Published in Diabetes on June 01, 2003
Periodontitis and diabetes: a two-way relationship. Diabetologia (2011) 2.27
Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues. Am J Physiol Endocrinol Metab (2005) 1.86
Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications. Ann N Y Acad Sci (2011) 1.60
Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone (2006) 1.44
Diabetic periodontitis: a model for activated innate immunity and impaired resolution of inflammation. Periodontol 2000 (2007) 1.08
FOXO1 plays an essential role in apoptosis of retinal pericytes. Mol Vis (2010) 1.04
Type I diabetic bone phenotype is location but not gender dependent. Histochem Cell Biol (2007) 1.00
STR/ort mice, a model for spontaneous osteoarthritis, exhibit elevated levels of both local and systemic inflammatory markers. Comp Med (2011) 0.95
Inflammation as death or life signal in diabetic fracture healing. Inflamm Res (2010) 0.93
Spontaneous periodontitis development in diabetic rats involves an unrestricted expression of inflammatory cytokines and tissue destructive factors in the absence of major changes in commensal oral microbiota. Exp Diabetes Res (2012) 0.91
Cells and tissue interactions with glycated collagen and their relevance to delayed diabetic wound healing. Biomaterials (2009) 0.91
Proinsulin C-peptide regulates ribosomal RNA expression. J Biol Chem (2009) 0.90
Collagen advanced glycation inhibits its Discoidin Domain Receptor 2 (DDR2)-mediated induction of lysyl oxidase in osteoblasts. Bone (2013) 0.89
Diabetes mellitus related bone metabolism and periodontal disease. Int J Oral Sci (2015) 0.88
Receptor for advanced glycation endproducts mediates pro-atherogenic responses to periodontal infection in vascular endothelial cells. Atherosclerosis (2010) 0.85
RAGE and its ligands in bone metabolism. Front Biosci (Schol Ed) (2011) 0.83
Arthroplasty in veterans: analysis of cartilage, bone, serum, and synovial fluid reveals differences and similarities in osteoarthritis with and without comorbid diabetes. J Rehabil Res Dev (2011) 0.83
Application of VEGFA and FGF-9 enhances angiogenesis, osteogenesis and bone remodeling in type 2 diabetic long bone regeneration. PLoS One (2015) 0.81
Molecular mechanisms involved in the bidirectional relationship between diabetes mellitus and periodontal disease. J Indian Soc Periodontol (2013) 0.81
The influence of diabetes mellitus on periodontal tissues: a pilot study. J Periodontal Implant Sci (2010) 0.80
Repair process of surgical defects filled with autogenous bone grafts in tibiae of diabetic rats. J Appl Oral Sci (2008) 0.79
Pathophysiological role of enhanced bone marrow adipogenesis in diabetic complications. Adipocyte (2014) 0.78
Dental implant survival in diabetic patients; review and recommendations. Natl J Maxillofac Surg (2013) 0.78
Rehabilitative considerations for dental implants in the diabetic patient. J Indian Prosthodont Soc (2012) 0.77
Augmented LPS responsiveness in type 1 diabetes-derived osteoclasts. J Cell Physiol (2013) 0.77
Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy. ACS Biomater Sci Eng (2016) 0.76
Chronic Kidney Disease Impairs Bone Defect Healing in Rats. Sci Rep (2016) 0.76
In vitro culture and characterization of alveolar bone osteoblasts isolated from type 2 diabetics. Braz J Med Biol Res (2012) 0.76
Diabetes-induced fibrotic matrix inhibits intramembranous bone healing. J Cell Commun Signal (2014) 0.76
Effects of Type 1 Diabetes on Osteoblasts, Osteocytes, and Osteoclasts. Curr Osteoporos Rep (2016) 0.75
Diabetes and bone health: latest evidence and clinical implications. Ther Adv Musculoskelet Dis (2017) 0.75
Constructing the toolbox: Patient-specific genetic factors of altered fracture healing. Genes Dis (2014) 0.75
Histologic effects of demineralized bone matrix on regeneration of alveolar socket in diabetic rats. Iran Endod J (2009) 0.75
Effect of targeted delivery of bone morphogenetic protein-2 on bone formation in type 1 diabetes. Int J Oral Maxillofac Implants (2015) 0.75
Complication rates in diabetics with first metatarsophalangeal joint arthrodesis. Diabet Foot Ankle (2014) 0.75
Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. Stem Cell Res Ther (2017) 0.75
Evaluation of stability of surface-treated mini-implants in diabetic rabbits. Int J Dent (2014) 0.75
The effects of diabetes medications on post-operative long bone fracture healing. Eur J Orthop Surg Traumatol (2015) 0.75
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell (2004) 8.78
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev (2011) 5.64
Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem (2003) 4.34
Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet (2013) 3.83
Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature (2002) 3.40
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol (2006) 3.37
Simple decision rules for classifying human cancers from gene expression profiles. Bioinformatics (2005) 3.24
Efficacy and safety of sitagliptin in patients with type 2 diabetes and ESRD receiving dialysis: a 54-week randomized trial. Am J Kidney Dis (2013) 2.89
Induction of angiogenesis in a mouse model using engineered transcription factors. Nat Med (2002) 2.81
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell (2013) 2.64
CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? Clin Cancer Res (2011) 2.39
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature (2004) 2.22
Porphyromonas gingivalis infection accelerates the progression of atherosclerosis in a heterozygous apolipoprotein E-deficient murine model. Circulation (2002) 2.16
miRDeepFinder: a miRNA analysis tool for deep sequencing of plant small RNAs. Plant Mol Biol (2012) 2.14
BSMART: a Matlab/C toolbox for analysis of multichannel neural time series. Neural Netw (2008) 2.14
Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ Res (2003) 2.12
Obesity, tamoxifen use, and outcomes in women with estrogen receptor-positive early-stage breast cancer. J Natl Cancer Inst (2003) 2.11
Deep sequencing of the oral microbiome reveals signatures of periodontal disease. PLoS One (2012) 1.96
GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci (2008) 1.93
A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples. Anal Biochem (2002) 1.84
Interleukin-1 receptor signaling mediates atherosclerosis associated with bacterial exposure and/or a high-fat diet in a murine apolipoprotein E heterozygote model: pharmacotherapeutic implications. Circulation (2004) 1.82
Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine. Biomaterials (2012) 1.81
Cytokine profiling of macrophages exposed to Porphyromonas gingivalis, its lipopolysaccharide, or its FimA protein. Infect Immun (2005) 1.77
A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflamm Bowel Dis (2006) 1.69
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing. J Bone Miner Res (2009) 1.68
Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity. J Bone Miner Res (2007) 1.67
NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. J Clin Invest (2005) 1.65
Efficacy and safety of sitagliptin in the treatment of patients with type 2 diabetes in China, India, and Korea. Diabetes Res Clin Pract (2008) 1.65
FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. J Biol Chem (2005) 1.63
Association of serum uric acid level with non-alcoholic fatty liver disease: a cross-sectional study. J Hepatol (2009) 1.62
Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am J Pathol (2008) 1.61
Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis. Cancer Res (2006) 1.60
Enhanced chondrogenesis and Wnt signaling in PTH-treated fractures. J Bone Miner Res (2007) 1.59
Association between thyroid function and nonalcoholic fatty liver disease in euthyroid elderly Chinese. Clin Endocrinol (Oxf) (2011) 1.59
Perivascular nitric oxide gradients normalize tumor vasculature. Nat Med (2008) 1.56
Statins, autophagy and cancer metastasis. Int J Biochem Cell Biol (2012) 1.56
Periodontal disease and systemic conditions: a bidirectional relationship. Odontology (2006) 1.52
TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proc Natl Acad Sci U S A (2012) 1.51
Three-dimensional reconstruction of fracture callus morphogenesis. J Histochem Cytochem (2006) 1.48
The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. J Biol Chem (2004) 1.47
Genetically encoded fluorescent sensors for intracellular NADH detection. Cell Metab (2011) 1.47
Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone (2006) 1.44
The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. Cancer Res (2007) 1.41
Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differentiation. Endocrinology (2003) 1.41
Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones. PLoS Pathog (2009) 1.41
The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells. J Biol Chem (2008) 1.41
Diabetes prolongs the inflammatory response to a bacterial stimulus through cytokine dysregulation. J Invest Dermatol (2004) 1.40
LPS-induced TNF-alpha factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways. Proc Natl Acad Sci U S A (2006) 1.40
Hereditary gingival fibromatosis associated with generalized aggressive periodontitis: a case report. J Periodontol (2004) 1.36
Technical reproducibility of genotyping SNP arrays used in genome-wide association studies. PLoS One (2012) 1.36
Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma. Tumour Biol (2014) 1.32
Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells. Toxicology (2007) 1.31
Repression of BCL2 by the tumor suppressor activity of the lysyl oxidase propeptide inhibits transformed phenotype of lung and pancreatic cancer cells. Cancer Res (2007) 1.31
Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1. J Biol Chem (2011) 1.31
LPS induces the interaction of a transcription factor, LPS-induced TNF-alpha factor, and STAT6(B) with effects on multiple cytokines. Proc Natl Acad Sci U S A (2005) 1.29
Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes. Cell (2002) 1.29
Identification and functional characterization of a novel binding site on TNF-alpha promoter. Proc Natl Acad Sci U S A (2003) 1.28
Role of forkhead transcription factors in diabetes-induced oxidative stress. Exp Diabetes Res (2012) 1.27
Metabolic network model of a human oral pathogen. J Bacteriol (2008) 1.26
CCN2, connective tissue growth factor, stimulates collagen deposition by gingival fibroblasts via module 3 and alpha6- and beta1 integrins. J Cell Biochem (2006) 1.26
Tumor necrosis factor-alpha mediates diabetes-enhanced apoptosis of matrix-producing cells and impairs diabetic healing. Am J Pathol (2006) 1.25
FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats. Diabetes (2009) 1.25
Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. Endocrinology (2003) 1.25
Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses. Proc Natl Acad Sci U S A (2009) 1.25
FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress. J Cell Biol (2013) 1.22
Identification of signaling pathways in macrophage exposed to Porphyromonas gingivalis or to its purified cell wall components. J Immunol (2007) 1.22
High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing. Am J Pathol (2009) 1.20
High serum uric acid increases the risk for nonalcoholic Fatty liver disease: a prospective observational study. PLoS One (2010) 1.19
Comparative genomics of the core and accessory genomes of 48 Sinorhizobium strains comprising five genospecies. Genome Biol (2013) 1.18
Modeling the epidemiological history of plague in Central Asia: palaeoclimatic forcing on a disease system over the past millennium. BMC Biol (2010) 1.18
A quantitative comparison of the influence of individual versus population-derived vascular input functions on dynamic contrast enhanced-MRI in small animals. Magn Reson Med (2011) 1.18
Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways. J Biol Chem (2004) 1.18
Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP. Hum Mol Genet (2013) 1.17
Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor. Am J Physiol Cell Physiol (2006) 1.16
Morphometric, histomorphometric, and microcomputed tomographic analysis of periodontal inflammatory lesions in a murine model. J Periodontol (2007) 1.15
Toll-like receptor-2 mediates diet and/or pathogen associated atherosclerosis: proteomic findings. PLoS One (2008) 1.15
A novel AIF tracking method and comparison of DCE-MRI parameters using individual and population-based AIFs in human breast cancer. Phys Med Biol (2011) 1.15
A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer. Cancer Res (2009) 1.14
Ultrafast synaptic events in a chalcogenide memristor. Sci Rep (2013) 1.14
Differential vascular and transcriptional responses to anti-vascular endothelial growth factor antibody in orthotopic human pancreatic cancer xenografts. Clin Cancer Res (2003) 1.14
Diabetes alters the response to bacteria by enhancing fibroblast apoptosis. Endocrinology (2004) 1.12
Prevalence and risk factors for the development of nonalcoholic fatty liver disease in a nonobese Chinese population: the Zhejiang Zhenhai Study. Am J Gastroenterol (2013) 1.12
A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures. J Cell Physiol (2004) 1.11
Activation of the acquired immune response reduces coupled bone formation in response to a periodontal pathogen. J Immunol (2008) 1.11
GPR56 Regulates VEGF production and angiogenesis during melanoma progression. Cancer Res (2011) 1.11
TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1. J Bone Miner Res (2010) 1.11
Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. Bone (2008) 1.10
Lysyl oxidase propeptide inhibits smooth muscle cell signaling and proliferation. Biochem Biophys Res Commun (2007) 1.10
Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China. Vet Microbiol (2009) 1.10
Inflammation and tissue loss caused by periodontal pathogens is reduced by interleukin-1 antagonists. J Infect Dis (2002) 1.10
Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes. J Leukoc Biol (2006) 1.10