PubRank

Lorenz Studer

Author PubWeight™ 138.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol 2009 13.16
2 Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011 7.90
3 Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A 2004 7.51
4 Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009 7.04
5 Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev 2008 5.34
6 Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nat Biotechnol 2007 3.48
7 Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 2003 3.43
8 Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem Cells 2007 3.11
9 Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS Med 2005 3.04
10 Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A 2009 2.86
11 Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell 2013 2.74
12 Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Nat Med 2007 2.61
13 Parthenogenetic stem cells in nonhuman primates. Science 2002 2.54
14 Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol 2010 2.54
15 Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell Stem Cell 2013 2.51
16 Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells. Nat Biotechnol 2010 2.43
17 miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell Stem Cell 2011 2.33
18 Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature 2012 2.32
19 Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell 2013 2.31
20 BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem Cells 2009 2.22
21 Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nat Biotechnol 2012 2.09
22 Derivation of neural crest cells from human pluripotent stem cells. Nat Protoc 2010 2.05
23 Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell 2010 2.02
24 Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling. Nat Commun 2011 1.84
25 A poised chromatin platform for TGF-β access to master regulators. Cell 2011 1.81
26 High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2008 1.79
27 Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nat Biotechnol 2012 1.74
28 Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environ Health Perspect 2012 1.70
29 Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol 2003 1.64
30 Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem Cells 2005 1.56
31 Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library. Stem Cells 2006 1.55
32 Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes Dev 2011 1.55
33 Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nat Biotechnol 2005 1.54
34 Therapeutic cloning in individual parkinsonian mice. Nat Med 2008 1.46
35 Cell fate plug and play: direct reprogramming and induced pluripotency. Cell 2011 1.42
36 Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. J Clin Invest 2012 1.40
37 Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 2009 1.39
38 Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. J Neurosci 2010 1.36
39 Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell Rep 2013 1.36
40 Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft. Eur J Neurosci 2006 1.32
41 Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells. Cell Growth Differ 2002 1.22
42 The expanding role of miR-302-367 in pluripotency and reprogramming. Cell Cycle 2012 1.13
43 Induced pluripotent stem cell technology for the study of human disease. Nat Methods 2010 1.09
44 Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain 2008 1.06
45 Maturation of spinal motor neurons derived from human embryonic stem cells. PLoS One 2012 1.04
46 ZFX controls the self-renewal of human embryonic stem cells. PLoS One 2012 1.03
47 Making and repairing the mammalian brain--in vitro production of dopaminergic neurons. Semin Cell Dev Biol 2003 1.02
48 Dopaminergic neuronal differentiation from rat embryonic neural precursors by Nurr1 overexpression. J Neurochem 2003 1.01
49 Adapting human pluripotent stem cells to high-throughput and high-content screening. Nat Protoc 2012 0.97
50 Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL. J Neurosci 2004 0.96
51 Optical bioluminescence imaging of human ES cell progeny in the rodent CNS. J Neurochem 2007 0.92
52 Cellular reprogramming: recent advances in modeling neurological diseases. J Neurosci 2011 0.92
53 Single-molecule analysis reveals changes in the DNA replication program for the POU5F1 locus upon human embryonic stem cell differentiation. Mol Cell Biol 2010 0.92
54 Modelling familial dysautonomia in human induced pluripotent stem cells. Philos Trans R Soc Lond B Biol Sci 2011 0.92
55 Embryonic stem cell-derived neurons form functional networks in vitro. Stem Cells 2006 0.91
56 Converting human pluripotent stem cells to neural tissue and neurons to model neurodegeneration. Methods Mol Biol 2011 0.91
57 Transcriptional program of bone morphogenetic protein-2-induced epithelial and smooth muscle differentiation of pluripotent human embryonal carcinoma cells. Funct Integr Genomics 2005 0.87
58 Protocols for generating ES cell-derived dopamine neurons. Adv Exp Med Biol 2009 0.86
59 Acquisition of in vitro and in vivo functionality of Nurr1-induced dopamine neurons. FASEB J 2006 0.86
60 Dual-SMAD Inhibition/WNT Activation-Based Methods to Induce Neural Crest and Derivatives from Human Pluripotent Stem Cells. Methods Mol Biol 2016 0.84
61 Constitutive gene expression predisposes morphogen-mediated cell fate responses of NT2/D1 and 27X-1 human embryonal carcinoma cells. Stem Cells 2006 0.82
62 Mesenchymal cells. Methods Enzymol 2006 0.81
63 Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice. Stem Cells Transl Med 2013 0.79
64 Aging in iPS cells. Aging (Albany NY) 2014 0.78
65 Wnt1 overexpression leads to enforced cardiomyogenesis and inhibition of hematopoiesis in murine embryonic stem cells. Stem Cells Dev 2010 0.78
66 Build-a-brain. Cell Stem Cell 2013 0.78
67 Enriched motor neuron populations derived from bacterial artificial chromosome-transgenic human embryonic stem cells. Clin Neurosurg 2009 0.77
68 New ISSCR guidelines: clinical translation of stem cell research. Lancet 2016 0.77
69 Neuroscience: Excessive mobility interrupted. Nature 2010 0.76
70 IPSCs put to the test. Nat Biotechnol 2011 0.75
71 Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors. PLoS One 2016 0.75
72 Too much Sonic, too few neurons. Nat Neurosci 2009 0.75
73 815 Human Embryonic Stem Cells: In Vivo Behavior after Grafting in the Rodent Brain. Neurosurgery 2005 0.75
74 Therapeutic Cloning in Mice 879. Neurosurgery 2006 0.75