Down-regulation of Toll-like receptor expression in monocyte-derived Langerhans cell-like cells: implications of low-responsiveness to bacterial components in the epidermal Langerhans cells.

Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands. J Leukoc Biol (2010) 1.59

E-cadherin interactions are required for Langerhans cell differentiation. Eur J Immunol (2012) 1.45

Toll-like receptors in the skin. Semin Immunopathol (2007) 1.27

Innate immunity mediated by epidermal keratinocytes promotes acquired immunity involving Langerhans cells and T cells in the skin. Clin Exp Immunol (2007) 1.17

Toll-like receptors in skin. Adv Dermatol (2008) 1.17

Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells. Immunology (2008) 1.08

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure. Immunology (2005) 0.91

Lipoprotein-dependent and -independent immune responses to spirochetal infection. Clin Diagn Lab Immunol (2005) 0.90

TGF-beta1 treated murine dendritic cells are maturation resistant and down-regulate Toll-like receptor 4 expression. J Zhejiang Univ Sci (2004) 0.84

Inhibition of DC-SIGN-mediated transmission of human immunodeficiency virus type 1 by Toll-like receptor 3 signalling in breast milk macrophages. Immunology (2010) 0.84

Differences in T-helper polarizing capability between human monocyte-derived dendritic cells and monocyte-derived Langerhans'-like cells. Immunology (2010) 0.83

Regulation of Dendritic Cell Function in Inflammation. J Immunol Res (2015) 0.79

Inflammatory conditions distinctively alter immunological functions of Langerhans-like cells and dendritic cells in vitro. Immunology (2015) 0.77

The Cross-Talk between Spirochetal Lipoproteins and Immunity. Front Immunol (2014) 0.76

Spirochetal Lipoproteins and Immune Evasion. Front Immunol (2017) 0.75

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol (2003) 7.06

Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol (2003) 4.22

Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection. Proc Natl Acad Sci U S A (2003) 3.29

TLR3: interferon induction by double-stranded RNA including poly(I:C). Adv Drug Deliv Rev (2008) 2.72

TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta. J Biol Chem (2003) 2.61

Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors. Proc Natl Acad Sci U S A (2012) 2.61

Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J Immunol (2002) 2.57

Mitofusin 2 inhibits mitochondrial antiviral signaling. Sci Signal (2009) 2.25

Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. Biochem Biophys Res Commun (2002) 2.19

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential. Eur J Immunol (2010) 2.03

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection. J Biol Chem (2008) 1.93

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J Clin Invest (2011) 1.88

Saposin C is required for lipid presentation by human CD1b. Nat Immunol (2004) 1.88

Intelectin: a novel lipid raft-associated protein in the enterocyte brush border. Biochemistry (2006) 1.65

Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell (2012) 1.60

Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J Exp Med (2009) 1.60

A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits toll-like receptor 4-mediated cytokine production through suppression of intracellular signaling. Mol Pharmacol (2005) 1.59

CD1-mediated gamma/delta T cell maturation of dendritic cells. J Exp Med (2002) 1.56

Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guérin peptidoglycan. Infect Immun (2003) 1.55

NAK-associated protein 1 participates in both the TLR3 and the cytoplasmic pathways in type I IFN induction. J Immunol (2006) 1.54

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling. Mol Cell Biol (2011) 1.52

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection. Cell Host Microbe (2010) 1.52

Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway. J Immunol (2008) 1.50

The proinflammatory cytokine response to Chlamydia trachomatis elementary bodies in human macrophages is partly mediated by a lipoprotein, the macrophage infectivity potentiator, through TLR2/TLR1/TLR6 and CD14. J Immunol (2008) 1.46

E-cadherin interactions are required for Langerhans cell differentiation. Eur J Immunol (2012) 1.45

Toll-like receptor 3: a link between toll-like receptor, interferon and viruses. Microbiol Immunol (2004) 1.44

Frequency of alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in 19 clinical isolates of Neisseria gonorrhoeae in Tokyo in 2002. J Infect Chemother (2003) 1.43

Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells. Proc Natl Acad Sci U S A (2006) 1.42

Homo-oligomerization is essential for Toll/interleukin-1 receptor domain-containing adaptor molecule-1-mediated NF-kappaB and interferon regulatory factor-3 activation. J Biol Chem (2008) 1.33

Human herpesvirus 6 variant A but not variant B induces fusion from without in a variety of human cells through a human herpesvirus 6 entry receptor, CD46. J Virol (2002) 1.31

Differential type I IFN-inducing abilities of wild-type versus vaccine strains of measles virus. J Immunol (2007) 1.29

Mycobacterium bovis BCG cell wall and lipopolysaccharide induce a novel gene, BIGM103, encoding a 7-TM protein: identification of a new protein family having Zn-transporter and Zn-metalloprotease signatures. Genomics (2002) 1.28

Mechanism of up-regulation of human Toll-like receptor 3 secondary to infection of measles virus-attenuated strains. Biochem Biophys Res Commun (2003) 1.28

The cytoplasmic 'linker region' in Toll-like receptor 3 controls receptor localization and signaling. Int Immunol (2004) 1.28

Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation. J Immunol (2005) 1.26

C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission. Mol Immunol (2007) 1.26

Surface-expressed TLR6 participates in the recognition of diacylated lipopeptide and peptidoglycan in human cells. J Immunol (2005) 1.24

Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm. Mol Cell Biol (2003) 1.23

Adjuvant-mediated tumor regression and tumor-specific cytotoxic response are impaired in MyD88-deficient mice. Cancer Res (2004) 1.22

Sensing bacterial flagellin by membrane and soluble orthologs of Toll-like receptor 5 in rainbow trout (Onchorhynchus mikiss). J Biol Chem (2004) 1.21

Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation. J Exp Med (2010) 1.20

Teleost TLR22 recognizes RNA duplex to induce IFN and protect cells from birnaviruses. J Immunol (2008) 1.17

Activation of the human innate immune system by Spirulina: augmentation of interferon production and NK cytotoxicity by oral administration of hot water extract of Spirulina platensis. Int Immunopharmacol (2002) 1.17

Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. J Immunol (2003) 1.16

A distinct role of Riplet-mediated K63-Linked polyubiquitination of the RIG-I repressor domain in human antiviral innate immune responses. PLoS Pathog (2013) 1.16

The clathrin-mediated endocytic pathway participates in dsRNA-induced IFN-beta production. J Immunol (2008) 1.16

Prediction of the prototype of the human Toll-like receptor gene family from the pufferfish, Fugu rubripes, genome. Immunogenetics (2003) 1.16

Induction of CD1-restricted immune responses in guinea pigs by immunization with mycobacterial lipid antigens. J Immunol (2002) 1.16

Antiviral responses induced by the TLR3 pathway. Rev Med Virol (2011) 1.15

Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. J Immunol (2004) 1.15

Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein. J Virol (2012) 1.14

Mycobacterium bovis BCG cell wall-specific differentially expressed genes identified by differential display and cDNA subtraction in human macrophages. Infect Immun (2004) 1.13

Spatiotemporal mobilization of Toll/IL-1 receptor domain-containing adaptor molecule-1 in response to dsRNA. J Immunol (2007) 1.13

The extrinsic RNA-sensing pathway for adjuvant immunotherapy of cancer. Cancer Immunol Immunother (2009) 1.12

Hepatitis C virus-infected hepatocytes extrinsically modulate dendritic cell maturation to activate T cells and natural killer cells. Hepatology (2008) 1.12

Epidemiology of visceral mycoses in autopsy cases in Japan: comparison of the data from 1989, 1993, 1997, 2001, 2005 and 2007 in Annual of Pathological Autopsy Cases in Japan. Med Mycol J (2011) 1.12

Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proc Natl Acad Sci U S A (2008) 1.10

Mycolyltransferase-mediated glycolipid exchange in Mycobacteria. J Biol Chem (2008) 1.09

Cutting edge: major CD8 T cell response to live bacillus Calmette-Guérin is mediated by CD1 molecules. J Immunol (2003) 1.09