Published in Nature on June 18, 2003
Mutational processes molding the genomes of 21 breast cancers. Cell (2012) 11.22
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell (2011) 9.16
Mechanism and regulation of class switch recombination. Annu Rev Immunol (2008) 5.98
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell (2008) 4.13
Evidence for APOBEC3B mutagenesis in multiple human cancers. Nat Genet (2013) 3.94
R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters. Mol Cell (2012) 3.56
Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell (2008) 3.31
The AID/APOBEC family of nucleic acid mutators. Genome Biol (2008) 3.25
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5. Cell (2010) 2.92
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J Exp Med (2010) 2.81
Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol Cell (2011) 2.59
Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities. Nucleic Acids Res (2005) 2.43
ATM is required for efficient recombination between immunoglobulin switch regions. J Exp Med (2004) 2.30
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase. Nucleic Acids Res (2004) 2.28
PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells. Proc Natl Acad Sci U S A (2005) 2.13
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation. Nat Chem Biol (2012) 2.04
Inducible DNA breaks in Ig S regions are dependent on AID and UNG. J Exp Med (2005) 1.99
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc Natl Acad Sci U S A (2006) 1.95
The in vivo pattern of AID targeting to immunoglobulin switch regions deduced from mutation spectra in msh2-/- ung-/- mice. J Exp Med (2006) 1.92
Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes. Mol Cell (2009) 1.86
Intricate targeting of immunoglobulin somatic hypermutation maximizes the efficiency of affinity maturation. J Exp Med (2005) 1.85
Triggers for genomic rearrangements: insights into genomic, cellular and environmental influences. Nat Rev Genet (2010) 1.82
MSH2-MSH6 stimulates DNA polymerase eta, suggesting a role for A:T mutations in antibody genes. J Exp Med (2005) 1.80
Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled. Proc Natl Acad Sci U S A (2004) 1.79
Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med (2008) 1.78
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J (2005) 1.76
A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination. J Exp Med (2004) 1.76
A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat Immunol (2009) 1.68
Different mutation signatures in DNA polymerase eta- and MSH6-deficient mice suggest separate roles in antibody diversification. Proc Natl Acad Sci U S A (2005) 1.67
DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination. J Exp Med (2004) 1.59
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA. DNA Repair (Amst) (2007) 1.57
Mice deficient in APOBEC2 and APOBEC3. Mol Cell Biol (2005) 1.55
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle (2011) 1.55
Genome-wide somatic hypermutation. Proc Natl Acad Sci U S A (2004) 1.51
DNA-cytosine deaminases: from antibody maturation to antiviral defense. DNA Repair (Amst) (2004) 1.49
A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase. J Biol Chem (2009) 1.49
Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region. Mol Cell Biol (2007) 1.48
Mutations occur in the Ig Smu region but rarely in Sgamma regions prior to class switch recombination. EMBO J (2003) 1.46
Dependence of antibody gene diversification on uracil excision. J Exp Med (2007) 1.45
Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis. PLoS Pathog (2010) 1.43
G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter. Mol Cell Biol (2009) 1.43
Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. J Exp Med (2010) 1.43
Transcription induces strand-specific mutations at the 5' end of human genes. Genome Res (2008) 1.41
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination. Nat Struct Mol Biol (2010) 1.41
Examination of Msh6- and Msh3-deficient mice in class switching reveals overlapping and distinct roles of MutS homologues in antibody diversification. J Exp Med (2004) 1.41
Mechanisms of chromosomal rearrangement in the human genome. BMC Genomics (2010) 1.37
AID/APOBEC cytosine deaminase induces genome-wide kataegis. Biol Direct (2012) 1.36
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. Proc Natl Acad Sci U S A (2007) 1.34
Ubiquitylated PCNA plays a role in somatic hypermutation and class-switch recombination and is required for meiotic progression. Proc Natl Acad Sci U S A (2008) 1.32
Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops. Mol Cell Biol (2005) 1.32
DNA polymerase beta is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination. J Exp Med (2007) 1.30
Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution. J Biol Chem (2012) 1.30
Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G. Nucleic Acids Res (2012) 1.29
Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions. J Exp Med (2004) 1.29
Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination. Proc Natl Acad Sci U S A (2011) 1.27
Determinants of sequence-specificity within human AID and APOBEC3G. DNA Repair (Amst) (2010) 1.26
Interference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutation. Proc Natl Acad Sci U S A (2009) 1.23
Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions. Proc Natl Acad Sci U S A (2008) 1.20
Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination. Crit Rev Immunol (2007) 1.19
Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo. J Virol (2011) 1.18
Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA. Mol Cell Biol (2005) 1.18
DNA repair in antibody somatic hypermutation. Trends Immunol (2006) 1.17
Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase. J Biol Chem (2008) 1.16
The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination. Mol Cell Biol (2006) 1.15
Haploinsufficiency of activation-induced deaminase for antibody diversification and chromosome translocations both in vitro and in vivo. PLoS One (2008) 1.15
The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. J Exp Med (2009) 1.12
SHMTool: a webserver for comparative analysis of somatic hypermutation datasets. DNA Repair (Amst) (2008) 1.12
DNA polymerases and somatic hypermutation of immunoglobulin genes. EMBO Rep (2005) 1.12
DNA lesions and repair in immunoglobulin class switch recombination and somatic hypermutation. Ann N Y Acad Sci (2005) 1.11
Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair. Adv Immunol (2014) 1.11
AID associates with single-stranded DNA with high affinity and a long complex half-life in a sequence-independent manner. Mol Cell Biol (2006) 1.09
Mapping of a functional recombination motif that defines isotype specificity for mu-->gamma3 switch recombination implicates NF-kappaB p50 as the isotype-specific switching factor. J Exp Med (2004) 1.08
Overexpression of human DNA polymerase mu (Pol mu) in a Burkitt's lymphoma cell line affects the somatic hypermutation rate. Nucleic Acids Res (2004) 1.07
The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions. J Exp Med (2005) 1.06
V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment. Proc Natl Acad Sci U S A (2009) 1.05
DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase. Proc Natl Acad Sci U S A (2005) 1.05
Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity. J Biol Chem (2011) 1.05
Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig v in chicken B lymphocytes. PLoS Genet (2009) 1.05
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination. Proc Natl Acad Sci U S A (2004) 1.04
Disparate roles of ATR and ATM in immunoglobulin class switch recombination and somatic hypermutation. J Exp Med (2006) 1.03
Differential regulation of histone acetylation and generation of mutations in switch regions is associated with Ig class switching. Proc Natl Acad Sci U S A (2004) 1.03
Epigenetic reprogramming: is deamination key to active DNA demethylation? Reproduction (2011) 1.03
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells. Proc Natl Acad Sci U S A (2003) 1.02
Biochemical analysis of hypermutation by the deoxycytidine deaminase APOBEC3A. J Biol Chem (2012) 1.02
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. J Biol Chem (2010) 1.02
Single-stranded DNA structure and positional context of the target cytidine determine the enzymatic efficiency of AID. Mol Cell Biol (2007) 1.01
A role for the MutL mismatch repair Mlh3 protein in immunoglobulin class switch DNA recombination and somatic hypermutation. J Immunol (2006) 1.00
Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2. J Exp Med (2005) 1.00
Identification of a distinctive mutation spectrum associated with high levels of transcription in yeast. Mol Cell Biol (2004) 1.00
Codon insertion and deletion functions as a somatic diversification mechanism in human antibody repertoires. Biol Direct (2006) 0.99
Modelling mutational landscapes of human cancers in vitro. Sci Rep (2014) 0.99
Intensity of deoxycytidine deamination of HIV-1 proviral DNA by the retroviral restriction factor APOBEC3G is mediated by the noncatalytic domain. J Biol Chem (2011) 0.99
The mutation spectrum of purified AID is similar to the mutability index in Ramos cells and in ung(-/-)msh2(-/-) mice. Immunogenetics (2005) 0.98
Restricting activation-induced cytidine deaminase tumorigenic activity in B lymphocytes. Immunology (2009) 0.98
Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions. J Exp Med (2004) 0.98
Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection. Proc Natl Acad Sci U S A (2014) 0.97
Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA. Nat Struct Mol Biol (2009) 0.97
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma. PLoS One (2012) 0.96
AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Mol Immunol (2008) 0.96
Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc Natl Acad Sci U S A (2003) 4.89
APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA. Nat Struct Mol Biol (2006) 4.00
The biochemistry of somatic hypermutation. Annu Rev Immunol (2008) 3.78
A biochemically defined system for mammalian nonhomologous DNA end joining. Mol Cell (2004) 3.01
Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature (2008) 2.36
The APOBEC-2 crystal structure and functional implications for the deaminase AID. Nature (2006) 2.28
A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously. Mol Cell (2005) 2.23
SOS-induced DNA polymerases enhance long-term survival and evolutionary fitness. Proc Natl Acad Sci U S A (2002) 2.12
Biochemical analysis of hypermutational targeting by wild type and mutant activation-induced cytidine deaminase. J Biol Chem (2004) 1.90
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps. EMBO J (2007) 1.80
Fidelity of Escherichia coli DNA polymerase IV. Preferential generation of small deletion mutations by dNTP-stabilized misalignment. J Biol Chem (2002) 1.77
In vitro mutation artifacts after formalin fixation and error prone translesion synthesis during PCR. BMC Clin Pathol (2004) 1.71
Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Proc Natl Acad Sci U S A (2009) 1.64
A model for oligomeric regulation of APOBEC3G cytosine deaminase-dependent restriction of HIV. J Biol Chem (2008) 1.62
DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state. Biochemistry (2007) 1.61
Modifying the beta,gamma leaving-group bridging oxygen alters nucleotide incorporation efficiency, fidelity, and the catalytic mechanism of DNA polymerase beta. Biochemistry (2007) 1.61
AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation. Oncogene (2005) 1.60
Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase. J Am Chem Soc (2003) 1.58
Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerases. Proc Natl Acad Sci U S A (2005) 1.58
(R)-beta,gamma-fluoromethylene-dGTP-DNA ternary complex with DNA polymerase beta. J Am Chem Soc (2007) 1.48
Methylation protects cytidines from AID-mediated deamination. Mol Immunol (2005) 1.46
Error-prone replication for better or worse. Trends Microbiol (2004) 1.43
The active form of DNA polymerase V is UmuD'(2)C-RecA-ATP. Nature (2009) 1.43
Structural model for deoxycytidine deamination mechanisms of the HIV-1 inactivation enzyme APOBEC3G. J Biol Chem (2010) 1.42
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. EMBO J (2003) 1.42
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. Nature (2006) 1.34
A dynamic polymerase exchange with Escherichia coli DNA polymerase IV replacing DNA polymerase III on the sliding clamp. J Biol Chem (2008) 1.34
Alpha,beta-difluoromethylene deoxynucleoside 5'-triphosphates: a convenient synthesis of useful probes for DNA polymerase beta structure and function. Org Lett (2009) 1.34
Replication restart in UV-irradiated Escherichia coli involving pols II, III, V, PriA, RecA and RecFOR proteins. Mol Microbiol (2002) 1.32
Single-stranded DNA scanning and deamination by APOBEC3G cytidine deaminase at single molecule resolution. J Biol Chem (2012) 1.30
Exploring the role of large conformational changes in the fidelity of DNA polymerase beta. Proteins (2008) 1.29
Simulating the effect of DNA polymerase mutations on transition-state energetics and fidelity: evaluating amino acid group contribution and allosteric coupling for ionized residues in human pol beta. Biochemistry (2006) 1.28
Mutagenic effects of 2-deoxyribonolactone in Escherichia coli. An abasic lesion that disobeys the A-rule. Biochemistry (2004) 1.28
To slip or skip, visualizing frameshift mutation dynamics for error-prone DNA polymerases. J Biol Chem (2004) 1.26
Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism. J Cell Biol (2009) 1.23
Lessons from 50 years of SOS DNA-damage-induced mutagenesis. Nat Rev Mol Cell Biol (2007) 1.23
A comprehensive comparison of DNA replication past 2-deoxyribose and its tetrahydrofuran analog in Escherichia coli. Nucleic Acids Res (2004) 1.22
Halogenated beta,gamma-methylene- and ethylidene-dGTP-DNA ternary complexes with DNA polymerase beta: structural evidence for stereospecific binding of the fluoromethylene analogues. J Am Chem Soc (2010) 1.21
Effects of the C4'-oxidized abasic site on replication in Escherichia coli. An unusually large deletion is induced by a small lesion. Biochemistry (2004) 1.17
Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts. J Biol Chem (2001) 1.17
Dissecting APOBEC3G substrate specificity by nucleoside analog interference. J Biol Chem (2009) 1.17
Impact of phosphorylation and phosphorylation-null mutants on the activity and deamination specificity of activation-induced cytidine deaminase. J Biol Chem (2008) 1.16
DNA polymerase V and RecA protein, a minimal mutasome. Mol Cell (2005) 1.16
DNA polymerase fidelity: comparing direct competition of right and wrong dNTP substrates with steady state and pre-steady state kinetics. Biochemistry (2010) 1.13
Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. J Biol Chem (2003) 1.12
Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chem Res Toxicol (2008) 1.12
Computer simulation studies of the fidelity of DNA polymerases. Biopolymers (2003) 1.11
Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV. J Biol Chem (2008) 1.09
Reward versus risk: DNA cytidine deaminases triggering immunity and disease. Biochemistry (2005) 1.08
A new model for SOS-induced mutagenesis: how RecA protein activates DNA polymerase V. Crit Rev Biochem Mol Biol (2010) 1.08
V-region mutation in vitro, in vivo, and in silico reveal the importance of the enzymatic properties of AID and the sequence environment. Proc Natl Acad Sci U S A (2009) 1.05
Analysis of a single-stranded DNA-scanning process in which activation-induced deoxycytidine deaminase (AID) deaminates C to U haphazardly and inefficiently to ensure mutational diversity. J Biol Chem (2011) 1.05
Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV. J Biol Chem (2004) 1.03
DNA deaminases AID and APOBEC3G act processively on single-stranded DNA. DNA Repair (Amst) (2007) 1.02
GANP-mediated recruitment of activation-induced cytidine deaminase to cell nuclei and to immunoglobulin variable region DNA. J Biol Chem (2010) 1.02
Critical amino acids in Escherichia coli UmuC responsible for sugar discrimination and base-substitution fidelity. Nucleic Acids Res (2012) 1.01
Weak strand displacement activity enables human DNA polymerase beta to expand CAG/CTG triplet repeats at strand breaks. J Biol Chem (2002) 0.99
Mechanisms of APOBEC3G-catalyzed processive deamination of deoxycytidine on single-stranded DNA. Nat Struct Mol Biol (2009) 0.97
Simple and efficient purification of Escherichia coli DNA polymerase V: cofactor requirements for optimal activity and processivity in vitro. DNA Repair (Amst) (2012) 0.97
Roles of DNA polymerase V and RecA protein in SOS damage-induced mutation. Chem Rev (2006) 0.97
Replication of an oxidized abasic site in Escherichia coli by a dNTP-stabilized misalignment mechanism that reads upstream and downstream nucleotides. Biochemistry (2006) 0.96
Stochastic properties of processive cytidine DNA deaminases AID and APOBEC3G. Philos Trans R Soc Lond B Biol Sci (2009) 0.95
Mechanisms employed by Escherichia coli to prevent ribonucleotide incorporation into genomic DNA by Pol V. PLoS Genet (2012) 0.94
Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design. Biochim Biophys Acta (2010) 0.93
AID and Apobec3G haphazard deamination and mutational diversity. Cell Mol Life Sci (2012) 0.93
Competitive fitness during feast and famine: how SOS DNA polymerases influence physiology and evolution in Escherichia coli. Genetics (2013) 0.93
Biochemical basis of immunological and retroviral responses to DNA-targeted cytosine deamination by activation-induced cytidine deaminase and APOBEC3G. J Biol Chem (2009) 0.93
β,γ-CHF- and β,γ-CHCl-dGTP diastereomers: synthesis, discrete 31P NMR signatures, and absolute configurations of new stereochemical probes for DNA polymerases. J Am Chem Soc (2012) 0.92
The steric gate of DNA polymerase ι regulates ribonucleotide incorporation and deoxyribonucleotide fidelity. J Biol Chem (2014) 0.92
Stereospecific formation of a ternary complex of (S)-α,β-fluoromethylene-dATP with DNA pol β. Chembiochem (2012) 0.92
DNA polymerase beta catalytic efficiency mirrors the Asn279-dCTP H-bonding strength. FEBS Lett (2007) 0.92
Transition state in DNA polymerase β catalysis: rate-limiting chemistry altered by base-pair configuration. Biochemistry (2014) 0.91
APOBEC deaminases-mutases with defensive roles for immunity. Sci China C Life Sci (2009) 0.91
Escherichia coli UmuC active site mutants: effects on translesion DNA synthesis, mutagenesis and cell survival. DNA Repair (Amst) (2012) 0.89
Two distinct modes of RecA action are required for DNA polymerase V-catalyzed translesion synthesis. Proc Natl Acad Sci U S A (2002) 0.89
The essential C family DnaE polymerase is error-prone and efficient at lesion bypass. J Biol Chem (2003) 0.89
Role of high-fidelity Escherichia coli DNA polymerase I in replication bypass of a deoxyadenosine DNA-peptide cross-link. J Bacteriol (2011) 0.89
Synthesis and biological evaluation of fluorinated deoxynucleotide analogs based on bis-(difluoromethylene)triphosphoric acid. Proc Natl Acad Sci U S A (2010) 0.89
A structural basis for the biochemical behavior of activation-induced deoxycytidine deaminase class-switch recombination-defective hyper-IgM-2 mutants. J Biol Chem (2012) 0.89
Effect of β,γ-CHF- and β,γ-CHCl-dGTP halogen atom stereochemistry on the transition state of DNA polymerase β. Biochemistry (2012) 0.88
RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Proc Natl Acad Sci U S A (2013) 0.88
Hypermutation at A/T sites during G.U mismatch repair in vitro by human B-cell lysates. J Biol Chem (2008) 0.88
A biochemical analysis linking APOBEC3A to disparate HIV-1 restriction and skin cancer. J Biol Chem (2013) 0.88
A computational study of the hydrolysis of dGTP analogues with halomethylene-modified leaving groups in solution: implications for the mechanism of DNA polymerases. Biochemistry (2009) 0.86
In vitro effects of a C4'-oxidized abasic site on DNA polymerases. Biochemistry (2004) 0.86
GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy. Nat Commun (2013) 0.86
A mathematical model for scanning and catalysis on single-stranded DNA, illustrated with activation-induced deoxycytidine deaminase. J Biol Chem (2013) 0.85
First AID (activation-induced cytidine deaminase) is needed to produce high affinity isotype-switched antibodies. J Biol Chem (2006) 0.83
Resolving a fidelity paradox: why Escherichia coli DNA polymerase II makes more base substitution errors in AT- compared with GC-rich DNA. J Biol Chem (2001) 0.83
Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination. Nat Struct Mol Biol (2013) 0.82
Lentivirus restriction by diverse primate APOBEC3A proteins. Virology (2013) 0.81
Purification and characterization of Escherichia coli DNA polymerase V. Methods Enzymol (2006) 0.81
Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment. Biochemistry (2012) 0.80