Toshio Hakoshima

Author PubWeight™ 47.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. Nature 2008 3.29
2 Structural basis for recruitment of human flap endonuclease 1 to PCNA. EMBO J 2004 2.57
3 Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J 2003 1.70
4 Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule. Proc Natl Acad Sci U S A 2010 1.49
5 Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN. Structure 2010 1.46
6 Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. Proc Natl Acad Sci U S A 2007 1.41
7 Structural basis for NHERF recognition by ERM proteins. Structure 2006 1.41
8 Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil. Structure 2006 1.37
9 Structures of D14 and D14L in the strigolactone and karrikin signaling pathways. Genes Cells 2013 1.30
10 Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J Biol Chem 2001 1.30
11 Structural basis for CD44 recognition by ERM proteins. J Biol Chem 2008 1.26
12 Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein. J Biol Chem 2004 1.11
13 Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain. EMBO J 2011 1.08
14 Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex. J Biol Chem 2007 1.05
15 Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. J Biol Chem 2003 1.04
16 Structural basis of PSGL-1 binding to ERM proteins. Genes Cells 2007 1.04
17 Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins. J Mol Biol 2008 1.01
18 Crystal structure of the HRDC domain of human Werner syndrome protein, WRN. J Biol Chem 2006 1.00
19 Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632. J Biochem 2006 0.98
20 Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP. Proc Natl Acad Sci U S A 2002 0.98
21 A diphtheria toxin receptor deficient in epidermal growth factor-like biological activity. J Biochem 2006 0.97
22 The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module. EMBO J 2009 0.95
23 Crystal structure of human Rad GTPase of the RGK-family. Genes Cells 2006 0.89
24 Preparation and crystallization of human flap endonuclease FEN-1 in complex with proliferating-cell nuclear antigen, PCNA. Acta Crystallogr D Biol Crystallogr 2003 0.89
25 Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay. Genes Cells 2005 0.87
26 Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism. Proc Natl Acad Sci U S A 2013 0.85
27 Solution structure of the HRDC domain of human Bloom syndrome protein BLM. J Biochem 2010 0.83
28 Crystallographic characterization of the radixin FERM domain bound to the C-terminal region of the human Na+/H+-exchanger regulatory factor (NHERF). Acta Crystallogr D Biol Crystallogr 2002 0.83
29 Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus. Proteins 2005 0.83
30 Structure of the RecQ C-terminal domain of human Bloom syndrome protein. Sci Rep 2013 0.81
31 The crystal structure of N(1)-[2-(2-amino-ethylamino)-ethyl]-ethane-1,2-diamine (polyamines) binding to the minor groove of d(CGCGCG)(2), hexamer at room temperature. FEBS Lett 2002 0.81
32 Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tails of adhesion molecules CD43 and PSGL-1. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.78
33 Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304. Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 0.78
34 Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells 2014 0.78
35 Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR. Biochim Biophys Acta 2012 0.77
36 Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8 and PYR1/RCAR11 in the presence of (+)-abscisic acid. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.77
37 Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.77
38 Preparation and preliminary X-ray diffraction analysis of crystals of bacterial flagellar sigma factor sigma 28 in complex with the sigma 28-binding region of its antisigma factor, FlgM. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.77
39 Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of membrane-type 1 matrix metalloproteinase (MT1-MMP). Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.76
40 Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: use of a DPCS kit for efficient protein-DNA complex crystallization. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.76
41 Role of loop structures of neuropsin in the activity of serine protease and regulated secretion. J Biol Chem 2002 0.76
42 Mechanism of high-affinity abscisic acid binding to PYL9/RCAR1. Genes Cells 2014 0.76
43 Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tail of adhesion molecule CD44. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.76
44 A molecular mechanism of P-loop pliability of Rho-kinase investigated by molecular dynamic simulation. J Comput Aided Mol Des 2008 0.75
45 Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.75
46 Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.75
47 [Structural studies of the plant hormone receptors]. Tanpakushitsu Kakusan Koso 2009 0.75
48 [Recent progress in structural studies of +TIPs]. Tanpakushitsu Kakusan Koso 2008 0.75