Published in Oncogene on June 12, 2003
Molecular targeted therapies in hepatocellular carcinoma. Hepatology (2008) 6.16
Hepatocellular carcinoma: clinical frontiers and perspectives. Gut (2014) 5.79
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet (2012) 4.07
Pathogenesis of hepatitis B virus infection. Pathol Biol (Paris) (2010) 2.48
VirusSeq: software to identify viruses and their integration sites using next-generation sequencing of human cancer tissue. Bioinformatics (2012) 1.71
Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol (2013) 1.68
Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut (2005) 1.66
Epidemiology and management of hepatocellular carcinoma. Infect Dis Clin North Am (2010) 1.58
Viruses associated with human cancer. Biochim Biophys Acta (2007) 1.47
Molecular mechanisms of human papillomavirus-induced carcinogenesis. Public Health Genomics (2009) 1.45
Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach. PLoS Genet (2012) 1.38
Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview. J Transl Med (2011) 1.33
Hepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges. Cancer Lett (2010) 1.22
Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas. PLoS One (2013) 1.19
Molecular mechanism of hepatitis B virus-induced hepatocarcinogenesis. World J Gastroenterol (2014) 1.17
Biology of SNU cell lines. Cancer Res Treat (2005) 1.11
HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress. Future Virol (2011) 1.10
Telomerase reverse transcriptase expression elevated by avian leukosis virus integration in B cell lymphomas. Proc Natl Acad Sci U S A (2007) 1.08
Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene. Protein Cell (2010) 1.07
Bacteria-human somatic cell lateral gene transfer is enriched in cancer samples. PLoS Comput Biol (2013) 1.04
Role of hepatitis B virus DNA integration in human hepatocarcinogenesis. World J Gastroenterol (2014) 0.98
Hepatocellular carcinoma: Where are we? World J Exp Med (2016) 0.92
Genome position and gene amplification. Genome Biol (2007) 0.89
Telomere and telomerase in chronic liver disease and hepatocarcinoma. World J Gastroenterol (2014) 0.85
Upregulation of human telomerase reverse transcriptase mRNA expression by in vitro transfection of hepatitis B virus X gene into human hepatocarcinoma and cholangiocarcinoma cells. World J Gastroenterol (2005) 0.84
Quasispecies structure, cornerstone of hepatitis B virus infection: mass sequencing approach. World J Gastroenterol (2013) 0.84
Detention of HPV L1 Capsid Protein and hTERC Gene in Screening of Cervical Cancer. Iran J Basic Med Sci (2013) 0.82
SummonChimera infers integrated viral genomes with nucleotide precision from NGS data. BMC Bioinformatics (2014) 0.80
Hepatocarcinogenesis associated with hepatitis B, delta and C viruses. Curr Opin Virol (2016) 0.79
Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances. F1000Res (2016) 0.78
A new, effective and high-yield approach for identifying liver tumor suppressors. Genome Med (2009) 0.78
Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis. Cytotechnology (2004) 0.78
Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data. Sci Rep (2015) 0.78
Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma. Gut Liver (2007) 0.77
A second chance for telomerase reverse transcriptase in anticancer immunotherapy. Nat Rev Clin Oncol (2016) 0.77
Hepatocellular carcinoma (HCC) recurring 10 years after clearance of hepatitis B surface antigen and 20 years after resection of hepatitis B virus-related HCC. Int J Clin Oncol (2008) 0.76
Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma. Oncotarget (2016) 0.76
Liver cell transformation in chronic HBV infection. Viruses (2009) 0.76
Human papillomavirus type 18 E6 and E7 genes integrate into human hepatoma derived cell line Hep G2. PLoS One (2012) 0.75
Avian Leukosis Virus Activation of an Antisense RNA Upstream of TERT in B-Cell Lymphomas. J Virol (2016) 0.75
Meta-Analysis of DNA Tumor-Viral Integration Site Selection Indicates a Role for Repeats, Gene Expression and Epigenetics. Cancers (Basel) (2015) 0.75
Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis. PLoS One (2015) 0.75
Update of research and management of hepatitis B. J Gastroenterol (2006) 0.75
Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma. Infect Agent Cancer (2017) 0.75
Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis (1999) 12.31
Plasmid-determined resistance to antimicrobial agents. Annu Rev Microbiol (1978) 8.35
Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology (2001) 6.88
Biliary tract cancers. N Engl J Med (1999) 6.36
Evidence for circulating bone marrow-derived endothelial cells. Blood (1998) 6.15
Chronic hepatitis B. Hepatology (2001) 5.90
FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell (1997) 5.78
Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology (1999) 5.70
Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med (2000) 5.68
Natural history of untreated nonsurgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology (1999) 5.64
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A (2001) 5.48
Surgical management of intussusception in the adult. Ann Surg (1981) 5.42
Survival in medically treated patients with homozygous beta-thalassemia. N Engl J Med (1994) 5.32
Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects. Blood (2001) 4.65
Acute hepatitis B virus infection: relation of age to the clinical expression of disease and subsequent development of the carrier state. J Infect Dis (1985) 4.47
Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability. Cancer Res (1998) 4.39
Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol Cell Biol (1997) 4.12
Complications following pancreaticoduodenectomy. Current management. Arch Surg (1992) 3.94
Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature (2000) 3.83
Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst (1999) 3.46
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1. Cancer Res (1998) 3.36
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. Nat Genet (2000) 3.33
The isolation and partial characterization of a new restriction endonuclease from Providencia stuartii. Nucleic Acids Res (1976) 3.30
Primary venous leiomyosarcoma: a rare but lethal disease. J Vasc Surg (1992) 3.05
Perioperative blood transfusion and determinants of survival after liver resection for metastatic colorectal carcinoma. Ann Surg (1992) 2.97
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res (1996) 2.89
Studies on cytochrome oxidase. Interactions of the cytochrome oxidase protein with phospholipids and cytochrome c. J Biol Chem (1975) 2.80
Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75
The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas. Am J Hum Genet (2001) 2.68
GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression. Blood (1999) 2.62
Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency. EMBO J (2001) 2.62
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology (1999) 2.56
Oxymetry deep in tissues with low-frequency electron paramagnetic resonance. Proc Natl Acad Sci U S A (1994) 2.53
Brunner's gland hamartomas: clinical presentation and pathological features of 27 cases. Am J Gastroenterol (1995) 2.52
Treatment of hepatocellular carcinoma with tamoxifen: a double-blind placebo-controlled trial in 120 patients. Gastroenterology (1995) 2.47
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41
Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res (2000) 2.38
Diagnosis and monitoring of Whipple disease by polymerase chain reaction. Ann Intern Med (1997) 2.38
Extent of high-grade dysplasia in Barrett's esophagus correlates with risk of adenocarcinoma. Gastroenterology (2001) 2.30
Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation. Gut (2002) 2.24
Is chronic hepatitis B being undertreated in the United States? J Viral Hepat (2010) 2.24
Substituted 2,5'-Bi-1H-benzimidazoles: topoisomerase I inhibition and cytotoxicity. J Med Chem (1996) 2.20
Heterogeneity in vaccine immune response: the role of immunogenetics and the emerging field of vaccinomics. Clin Pharmacol Ther (2007) 2.17
Hepatic resection for metastatic colorectal cancer results in cure for some patients. Arch Surg (1997) 2.13
PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood (2000) 2.12
Urinary symptoms and impaired quality of life in female ketamine users: persistence after cessation of use. Hong Kong Med J (2011) 2.05
Treatment of eosinophilic esophagitis with inhaled corticosteroids. J Pediatr Gastroenterol Nutr (1998) 2.05
Secular trends in the epidemiology and outcome of Barrett's oesophagus in Olmsted County, Minnesota. Gut (2001) 2.05
Direct aperture optimization: a turnkey solution for step-and-shoot IMRT. Med Phys (2002) 2.04
What prognostic factors are important in duodenal adenocarcinoma? Arch Surg (2000) 2.03
Personal and family factors associated with quality of life in adolescents with diabetes. Diabetes Care (1998) 2.02
The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference*. J Viral Hepat (2011) 2.00
Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state. Endocrinology (2001) 2.00
Transport and pharmacological properties of nine different human Na, K-ATPase isozymes. J Biol Chem (2000) 1.99
Carcinoid tumor of the appendix: treatment and prognosis. N Engl J Med (1987) 1.99
The impact of supportive counselling on women's psychological wellbeing after miscarriage--a randomised controlled trial. BJOG (2014) 1.99
Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations. Nucleic Acids Res (1998) 1.99
Activation of NF-kappa B is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes. Proc Natl Acad Sci U S A (2001) 1.99
PTEN/MMAC1 mutations identified in small cell, but not in non-small cell lung cancers. Oncogene (1998) 1.98
"Natural history" of unresected cholangiocarcinoma: patient outcome after noncurative intervention. Mayo Clin Proc (1995) 1.97
Treatment of small hepatocellular carcinoma in cirrhotic patients: a cohort study comparing surgical resection and percutaneous ethanol injection. Hepatology (1993) 1.97
Beta-blockade with propranolol and hepatic artery blood flow in patients with cirrhosis. Hepatology (1989) 1.97
Increased risk for cancer in patients with the Peutz-Jeghers syndrome. Ann Intern Med (1998) 1.96
Testicular lymphoma is associated with a high incidence of extranodal recurrence. Cancer (2000) 1.95
Hepatic steatosis as a potential risk factor for major hepatic resection. J Gastrointest Surg (1999) 1.94
Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis. J Hepatol (2001) 1.93
Effect of low proscribed blood alcohol levels (BALs) on traffic accidents among newly-licensed drivers. Med Sci Law (1986) 1.90
The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8. Proc Natl Acad Sci U S A (1998) 1.86
FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Hum Mol Genet (1996) 1.84
Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease. Hepatology (1998) 1.84
Liver transplantation for small hepatocellular carcinoma: the tumor-node-metastasis classification does not have prognostic power. Hepatology (1998) 1.83
Hepatic resection for metastatic neuroendocrine carcinomas. Am J Surg (1995) 1.82
Human papillomavirus type 16 integrations in cervical tumors frequently occur in common fragile sites. Cancer Res (2000) 1.82
Cholangiocarcinoma complicating primary sclerosing cholangitis. Ann Surg (1991) 1.78
Genetic analysis of early- versus late-stage ovarian tumors. Cancer Res (2001) 1.77
Duration of immunogenicity and efficacy of hepatitis B vaccine in a Yupik Eskimo population. JAMA (1989) 1.77
Toward a better liver graft allocation that accounts for candidates with and without hepatocellular carcinoma. Am J Transplant (2014) 1.77
Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas. Leukemia (2008) 1.75
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proc Natl Acad Sci U S A (2009) 1.75
Hepatocellular carcinoma and cirrhosis. Results of surgical treatment in a European series. Ann Surg (1996) 1.73
Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islet cell carcinomas. Cancer Res (1990) 1.72
ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J (2000) 1.72
Neuroendocrine ampullary tumors: spectrum of disease including the first report of a neuroendocrine carcinoma of non-small cell type. Surgery (1994) 1.72
Patterns of failure in grossly resected pancreatic ductal adenocarcinoma treated with adjuvant irradiation +/- 5 fluorouracil. Int J Radiat Oncol Biol Phys (1993) 1.71
Chitin utilization by marine bacteria. Degradation and catabolism of chitin oligosaccharides by Vibrio furnissii. J Biol Chem (1991) 1.70
Roles of acyl-coenzyme A:cholesterol acyltransferase-1 and -2. Curr Opin Lipidol (2001) 1.70
Sonography of acute right side colonic diverticulitis. Am J Surg (2001) 1.70
Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice. J Exp Med (2000) 1.68
Nitroglycerin improves the hemodynamic response to vasopressin in portal hypertension. Hepatology (1983) 1.67
Decreasing disability in the 21st century: the future effects of controlling six fatal and nonfatal conditions. Am J Public Health (1996) 1.67
Replacement of the inferior vena cava for malignancy: an update. J Vasc Surg (2000) 1.66
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction. Hum Mol Genet (1998) 1.65
E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer. Hum Mutat (1999) 1.65
Short-term effects of coping skills training as adjunct to intensive therapy in adolescents. Diabetes Care (1998) 1.63
Tumor necrosis factor primes hepatocytes for DNA replication in the rat. Hepatology (1998) 1.60