Published in Biochem J on September 15, 2003
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site. Blood (2008) 2.12
The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. Blood (2011) 1.67
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex. Proc Natl Acad Sci U S A (2005) 1.64
The spectrin-ankyrin-4.1-adducin membrane skeleton: adapting eukaryotic cells to the demands of animal life. Protoplasma (2010) 1.26
Mechanical control of the sense of touch by β-spectrin. Nat Cell Biol (2014) 1.14
Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes. Proc Natl Acad Sci U S A (2006) 1.06
The transitional junction: a new functional subcellular domain at the intercalated disc. Mol Biol Cell (2006) 1.05
Structural and dynamic study of the tetramerization region of non-erythroid alpha-spectrin: a frayed helix revealed by site-directed spin labeling electron paramagnetic resonance. Biochemistry (2009) 0.97
Conformational change of erythroid alpha-spectrin at the tetramerization site upon binding beta-spectrin. Protein Sci (2007) 0.96
Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation. J Biol Chem (2010) 0.91
Slow, reversible, coupled folding and binding of the spectrin tetramerization domain. Biophys J (2012) 0.91
Characterization and expression of a heart-selective alternatively spliced variant of alpha II-spectrin, cardi+, during development in the rat. J Mol Cell Cardiol (2010) 0.81
Association studies of erythroid alpha-spectrin at the tetramerization site. Br J Haematol (2009) 0.80
A search engine to identify pathway genes from expression data on multiple organisms. BMC Syst Biol (2007) 0.79
Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs. Protein Sci (2011) 0.76
Cardiac spectrins: alternative splicing encodes functional diversity. J Mol Cell Cardiol (2010) 0.76
Spectrin tetramer formation is not required for viable development in Drosophila. J Biol Chem (2014) 0.75
Comparison of prognoses according to non-positive and positive spectrin αII expression detected immunohistochemically in epithelial ovarian carcinoma: a retrospective study. Cancer Med (2016) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
How to measure and predict the molar absorption coefficient of a protein. Protein Sci (1995) 18.71
Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. Physiol Rev (2001) 6.31
Self-association of human spectrin. A thermodynamic and kinetic study. Eur J Biochem (1978) 3.17
Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature (1982) 2.74
Erythroid spectrin, brain fodrin, and intestinal brush border proteins (TW-260/240) are related molecules containing a common calmodulin-binding subunit bound to a variant cell type-specific subunit. Proc Natl Acad Sci U S A (1982) 2.63
Self-assembly of spectrin oligomers in vitro: a basis for a dynamic cytoskeleton. J Cell Biol (1981) 2.27
Modulation of fodrin (membrane skeleton) stability by cell-cell contact in Madin-Darby canine kidney epithelial cells. J Cell Biol (1987) 2.20
The spectrin repeat: a structural platform for cytoskeletal protein assemblies. FEBS Lett (2002) 2.08
Kinetic, equilibrium, and thermodynamic analysis of macromolecular interactions with BIACORE. Methods Enzymol (2000) 2.01
Red blood cell membrane disorders. Br J Haematol (1999) 1.97
F-actin-binding and cross-linking properties of porcine brain fodrin, a spectrin-related molecule. J Biol Chem (1982) 1.73
The complete cDNA and polypeptide sequences of human erythroid alpha-spectrin. J Biol Chem (1990) 1.71
Brain spectrin. Isolation of subunits and formation of hybrids with erythrocyte spectrin subunits. J Biol Chem (1983) 1.63
Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane. J Biol Chem (2002) 1.46
Point mutation in the beta-spectrin gene associated with alpha I/74 hereditary elliptocytosis. Implications for the mechanism of spectrin dimer self-association. J Clin Invest (1990) 1.41
Location of the human red cell spectrin tetramer binding site and detection of a related "closed" hairpin loop dimer using proteolytic footprinting. J Biol Chem (1993) 1.26
Analysis of human red cell spectrin tetramer (head-to-head) assembly using complementary univalent peptides. Biochemistry (1992) 1.21
Solution structural studies on human erythrocyte alpha-spectrin tetramerization site. J Biol Chem (2003) 1.19
Spectrin redistributes to the cytosol and is phosphorylated during mitosis in cultured cells. J Cell Biol (1992) 1.11
Spectrin self-association site: characterization and study of beta-spectrin mutations associated with hereditary elliptocytosis. Biochem J (1998) 1.07
Structure of human erythrocyte spectrin. II. The sequence of the alpha-I domain. J Biol Chem (1983) 1.05
Isolation of spectrin subunits and reassociation in vitro. Analysis by fluorescence polarization. J Biol Chem (1984) 1.05
Dynamic molecular modeling of pathogenic mutations in the spectrin self-association domain. Blood (2001) 1.04
Drosophila development requires spectrin network formation. J Cell Biol (1995) 1.03
alpha beta Spectrin coiled coil association at the tetramerization site. Biochemistry (2001) 1.02
Functional characterization of recombinant human red cell alpha-spectrin polypeptides containing the tetramer binding site. J Biol Chem (1993) 1.01
A partial structural repeat forms the heterodimer self-association site of all beta-spectrins. J Biol Chem (1994) 1.00
Analysis of the self-association of human red cell spectrin. Biochemistry (1986) 0.99
Identification of a novel C-terminal variant of beta II spectrin: two isoforms of beta II spectrin have distinct intracellular locations and activities. J Cell Sci (2000) 0.98
Invariant tryptophan at a shielded site promotes folding of the conformational unit of spectrin. Proc Natl Acad Sci U S A (1994) 0.97
Thermodynamic analysis of antigen-antibody binding using biosensor measurements at different temperatures. Anal Biochem (1997) 0.92
Properties of normal and mutant polypeptide fragments from the dimer self-association sites of human red cell spectrin. Eur Biophys J (1999) 0.91
Comparison of the salt-dependent self-association of brain and erythroid spectrin. Biochemistry (1997) 0.91
Interactions of the alpha-spectrin N-terminal region with beta-spectrin. Implications for the spectrin tetramerization reaction. J Biol Chem (1999) 0.87
Properties of the C-terminal domain of 4.1 proteins. Eur J Biochem (2001) 0.86
Important region in the beta-spectrin C-terminus for spectrin tetramer formation. Eur J Haematol (2002) 0.86
Brain alpha erythroid spectrin: identification, compartmentalization, and beta spectrin associations. Brain Res (1994) 0.83
The effects of ionic strength on the self-association of human spectrin. Biochim Biophys Acta (1992) 0.78
Conformational stabilities of the structural repeats of erythroid spectrin and their functional implications. J Biol Chem (2006) 1.29
Distinct distribution of specific members of protein 4.1 gene family in the mouse nephron. Kidney Int (2003) 1.07
Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes. Proc Natl Acad Sci U S A (2006) 1.06
The transitional junction: a new functional subcellular domain at the intercalated disc. Mol Biol Cell (2006) 1.05
Ankyrin-G in skeletal muscle: tissue-specific alternative splicing contributes to the complexity of the sarcolemmal cytoskeleton. Exp Cell Res (2005) 0.99
Not just a plasma membrane protein: in cardiac muscle cells alpha-II spectrin also shows a close association with myofibrils. J Muscle Res Cell Motil (2004) 0.97
Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins. Biochemistry (2006) 0.97
Thermal stabilities of brain spectrin and the constituent repeats of subunits. Biochemistry (2006) 0.95
Lack of protein 4.1G causes altered expression and localization of the cell adhesion molecule nectin-like 4 in testis and can cause male infertility. Mol Cell Biol (2011) 0.92
Phosphorylation of a threonine unique to the short C-terminal isoform of betaII-spectrin links regulation of alpha-beta spectrin interaction to neuritogenesis. J Biol Chem (2006) 0.91
Cardiac muscle cell cytoskeletal protein 4.1: analysis of transcripts and subcellular location--relevance to membrane integrity, microstructure, and possible role in heart failure. Mamm Genome (2005) 0.90
Protein 4.1R regulates cell adhesion, spreading, migration and motility of mouse keratinocytes by modulating surface expression of beta1 integrin. J Cell Sci (2011) 0.85
Molecular evolution of ankyrin: gain of function in vertebrates by acquisition of an obscurin/titin-binding-related domain. Mol Biol Evol (2005) 0.85
Comprehensive characterization of expression patterns of protein 4.1 family members in mouse adrenal gland: implications for functions. Histochem Cell Biol (2010) 0.83
A conserved sequence in calmodulin regulated spectrin-associated protein 1 links its interaction with spectrin and calmodulin to neurite outgrowth. J Neurochem (2013) 0.83
A 130-kDa protein 4.1B regulates cell adhesion, spreading, and migration of mouse embryo fibroblasts by influencing actin cytoskeleton organization. J Biol Chem (2013) 0.81
Identification and characterization of novel spliced variants of neuregulin 4 in prostate cancer. Clin Cancer Res (2007) 0.80
Expression of human membrane skeleton protein genes for protein 4.1 and betaIISigma2-spectrin assayed by real-time RT-PCR. Cell Mol Biol Lett (2005) 0.79
Isoforms of protein 4.1 are differentially distributed in heart muscle cells: relation of 4.1R and 4.1G to components of the Ca2+ homeostasis system. Exp Cell Res (2012) 0.78
Inter-subunit interactions in erythroid and non-erythroid spectrins. Biochim Biophys Acta (2011) 0.76
Predicting post-synaptic activity in proteins with data mining. Bioinformatics (2005) 0.75
Comprehensive characterization of protein 4.1 expression in epithelium of large intestine. Histochem Cell Biol (2014) 0.75