A multi-center 1H MRS study of the AIDS dementia complex: validation and preliminary analysis.

PubWeight™: 1.34‹?› | Rank: Top 10%

🔗 View Article (PMID 12766890)

Published in J Magn Reson Imaging on June 01, 2003

Authors

Patricia Lani Lee1, Constantin T Yiannoutsos, Thomas Ernst, Linda Chang, Christina M Marra, Jeffrey G Jarvik, Todd L Richards, Edmund W Kwok, Dennis L Kolson, David Simpson, Cheuk Y Tang, Giovanni Schifitto, Leena M Ketonen, Dieter J Meyerhoff, Robert E Lenkinski, R Gilberto Gonzalez, Bradford A Navia, HIV MRS Consortium

Author Affiliations

1: NMR Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02111, USA. bnavia@lifespan.org

Articles citing this

Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection. Neurology (2009) 2.08

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. AIDS (2011) 2.04

Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS. J Clin Invest (2005) 1.78

Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals. J Neurovirol (2011) 1.31

Multisite neuroimaging trials. Curr Opin Neurol (2009) 1.25

Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes. J Neurovirol (2010) 1.22

In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain. BMC Neurosci (2009) 1.16

HIV, vascular and aging injuries in the brain of clinically stable HIV-infected adults: a (1)H MRS study. PLoS One (2013) 1.11

A prospective longitudinal in vivo 1H MR spectroscopy study of the SIV/macaque model of neuroAIDS. BMC Neurosci (2004) 1.08

Minocycline treatment for HIV-associated cognitive impairment: results from a randomized trial. Neurology (2011) 1.07

Disrupted cerebral metabolite levels and lower nadir CD4 + counts are linked to brain volume deficits in 210 HIV-infected patients on stable treatment. Neuroimage Clin (2013) 1.01

Two-site reproducibility of cerebellar and brainstem neurochemical profiles with short-echo, single-voxel MRS at 3T. Magn Reson Med (2014) 0.96

IFN-alpha-induced cortical and subcortical glutamate changes assessed by magnetic resonance spectroscopy. Neuropsychopharmacology (2014) 0.96

Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy. J Neurovirol (2013) 0.95

Neuronal injury in simian immunodeficiency virus and other animal models of neuroAIDS. J Neurovirol (2008) 0.91

Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment. AIDS (2014) 0.90

A multicenter reproducibility study of single-voxel 1H-MRS of the medial temporal lobe. Eur Radiol (2006) 0.89

Automatic repositioning of MRSI voxels in longitudinal studies: impact on reproducibility of metabolite concentration measurements. J Magn Reson Imaging (2008) 0.89

Plasma and Cerebrospinal Fluid Biomarkers Predict Cerebral Injury in HIV-Infected Individuals on Stable Combination Antiretroviral Therapy. J Acquir Immune Defic Syndr (2015) 0.87

Methamphetamine abuse, HIV infection, and neurotoxicity. Int J Physiol Pathophysiol Pharmacol (2009) 0.87

Quantitative proton magnetic resonance spectroscopy and spectroscopic imaging of the brain: a didactic review. Top Magn Reson Imaging (2010) 0.84

Magnetic resonance spectroscopy as an early indicator of response to anti-angiogenic therapy in patients with recurrent glioblastoma: RTOG 0625/ACRIN 6677. Neuro Oncol (2013) 0.83

Assessing multiple-group diagnostic problems with multi-dimensional receiver operating characteristic surfaces: application to proton MR Spectroscopy (MRS) in HIV-related neurological injury. Neuroimage (2007) 0.82

Predictors of CNS injury as measured by proton magnetic resonance spectroscopy in the setting of chronic HIV infection and CART. J Neurovirol (2014) 0.82

Hippocampal MR spectroscopic abnormalities in a cohort of syphilitic patients with HIV and neurosyphilis infection. Am J Nucl Med Mol Imaging (2014) 0.77

Improved myo-inositol detection through Carr-Purcell PRESS: a tool for more sensitive mild cognitive impairment diagnosis. Magn Reson Med (2011) 0.77

Biochemical changes in the cingulum in patients with schizophrenia and chronic bipolar disorder. Eur Arch Psychiatry Clin Neurosci (2008) 0.76

The role of medical imaging in defining CNS abnormalities associated with HIV-infection and opportunistic infections. Neurotherapeutics (2011) 0.75

Reproducibility of brain metabolite concentration measurements in lesion free white matter at 1.5 T. BMC Med Imaging (2015) 0.75

HMGB1/anti-HMGB1 antibodies define a molecular signature of early stages of HIV-Associated Neurocognitive Isorders (HAND). Heliyon (2017) 0.75

Articles by these authors

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet (2011) 13.10

A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med (2009) 10.06

Viability and effectiveness of large-scale HIV treatment initiatives in sub-Saharan Africa: experience from western Kenya. AIDS (2006) 7.99

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors. J Neurovirol (2010) 7.56

Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults. JAMA (2010) 7.28

Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol (2008) 6.91

Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood (2005) 6.05

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia. N Engl J Med (2015) 5.69

Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial. Lancet (2010) 5.59

Major medical outcomes with spinal augmentation vs conservative therapy. JAMA Intern Med (2013) 5.58

A randomized trial of epidural glucocorticoid injections for spinal stenosis. N Engl J Med (2014) 5.01

PARACEST agents: modulating MRI contrast via water proton exchange. Acc Chem Res (2003) 4.44

Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: four-year results of a prospective phase II study. Int J Radiat Oncol Biol Phys (2009) 4.23

HIV-associated cognitive impairment before and after the advent of combination therapy. J Neurovirol (2002) 4.20

Understanding reasons for and outcomes of patients lost to follow-up in antiretroviral therapy programs in Africa through a sampling-based approach. J Acquir Immune Defic Syndr (2010) 4.20

Retention in care among HIV-infected patients in resource-limited settings: emerging insights and new directions. Curr HIV/AIDS Rep (2010) 3.80

The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis (2008) 3.79

Effectiveness of vertebroplasty using individual patient data from two randomised placebo controlled trials: meta-analysis. BMJ (2011) 3.69

Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms. Blood (2009) 3.69

Macrolide resistance in Treponema pallidum in the United States and Ireland. N Engl J Med (2004) 3.54

Immune surveillance in multiple sclerosis patients treated with natalizumab. Ann Neurol (2006) 3.38

Is decreased prefrontal cortical sensitivity to monetary reward associated with impaired motivation and self-control in cocaine addiction? Am J Psychiatry (2007) 3.33

Update on syphilis: resurgence of an old problem. JAMA (2003) 3.31

BCR-ABL kinase domain mutation analysis in chronic myeloid leukemia patients treated with tyrosine kinase inhibitors: recommendations from an expert panel on behalf of European LeukemiaNet. Blood (2011) 3.02

Age-related total gray matter and white matter changes in normal adult brain. Part I: volumetric MR imaging analysis. AJNR Am J Neuroradiol (2002) 2.94

Continued high prevalence and adverse clinical impact of human immunodeficiency virus-associated sensory neuropathy in the era of combination antiretroviral therapy: the CHARTER Study. Arch Neurol (2010) 2.91

Impact of combination antiretroviral therapy on cerebrospinal fluid HIV RNA and neurocognitive performance. AIDS (2009) 2.88

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 27-2004. A 79-year-old woman with disturbances in gait, cognition, and autonomic function. N Engl J Med (2004) 2.67

Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis. Arch Neurol (2006) 2.62

A pilot study of normobaric oxygen therapy in acute ischemic stroke. Stroke (2005) 2.58

Structural and metabolic brain changes in the striatum associated with methamphetamine abuse. Addiction (2007) 2.49

Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence. Am J Psychiatry (2004) 2.42

Multi-contrast human neonatal brain atlas: application to normal neonate development analysis. Neuroimage (2011) 2.41

Neuroanatomical assessment of biological maturity. Curr Biol (2012) 2.40

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 16-2003. A 58-year-old woman with left-sided weakness and a right frontal brain mass. N Engl J Med (2003) 2.39

Severity of leukoaraiosis and susceptibility to infarct growth in acute stroke. Stroke (2008) 2.34

Pancreaticoduodenectomy: a 20-year experience in 516 patients. Arch Surg (2004) 2.29

Impact of efavirenz on neuropsychological performance and symptoms in HIV-infected individuals. Ann Intern Med (2005) 2.26

Influence of gender on loss to follow-up in a large HIV treatment programme in western Kenya. Bull World Health Organ (2010) 2.21

Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study. Blood (2014) 2.21

Glial tumor grading and outcome prediction using dynamic spin-echo MR susceptibility mapping compared with conventional contrast-enhanced MR: confounding effect of elevated rCBV of oligodendrogliomas [corrected]. AJNR Am J Neuroradiol (2004) 2.21

Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21

Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke (2009) 2.20

The OpenMRS Implementers Network. Int J Med Inform (2009) 2.19

A concentration-independent method to measure exchange rates in PARACEST agents. Magn Reson Med (2010) 2.17

Safety of discontinuation of maintenance therapy for disseminated histoplasmosis after immunologic response to antiretroviral therapy. Clin Infect Dis (2004) 2.17

Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America. PLoS Med (2011) 2.17

Failure to initiate antiretroviral therapy, loss to follow-up and mortality among HIV-infected patients during the pre-ART period in Uganda. J Acquir Immune Defic Syndr (2013) 2.15

The effects of tamoxifen and estrogen on brain metabolism in elderly women. J Natl Cancer Inst (2002) 2.14

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10

Intraductal papillary mucinous neoplasms: predictors of malignant and invasive pathology. Ann Surg (2007) 2.10

Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study. AIDS (2007) 2.09

A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. Neuroimage (2004) 2.05

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. AIDS (2011) 2.04

Perfusion MRI and computerized cognitive test abnormalities in abstinent methamphetamine users. Psychiatry Res (2002) 2.02

Case records of the Massachusetts General Hospital. Case 11-2008. A 45-year-old man with changes in mental status after liver transplantation. N Engl J Med (2008) 2.02

Case records of the Massachusetts General Hospital. Case 18-2012. A 35-year-old man with neck pain, hoarseness, and dysphagia. N Engl J Med (2012) 2.02

Deformation-based morphometry of brain changes in alcohol dependence and abstinence. Neuroimage (2006) 2.01

Characterization and functionality of cardiac progenitor cells in congenital heart patients. Circulation (2011) 1.99

A systematic review to assess comparative effectiveness studies in epidural steroid injections for lumbar spinal stenosis and to estimate reimbursement amounts. PM R (2013) 1.99

Short-term improvements in disability mediate patient satisfaction after epidural corticosteroid injections for symptomatic lumbar spinal stenosis. Spine (Phila Pa 1976) (2015) 1.97

Common deactivation patterns during working memory and visual attention tasks: an intra-subject fMRI study at 4 Tesla. Hum Brain Mapp (2006) 1.96

Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era. J Neurovirol (2010) 1.95

An evaluation of neurocognitive status and markers of immune activation as predictors of time to death in advanced HIV infection. Arch Neurol (2007) 1.94

HIV-associated distal sensory polyneuropathy in the era of highly active antiretroviral therapy: the Manhattan HIV Brain Bank. Arch Neurol (2004) 1.91

Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circ Res (2006) 1.90

Inactivation of polycomb repressive complex 2 components in myeloproliferative and myelodysplastic/myeloproliferative neoplasms. Blood (2011) 1.90

Revision surgery following operations for lumbar stenosis. J Bone Joint Surg Am (2011) 1.90

The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke (2009) 1.89

Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol (2008) 1.88

Outcomes of HIV-infected orphaned and non-orphaned children on antiretroviral therapy in western Kenya. J Acquir Immune Defic Syndr (2006) 1.87

HIV-associated neurocognitive disorder: pathogenesis and therapeutic opportunities. J Neuroimmune Pharmacol (2010) 1.87

Outcomes of HIV-exposed children in western Kenya: efficacy of prevention of mother to child transmission in a resource-constrained setting. J Acquir Immune Defic Syndr (2010) 1.86

Additive effects of HIV and chronic methamphetamine use on brain metabolite abnormalities. Am J Psychiatry (2005) 1.86

CT and conventional and diffusion-weighted MR imaging in acute stroke: study in 691 patients at presentation to the emergency department. Radiology (2002) 1.85

Relationships among brain metabolites, cognitive function, and viral loads in antiretroviral-naïve HIV patients. Neuroimage (2002) 1.83

The risk of bankruptcy before and after brain or spinal cord injury: a glimpse of the iceberg's tip. Med Care (2007) 1.82

Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy. Arch Neurol (2004) 1.79

JC virus granule cell neuronopathy: A novel clinical syndrome distinct from progressive multifocal leukoencephalopathy. Ann Neurol (2005) 1.79

Smaller subcortical volumes and cognitive deficits in children with prenatal methamphetamine exposure. Psychiatry Res (2004) 1.78

Change in blood-brain barrier permeability during pediatric diabetic ketoacidosis treatment. Pediatr Crit Care Med (2010) 1.76

Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in Africa. Trop Med Int Health (2010) 1.75

Radiation necrosis versus glioma recurrence: conventional MR imaging clues to diagnosis. AJNR Am J Neuroradiol (2005) 1.75

Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change. J Clin Exp Neuropsychol (2011) 1.73

Enlarged striatum in abstinent methamphetamine abusers: a possible compensatory response. Biol Psychiatry (2005) 1.73

Adaptation of the attention network in human immunodeficiency virus brain injury. Ann Neurol (2004) 1.71