Published in Cancer Res on June 01, 2003
Involvement of human MOF in ATM function. Mol Cell Biol (2005) 2.30
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). Mol Cell Biol (2006) 2.02
Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. Mol Cell Biol (2008) 1.48
Nonhistone protein acetylation as cancer therapy targets. Expert Rev Anticancer Ther (2010) 1.45
Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer. Future Oncol (2011) 1.34
Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization. Biochem J (2004) 1.17
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. Oncogene (2008) 1.15
Radiosensitization of colorectal carcinoma cell lines by histone deacetylase inhibition. Radiat Oncol (2006) 1.13
Relaxed repression of herpes simplex virus type 1 genomes in Murine trigeminal neurons. J Virol (2007) 1.08
The cellular ataxia telangiectasia-mutated kinase promotes epstein-barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli. J Virol (2012) 1.03
Activation of ATM-dependent DNA damage signal pathway by a histone deacetylase inhibitor, trichostatin A. Cancer Res Treat (2007) 0.92
Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle. J Assoc Res Otolaryngol (2009) 0.88
ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate. Biochem Biophys Res Commun (2007) 0.88
Effectiveness of the histone deacetylase inhibitor (S)-2 against LNCaP and PC3 human prostate cancer cells. PLoS One (2013) 0.85
Combined treatment with low concentrations of decitabine and SAHA causes cell death in leukemic cell lines but not in normal peripheral blood lymphocytes. Biomed Res Int (2013) 0.82
Class I HDACs Affect DNA Replication, Repair, and Chromatin Structure: Implications for Cancer Therapy. Antioxid Redox Signal (2014) 0.82
Mode of interaction between butyroyloxymethyl-diethyl phosphate (AN-7) and doxorubicin in MCF-7 and resistant MCF-7/Dx cell lines. J Cancer Res Clin Oncol (2006) 0.81
Suberoylanilide hydroxyamic acid modification of chromatin architecture affects DNA break formation and repair. Int J Radiat Oncol Biol Phys (2010) 0.78
The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo. Oncotarget (2017) 0.77
Histone deacetylase inhibitor: antineoplastic agent and radiation modulator. Adv Exp Med Biol (2011) 0.77
Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget (2016) 0.75
Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C. BMC Mol Biol (2016) 0.75
Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation. Adv Prev Med (2016) 0.75
DNA damage, homology-directed repair, and DNA methylation. PLoS Genet (2007) 2.29
Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev (2005) 1.52
Endogenous assays of DNA methyltransferases: Evidence for differential activities of DNMT1, DNMT2, and DNMT3 in mammalian cells in vivo. Mol Cell Biol (2003) 1.32
DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair. J Biol Chem (2010) 0.95
SUMOylation enhances DNA methyltransferase 1 activity. Biochem J (2009) 0.94
DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase. J Biol Chem (2004) 0.93
Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status. Proc Natl Acad Sci U S A (2002) 0.89
Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage. PLoS One (2012) 0.86
Syntheses and biological activities of rebeccamycin analogues with uncommon sugars. J Med Chem (2005) 0.86
Targeted DNA methylation by homology-directed repair in mammalian cells. Transcription reshapes methylation on the repaired gene. Nucleic Acids Res (2013) 0.86
GADD45α inhibition of DNMT1 dependent DNA methylation during homology directed DNA repair. Nucleic Acids Res (2011) 0.85
Differentiation linked regulation of telomerase activity by Makorin-1. Mol Cell Biochem (2010) 0.85
Telomeric DNA damage by topoisomerase I. A possible mechanism for cell killing by camptothecin. J Biol Chem (2004) 0.84
Syntheses and biological activities of disaccharide daunorubicins. J Med Chem (2005) 0.83
Gold(III) macrocycles: nucleotide-specific unconventional catalytic inhibitors of human topoisomerase I. J Am Chem Soc (2014) 0.83
Down modulation of topoisomerase I affects DNA repair efficiency. DNA Repair (Amst) (2003) 0.80
Prostate cancer cell surface-associated keratin 8 and its implications for enhanced plasmin activity. Protein J (2012) 0.79
Gold(III) complexes of pyridyl- and isoquinolylamido ligands: structural, spectroscopic, and biological studies of a new class of dual topoisomerase I and II inhibitors. Inorg Chem (2013) 0.78
New therapeutic perspectives in CCDC6 deficient lung cancer cells. Int J Cancer (2014) 0.78
A solid phase assay for topoisomerase I interfacial poisons and catalytic inhibitors. Anal Biochem (2011) 0.76
Correction: DNA Damage, Homology-Directed Repair, and DNA Methylation. PLoS Genet (2017) 0.75