D W McVicar

Author PubWeight™ 47.65‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science 1992 5.94
2 Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 1994 3.46
3 Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 1994 3.31
4 Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP. Proc Natl Acad Sci U S A 2000 2.80
5 Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes. Proc Natl Acad Sci U S A 1994 1.84
6 Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12. J Exp Med 1995 1.78
7 Mutation of Tec family kinases alters T helper cell differentiation. Nat Immunol 2001 1.63
8 Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation. Proc Natl Acad Sci U S A 1992 1.55
9 Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines. J Exp Med 1993 1.53
10 Tec family kinases modulate thresholds for thymocyte development and selection. J Exp Med 2000 1.41
11 Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2. Blood 2000 1.31
12 The ever-expanding Ly49 gene family: repertoire and signaling. Immunol Rev 2001 1.26
13 A role for protein tyrosine kinase activity in natural cytotoxicity as well as antibody-dependent cellular cytotoxicity. Effects of herbimycin A. J Immunol 1992 1.17
14 Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7. J Exp Med 1995 1.14
15 Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors: binding and signaling of MCP3 through shared as well as unique receptors on monocytes and neutrophils. Eur J Immunol 1995 1.12
16 Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H. J Leukoc Biol 1999 1.08
17 Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction. J Immunol 1998 1.06
18 Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2. Blood 1995 1.01
19 Intralesional infusion of lymphokine-activated killer (LAK) cells and recombinant interleukin-2 (rIL-2) for the treatment of patients with malignant brain tumor. Neurosurgery 1988 0.99
20 Functional association of FcepsilonRIgamma with arginine(632) of paired immunoglobulin-like receptor (PIR)-A3 in murine macrophages. Blood 1999 0.97
21 Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID). J Immunol 1994 0.94
22 Regulation of JAK3 expression and activation in human B cells and B cell malignancies. J Immunol 1995 0.93
23 Differential tyrosine phosphorylation of inhibitory versus activating Ly-49 receptor proteins and their recruitment of SHP-1 phosphatase. J Immunol 1997 0.89
24 Paired inhibitory and activating receptor signals. Rev Immunogenet 2000 0.88
25 Structure/function relationship of activating Ly-49D and inhibitory Ly-49G2 NK receptors. J Immunol 1999 0.86
26 Cloning and characterization of a novel activating Ly49 closely related to Ly49A. J Immunol 1999 0.86
27 IL-4 and IL-13 induce Lsk, a Csk-like tyrosine kinase, in human monocytes. J Exp Med 1994 0.85
28 Increased proliferation, cytotoxicity, and gene expression after stimulation of human peripheral blood T lymphocytes through a surface ganglioside (GD3) J Immunol 1994 0.82
29 Regulation of NK cells through the 80-kDa TNFR (CD120b). J Leukoc Biol 1995 0.82
30 Cloning and expression of a second human natural killer cell granule tryptase, HNK-Tryp-2/granzyme 3. J Leukoc Biol 1996 0.79
31 Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-alpha. Results of a phase I clinical trial. J Neurooncol 1992 0.79
32 The Csk-like proteins Lsk, Hyl, and Matk represent the same Csk homologous kinase (Chk) and are regulated by stem cell factor in the megakaryoblastic cell line MO7e. Growth Factors 1997 0.78
33 The Csk homologous kinase, Chk, binds tyrosine phosphorylated paxillin in human blastic T cells. Biochem Biophys Res Commun 1999 0.77
34 T cell activation via the disialoganglioside GD3: analysis of signal transduction. J Leukoc Biol 1996 0.75