Published in Circulation on June 02, 2003
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet (2004) 2.66
Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation. Heart Rhythm (2007) 2.62
Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation. Circulation (2008) 2.56
Familial aggregation in lone atrial fibrillation. Hum Genet (2005) 2.55
A common polymorphism in SCN5A is associated with lone atrial fibrillation. Clin Pharmacol Ther (2007) 2.17
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. J Interv Card Electrophysiol (2012) 2.08
Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J (2009) 2.06
Mutation in the S3 segment of KCNQ1 results in familial lone atrial fibrillation. Heart Rhythm (2009) 1.87
Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation. J Am Coll Cardiol (2008) 1.77
Ablation of a Ca2+-activated K+ channel (SK2 channel) results in action potential prolongation in atrial myocytes and atrial fibrillation. J Physiol (2009) 1.74
Mutations in the long QT gene, KCNQ1, are an uncommon cause of atrial fibrillation. Heart (2004) 1.45
Familial aggregation of atrial fibrillation: a study in Danish twins. Circ Arrhythm Electrophysiol (2009) 1.32
Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation. Heart Rhythm (2008) 1.27
Critical roles of a small conductance Ca²⁺-activated K⁺ channel (SK3) in the repolarization process of atrial myocytes. Cardiovasc Res (2013) 1.23
Genome-wide linkage scan identifies a novel genetic locus on chromosome 5p13 for neonatal atrial fibrillation associated with sudden death and variable cardiomyopathy. Circulation (2004) 1.21
Potassium channel gene mutations rarely cause atrial fibrillation. BMC Med Genet (2006) 1.21
Genetics of atrial fibrillation. Heart Fail Clin (2010) 1.15
A first-degree family history in lone atrial fibrillation patients. Heart Rhythm (2008) 1.14
Genetic mechanisms of atrial fibrillation: impact on response to treatment. Nat Rev Cardiol (2013) 1.11
Atrial fibrillation in congestive heart failure. Heart Fail Clin (2010) 1.07
Genetics of atrial fibrillation: implications for future research directions and personalized medicine. Circ Arrhythm Electrophysiol (2010) 1.01
Long-term risk of atrial fibrillation with symptomatic gastroesophageal reflux disease and esophagitis. Am J Cardiol (2008) 0.97
Genetics of atrial fibrillation. Cardiol Clin (2009) 0.96
Genetics of atrial fibrillation: from families to genomes. J Hum Genet (2015) 0.96
Monogenic atrial fibrillation as pathophysiological paradigms. Cardiovasc Res (2010) 0.94
Interleukin-6 promoter polymorphisms and susceptibility to atrial fibrillation in elderly Han Chinese patients with essential hypertension. J Interferon Cytokine Res (2012) 0.92
The changing epidemiology and natural history of nonvalvular atrial fibrillation: clinical implications. Trans Am Clin Climatol Assoc (2004) 0.91
Genetics of atrial fibrillation. Med Clin North Am (2008) 0.88
The "missing" link in atrial fibrillation heritability. J Electrocardiol (2011) 0.87
Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation. Heart Rhythm (2013) 0.84
Lone atrial fibrillation: influence of familial disease on gender predilection. J Cardiovasc Electrophysiol (2008) 0.84
Targeted deep sequencing reveals no definitive evidence for somatic mosaicism in atrial fibrillation. Circ Cardiovasc Genet (2014) 0.84
Outcomes Associated With Familial Versus Nonfamilial Atrial Fibrillation: A Matched Nationwide Cohort Study. J Am Heart Assoc (2016) 0.81
Lone AF - etiologic factors and genetic insights into pathophysiolgy. J Atr Fibrillation (2010) 0.80
[Genetics of atrial fibrillation: rare mutations, common variants and clinical relevance?]. Herzschrittmacherther Elektrophysiol (2006) 0.79
Molecular genetics of atrial fibrillation. Genome Med (2009) 0.79
Gastroesophageal reflux disease and atrial fibrillation: a nationwide population-based study. PLoS One (2012) 0.79
Genetics of atrial fibrillation and possible implications for ischemic stroke. Stroke Res Treat (2011) 0.77
Personalized medicine and atrial fibrillation: will it ever happen? BMC Med (2012) 0.76
Arrhythmia pharmacogenomics: methodological considerations. Curr Pharm Des (2009) 0.76
The Role of Pharmacogenetics in Atrial Fibrillation Therapeutics: Is Personalized Therapy in Sight? J Cardiovasc Pharmacol (2016) 0.76
Is Atrial Fibrillation a Risk Factor for Gastroesophageal Reflux Disease Occurrence? Medicine (Baltimore) (2015) 0.75
Atrial fibrillation in cardiac channelopathies. Indian Pacing Electrophysiol J (2009) 0.75
Recent breakthroughs in the genetics of atrial fibrillation. Neth Heart J (2003) 0.75
Cardiac sodium channel variants: action players with many faces. Heart Rhythm (2008) 0.75
Molecular genetic analysis of six Dutch families with atrial fibrillation. Neth Heart J (2005) 0.75
Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes. Circ Res (2017) 0.75
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature (2007) 8.03
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet (2004) 3.88
C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling. Cell (2010) 2.68
High-throughput assay for small molecules that modulate zebrafish embryonic heart rate. Nat Chem Biol (2005) 2.64
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol (2004) 2.57
Familial aggregation in lone atrial fibrillation. Hum Genet (2005) 2.55
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation (2003) 2.42
Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation (2006) 2.40
Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure. J Am Coll Cardiol (2006) 2.29
Klf2 is an essential regulator of vascular hemodynamic forces in vivo. Dev Cell (2006) 2.26
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Sustained improvement in left ventricular diastolic function after alcohol septal ablation for hypertrophic obstructive cardiomyopathy. Eur Heart J (2006) 2.14
Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J (2009) 2.06
Notch1b and neuregulin are required for specification of central cardiac conduction tissue. Development (2006) 2.00
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Nat Med (2012) 1.97
Pattern recognition: combining informatics and genetics to re-evaluate conduction disease. Heart (2012) 1.91
Persistent and reversible cardiac dysfunction among amateur marathon runners. Eur Heart J (2006) 1.88
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am J Hum Genet (2013) 1.87
Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy. Heart Rhythm (2011) 1.85
Echocardiographic evaluation in asymptomatic relatives of patients with dilated cardiomyopathy reveals preclinical disease. Ann Intern Med (2005) 1.85
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss. Nat Genet (2005) 1.80
In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. Am J Physiol Heart Circ Physiol (2006) 1.77
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy. Am J Hum Genet (2006) 1.68
C-Reactive protein in lone atrial fibrillation. Am J Cardiol (2006) 1.68
Cardiac sodium channel gene variants and sudden cardiac death in women. Circulation (2007) 1.67
The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials (2014) 1.62
Closer look at genetic testing in long-QT syndrome: will DNA diagnostics ever be enough? Circulation (2009) 1.56
ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural heart disease: implications for electrical remodeling. Heart Rhythm (2009) 1.55
Cardiac sodium channel mutation in atrial fibrillation. Heart Rhythm (2007) 1.50
Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report. Arch Neurol (2011) 1.49
Hemodynamic effects of inhaled nitric oxide in right ventricular myocardial infarction and cardiogenic shock. J Am Coll Cardiol (2004) 1.47
Images in cardiovascular medicine. Covered stent septal ablation for hypertrophic obstructive cardiomyopathy: initial success but ultimate failure resulting from collateral formation. Circulation (2003) 1.47
Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol Cell Biol (2004) 1.46
Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation (2009) 1.41
Compassionate use of the amplatzer ASD closure device for residual postinfarction ventricular septal rupture following surgical repair. Catheter Cardiovasc Interv (2003) 1.39
Human-zebrafish non-coding conserved elements act in vivo to regulate transcription. Nucleic Acids Res (2005) 1.39
Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse. Proc Natl Acad Sci U S A (2003) 1.33
Myocardial adaptation to short-term high-intensity exercise in highly trained athletes. J Am Soc Echocardiogr (2006) 1.23
Common variants in cardiac ion channel genes are associated with sudden cardiac death. Circ Arrhythm Electrophysiol (2010) 1.22
Potassium channel gene mutations rarely cause atrial fibrillation. BMC Med Genet (2006) 1.21
A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet (2014) 1.14
High-resolution cardiovascular function confirms functional orthology of myocardial contractility pathways in zebrafish. Physiol Genomics (2010) 1.10
Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration. Proc Natl Acad Sci U S A (2014) 1.10
Purification of hearts from zebrafish embryos. Biotechniques (2006) 1.07
Defining the pathogenicity of DNA sequence variation. Circ Cardiovasc Genet (2009) 1.07
Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish. Am J Physiol Heart Circ Physiol (2013) 1.06
Animal models for arrhythmias. Cardiovasc Res (2005) 1.05
Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish. Dis Model Mech (2011) 1.03
Carotid intima-media thickness is associated with premature parental coronary heart disease: the Framingham Heart Study. Circulation (2003) 1.02
In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res (2011) 1.01
Ion channel mutations in AF: signal or noise? Heart Rhythm (2008) 0.99
Aging syndrome genes and premature coronary artery disease. BMC Med Genet (2005) 0.95
Techniques for the in vivo assessment of cardio-renal function in zebrafish (Danio rerio) larvae. J Physiol (2012) 0.94
A novel locus for dilated cardiomyopathy, diffuse myocardial fibrosis, and sudden death on chromosome 10q25-26. J Am Coll Cardiol (2006) 0.92
A one-page summary report of genome sequencing for the healthy adult. Public Health Genomics (2015) 0.92
Hedgehog signaling via angiopoietin1 is required for developmental vascular stability. Mech Dev (2010) 0.91
Arrhythmogenic right ventricular cardiomyopathy. Heart Fail Clin (2010) 0.89
Genetics of atrial fibrillation. Med Clin North Am (2008) 0.88
Genetic testing in cardiovascular diseases. Curr Opin Cardiol (2014) 0.88
Next-generation genome-wide association studies: time to focus on phenotype? Circ Cardiovasc Genet (2011) 0.88
The genetics of atrial fibrillation. Curr Opin Cardiol (2010) 0.87
Adrenergic-receptor polymorphisms and heart failure. N Engl J Med (2002) 0.87
Myocardial blood flow and oxygen consumption in patients with Friedreich's ataxia prior to the onset of cardiomyopathy. Coron Artery Dis (2007) 0.86
Chemical and metabolomic screens identify novel biomarkers and antidotes for cyanide exposure. FASEB J (2013) 0.86
The zebrafish: scalable in vivo modeling for systems biology. Wiley Interdiscip Rev Syst Biol Med (2010) 0.85
Eya4 regulation of Na+/K+-ATPase is required for sensory system development in zebrafish. Development (2008) 0.85
Differential activation of natriuretic peptide receptors modulates cardiomyocyte proliferation during development. Development (2013) 0.84
Acquisition, Analysis, and Sharing of Data in 2015 and Beyond: A Survey of the Landscape: A Conference Report From the American Heart Association Data Summit 2015. J Am Heart Assoc (2015) 0.84
Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish. Development (2014) 0.84
Acute predictors of subacute complete heart block after alcohol septal ablation for obstructive hypertrophic cardiomyopathy. Am J Cardiol (2005) 0.83
STARS is essential to maintain cardiac development and function in vivo via a SRF pathway. PLoS One (2012) 0.83
Prioritizing causal disease genes using unbiased genomic features. Genome Biol (2014) 0.82
Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association. Circulation (2015) 0.81
Comparison of echocardiographic and cardiac magnetic resonance imaging in hypertrophic cardiomyopathy sarcomere mutation carriers without left ventricular hypertrophy. Circ Cardiovasc Genet (2013) 0.81
Action and the actionability in exome variation. Circ Cardiovasc Genet (2012) 0.79
Fatty acid ethyl esters: recent observations. Prostaglandins Leukot Essent Fatty Acids (2002) 0.78
Symptoms in atrial fibrillation: why keep score? Circ Arrhythm Electrophysiol (2009) 0.78
Cardiovascular regulation during body unweighting by lower body positive pressure. Aviat Space Environ Med (2013) 0.78
Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target. Curr Pharm Des (2007) 0.78
Clinical screening and genetic testing. Clin Lab Med (2010) 0.77
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. EMBO Mol Med (2015) 0.76
Sequential effects of spadetail, one-eyed pinhead and no tail on midline convergence of nephric primordia during zebrafish embryogenesis. Dev Biol (2013) 0.76
Genetic screening and risk assessment in hypertrophic cardiomyopathy. J Am Coll Cardiol (2004) 0.76
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. J Clin Invest (2017) 0.75
Risk stratification in the long-QT syndrome. N Engl J Med (2003) 0.75
Clinical screening and genetic testing. Heart Fail Clin (2010) 0.75
Management strategy in 249 consecutive patients with obstructive hypertrophic cardiomyopathy referred to a dedicated program. Am J Cardiol (2012) 0.75
A dream, a journey, and a promise: the inauguration of Circulation: Cardiovascular Genetics. Circ Cardiovasc Genet (2008) 0.75
Mitral valve ring dehiscence with an aorta-left atrial fistula. Eur J Echocardiogr (2006) 0.75