Published in Lancet on June 28, 2003
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Clonal association between Streptococcus pneumoniae serotype 23A, circulating within the United States, and an internationally dispersed clone of serotype 23F. J Clin Microbiol (2005) 1.06
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Antibody levels after regular childhood vaccinations in the immunological screening of children with recurrent otitis media. J Clin Immunol (2004) 0.86
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Caseinolytic protease: a protein vaccine which could elicit serotype-independent protection against invasive pneumococcal infection. Clin Exp Immunol (2009) 0.82
Pneumococcal conjugate vaccination in Canadian infants and children younger than five years of age: Recommendations and expected benefits. Can J Infect Dis Med Microbiol (2006) 0.82
Association between early bacterial carriage and otitis media in Aboriginal and non-Aboriginal children in a semi-arid area of Western Australia: a cohort study. BMC Infect Dis (2012) 0.81
Respiratory microbiota dynamics following Streptococcus pneumoniae acquisition in young and elderly mice. Infect Immun (2014) 0.81
Mucosal immunology of vaccines against pathogenic nasopharyngeal bacteria. J Clin Pathol (2004) 0.80
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Bacterial and Respiratory Viral Interactions in the Etiology of Acute Otitis Media in HIV-infected and HIV-uninfected South African Children. Pediatr Infect Dis J (2015) 0.79
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Resistance to complement-mediated killing and IgM binding to non-typeable Haemophilus influenzae is not altered when ascending from the nasopharynx to the middle ears in children with otitis media. Med Microbiol Immunol (2013) 0.79
Adenovirus species C is associated with chronic suppurative lung diseases in children. Clin Infect Dis (2014) 0.79
Multiple Streptococcus pneumoniae serotypes in aural discharge samples from children with acute otitis media with spontaneous otorrhea. J Clin Microbiol (2013) 0.77
Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae. Infect Genet Evol (2007) 0.77
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Pneumococcal conjugate vaccine for acute otitis media--yes or no? Lancet (2003) 0.77
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Nasopharyngeal colonization of Gambian infants by Staphylococcus aureus and Streptococcus pneumoniae before the introduction of pneumococcal conjugate vaccines. New Microbes New Infect (2015) 0.75
Effect of conjugate pneumococcal vaccine on recurrent acute otitis media. Lancet (2003) 0.75
Diet as a risk factor for pneumococcal carriage and otitis media: a cross-sectional study among children in day care centers. PLoS One (2014) 0.75
Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes. Vaccine (2015) 0.75
Streptococcus pneumoniae oropharyngeal colonization in school-age children and adolescents with type 1 diabetes mellitus: Impact of the heptavalent pneumococcal conjugate vaccine. Hum Vaccin Immunother (2015) 0.75
Utilizing Pharmacy Records to Assess Antibiotic Prescribing Patterns on the Incidence of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infections in Children. J Pediatr Pharmacol Ther (2007) 0.75
Mycoplasma pneumoniae and Streptococcus pneumoniae caused different microbial structure and correlation network in lung microbiota. J Thorac Dis (2016) 0.75
Simulating recurrent event data with hazard functions defined on a total time scale. BMC Med Res Methodol (2015) 0.75
Pneumococcal vaccination does not affect the genetic diversity of Moraxella catarrhalis isolates in children. Eur J Clin Microbiol Infect Dis (2004) 0.75
Can vaccination against pneumococci prevent otitis media with effusion? Eur Arch Otorhinolaryngol (2012) 0.75
Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N Engl J Med (2002) 6.25
Interleukin-17A mediates acquired immunity to pneumococcal colonization. PLoS Pathog (2008) 4.05
Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells. Clin Diagn Lab Immunol (2003) 3.70
Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients. J Infect Dis (2003) 2.91
Pneumococcal capsular polysaccharide structure predicts serotype prevalence. PLoS Pathog (2009) 2.69
Serum lipids and disease severity in children with severe meningococcal sepsis. Crit Care Med (2005) 2.46
CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J Immunol (2004) 2.45
Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease. Nat Genet (2010) 2.32
Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis. Pediatr Pulmonol (2011) 2.32
Variability and diversity of nasopharyngeal microbiota in children: a metagenomic analysis. PLoS One (2011) 2.29
Antibiotic prophylaxis for urinary tract infections in children with spina bifida on intermittent catheterization. J Urol (2011) 2.18
Preliminary core sets of measures for disease activity and damage assessment in juvenile systemic lupus erythematosus and juvenile dermatomyositis. Rheumatology (Oxford) (2003) 2.18
Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies. J Immunol Methods (2005) 2.09
Skeletal effects and functional outcome with olpadronate in children with osteogenesis imperfecta: a 2-year randomised placebo-controlled study. Lancet (2004) 1.95
Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study. Ann Rheum Dis (2006) 1.95
Efficacy of highly active antiretroviral therapy in HIV-1 infected children. Lancet Infect Dis (2002) 1.94
Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis. Lancet (2005) 1.93
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The impact of breastfeeding on nasopharyngeal microbial communities in infants. Am J Respir Crit Care Med (2014) 1.78
Deep sequencing analyses of low density microbial communities: working at the boundary of accurate microbiota detection. PLoS One (2012) 1.76
Viral and bacterial interactions in the upper respiratory tract. PLoS Pathog (2013) 1.74
A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice. Blood (2003) 1.74
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study. Crit Care Med (2003) 1.68
CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. J Bacteriol (2007) 1.64
Associations between pathogens in the upper respiratory tract of young children: interplay between viruses and bacteria. PLoS One (2012) 1.63
Juvenile polyarteritis: results of a multicenter survey of 110 children. J Pediatr (2004) 1.57
Hospitalization for respiratory syncytial virus infection in young children: development of a clinical prediction rule. Pediatr Infect Dis J (2006) 1.55
Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatment. Ann Rheum Dis (2007) 1.55
Platelet count, previous infection and FCGR2B genotype predict development of chronic disease in newly diagnosed idiopathic thrombocytopenia in childhood: results of a prospective study. Br J Haematol (2004) 1.53
Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children. Am J Respir Crit Care Med (2014) 1.49
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Mirrored symptoms in mother and child with chronic fatigue syndrome. Pediatrics (2006) 1.42
Chlamydia trachomatis infection during pregnancy associated with preterm delivery: a population-based prospective cohort study. Eur J Epidemiol (2011) 1.42
Paediatric conferences: only a profit making enterprise? Acta Paediatr (2012) 1.41
Decreased expression of serum and microvascular vascular endothelial growth factor receptor-2 in meningococcal sepsis*. Pediatr Crit Care Med (2013) 1.38
Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media. Pediatrics (2007) 1.37
Variant chronic infantile neurologic, cutaneous, articular syndrome due to a mutation within the leucine-rich repeat domain of CIAS1. Arthritis Rheum (2004) 1.36
Anakinra in mutation-negative NOMID/CINCA syndrome: comment on the articles by Hawkins et al and Hoffman and Patel. Arthritis Rheum (2004) 1.34
Comparative genomics of prevaccination and modern Bordetella pertussis strains. BMC Genomics (2010) 1.33
Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome. Arthritis Rheum (2002) 1.30
High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: development and validation of a methotrexate intolerance severity score. Arthritis Rheum (2011) 1.30
Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology (Oxford) (2009) 1.26
Effect of seven-valent pneumococcal conjugate vaccine on Staphylococcus aureus colonisation in a randomised controlled trial. PLoS One (2011) 1.25
Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow. Blood (2002) 1.23
Swaddling: a systematic review. Pediatrics (2007) 1.22
Pneumococcal conjugate vaccination and nasopharyngeal acquisition of pneumococcal serotype 19A strains. JAMA (2010) 1.21
Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study. Hum Mutat (2012) 1.19
Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis. Arthritis Rheum (2003) 1.17
Effect of butyrate enemas on inflammation and antioxidant status in the colonic mucosa of patients with ulcerative colitis in remission. Clin Nutr (2010) 1.16
Clinical and molecular epidemiologic characteristics of coagulase-negative staphylococcal bloodstream infections in intensive care neonates. Pediatr Infect Dis J (2007) 1.16
CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity. Crit Care (2006) 1.12
The role of human innate immune factors in nasal colonization by Staphylococcus aureus. Microbes Infect (2007) 1.11
Central role of complement in passive protection by human IgG1 and IgG2 anti-pneumococcal antibodies in mice. J Immunol (2003) 1.10
Meropenem pharmacokinetics in the newborn. Antimicrob Agents Chemother (2009) 1.10
Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations. Arthritis Rheum (2004) 1.09
Temperature dependence of mutant mevalonate kinase activity as a pathogenic factor in hyper-IgD and periodic fever syndrome. Hum Mol Genet (2002) 1.09
Serum antipneumococcal antibodies and pneumococcal colonization in adults with chronic obstructive pulmonary disease. J Infect Dis (2007) 1.09
Site-specific contributions of glutamine-dependent regulator GlnR and GlnR-regulated genes to virulence of Streptococcus pneumoniae. Infect Immun (2008) 1.09
Multiplex PCR reveals a high rate of nasopharyngeal pneumococcal 7-valent conjugate vaccine serotypes co-colonizing indigenous Warao children in Venezuela. J Med Microbiol (2009) 1.09
Seven-valent pneumococcal conjugate vaccine and nasopharyngeal microbiota in healthy children. Emerg Infect Dis (2014) 1.08
Coagulase-negative staphylococcal skin carriage among neonatal intensive care unit personnel: from population to infection. J Clin Microbiol (2010) 1.08
Results of 2 years of treatment with protease-inhibitor--containing antiretroviral therapy in dutch children infected with human immunodeficiency virus type 1. Clin Infect Dis (2002) 1.07
Factors associated with pneumococcal carriage in healthy Dutch infants: the generation R study. J Pediatr (2008) 1.07
Systemic JIA: new developments in the understanding of the pathophysiology and therapy. Best Pract Res Clin Rheumatol (2009) 1.05
Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: results of a prospective cohort study. Arthritis Rheumatol (2014) 1.04
Chlamydia trachomatis as a cause of neonatal conjunctivitis in Dutch infants. Pediatrics (2008) 1.03
Detection of lipoatrophy in human immunodeficiency virus-1-infected children treated with highly active antiretroviral therapy. Pediatr Infect Dis J (2006) 1.02
Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1. Blood (2004) 1.01
Composition of precursor B-cell compartment in bone marrow from patients with X-linked agammaglobulinemia compared with healthy children. Pediatr Res (2002) 1.01
Plasma concentrations of the HIV-protease inhibitor lopinavir are suboptimal in children aged 2 years and below. Antivir Ther (2007) 1.01
Improved survival of children with sepsis and purpura: effects of age, gender, and era. Crit Care (2007) 1.00
Superiority of trans-oral over trans-nasal sampling in detecting Streptococcus pneumoniae colonization in adults. PLoS One (2013) 0.99
Overt and occult rheumatic diseases: the child with chronic fever. Best Pract Res Clin Rheumatol (2002) 0.99
Nasopharyngeal co-colonization with Staphylococcus aureus and Streptococcus pneumoniae in children is bacterial genotype independent. Microbiology (2007) 0.98
Radiologic features in juvenile idiopathic arthritis: a first step in the development of a standardized assessment method. Arthritis Rheum (2003) 0.97
Human immunodeficiency virus and tuberculosis coinfection in children: challenges in diagnosis and treatment. Pediatr Infect Dis J (2010) 0.97
Does pneumococcal conjugate vaccine influence Staphylococcus aureus carriage in children? Clin Infect Dis (2008) 0.96
Nasopharyngeal pneumococcal carriage after combined pneumococcal conjugate and polysaccharide vaccination in children with a history of recurrent acute otitis media. Clin Infect Dis (2004) 0.95
Pharmacokinetics of a once-daily regimen of lopinavir/ritonavir in HIV-1-infected children. Antivir Ther (2006) 0.95
Use of MMP-8 and MMP-9 to assess disease severity in children with viral lower respiratory tract infections. J Med Virol (2012) 0.95
Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis. Ann Rheum Dis (2007) 0.94
Chlamydia trachomatis and placental inflammation in early preterm delivery. Eur J Epidemiol (2011) 0.94
Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells in patients with juvenile dermatomyositis. Arthritis Rheum (2008) 0.94
Genetic relatedness between pneumococcal populations originating from the nasopharynx, adenoid, and tympanic cavity of children with otitis media. J Clin Microbiol (2005) 0.94
Pneumococcal carriage among indigenous Warao children in Venezuela: serotypes, susceptibility patterns, and molecular epidemiology. Clin Infect Dis (2007) 0.93
Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum (2009) 0.92
The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children. Br J Nutr (2009) 0.92
CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype. J Immunol (2010) 0.92
Case report: severe central nervous system involvement in juvenile dermatomyositis. J Rheumatol (2003) 0.92