Published in Science on June 06, 2003
Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat Neurosci (2005) 4.25
The itty-bitty time machine genetics of the cyanobacterial circadian clock. Adv Genet (2011) 1.15
The suprachiasmatic nucleus is a functionally heterogeneous timekeeping organ. Methods Enzymol (2005) 1.11
Experimental 'jet lag' inhibits adult neurogenesis and produces long-term cognitive deficits in female hamsters. PLoS One (2010) 1.01
Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium. J Circadian Rhythms (2007) 1.01
A model for generating circadian rhythm by coupling ultradian oscillators. Theor Biol Med Model (2006) 0.83
Life, Information, Entropy, and Time: Vehicles for Semantic Inheritance. Complexity (2007) 0.81
Light entrainment of the murine intraocular pressure circadian rhythm utilizes non-local mechanisms. PLoS One (2017) 0.75
Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat Neurosci (2005) 4.25
Circadian rhythms in isolated brain regions. J Neurosci (2002) 3.82
Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging. Neuron (2008) 2.73
A circadian clock in macrophages controls inflammatory immune responses. Proc Natl Acad Sci U S A (2009) 2.71
The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system. J Neurosci (2004) 2.42
Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster. Proc Natl Acad Sci U S A (2002) 2.33
PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors. Neuron (2005) 2.30
The imprinted gene Magel2 regulates normal circadian output. Nat Genet (2007) 2.18
Come together, right...now: synchronization of rhythms in a mammalian circadian clock. Neuron (2005) 2.17
Organization of the Drosophila circadian control circuit. Curr Biol (2008) 2.11
Clock genes, oscillators, and cellular networks in the suprachiasmatic nuclei. J Biol Rhythms (2004) 2.07
Forced desynchronization of dual circadian oscillators within the rat suprachiasmatic nucleus. Curr Biol (2004) 1.97
Photic and circadian expression of luciferase in mPeriod1-luc transgenic mice invivo. Proc Natl Acad Sci U S A (2001) 1.96
Tracking the seasons: the internal calendars of vertebrates. Philos Trans R Soc Lond B Biol Sci (2008) 1.78
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab (2013) 1.74
Reevaluation of Drosophila melanogaster's neuronal circadian pacemakers reveals new neuronal classes. J Comp Neurol (2006) 1.71
Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons. Proc Natl Acad Sci U S A (2009) 1.70
Myelination and long diffusion times alter diffusion-tensor-imaging contrast in myelin-deficient shiverer mice. Neuroimage (2005) 1.64
GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons. Proc Natl Acad Sci U S A (2006) 1.62
Circadian rhythm generation and entrainment in astrocytes. J Neurosci (2005) 1.59
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. J Clin Invest (2013) 1.57
The bHLH protein Dimmed controls neuroendocrine cell differentiation in Drosophila. Development (2003) 1.55
A molecular model for intercellular synchronization in the mammalian circadian clock. Biophys J (2007) 1.54
Mapping peptidergic cells in Drosophila: where DIMM fits in. PLoS One (2008) 1.51
SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J Neurosci (2010) 1.51
PDF receptor expression reveals direct interactions between circadian oscillators in Drosophila. J Comp Neurol (2010) 1.41
Circadian regulation of ATP release in astrocytes. J Neurosci (2011) 1.41
The suprachiasmatic nucleus entrains, but does not sustain, circadian rhythmicity in the olfactory bulb. J Neurosci (2004) 1.39
Olfactory bulb neurons express functional, entrainable circadian rhythms. Eur J Neurosci (2004) 1.27
Regulators acting in combinatorial codes also act independently in single differentiating neurons. Neuron (2005) 1.26
Minireview: timely ovulation: circadian regulation of the female hypothalamo-pituitary-gonadal axis. Endocrinology (2005) 1.25
In search of the pathways for light-induced pacemaker resetting in the suprachiasmatic nucleus. J Biol Rhythms (2003) 1.25
A circadian clock in the olfactory bulb controls olfactory responsivity. J Neurosci (2006) 1.24
A novel diuretic hormone receptor in Drosophila: evidence for conservation of CGRP signaling. J Exp Biol (2005) 1.24
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B. PLoS One (2007) 1.23
Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro. J Neurosci (2005) 1.22
Lateralization of circadian pacemaker output: Activation of left- and right-sided luteinizing hormone-releasing hormone neurons involves a neural rather than a humoral pathway. J Neurosci (2003) 1.20
Identification of Drosophila neuropeptide receptors by G protein-coupled receptors-beta-arrestin2 interactions. J Biol Chem (2003) 1.20
Plasticity of circadian behavior and the suprachiasmatic nucleus following exposure to non-24-hour light cycles. J Biol Rhythms (2004) 1.20
Chronobiology by moonlight. Proc Biol Sci (2013) 1.19
A neuropeptide speeds circadian entrainment by reducing intercellular synchrony. Proc Natl Acad Sci U S A (2013) 1.19
The Drosophila basic helix-loop-helix protein DIMMED directly activates PHM, a gene encoding a neuropeptide-amidating enzyme. Mol Cell Biol (2007) 1.16
Therapeutic efficacy of bone marrow transplant, intracranial AAV-mediated gene therapy, or both in the mouse model of MPS IIIB. Mol Ther (2010) 1.16
RNA-interference knockdown of Drosophila pigment dispersing factor in neuronal subsets: the anatomical basis of a neuropeptide's circadian functions. PLoS One (2009) 1.14
Vasoactive intestinal polypeptide requires parallel changes in adenylate cyclase and phospholipase C to entrain circadian rhythms to a predictable phase. J Neurophysiol (2011) 1.14
GABA networks destabilize genetic oscillations in the circadian pacemaker. Neuron (2013) 1.12
PDFR and CRY signaling converge in a subset of clock neurons to modulate the amplitude and phase of circadian behavior in Drosophila. PLoS One (2011) 1.12
Training scientists in a science center improves science communication to the public. Adv Physiol Educ (2012) 1.11
The suprachiasmatic nucleus is a functionally heterogeneous timekeeping organ. Methods Enzymol (2005) 1.11
Small-world network models of intercellular coupling predict enhanced synchronization in the suprachiasmatic nucleus. J Biol Rhythms (2009) 1.11
Transcriptional orchestration of the regulated secretory pathway in neurons by the bHLH protein DIMM. Curr Biol (2009) 1.10
Ap-let neurons--a peptidergic circuit potentially controlling ecdysial behavior in Drosophila. Dev Biol (2004) 1.05
Wavelet measurement suggests cause of period instability in mammalian circadian neurons. J Biol Rhythms (2011) 1.04
Intracellular and intercellular processes determine robustness of the circadian clock. FEBS Lett (2011) 1.02
The circadian neuropeptide PDF signals preferentially through a specific adenylate cyclase isoform AC3 in M pacemakers of Drosophila. PLoS Biol (2012) 1.01
Scaling factors: transcription factors regulating subcellular domains. Bioessays (2011) 1.01
Wavelet meets actogram. J Biol Rhythms (2013) 1.01
Molecular organization of Drosophila neuroendocrine cells by Dimmed. Curr Biol (2011) 1.00
In search of a temporal niche: social interactions. Prog Brain Res (2012) 1.00
Continuous delivery of D-luciferin by implanted micro-osmotic pumps enables true real-time bioluminescence imaging of luciferase activity in vivo. Mol Imaging (2007) 0.98
Socially synchronized circadian oscillators. Proc Biol Sci (2013) 0.98
Weakly circadian cells improve resynchrony. PLoS Comput Biol (2012) 0.97
Lithium- and valproate-induced alterations in circadian locomotor behavior in Drosophila. Neuropsychopharmacology (2005) 0.97
Peptidergic neurosecretory cells in insects: organization and control by the bHLH protein DIMMED. Gen Comp Endocrinol (2008) 0.96
Drosophila CG8422 encodes a functional diuretic hormone receptor. J Exp Biol (2004) 0.96
A neural clockwork for encoding circadian time. J Appl Physiol (1985) (2002) 0.96
Spatiotemporal distribution of vasoactive intestinal polypeptide receptor 2 in mouse suprachiasmatic nucleus. J Comp Neurol (2012) 0.95
c-Fos expression in the brains of behaviorally "split" hamsters in constant light: calling attention to a dorsolateral region of the suprachiasmatic nucleus and the medial division of the lateral habenula. J Biol Rhythms (2005) 0.94
Daily rhythms in olfactory discrimination depend on clock genes but not the suprachiasmatic nucleus. J Biol Rhythms (2011) 0.94
Bioluminescence imaging of period1 gene expression in utero. Mol Imaging (2007) 0.93
Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes. PLoS One (2009) 0.93
Vasoactive intestinal polypeptide entrains circadian rhythms in astrocytes. J Biol Rhythms (2009) 0.92
Modeling the behavior of coupled cellular circadian oscillators in the suprachiasmatic nucleus. J Biol Rhythms (2007) 0.91
Animal clocks: when science meets nature. Proc Biol Sci (2013) 0.90
Drosophila uses two distinct neuropeptide amidating enzymes, dPAL1 and dPAL2. J Neurochem (2004) 0.89
Bioluminescence imaging captures the expression and dynamics of endogenous p21 promoter activity in living mice and intact cells. Mol Cell Biol (2011) 0.87
Widely distributed Drosophila G-protein-coupled receptor (CG7887) is activated by endogenous tachykinin-related peptides. J Neurobiol (2006) 0.87
Identification and characterization of a G protein-coupled receptor for the neuropeptide proctolin in Drosophilamelanogaster. Proc Natl Acad Sci U S A (2003) 0.87
Hamsters running on time: is the lateral habenula a part of the clock? Chronobiol Int (2006) 0.87
Social forces can impact the circadian clocks of cohabiting hamsters. Proc Biol Sci (2014) 0.86
A role for the habenula in the regulation of locomotor activity cycles. Eur J Neurosci (2011) 0.86
I(A) channels encoded by Kv1.4 and Kv4.2 regulate neuronal firing in the suprachiasmatic nucleus and circadian rhythms in locomotor activity. J Neurosci (2012) 0.86
Intermediate-duration day lengths unmask reproductive responses to nonphotic environmental cues. Am J Physiol Regul Integr Comp Physiol (2009) 0.85
Multicellular model for intercellular synchronization in circadian neural networks. Biophys J (2011) 0.85
Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev (2010) 0.84
Mechanism of bilateral communication in the suprachiasmatic nucleus. Eur J Neurosci (2013) 0.84
Using Per gene expression to search for photoperiodic oscillators in the hamster suprachiasmatic nucleus. Brain Res Mol Brain Res (2004) 0.83
A subpopulation of efferent neurons in the mouse suprachiasmatic nucleus is also light responsive. Neuroreport (2002) 0.83
Design principles for phase-splitting behaviour of coupled cellular oscillators: clues from hamsters with 'split' circadian rhythms. J R Soc Interface (2008) 0.83
Photic desynchronization of two subgroups of circadian oscillators in a network model of the suprachiasmatic nucleus with dispersed coupling strengths. PLoS One (2012) 0.81
Embryonic stem cell rescue of tremor and ataxia in myelin-deficient shiverer mice. J Neurol Sci (2008) 0.80
Transcription-based oscillator model for light-induced splitting as antiphase circadian gene expression in the suprachiasmatic nuclei. J Biol Rhythms (2012) 0.80
Oxytocin in the circadian timing of birth. PLoS One (2007) 0.80
PER1-like immunoreactivity in oxytocin cells of the hamster hypothalamo-neurohypophyseal system. J Biol Rhythms (2007) 0.80
E and M circadian pacemaker neurons use different PDF receptor signalosome components in drosophila. J Biol Rhythms (2013) 0.80
Transplanted clonal neural stem-like cells respond to remote photic stimulation following incorporation within the suprachiasmatic nucleus. Exp Neurol (2002) 0.79
The clock in the brain: neurons, glia, and networks in daily rhythms. Handb Exp Pharmacol (2013) 0.79
The clock shop: coupled circadian oscillators. Exp Neurol (2012) 0.78