Published in Acta Crystallogr D Biol Crystallogr on April 25, 2003
Structural basis for recruitment of human flap endonuclease 1 to PCNA. EMBO J (2004) 2.57
Interaction of estrogen receptor alpha with proliferating cell nuclear antigen. Nucleic Acids Res (2007) 1.01
Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha. BMC Mol Biol (2008) 0.89
Crystallographic study of G178S mutant of human proliferating cell nuclear antigen. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.84
Crystallization and preliminary crystallographic analysis of the catalytic domain of human flap endonuclease 1 in complex with a nicked DNA product: use of a DPCS kit for efficient protein-DNA complex crystallization. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.76
Destabilization of the PCNA trimer mediated by its interaction with the NEIL1 DNA glycosylase. Nucleic Acids Res (2017) 0.75
Gibberellin-induced DELLA recognition by the gibberellin receptor GID1. Nature (2008) 3.29
De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy. Nat Genet (2008) 2.98
Structural basis for recruitment of human flap endonuclease 1 to PCNA. EMBO J (2004) 2.57
Crystal structure of the DsbB-DsbA complex reveals a mechanism of disulfide bond generation. Cell (2006) 2.20
Structural basis of the substrate-specific two-step catalysis of long chain fatty acyl-CoA synthetase dimer. J Biol Chem (2004) 1.89
DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J Biol Chem (2001) 1.75
Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex. EMBO J (2003) 1.70
Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule. Proc Natl Acad Sci U S A (2010) 1.49
Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN. Structure (2010) 1.46
Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition. Proc Natl Acad Sci U S A (2007) 1.41
Structural basis for NHERF recognition by ERM proteins. Structure (2006) 1.41
Interaction of the Vp3 nuclear localization signal with the importin alpha 2/beta heterodimer directs nuclear entry of infecting simian virus 40. J Virol (2002) 1.40
Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil. Structure (2006) 1.37
Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay. Am J Hum Genet (2010) 1.35
Structures of D14 and D14L in the strigolactone and karrikin signaling pathways. Genes Cells (2013) 1.30
Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain. J Biol Chem (2001) 1.30
Structural basis for CD44 recognition by ERM proteins. J Biol Chem (2008) 1.26
Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy. Am J Hum Genet (2011) 1.24
Sonoporation by single-shot pulsed ultrasound with microbubbles adjacent to cells. Biophys J (2009) 1.23
Missense mutations in the DNA-binding/dimerization domain of NFIX cause Sotos-like features. J Hum Genet (2012) 1.16
Spontaneous pneumomediastinum: an algorithm for diagnosis and management. Ther Adv Respir Dis (2009) 1.14
Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein. J Biol Chem (2004) 1.11
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domain. EMBO J (2011) 1.08
Structural basis for type II membrane protein binding by ERM proteins revealed by the radixin-neutral endopeptidase 24.11 (NEP) complex. J Biol Chem (2007) 1.05
Structural basis of PSGL-1 binding to ERM proteins. Genes Cells (2007) 1.04
Parallel coiled-coil association of the RhoA-binding domain in Rho-kinase. J Biol Chem (2003) 1.04
PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA. Genes Cells (2002) 1.04
Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins. J Mol Biol (2008) 1.01
Crystal structure of the HRDC domain of human Werner syndrome protein, WRN. J Biol Chem (2006) 1.00
Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP. Proc Natl Acad Sci U S A (2002) 0.98
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632. J Biochem (2006) 0.98
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site. Biochemistry (2010) 0.97
A diphtheria toxin receptor deficient in epidermal growth factor-like biological activity. J Biochem (2006) 0.97
The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module. EMBO J (2009) 0.95
Genetic basis of patients with bacille Calmette-Guérin osteomyelitis in Japan: identification of dominant partial interferon-gamma receptor 1 deficiency as a predominant type. J Infect Dis (2002) 0.93
Prospective evaluation of the relationship between acute exacerbations of COPD and gastroesophageal reflux disease diagnosed by questionnaire. Respir Med (2011) 0.90
Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography. Biochem J (2004) 0.90
Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg Med Chem Lett (2012) 0.90
Crystal structure of human Rad GTPase of the RGK-family. Genes Cells (2006) 0.89
The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b. Biochem Biophys Res Commun (2009) 0.89
Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. Bioorg Med Chem (2010) 0.89
Pyrimidine dimer formation and oxidative damage in M13 bacteriophage inactivation by ultraviolet C irradiation. Photochem Photobiol (2003) 0.88
Discovery of natural products possessing selective eukaryotic readthrough activity: 3-epi-deoxynegamycin and its leucine adduct. ChemMedChem (2014) 0.88
Syndecan binding sites in the laminin alpha1 chain G domain. Biochemistry (2003) 0.87
Crystal structure of the protein histidine phosphatase SixA in the multistep His-Asp phosphorelay. Genes Cells (2005) 0.87
Blockade of autoantibody-initiated tissue damage by using recombinant fab antibody fragments against pathogenic autoantigen. Am J Pathol (2009) 0.85
Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism. Proc Natl Acad Sci U S A (2013) 0.85
N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases. Bioorg Med Chem (2010) 0.85
Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen. Biochem Biophys Res Commun (2004) 0.85
Nitric oxide mediates selective degeneration of hypothalamic orexin neurons through dysfunction of protein disulfide isomerase. J Neurosci (2013) 0.84
Crystal structure of decameric peroxiredoxin (AhpC) from Amphibacillus xylanus. Proteins (2005) 0.83
Solution structure of the HRDC domain of human Bloom syndrome protein BLM. J Biochem (2010) 0.83
Crystallographic characterization of the radixin FERM domain bound to the C-terminal region of the human Na+/H+-exchanger regulatory factor (NHERF). Acta Crystallogr D Biol Crystallogr (2002) 0.83
Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding. Biochemistry (2010) 0.82
The native cyclobutane pyrimidine dimer photolyase of rice is phosphorylated. Plant Physiol (2008) 0.82
Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay. Mol Membr Biol (2014) 0.82
Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model. J Immunol (2010) 0.81
Discovery of N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (TAK-593), a highly potent VEGFR2 kinase inhibitor. Bioorg Med Chem (2013) 0.81
Structure of the RecQ C-terminal domain of human Bloom syndrome protein. Sci Rep (2013) 0.81
The crystal structure of N(1)-[2-(2-amino-ethylamino)-ethyl]-ethane-1,2-diamine (polyamines) binding to the minor groove of d(CGCGCG)(2), hexamer at room temperature. FEBS Lett (2002) 0.81
Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment. Biochim Biophys Acta (2013) 0.81
Estimation of 24-hour urine protein quantity by the morning-urine protein/creatinine ratio. Clin Exp Nephrol (2007) 0.81
An increase in apoptosis and reduction in αB-crystallin expression levels in the lens underlie the cataractogenesis of Morioka cataract (MCT) mice. Med Mol Morphol (2011) 0.80
Biological characteristics of two lysines on human serum albumin in the high-affinity binding of 4Z,15Z-bilirubin-IXα revealed by phage display. FEBS J (2011) 0.80
Biochemical and biological properties of DNA photolyases derived from utraviolet-sensitive rice cultivars. Genes Genet Syst (2007) 0.79
Copper-catalyzed borylation reactions of alkynes and arynes. Angew Chem Int Ed Engl (2011) 0.79
Suppression of Aggrus/podoplanin-induced platelet aggregation and pulmonary metastasis by a single-chain antibody variable region fragment. Cancer Med (2014) 0.79
Disseminated Mycobacterium abscessus Infection Following Septic Arthritis: A Case Report and Review of the Literature. Medicine (Baltimore) (2015) 0.78
Crystallographic characterization of the radixin FERM domain bound to the cytoplasmic tails of adhesion molecules CD43 and PSGL-1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78
Expression of transforming growth factor β and fibroblast growth factor 2 in the lens epithelium of Morioka cataract mice. Congenit Anom (Kyoto) (2014) 0.78
Rational approach to the synthesis, evaluation, and (68)ga labeling of a novel 4-anilinoquinoline epidermal growth factor receptor inhibitor as a new imaging agent that selectively targets the epidermal growth factor receptor tyrosine kinase. Cancer Biother Radiopharm (2010) 0.78
Manadosterols A and B, sulfonated sterol dimers inhibiting the Ubc13-Uev1A interaction, isolated from the marine sponge Lissodendryx fibrosa. J Nat Prod (2012) 0.78
Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.78
[Relationship between chronic obstructive pulmonary disease and gastroesophageal reflux disease defined by the Frequency Scale for the Symptoms of gastroesophageal reflux disease]. Nihon Kokyuki Gakkai Zasshi (2010) 0.78
Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells (2014) 0.78
Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors. Bioorg Med Chem (2013) 0.78
Spatial orientation of mitochondrial processing peptidase and a preprotein revealed by fluorescence resonance energy transfer. J Biochem (2007) 0.78
Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR. Biochim Biophys Acta (2012) 0.77
Crystallographic characterization of the membrane-targeting domains of the Rac-specific guanine nucleotide-exchange factors Tiam1 and Tiam2. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.77
Novel cataract mouse model using ddY strain: hereditary and histological characteristics. J Vet Med Sci (2009) 0.77
Crystallization of the plant hormone receptors PYL9/RCAR1, PYL5/RCAR8 and PYR1/RCAR11 in the presence of (+)-abscisic acid. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77