Published in Nat Immunol on June 01, 2003
Structure and signalling in the IL-17 receptor family. Nat Rev Immunol (2009) 6.38
New insights into the regulation of T cells by gamma(c) family cytokines. Nat Rev Immunol (2009) 5.57
Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitis. Inflamm Bowel Dis (2009) 3.32
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
Appendicitis, mesenteric lymphadenitis, and subsequent risk of ulcerative colitis: cohort studies in Sweden and Denmark. BMJ (2009) 2.22
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17. J Dent Res (2008) 2.05
Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression. Proc Natl Acad Sci U S A (2007) 1.85
Helper T cell diversity and plasticity. Curr Opin Immunol (2012) 1.63
Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis. Prog Neurobiol (2010) 1.54
The protective role of antibody responses during Mycobacterium tuberculosis infection. Clin Exp Immunol (2009) 1.48
Cytokine gene expression in peripheral blood mononuclear cells and tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis: evidence for an inherent proinflammatory gene expression pattern. Infect Immun (2004) 1.45
Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA. Proc Natl Acad Sci U S A (2008) 1.43
Danger signalling during cancer cell death: origins, plasticity and regulation. Cell Death Differ (2013) 1.39
Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells. Adv Drug Deliv Rev (2012) 1.25
T-bet is essential for the progression of experimental autoimmune encephalomyelitis. Immunology (2006) 1.25
Th1 type lymphocyte reactivity to metals in patients with total hip arthroplasty. J Orthop Surg Res (2008) 1.23
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease. J Allergy Clin Immunol (2013) 1.19
Cellular and humoral mechanisms involved in the control of tuberculosis. Clin Dev Immunol (2012) 1.16
An alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells. PLoS Med (2006) 1.15
T-helper-2 cytokine responses to Sj97 predict resistance to reinfection with Schistosoma japonicum. Infect Immun (2006) 1.15
A sopB deletion mutation enhances the immunogenicity and protective efficacy of a heterologous antigen delivered by live attenuated Salmonella enterica vaccines. Infect Immun (2008) 1.12
Differential immune and genetic responses in rat models of Crohn's colitis and ulcerative colitis. Am J Physiol Gastrointest Liver Physiol (2010) 1.08
IL-17 signaling in host defense against Candida albicans. Immunol Res (2011) 1.06
Regulation of autoimmune inflammation by pro-inflammatory cytokines. Immunol Lett (2008) 1.04
Is interferon-gamma the right marker for bacille Calmette-Guérin-induced immune protection? The missing link in our understanding of tuberculosis immunology. Clin Exp Immunol (2012) 1.03
Disturbance of cytokine networks in Sjögren's syndrome. Arthritis Res Ther (2011) 1.02
Th1/Th2 cytokine ratio in tissue transudates from patients with oral lichen planus. Mediators Inflamm (2007) 1.02
Salmonella vaccine vectors displaying delayed antigen synthesis in vivo to enhance immunogenicity. Infect Immun (2010) 1.02
Regulation of autoimmune arthritis by the pro-inflammatory cytokine interferon-gamma. Clin Immunol (2008) 1.02
The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PLoS One (2009) 1.01
Yersinia pestis with regulated delayed attenuation as a vaccine candidate to induce protective immunity against plague. Infect Immun (2010) 0.98
Allergic conjunctivitis exacerbates corneal allograft rejection by activating Th1 and th2 alloimmune responses. J Immunol (2010) 0.97
Immune surveillance of the central nervous system in multiple sclerosis--relevance for therapy and experimental models. J Neuroimmunol (2014) 0.93
Relapsing and progressive forms of multiple sclerosis: insights from pathology. Curr Opin Neurol (2014) 0.92
Expression of cytokine mRNA and protein in joints and lymphoid organs during the course of rat antigen-induced arthritis. Arthritis Res Ther (2005) 0.91
Effects of a Th1- versus a Th2-biased immune response in protection against Helicobacter pylori challenge in mice. Microb Pathog (2007) 0.90
IFN-gamma and IL-4 in saliva of patients with oral lichen planus: a study in an ethnic Chinese population. Inflammation (2009) 0.89
Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. J Child Adolesc Psychopharmacol (2009) 0.87
Enhanced expression of interferon-inducible protein 10 associated with Th1 profiles of chemokine receptor in autoimmune pulmonary inflammation of MRL/lpr mice. Arthritis Res Ther (2003) 0.87
Regulation of autoimmune arthritis by self-heat-shock proteins. Trends Immunol (2008) 0.85
Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells. Immunology (2006) 0.84
New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression. Ann N Y Acad Sci (2010) 0.84
A human-mouse chimeric model of obliterative bronchiolitis after lung transplantation. Am J Pathol (2011) 0.84
Immunological dysfunction, vaccination and Gulf War illness. Philos Trans R Soc Lond B Biol Sci (2006) 0.83
T Regulatory and T Helper 17 Cells in Primary Sjögren's Syndrome: Facts and Perspectives. Mediators Inflamm (2015) 0.82
Characterization of Th1- and Th2-type immune response in human multidrug-resistant tuberculosis. Eur J Clin Microbiol Infect Dis (2011) 0.82
Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8-42.2 degrees C. Eur J Appl Physiol (2005) 0.81
PPARγ Agonists in Adaptive Immunity: What Do Immune Disorders and Their Models Have to Tell Us? PPAR Res (2013) 0.80
Evaluation of YadC protein delivered by live attenuated Salmonella as a vaccine against plague. Pathog Dis (2013) 0.80
IL-17 regulates the expressions of RANKL and OPG in human periodontal ligament cells via TRAF6/TBK1-JNK/NF-κB pathways. Immunology (2014) 0.80
A colanic acid operon deletion mutation enhances induction of early antibody responses by live attenuated Salmonella vaccine strains. Infect Immun (2013) 0.79
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells. PLoS One (2012) 0.78
In search of the CTD. Nat Immunol (2003) 0.78
Self heat-shock protein 65-mediated regulation of autoimmune arthritis. J Autoimmun (2009) 0.78
Long-Term Stable Mixed Chimerism after Hematopoietic Stem Cell Transplantation in Patients with Non-Malignant Disease, Shall We Be Tolerant? PLoS One (2016) 0.78
Association between CTLA-4 gene promoter (49 A/G) in exon 1 polymorphisms and inflammatory bowel disease in the Tunisian population. Saudi J Gastroenterol (2009) 0.77
Bioluminescence imaging for IL-1β expression in experimental colitis. J Inflamm (Lond) (2013) 0.77
Childhood chronic anterior uveitis associated with vernal keratoconjunctivitis (VKC): successful treatment with topical tacrolimus. Case series. Pediatr Rheumatol Online J (2011) 0.76
T Helper 17 Cells in Primary Sjögren's Syndrome. J Clin Med (2017) 0.76
Systems Analysis of Early Host Gene Expression Provides Clues for Transient Mycobacterium avium ssp avium vs. Persistent Mycobacterium avium ssp paratuberculosis Intestinal Infections. PLoS One (2016) 0.75
Effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Immune Functions in Healthy Adults in a Randomized Controlled Trial. Immune Netw (2015) 0.75
Mechanisms of Cholera Toxin in the Modulation of TH17 Responses. Crit Rev Immunol (2015) 0.75
A Study of Association Between Oral Lichen Planus and Immune Balance of Th1/Th2 Cells. Inflammation (2015) 0.75
Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. J Am Soc Nephrol (2005) 3.57
Autoimmune hypophysitis. Endocr Rev (2005) 2.86
Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium. Circulation (2006) 2.58
Viruses as adjuvants for autoimmunity: evidence from Coxsackievirus-induced myocarditis. Rev Med Virol (2004) 2.35
Epidemiology of autoimmune diseases in Denmark. J Autoimmun (2007) 2.05
Sex differences in autoimmune disease from a pathological perspective. Am J Pathol (2008) 1.94
Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy. Circ Res (2010) 1.71
Pathogenesis of myocarditis and dilated cardiomyopathy. Adv Immunol (2008) 1.67
PrP conformational transitions alter species preference of a PrP-specific antibody. J Biol Chem (2010) 1.62
Cutting edge: cross-regulation by TLR4 and T cell Ig mucin-3 determines sex differences in inflammatory heart disease. J Immunol (2007) 1.61
Coxsackievirus-induced myocarditis in mice: a model of autoimmune disease for studying immunotoxicity. Methods (2007) 1.53
Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. J Immunol (2006) 1.48
Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation. Am J Pathol (2008) 1.41
IL-12 receptor beta 1 and Toll-like receptor 4 increase IL-1 beta- and IL-18-associated myocarditis and coxsackievirus replication. J Immunol (2003) 1.39
Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. Am J Transplant (2002) 1.38
Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon populations in Brazil: a cross-sectional study. Environ Health (2004) 1.38
Quantitative analysis of myocardial inflammation by flow cytometry in murine autoimmune myocarditis: correlation with cardiac function. Am J Pathol (2004) 1.38
Gonadectomy of male BALB/c mice increases Tim-3(+) alternatively activated M2 macrophages, Tim-3(+) T cells, Th2 cells and Treg in the heart during acute coxsackievirus-induced myocarditis. Brain Behav Immun (2008) 1.27
Autoimmune thyroid diseases. Curr Opin Rheumatol (2007) 1.27
Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy. Circulation (2005) 1.27
IL-12 protects against coxsackievirus B3-induced myocarditis by increasing IFN-gamma and macrophage and neutrophil populations in the heart. J Immunol (2005) 1.27
Relationship between surface accessibility for PpmA, PsaA, and PspA and antibody-mediated immunity to systemic infection by Streptococcus pneumoniae. Infect Immun (2005) 1.22
Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. J Am Soc Nephrol (2004) 1.22
Autoimmune hypophysitis of SJL mice: clinical insights from a new animal model. Endocrinology (2008) 1.20
Autoimmune myocarditis: cellular mediators of cardiac dysfunction. Autoimmun Rev (2004) 1.19
Cell damage and autoimmunity: a critical appraisal. J Autoimmun (2008) 1.19
Proinflammatory cytokines in heart failure: double-edged swords. Heart Fail Rev (2010) 1.18
Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease. Environ Health Perspect (2008) 1.17
Mechanisms of environmental influence on human autoimmunity: a National Institute of Environmental Health Sciences expert panel workshop. J Autoimmun (2012) 1.16
Women and autoimmune diseases. Emerg Infect Dis (2004) 1.15
Significant variation in serotype-specific immunogenicity of the seven-valent Streptococcus pneumoniae capsular polysaccharide-CRM197 conjugate vaccine occurs despite vigorous T cell help induced by the carrier protein. J Infect Dis (2003) 1.14
Sex differences in coxsackievirus B3-induced myocarditis: IL-12Rbeta1 signaling and IFN-gamma increase inflammation in males independent from STAT4. Brain Res (2006) 1.14
Impaired up-regulation of CD25 on CD4+ T cells in IFN-gamma knockout mice is associated with progression of myocarditis to heart failure. Proc Natl Acad Sci U S A (2004) 1.12
Animal models for autoimmune myocarditis and autoimmune thyroiditis. Methods Mol Med (2004) 1.11
Autoimmune thyroiditis and ROS. Autoimmun Rev (2008) 1.11
Pituitary autoimmunity: 30 years later. Autoimmun Rev (2008) 1.11
Genetic complexity of autoimmune myocarditis. Autoimmun Rev (2007) 1.10
Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14(+) monocytes in frail older adults. Mech Ageing Dev (2008) 1.08
Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis. Circulation (2008) 1.05
Mast cells and innate cytokines are associated with susceptibility to autoimmune heart disease following coxsackievirus B3 infection. Autoimmunity (2004) 1.04
Decreased expression of tumor necrosis factor family receptors involved in humoral immune responses in preterm neonates. Blood (2007) 1.03
IL-12 overexpression in mice as a model for Sjögren lung disease. Am J Physiol Lung Cell Mol Physiol (2006) 1.00
Macrophages participate in IL-17-mediated inflammation. Eur J Immunol (2012) 1.00
Type 1 diabetes: virus infection or autoimmune disease? Nat Immunol (2002) 1.00
Complement component C3d-antigen complexes can either augment or inhibit B lymphocyte activation and humoral immunity in mice depending on the degree of CD21/CD19 complex engagement. J Immunol (2005) 0.99
Immunoproteasome overexpression underlies the pathogenesis of thyroid oncocytes and primary hypothyroidism: studies in humans and mice. PLoS One (2009) 0.99
Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis. Clin Vaccine Immunol (2006) 0.99
A novel model of drug hapten-induced hepatitis with increased mast cells in the BALB/c mouse. Exp Mol Pathol (2005) 0.97
Increased thyroidal fat and goitrous hypothyroidism induced by interferon-gamma. Int J Exp Pathol (2005) 0.97
Novel model of constrictive pericarditis associated with autoimmune heart disease in interferon-gamma-knockout mice. Circulation (2004) 0.97
Significance of prediagnostic thyroid antibodies in women with autoimmune thyroid disease. J Clin Endocrinol Metab (2011) 0.96
Interleukin (IL)-12-driven primary hypothyroidism: the contrasting roles of two Th1 cytokines (IL-12 and interferon-gamma). Endocrinology (2005) 0.95
Criteria for environmentally associated autoimmune diseases. J Autoimmun (2012) 0.95
Cutting edge: a critical role for IL-10 in induction of nasal tolerance in experimental autoimmune myocarditis. J Immunol (2002) 0.95
The odd couple: a fresh look at autoimmunity and immunodeficiency. J Autoimmun (2010) 0.92
Influence of signal transducer and activator of transcription-1 signaling on thyroid morphology and function. Endocrinology (2009) 0.92
Expression of class II major histocompatibility complex molecules on thyrocytes does not cause spontaneous thyroiditis but mildly increases its severity after immunization. Endocrinology (2004) 0.91
Pregnancy, postpartum autoimmune thyroiditis, and autoimmune hypophysitis: intimate relationships. Autoimmun Rev (2009) 0.90
Desflurane hepatitis associated with hapten and autoantigen-specific IgG4 antibodies. Anesth Analg (2007) 0.89
The pathogenic role of anti-thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice. Hum Reprod (2003) 0.89
Fatal eosinophilic myocarditis develops in the absence of IFN-γ and IL-17A. J Immunol (2013) 0.88
Cardiac troponins and autoimmunity: their role in the pathogenesis of myocarditis and of heart failure. Clin Immunol (2009) 0.88
Studies on murine thyroiditis: new insights from organ flow cytometry. Thyroid (2003) 0.88
The prevalence of 30 ICD-10 autoimmune diseases in Denmark. Immunol Res (2010) 0.88
Macrophage diversity in cardiac inflammation: a review. Immunobiology (2011) 0.87
Infection and thyroid autoimmunity: A seroepidemiologic study of TPOaAb. Autoimmunity (2009) 0.87
Pituitary antibodies in women with Hashimoto's thyroiditis: prevalence in diagnostic and prediagnostic sera. Thyroid (2012) 0.87
Sex bias in experimental immune-mediated, drug-induced liver injury in BALB/c mice: suggested roles for Tregs, estrogen, and IL-6. PLoS One (2013) 0.86
Mechanisms of IFNγ regulation of autoimmune myocarditis. Exp Mol Pathol (2010) 0.86
Iodine and IFN-gamma synergistically enhance intercellular adhesion molecule 1 expression on NOD.H2h4 mouse thyrocytes. J Immunol (2005) 0.86
Two autoimmune diabetes loci influencing T cell apoptosis control susceptibility to experimental autoimmune myocarditis. J Immunol (2005) 0.86
Thyroid-specific expression of IFN-gamma limits experimental autoimmune thyroiditis by suppressing lymphocyte activation in cervical lymph nodes. J Immunol (2003) 0.86
Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24. Endocrinology (2008) 0.85
Genetic fusion of three tandem copies of murine C3d sequences to diphtheria toxin fragment B elicits a decreased fragment B-specific antibody response. Immunol Lett (2005) 0.85
Low-dose inorganic mercury increases severity and frequency of chronic coxsackievirus-induced autoimmune myocarditis in mice. Toxicol Sci (2011) 0.84
Kinetics of mononuclear cell infiltration and cytokine expression in iodine-induced thyroiditis in the NOD-H2h4 mouse. Exp Mol Pathol (2003) 0.84
Suppressive and pro-inflammatory roles for IL-4 in the pathogenesis of experimental drug-induced liver injury. Eur J Immunol (2009) 0.83
L.E.A.P.S. heteroconjugate is able to prevent and treat experimental autoimmune myocarditis by altering trafficking of autoaggressive cells to the heart. Int Immunopharmacol (2008) 0.83
Enhanced immunogenicity of pneumococcal surface adhesin A by genetic fusion to cytokines and evaluation of protective immunity in mice. Infect Immun (2002) 0.82
IP-10 protects while MIP-2 promotes experimental anesthetic hapten - induced hepatitis. J Autoimmun (2009) 0.82
Adhesion molecules as susceptibility factors in spontaneous autoimmune thyroiditis in the NOD-H2h4 mouse. Exp Mol Pathol (2002) 0.82
Sex differences in a murine model of Sjögren's syndrome. Ann N Y Acad Sci (2009) 0.82
Early chemokine expression induced by interferon-gamma in a murine model of Hashimoto's thyroiditis. Exp Mol Pathol (2004) 0.82
Enhanced immunogenicity of pneumococcal surface adhesin A (PsaA) in mice via fusion to recombinant human B lymphocyte stimulator (BLyS). Biol Direct (2011) 0.82
On the implications of polyclonal B cell activation. Nat Immunol (2003) 0.81
Genetic differences in bone marrow-derived lymphoid lineages control susceptibility to experimental autoimmune myocarditis. J Immunol (2008) 0.80
Maternal thyroid autoantibodies during the third trimester and hearing deficits in children: an epidemiologic assessment. Am J Epidemiol (2007) 0.79
A locus on chromosome 1 promotes susceptibility of experimental autoimmune myocarditis and lymphocyte cell death. Clin Immunol (2008) 0.79
Toll-like receptor-MyD88 and Fc receptor pathways of mast cells mediate the thyroid dysfunctions observed during nonthyroidal illness. Proc Natl Acad Sci U S A (2007) 0.79
Thyroid autoantibodies are associated with a reduced prevalence of frailty in community-dwelling older women. J Clin Endocrinol Metab (2010) 0.79
Autoantibody heritability in thyroiditis: IgG subclass contributions. Autoimmunity (2010) 0.78
Trifluoroacetylated IgG4 antibodies in a child with idiosyncratic acute liver failure after first exposure to halothane. J Pediatr Gastroenterol Nutr (2008) 0.78
Complement receptors regulate lipopolysaccharide-induced T-cell stimulation. Immunology (2005) 0.78
NKT cell regulation of autoimmune thyroiditis. Autoimmunity (2003) 0.77
Cardiomyopathy is linked to complement activation. Am J Pathol (2002) 0.77
Infection and autoimmunity: theme and variations. Curr Opin Rheumatol (2012) 0.76
Reproducibility of immunological tests used to assess multiple chemical sensitivity syndrome. Clin Diagn Lab Immunol (2003) 0.76