Published in Cancer Res on July 01, 2003
Nucleation of protein fibrillation by nanoparticles. Proc Natl Acad Sci U S A (2007) 3.23
Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. Am J Respir Cell Mol Biol (2010) 2.04
Emerging roles of ATF2 and the dynamic AP1 network in cancer. Nat Rev Cancer (2010) 1.76
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling. Am J Pathol (2005) 1.60
Cellular and molecular parameters of mesothelioma. J Cell Biochem (2006) 1.57
Oxidants and signaling by mitogen-activated protein kinases in lung epithelium. Am J Respir Cell Mol Biol (2006) 1.51
Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid. PLoS Pathog (2010) 1.22
Mesothelioma: Do asbestos and carbon nanotubes pose the same health risk? Part Fibre Toxicol (2009) 1.10
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. Am J Respir Cell Mol Biol (2007) 1.05
Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. Mol Cancer (2010) 1.04
FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders. BMC Cancer (2007) 1.03
A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion. J Cell Physiol (2008) 0.98
The FOS transcription factor family differentially controls trophoblast migration and invasion. J Biol Chem (2013) 0.98
Comprehensive search for HNF-1beta-regulated genes in mouse hepatoma cells perturbed by transcription regulatory factor-targeted RNAi. Nucleic Acids Res (2004) 0.98
Actin cytoskeletal mediators of motility and invasion amplified and overexpressed in head and neck cancer. Clin Exp Metastasis (2008) 0.94
Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent. BMC Cancer (2010) 0.92
An association of a simultaneous nuclear and cytoplasmic localization of Fra-1 with breast malignancy. BMC Cancer (2006) 0.91
Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas. Mol Cancer (2007) 0.90
ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter. Biochem Biophys Res Commun (2008) 0.88
Novel functional view of the crocidolite asbestos-treated A549 human lung epithelial transcriptome reveals an intricate network of pathways with opposing functions. BMC Genomics (2008) 0.85
MicroRNA-195-5p, a new regulator of Fra-1, suppresses the migration and invasion of prostate cancer cells. J Transl Med (2015) 0.83
Targeting the MEK1 cascade in lung epithelium inhibits proliferation and fibrogenesis by asbestos. Am J Respir Cell Mol Biol (2008) 0.83
Reactive oxygen species a double-edged sword for mesothelioma. Oncotarget (2015) 0.82
FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms. Oncotarget (2016) 0.82
Estrogen-induced expression of Fos-related antigen 1 (FRA-1) regulates uterine stromal differentiation and remodeling. J Biol Chem (2012) 0.81
Quantitative analysis of tumor mitochondrial RNA using microarray. World J Gastroenterol (2005) 0.77
Discriminate gene lists derived from cDNA microarray profiles of limited samples permit distinguishing mesenchymal neoplasia ex vivo. J Cancer Res Clin Oncol (2004) 0.75
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science (2008) 16.54
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis. Proc Natl Acad Sci U S A (2006) 2.14
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases. Free Radic Biol Med (2003) 2.13
Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population. Am J Hum Genet (2004) 2.06
Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. Am J Respir Cell Mol Biol (2010) 2.04
Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol (2005) 1.82
Cellular and molecular parameters of mesothelioma. J Cell Biochem (2006) 1.57
Diseases caused by asbestos: mechanisms of injury and disease development. Int Immunopharmacol (2002) 1.57
Airway epithelial NF-kappaB activation modulates asbestos-induced inflammation and mucin production in vivo. J Immunol (2007) 1.53
Gene expression profiles predict survival and progression of pleural mesothelioma. Clin Cancer Res (2004) 1.51
Racial differences in the association between SNPs on 15q25.1, smoking behavior, and risk of non-small cell lung cancer. J Thorac Oncol (2009) 1.49
Genetic and vascular modifiers of age-sensitive cognitive skills: effects of COMT, BDNF, ApoE, and hypertension. Neuropsychology (2009) 1.48
Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth. Oncogene (2005) 1.41
Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters. Proc Natl Acad Sci U S A (2006) 1.37
Role and regulation of activator protein-1 in toxicant-induced responses of the lung. Am J Physiol Lung Cell Mol Physiol (2002) 1.33
Mesothelial cell transformation requires increased AP-1 binding activity and ERK-dependent Fra-1 expression. Cancer Res (2002) 1.33
Genes associated with prostate cancer are differentially expressed in African American and European American men. Cancer Epidemiol Biomarkers Prev (2013) 1.32
ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo. J Clin Invest (2005) 1.31
Human genetic factors in nonsyndromic cleft lip and palate: an update. Int J Pediatr Otorhinolaryngol (2007) 1.31
Volume of white matter hyperintensities in healthy adults: contribution of age, vascular risk factors, and inflammation-related genetic variants. Biochim Biophys Acta (2011) 1.29
Down-regulation of manganese-superoxide dismutase through phosphorylation of FOXO3a by Akt in explanted vascular smooth muscle cells from old rats. J Biol Chem (2006) 1.24
Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos. Oncogene (2004) 1.21
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.18
Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells. Part Fibre Toxicol (2013) 1.16
Asbestos-induced apoptosis is protein kinase C delta-dependent. Am J Respir Cell Mol Biol (2003) 1.16
Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung. FASEB J (2006) 1.15
Recent developments in orofacial cleft genetics. J Craniofac Surg (2003) 1.12
Influence of maternal-fetal histocompatibility and MHC zygosity on maternal microchimerism. J Immunol (2005) 1.10
Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice. Am J Pathol (2007) 1.10
Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies. Cytokine (2009) 1.09
Unique uptake of acid-prepared mesoporous spheres by lung epithelial and mesothelioma cells. Am J Respir Cell Mol Biol (2006) 1.09
Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model. Ann N Y Acad Sci (2010) 1.08
Activated cAMP response element binding protein is overexpressed in human mesotheliomas and inhibits apoptosis. Am J Pathol (2009) 1.07
Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. J Vasc Surg (2005) 1.07
Alterations in gene expression in human mesothelial cells correlate with mineral pathogenicity. Am J Respir Cell Mol Biol (2008) 1.06
HGF mediates cell proliferation of human mesothelioma cells through a PI3K/MEK5/Fra-1 pathway. Am J Respir Cell Mol Biol (2007) 1.05
Assessing nanotoxicity in cells in vitro. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.05
Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production. J Immunol (2009) 1.04
Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin. Mol Cancer (2010) 1.04
Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women. Cancer Epidemiol Biomarkers Prev (2009) 1.02
Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1). J Toxicol Environ Health A (2010) 1.02
Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy. Int J Cancer (2010) 1.02
Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis. Am J Pathol (2011) 1.01
Activation of NF-kappaB-dependent gene expression by silica in lungs of luciferase reporter mice. Am J Physiol Lung Cell Mol Physiol (2002) 1.01
Study of four genes belonging to the folate pathway: transcobalamin 2 is involved in the onset of non-syndromic cleft lip with or without cleft palate. Hum Mutat (2006) 1.01
ERK2 is essential for the growth of human epithelioid malignant mesotheliomas. Int J Cancer (2011) 1.00
Silica induces NLRP3 inflammasome activation in human lung epithelial cells. Part Fibre Toxicol (2013) 1.00
Human mesothelioma cells exhibit tumor cell-specific differences in phosphatidylinositol 3-kinase/AKT activity that predict the efficacy of Onconase. Mol Cancer Ther (2005) 1.00
Asbestos-induced lung inflammation and epithelial cell proliferation are altered in myeloperoxidase-null mice. Cancer Res (2005) 1.00
The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos. Cancer Res (2004) 0.98
Effects of age, genes, and pulse pressure on executive functions in healthy adults. Neurobiol Aging (2009) 0.98
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells. Part Fibre Toxicol (2012) 0.98
Medpor regulates osteoblast's microRNAs. Biomed Mater Eng (2008) 0.96
Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis. Am J Pathol (2003) 0.96
Differences in osteoblast miRNA induced by cell binding domain of collagen and silicate-based synthetic bone. J Biomed Sci (2007) 0.95
A mutant epidermal growth factor receptor targeted to lung epithelium inhibits asbestos-induced proliferation and proto-oncogene expression. Cancer Res (2002) 0.95
Identification of differentially expressed genes in human salivary gland tumors by DNA microarrays. Mol Cancer Ther (2002) 0.95
Intronic non-CG DNA hydroxymethylation and alternative mRNA splicing in honey bees. BMC Genomics (2013) 0.94
Linkage disequilibrium between GABRB3 gene and nonsyndromic familial cleft lip with or without cleft palate. Hum Genet (2001) 0.94
Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation. Part Fibre Toxicol (2014) 0.93
Increased localization and substrate activation of protein kinase C delta in lung epithelial cells following exposure to asbestos. Am J Pathol (2002) 0.93
A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant Mesothelioma. Genes Cancer (2010) 0.93
Comparison between genetic portraits of osteoblasts derived from primary cultures and osteoblasts obtained from human pulpar stem cells. J Craniofac Surg (2008) 0.92
The gamma-glutamylcysteine synthetase and glutathione regulate asbestos-induced expression of activator protein-1 family members and activity. Cancer Res (2004) 0.92
Gd-labeled microparticles in MRI: in vivo imaging of microparticles after intraperitoneal injection. Small (2010) 0.92
A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos. Am J Pathol (2008) 0.91
Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2. Am J Physiol Lung Cell Mol Physiol (2007) 0.91
Genes causing clefting syndromes as candidates for non-syndromic cleft lip with or without cleft palate: a family-based association study. Eur J Oral Sci (2008) 0.91
Mechanisms of oxidative stress and alterations in gene expression by Libby six-mix in human mesothelial cells. Part Fibre Toxicol (2010) 0.90
Genetic effects of anorganic bovine bone (Bio-Oss) on osteoblast-like MG63 cells. Arch Oral Biol (2005) 0.90
Fra-1 governs cell migration via modulation of CD44 expression in human mesotheliomas. Mol Cancer (2007) 0.90
Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells. J Cell Physiol (2006) 0.90
Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women. J Cancer Epidemiol (2010) 0.90
PerioGlas regulates osteoblast RNA interfering. J Prosthodont (2008) 0.89
Low prevalence of human papillomavirus in squamous-cell carcinoma limited to oral cavity proper. Mod Pathol (2008) 0.89
Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells. Apoptosis (2008) 0.89
Extracellular signal-regulated kinase 5: a potential therapeutic target for malignant mesotheliomas. Clin Cancer Res (2013) 0.89
Association of maternal histocompatibility at class II HLA loci with maternal microchimerism in the fetus. Pediatr Res (2004) 0.89
Association of kallikrein gene polymorphisms with intracranial aneurysms. Stroke (2007) 0.88
Decreased asbestos-induced lung inflammation and fibrosis after radiation and bone marrow transplant. Am J Respir Cell Mol Biol (2007) 0.88
Expression profiles of craniosynostosis-derived fibroblasts. Mol Med (2002) 0.88
Investigation of the W185X nonsense mutation of PVRL1 gene in Italian nonsyndromic cleft lip and palate patients. Am J Med Genet A (2004) 0.87
Expression profiling of ameloblastic carcinoma. J Craniofac Surg (2004) 0.87
Peptide-15 changes miRNA expression in osteoblast-like cells. Implant Dent (2008) 0.87
Volume of the hippocampal subfields in healthy adults: differential associations with age and a pro-inflammatory genetic variant. Brain Struct Funct (2014) 0.86
Integration of expression profiles and genetic mapping data to identify candidate genes in intracranial aneurysm. Physiol Genomics (2007) 0.86
Functional polymorphisms to modulate luminal lipid exposure and risk of colorectal cancer. Cancer Epidemiol (2010) 0.86
Oxidant-mediated cAMP response element binding protein activation: calcium regulation and role in apoptosis of lung epithelial cells. Am J Respir Cell Mol Biol (2005) 0.86
Comparison between titanium and anatase miRNAs regulation. Nanomedicine (2007) 0.86