J Lai

Author PubWeight™ 125.37‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A motif-based profile scanning approach for genome-wide prediction of signaling pathways. Nat Biotechnol 2001 6.50
2 High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R. J Biol Chem 2000 5.18
3 Potent and nontoxic antisense oligonucleotides containing locked nucleic acids. Proc Natl Acad Sci U S A 2000 3.04
4 Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin. Pain 2001 2.05
5 Distinct potassium channels on pain-sensing neurons. Proc Natl Acad Sci U S A 2001 1.90
6 Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. J Neurosci 2001 1.76
7 Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor. J Neurosci 2001 1.72
8 Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance. J Neurosci 2000 1.71
9 Primary structure of rat cardiac beta-adrenergic and muscarinic cholinergic receptors obtained by automated DNA sequence analysis: further evidence for a multigene family. Proc Natl Acad Sci U S A 1987 1.70
10 Pronociceptive actions of dynorphin maintain chronic neuropathic pain. J Neurosci 2001 1.67
11 A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain. Proc Natl Acad Sci U S A 1999 1.66
12 Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic. Thromb Haemost 2001 1.64
13 A double-blind, placebo-controlled study of the use of amphetamine in the treatment of aphasia. Stroke 2001 1.61
14 Inducible expression of claudin-1-myc but not occludin-VSV-G results in aberrant tight junction strand formation in MDCK cells. J Cell Sci 2000 1.58
15 A faster-acting and more potent form of tissue plasminogen activator. Proc Natl Acad Sci U S A 1994 1.52
16 Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats. Pain 1999 1.43
17 Comparison of magnetic resonance imaging-fluorodeoxy- glucose positron emission tomography fusion with pathological staging in rectal cancer. Br J Surg 2010 1.41
18 Descending facilitation from the rostral ventromedial medulla maintains nerve injury-induced central sensitization. Neuroscience 2006 1.39
19 Opioid peptide receptor studies. 14. Stereochemistry determines agonist efficacy and intrinsic efficacy in the [(35)S]GTP-gamma-S functional binding assay. Synapse 2001 1.39
20 Rapid reduction of MDCK cell cholesterol by methyl-beta-cyclodextrin alters steady state transepithelial electrical resistance. Eur J Cell Biol 1999 1.37
21 Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain. Neuroscience 2003 1.35
22 A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab 2014 1.34
23 Spinal and supraspinal mechanisms of neuropathic pain. Ann N Y Acad Sci 2000 1.33
24 Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance. Br J Pharmacol 2010 1.30
25 Opioid receptor types and subtypes: the delta receptor as a model. Annu Rev Pharmacol Toxicol 1996 1.28
26 Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats. Pain 2000 1.25
27 Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain. Life Sci 2003 1.24
28 Supraspinal cholecystokinin may drive tonic descending facilitation mechanisms to maintain neuropathic pain in the rat. Pain 2000 1.23
29 Three-dimensional visualization of microvessel architecture of whole-mount tissue by confocal microscopy. Microvasc Res 2006 1.18
30 CCR2 regulates monocyte recruitment as well as CD4 T1 allorecognition after lung transplantation. Am J Transplant 2010 1.17
31 Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation. J Neurosci 2003 1.11
32 Dietary patterns as compared with physical activity in relation to metabolic syndrome among Chinese adults. Nutr Metab Cardiovasc Dis 2012 1.11
33 Nerve injury-induced tactile allodynia is mediated via ascending spinal dorsal column projections. Pain 2001 1.08
34 Characterization of the antiallodynic efficacy of morphine in a model of neuropathic pain in rats. Neuroreport 1995 1.05
35 Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain. Neuroscience 2004 1.05
36 Characterization of antinociception to opioid receptor selective agonists after antisense oligodeoxynucleotide-mediated "knock-down" of opioid receptor in vivo. J Pharmacol Exp Ther 1996 1.04
37 Best practices in EMR implementation: a systematic review. AMIA Annu Symp Proc 2006 1.04
38 Immunological properties of plaque purified strains of live attenuated respiratory syncytial virus (RSV) for human vaccine. Vaccine 1999 1.03
39 Peripheral and spinal antihyperalgesic activity of SIB-1757, a metabotropic glutamate receptor (mGLUR(5)) antagonist, in experimental neuropathic pain in rats. Neurosci Lett 2000 1.01
40 Loss of antiallodynic and antinociceptive spinal/supraspinal morphine synergy in nerve-injured rats: restoration by MK-801 or dynorphin antiserum. Brain Res 1999 1.01
41 Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene. J Neurophysiol 1997 1.00
42 Characterization of a tachykinin peptide NK2 receptor transfected into murine fibroblast B82 cells. Proc Natl Acad Sci U S A 1991 1.00
43 Simplification of high-energy collision spectra of peptides by amino-terminal derivatization. Anal Chem 1993 0.99
44 Characterization and humanization of a monoclonal antibody that neutralizes human leukocyte interferon: a candidate therapeutic for IDDM and SLE. Cytokine 2001 0.98
45 Mechanisms of referred visceral pain: uterine inflammation in the adult virgin rat results in neurogenic plasma extravasation in the skin. Pain 1997 0.97
46 A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation. Oncogene 2008 0.97
47 Changes in the biomechanical properties of neutrophils and endothelial cells during adhesion. Blood 2001 0.96
48 Spinal opioid mu receptor expression in lumbar spinal cord of rats following nerve injury. Brain Res 1998 0.96
49 Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin. Proc Natl Acad Sci U S A 1999 0.95
50 Muscarinic versus nicotinic modulation of a visual task. a pet study using drug probes. Neuropsychopharmacology 2001 0.95
51 Regulation of morphine antiallodynic efficacy by cholecystokinin in a model of neuropathic pain in rats. J Pharmacol Exp Ther 1995 0.95
52 Evolution of neurotransmitter receptor systems. Prog Neurobiol 1988 0.93
53 Selective blockade of peripheral delta opioid agonist induced antinociception by intrathecal administration of delta receptor antisense oligodeoxynucleotide. Neurosci Lett 1996 0.93
54 The new OPTN kidney allocation policy: potential for inequitable access among highly sensitized patients. Am J Transplant 2014 0.92
55 Dynorphin A elicits an increase in intracellular calcium in cultured neurons via a non-opioid, non-NMDA mechanism. J Neurophysiol 2000 0.91
56 Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: demonstration of an opioid kappa and delta inhibitory tone. J Pharmacol Exp Ther 1996 0.90
57 Mediation of spinal nerve injury induced tactile allodynia by descending facilitatory pathways in the dorsolateral funiculus in rats. Neurosci Lett 2000 0.90
58 Modification of the C terminus of cecropin is essential for broad-spectrum antimicrobial activity. Antimicrob Agents Chemother 1993 0.89
59 Sclerosing peritonitis with gross peritoneal calcification: a case report. Am J Kidney Dis 1992 0.88
60 High-affinity interaction of (des-Tyrosyl)dynorphin A(2-17) with NMDA receptors. J Pharmacol Exp Ther 1999 0.88
61 delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. Eur J Pharmacol 2000 0.88
62 Umbilical cord haematoma: a serious pregnancy complication. Aust N Z J Obstet Gynaecol 1995 0.87
63 Monoclonal antibodies against chicken brain acetylcholinesterase. Their use in immunopurification and immunochemistry to demonstrate allelic variants of the enzyme. Eur J Biochem 1987 0.87
64 Opioid peptide receptor studies. 12. Buprenorphine is a potent and selective mu/kappa antagonist in the [35S]-GTP-gamma-S functional binding assay. Synapse 1999 0.87
65 Transvaginal ultrasound diagnosis of a live twin tubal ectopic pregnancy. Australas Radiol 1999 0.87
66 Quantitative measurement of neurodegeneration in an ALS-PDC model using MR microscopy. Neuroimage 2004 0.87
67 In situ microscopic analysis of asbestos and synthetic vitreous fibers retained in hamster lungs following inhalation. Environ Health Perspect 1999 0.86
68 White blood cell count as an indicator of formaldehyde exposure. Bull Environ Contam Toxicol 1997 0.86
69 Assays of ligand-human serum albumin binding using pulsed ultrafiltration and liquid chromatography-mass spectrometry. Comb Chem High Throughput Screen 1999 0.86
70 A peptide library approach identifies a specific inhibitor for the ZAP-70 protein tyrosine kinase. Mol Cell 2000 0.84
71 Pronociceptive effects of spinal dynorphin promote cannabinoid-induced pain and antinociceptive tolerance. Pain 2002 0.84
72 Doppler sonography of adnexal masses: the predictive value of the pulsatility index in benign and malignant disease. AJR Am J Roentgenol 1994 0.83
73 There were no differences in serum HBV DNA level between HBeAg-positive and HBeAg-negative chronic hepatitis B with same liver histological necroinflammation grade but differences among grades 1, 2, 3 and 4 apportioned by the same hepatic parenchyma cell volume. J Viral Hepat 2011 0.83
74 Application of laser scanning confocal microscopy in the analysis of particle-induced pulmonary fibrosis. Toxicol Sci 1999 0.83
75 Prevalence and antimicrobial resistance of Enterococcus species of food animal origin from Beijing and Shandong Province, China. J Appl Microbiol 2012 0.82
76 Costimulatory blockade-mediated lung allograft acceptance is abrogated by overexpression of Bcl-2 in the recipient. Transplant Proc 2009 0.82
77 Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells. J Pharmacol Exp Ther 1989 0.82
78 Assessment of radiolabeled stabilized F(ab')2 fragments of monoclonal antiferritin in nude mouse model. J Nucl Med 1993 0.81
79 Regulation by prostaglandin E2 of interleukin release by T lymphocytes in mucosa. J Cell Physiol 1996 0.81
80 Low frequency chronic electrical stimulation of normal and dystrophic chicken muscle. J Physiol 1986 0.81
81 Case-control study of a HLA-G 14-bp insertion-deletion polymorphism in women with recurrent miscarriages. Scand J Immunol 2010 0.81
82 The relationship between agonist states of the M1 muscarinic receptor and the hydrolysis of inositol lipids in transfected murine fibroblast cells (B82) expressing different receptor densities. J Pharmacol Exp Ther 1989 0.81
83 Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. Brain Res 1999 0.81
84 Spontaneous growth hormone release in term infants: changes during the first four days of life. J Clin Endocrinol Metab 1993 0.81
85 Facilitated insertion of a nasogastric tube in tracheal intubated patients using the GlideScope. Br J Anaesth 2006 0.80
86 Neural control of the forms of acetylcholinesterase in slow mammalian muscles. Nature 1986 0.80
87 Selective inhibition of [D-Ala2, Glu4]deltorphin antinociception by supraspinal, but not spinal, administration of an antisense oligodeoxynucleotide to an opioid delta receptor. Life Sci 1994 0.80
88 Molecular forms of acetylcholinesterase in synaptic and extrasynaptic regions of avian tonic muscle. Neurosci Lett 1984 0.80
89 Allodynia and hyperalgesia produced by specific inhibition of spinal c-fos expression: lack of correlation with dynorphin content. J Pain 2001 0.79
90 Dynorphin-independent spinal cannabinoid antinociception. Pain 2002 0.79
91 Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception. Neuroreport 1994 0.79
92 [Study on the constituents of Marsdenia tinctoria var. tomentosa Masamune (author's transl)]. Yakugaku Zasshi 1978 0.79
93 Clinical and laboratory characteristics of systemic sclerosis patients with pulmonary arterial hypertension in China. Clin Exp Rheumatol 2014 0.79
94 Monocyte differentiation is controlled by MyD88 after mouse orthotopic lung transplantation. Transplant Proc 2009 0.78
95 Cadmium inhibits DNA strand break rejoining in methyl methanesulfonate-treated CHO-K1 cells. Toxicol Appl Pharmacol 1997 0.78
96 Can inflammation relieve pain? Nat Med 1998 0.78
97 Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor. Synapse 1998 0.77
98 Ab initio study of the electrostatic multipole nature of torsional potentials in CH3SSCH3, CH3SSH, and HOOH. Int J Quantum Chem Quantum Biol Symp 1991 0.77
99 Analysis of K-ras gene mutations in periampullary cancers, gallbladder cancers and cholangiocarcinomas from paraffin-embedded tissue sections. J Formos Med Assoc 1995 0.77
100 Oesophageal Doppler interference during abdominal ultrasound examination. Anaesthesia 1999 0.77
101 Growth in childhood thyrotoxicosis. Eur J Pediatr 1999 0.77
102 Ras(leu61) blocks differentiation of transformable 3T3 L1 and C3H10T1/2-derived preadipocytes in a dose- and time-dependent manner. Cell Growth Differ 1997 0.77
103 Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach. Eur J Histochem 2016 0.77
104 Regulation of airway muscarinic cholinergic receptor subtypes by chronic anticholinergic treatment. Mol Pharmacol 1995 0.77
105 Pharmacologic comparison of selected agonists for the M1 muscarinic receptor in transfected murine fibroblast cells (B82). J Pharmacol Exp Ther 1991 0.77
106 Colon-specific prodrugs of 5-radioiodo-2'-deoxyuridine. Acta Oncol 1996 0.76
107 Restriction fragment length polymorphism (RFLP) analysis on DNA from human compact bone. J Forensic Sci 1996 0.76
108 Fractionated radiolabeled antiferritin therapy for patients with recurrent Hodgkin's disease. Clin Cancer Res 1999 0.76
109 K(+)-stimulation of the phosphoinositide pathway in guinea-pig ileum longitudinal smooth muscle is predominantly neuronal in origin and mediated by the entry of extracellular Ca2+. Br J Pharmacol 1990 0.76
110 Cardiac fibroblasts produce leukemia inhibitory factor and endothelin, which combine to induce cardiac myocyte hypertrophy in vitro. Endocrine 1996 0.76
111 Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes. Regul Pept 1995 0.76
112 Opioid peptide receptor studies. 1. Identification of a novel delta-opioid receptor binding site in rat brain membranes. Peptides 1995 0.75
113 Selection procedures. Br Dent J 2004 0.75
114 [Relationship between the risk factors of coronary artery disease and the severity of coronary artery lesions]. Zhonghua Yi Xue Za Zhi 1998 0.75
115 [Chronic myeloid leukemia: from cytogenetics to molecular biology]. Rev Med Interne 1991 0.75
116 [Change in peripheral nervous conduction velocity in patients with occupational chronic mercury poisoning and related influencing factors]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2017 0.75
117 Pharmacological characterization of a novel muscarinic partial agonist, YM796, in transfected cells expressing the m1 or m2 muscarinic receptor gene. Life Sci 1992 0.75
118 Studies on the synthesis of vitamin B12. 2. Synthesis of the "southern" half. J Am Chem Soc 1976 0.75
119 Paraspinal ganglioneuroma in the proband of a large family with mild cutaneous manifestations of NF1, carrying a deep NF1 intronic mutation. Clin Genet 2012 0.75
120 Attenuation of gastrin-induced gastric acid secretion by antisense oligonucleotide to the CCKB/gastrin receptor. Neuroreport 1995 0.75
121 [Studies on purging leukemic cells by photosensitizer PSD-007 laser photoradiation in vitro]. Hunan Yi Ke Da Xue Xue Bao 1997 0.75
122 Frequency of molecular elimination of Ph1 clone in chronic myelogenous leukemia (CML) with interferon alpha. Leukemia 1996 0.75
123 Expression of cDNA fragment encoding sperm membrane peptide in E. coli. Mol Biol Rep 1995 0.75
124 Endovascular treatment for the spontaneous rupture of a non-aneurysmal subdiaphragmatic aorta. Vasa 2012 0.75
125 Opioid peptide receptor studies. 9. Identification of a novel non-mu- non-delta-like opioid peptide binding site in rat brain. Peptides 1998 0.75
126 Opioid peptide receptor studies. 8. One of the mouse brain deltaNCX binding sites is similar to the cloned mouse opioid delta receptor: further evidence for heterogeneity of delta opioid receptors. Peptides 1998 0.75
127 Covalent amphiphilic polyoxometalates for the design of biphasic microemulsion systems. Chem Commun (Camb) 2014 0.75
128 Increased expression of opioid delta receptors by deoxy conformation heme proteins in NG108-15 cells. Brain Res 1995 0.75
129 [Studies on the constituents of Marsdenia formosana Masamune. I. Isolation of triterpenoids and structure of marsformal (author's transl)]. Yakugaku Zasshi 1978 0.75
130 Substance P receptor expression and cellular responses to substance P in prenatal rat spinal cord cells. J Recept Signal Transduct Res 1997 0.75
131 [Hypoglycemic action of chlorella]. Taiwan Yi Xue Hui Za Zhi 1977 0.75
132 On the safety of 5-[125I]iodo-2'-deoxyuridine--Preclinical evaluation in swine. Acta Oncol 1996 0.75
133 Malignant hyperthermia. Ont Dent 1988 0.75