A targeted peptide nucleic acid to down-regulate mouse microsomal triglyceride transfer protein expression in hepatocytes. Bioconjug Chem 2003 0.77
27 A versatile approach towards regioselective platinated DNA sequences. Chemistry 2003 0.77
28 Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids. Nucleic Acids Res 2002 0.75
29 Improvement of hepatocyte-specific gene expression by a targeted colchicine prodrug. Chembiochem 2003 0.75
30 The use of a mannitol-derived fused oxacycle as a combinatorial scaffold. J Org Chem 2003 0.75
31 Effective, high-yielding, and stereospecific total synthesis of D-erythro-(2R,3S)-sphingosine from D-ribo-(2S,3S,4R)-phytosphingosine. J Org Chem 2004 0.75
32 Conformational analysis of furanoid epsilon-sugar amino acid containing cyclic peptides by NMR spectroscopy, molecular dynamics simulation, and X-ray crystallography: evidence for a novel turn structure. J Am Chem Soc 2003 0.75
33 Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal beta-hexosaminidases. Bioorg Med Chem 2004 0.75
34 A practical synthesis of gramicidin s and sugar amino Acid containing analogues. J Org Chem 2004 0.75
35 Chemically synthesized protein as tumour-specific vaccine: immunogenicity and efficacy of synthetic HPV16 E7 in the TC-1 mouse tumour model. Vaccine 2004 0.75
36 Solid-phase synthesis of cyclic RGD-furanoid sugar amino acid peptides as integrin inhibitors. Bioorg Med Chem Lett 2003 0.75
37 Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1. J Med Chem 2004 0.75