Published in J Neurochem on June 01, 2003
Cooperative transcription activation by Nurr1 and Pitx3 induces embryonic stem cell maturation to the midbrain dopamine neuron phenotype. Proc Natl Acad Sci U S A (2006) 1.69
Stromal cell-derived inducing activity, Nurr1, and signaling molecules synergistically induce dopaminergic neurons from mouse embryonic stem cells. Stem Cells (2005) 1.22
Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation. Eur J Neurosci (2004) 1.18
MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model. PLoS One (2011) 1.09
Transient differentiation of adult human bone marrow cells into neuron-like cells in culture: development of morphological and biochemical traits is mediated by different molecular mechanisms. Stem Cells Dev (2004) 1.01
Midbrain dopaminergic neuron fate specification: Of mice and embryonic stem cells. Mol Brain (2008) 0.96
Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant. Stem Cells (2009) 0.92
Conditions for tumor-free and dopamine neuron-enriched grafts after transplanting human ES cell-derived neural precursor cells. Mol Ther (2009) 0.89
Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy. Stem Cells Int (2012) 0.83
Midbrain dopaminergic development in vivo and in vitro from embryonic stem cells. J Anat (2005) 0.81
Nurr1 represses tyrosine hydroxylase expression via SIRT1 in human neural stem cells. PLoS One (2013) 0.79
Overexpression of basic helix-loop-helix transcription factors enhances neuronal differentiation of fetal human neural progenitor cells in various ways. Stem Cells Dev (2011) 0.79
Restriction of neural precursor ability to respond to Nurr1 by early regional specification. PLoS One (2012) 0.78
Expression patterns of Nurr1 in rat retina development. J Mol Histol (2012) 0.77
Neurological disorders and neural regeneration, with special reference to Parkinson's disease and cerebral ischemia. J Artif Organs (2009) 0.77
In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns. Exp Mol Med (2017) 0.75
BINDING SITE ANALYSIS OF THE CAENORHABDITIS ELEGANS NR4A NUCLEAR RECEPTOR NHR-6 DURING DEVELOPMENT. Nucl Receptor Res (2017) 0.75
Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner. J Biomed Sci (2017) 0.75
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol (2009) 13.16
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell (2009) 10.52
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature (2011) 7.90
Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A (2004) 7.51
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature (2009) 7.04
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature (2002) 6.51
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes Dev (2008) 5.34
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry (2011) 3.62
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nat Biotechnol (2007) 3.48
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol (2003) 3.43
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem Cells (2007) 3.11
Derivation of multipotent mesenchymal precursors from human embryonic stem cells. PLoS Med (2005) 3.04
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A (2009) 2.86
Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell (2013) 2.74
Derivation of engraftable skeletal myoblasts from human embryonic stem cells. Nat Med (2007) 2.61
Parthenogenetic stem cells in nonhuman primates. Science (2002) 2.54
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent. Nat Biotechnol (2010) 2.54
Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination. Cell Stem Cell (2013) 2.51
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells. Nat Biotechnol (2010) 2.43
miR-371-3 expression predicts neural differentiation propensity in human pluripotent stem cells. Cell Stem Cell (2011) 2.33
Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells. Nature (2012) 2.32
Human iPSC-based modeling of late-onset disease via progerin-induced aging. Cell Stem Cell (2013) 2.31
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease. J Clin Invest (2011) 2.23
Statistical tests for identifying differentially expressed genes in time-course microarray experiments. Bioinformatics (2003) 2.22
BAC transgenesis in human embryonic stem cells as a novel tool to define the human neural lineage. Stem Cells (2009) 2.22
Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors. Nat Biotechnol (2012) 2.09
Derivation of neural crest cells from human pluripotent stem cells. Nat Protoc (2010) 2.05
Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell (2010) 2.02
Safety evaluation of freehand lateral mass screw fixation in the subaxial cervical spine: evaluation of 1256 screws. Spine (Phila Pa 1976) (2015) 1.98
Decreased expression of synapse-related genes and loss of synapses in major depressive disorder. Nat Med (2012) 1.97
Evaluation of normalization methods for microarray data. BMC Bioinformatics (2003) 1.97
In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons. J Neurochem (2005) 1.86
Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling. Nat Commun (2011) 1.84
A poised chromatin platform for TGF-β access to master regulators. Cell (2011) 1.81
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell (2008) 1.79
Clinical outcomes of 3 fusion methods through the posterior approach in the lumbar spine. Spine (Phila Pa 1976) (2006) 1.78
Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J Biol Chem (2005) 1.75
Large-scale screening using familial dysautonomia induced pluripotent stem cells identifies compounds that rescue IKBKAP expression. Nat Biotechnol (2012) 1.74
Fibroblast growth factor 20 polymorphisms and haplotypes strongly influence risk of Parkinson disease. Am J Hum Genet (2004) 1.70
Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells. Environ Health Perspect (2012) 1.70
Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol (2003) 1.64
Long-term survival of dopamine neurons derived from parthenogenetic primate embryonic stem cells (cyno-1) after transplantation. Stem Cells (2005) 1.56
The quantitative analysis of tissue injury markers after mini-open lumbar fusion. Spine (Phila Pa 1976) (2006) 1.55
Production of green fluorescent protein transgenic embryonic stem cells using the GENSAT bacterial artificial chromosome library. Stem Cells (2006) 1.55
Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes Dev (2011) 1.55
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nat Biotechnol (2005) 1.54
Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway. Cell Stem Cell (2009) 1.51
Progestin re-treatment in patients with recurrent endometrial adenocarcinoma after successful fertility-sparing management using progestin. Gynecol Oncol (2012) 1.49
Therapeutic cloning in individual parkinsonian mice. Nat Med (2008) 1.46
Adult hippocampal neurogenesis and related neurotrophic factors. BMB Rep (2009) 1.44
Cell fate plug and play: direct reprogramming and induced pluripotency. Cell (2011) 1.42
Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment. J Clin Invest (2012) 1.40
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev (2009) 1.39
Pneumoretroperitoneum following acupuncture: is the pneumoretroperitoneum really developed after acupuncture? J Altern Complement Med (2009) 1.38
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. J Neurosci (2010) 1.36
Modeling neural crest induction, melanocyte specification, and disease-related pigmentation defects in hESCs and patient-specific iPSCs. Cell Rep (2013) 1.36
Outcome of pedicle subtraction osteotomies for fixed sagittal imbalance of multiple etiologies: a retrospective review of 140 patients. Spine (Phila Pa 1976) (2012) 1.36
Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter. Neurochem Res (2004) 1.35
Lithium selectively increases neuronal differentiation of hippocampal neural progenitor cells both in vitro and in vivo. J Neurochem (2004) 1.35
Significance of chin-brow vertical angle in correction of kyphotic deformity of ankylosing spondylitis patients. Spine (Phila Pa 1976) (2003) 1.33
Transplanted dopamine neurons derived from primate ES cells preferentially innervate DARPP-32 striatal progenitors within the graft. Eur J Neurosci (2006) 1.32
Mycobacterium abscessus activates the macrophage innate immune response via a physical and functional interaction between TLR2 and dectin-1. Cell Microbiol (2008) 1.30
Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons. J Neurochem (2007) 1.29
Comprehensive transcriptome analysis of differentiation of embryonic stem cells into midbrain and hindbrain neurons. Dev Biol (2004) 1.24
Sagittal alignment of the cervical spine after the laminoplasty. Spine (Phila Pa 1976) (2007) 1.22
Inhibition of pluripotent stem cell-derived teratoma formation by small molecules. Proc Natl Acad Sci U S A (2013) 1.22
Expression profiling of lineage differentiation in pluripotential human embryonal carcinoma cells. Cell Growth Differ (2002) 1.22
Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation. Exp Cell Res (2003) 1.22
Nuclear factor-kappaB activation correlates with better prognosis and Akt activation in human gastric cancer. Clin Cancer Res (2005) 1.22
The role of temporal structure in human vision. Behav Cogn Neurosci Rev (2005) 1.22
Effect of ablated hippocampal neurogenesis on the formation and extinction of contextual fear memory. Mol Brain (2009) 1.21
New dimensions of interneuronal specialization unmasked by principal cell heterogeneity. Trends Neurosci (2011) 1.20
Regulation of fast-spiking basket cell synapses by the chloride channel ClC-2. Nat Neurosci (2010) 1.18
Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers. Cancer Sci (2003) 1.18
Use of SAGE technology to reveal changes in gene expression in Arabidopsis leaves undergoing cold stress. Plant Mol Biol (2003) 1.17
The expanding role of miR-302-367 in pluripotency and reprogramming. Cell Cycle (2012) 1.13
Cancer prevention interdisciplinary education program at Purdue University: overview and preliminary results. J Cancer Educ (2011) 1.11
Induced pluripotent stem cell technology for the study of human disease. Nat Methods (2010) 1.09
Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5Y cells. Toxicol Lett (2009) 1.09
Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells. Biochem Biophys Res Commun (2002) 1.08
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. Hum Mol Genet (2013) 1.08
Lithium enhances long-term potentiation independently of hippocampal neurogenesis in the rat dentate gyrus. J Neurochem (2003) 1.07
Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation. Neuropharmacology (2008) 1.06
The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research. Nat Biotechnol (2005) 1.06
Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease. Brain (2008) 1.06
Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival. Stem Cells (2010) 1.06