Published in EMBO J on July 15, 2003
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix. EMBO J (2004) 1.27
Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proc Natl Acad Sci U S A (2006) 1.08
Targeting of acetylcholinesterase in neurons in vivo: a dual processing function for the proline-rich membrane anchor subunit and the attachment domain on the catalytic subunit. J Neurosci (2009) 1.04
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. J Biol Chem (2010) 0.99
Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation. Front Mol Neurosci (2011) 0.86
Pro-apoptotic protein-protein interactions of the extended N-AChE terminus. J Neural Transm (Vienna) (2009) 0.80
Erv26p-dependent export of alkaline phosphatase from the ER requires lumenal domain recognition. Traffic (2009) 0.80
Radiometric assay of ghrelin hydrolase activity and (3)H-ghrelin distribution into mouse tissues. Biochem Pharmacol (2015) 0.79
The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain. J Biol Chem (2010) 0.79
Rescue and Stabilization of Acetylcholinesterase in Skeletal Muscle by N-terminal Peptides Derived from the Noncatalytic Subunits. J Biol Chem (2015) 0.75
Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol (1987) 66.52
A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol (1961) 45.34
A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES. J Histochem Cytochem (1964) 10.70
Quality control in the endoplasmic reticulum. Nat Rev Mol Cell Biol (2003) 9.85
Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes. J Biol Chem (1986) 6.03
Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum. J Biol Chem (1988) 5.18
Protein degradation in the endoplasmic reticulum. Cell (1990) 4.04
Molecular and cellular biology of cholinesterases. Prog Neurobiol (1993) 3.01
ER protein quality control and proteasome-mediated protein degradation. Semin Cell Dev Biol (1999) 2.55
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine. Cell (1990) 2.12
PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron (2002) 1.66
Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I. J Biol Chem (2000) 1.44
Quaternary associations of acetylcholinesterase. II. The polyproline attachment domain of the collagen tail. J Biol Chem (1997) 1.42
The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals (2002) 1.39
The KDEL receptor mediates a retrieval mechanism that contributes to quality control at the endoplasmic reticulum. EMBO J (2001) 1.35
Genetic analysis of collagen Q: roles in acetylcholinesterase and butyrylcholinesterase assembly and in synaptic structure and function. J Cell Biol (1999) 1.33
Proteasomal degradation and N-terminal protease resistance of the codon 145 mutant prion protein. J Biol Chem (1999) 1.30
H and T subunits of acetylcholinesterase from Torpedo, expressed in COS cells, generate all types of globular forms. J Cell Biol (1992) 1.24
Glycoprotein quality control in the endoplasmic reticulum. Mannose trimming by endoplasmic reticulum mannosidase I times the proteasomal degradation of unassembled immunoglobulin subunits. J Biol Chem (2001) 1.16
Quaternary associations of acetylcholinesterase. I. Oligomeric associations of T subunits with and without the amino-terminal domain of the collagen tail. J Biol Chem (1997) 1.15
Tetramerization domain of human butyrylcholinesterase is at the C-terminus. Biochem J (1997) 1.12
The effect of elimination of intersubunit disulfide bonds on the activity, assembly, and secretion of recombinant human acetylcholinesterase. Expression of acetylcholinesterase Cys-580----Ala mutant. J Biol Chem (1991) 1.10
Cloning and expression of a rat acetylcholinesterase subunit: generation of multiple molecular forms and complementarity with a Torpedo collagenic subunit. J Neurochem (1993) 1.09
Acetylcholinesterase H and T dimers are associated through the same contact. Mutations at this interface interfere with the C-terminal T peptide, inducing degradation rather than secretion. J Biol Chem (2001) 1.08
An immunological study of rat acetylcholinesterase: comparison with acetylcholinesterases from other vertebrates. J Neurochem (1984) 1.01
The solubilization of tetrameric alkaline phosphatase from human liver and its conversion into various forms by phosphatidylinositol phospholipase C or proteolysis. J Biol Chem (1988) 0.97
Interactions underlying subunit association in cholinesterases. Protein Eng (1997) 0.88
Cloning, expression, and properties of a nonneuronal secreted acetylcholinesterase from the parasitic nematode Nippostrongylus brasiliensis. J Biol Chem (1999) 0.85
Tetrameric (G4) acetylcholinesterase: structure, localization, and physiological regulation. J Neurochem (1996) 0.82
PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron (2002) 1.66
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix. EMBO J (2004) 1.27
Targeting acetylcholinesterase to membrane rafts: a function mediated by the proline-rich membrane anchor (PRiMA) in neurons. J Biol Chem (2010) 0.99
Protein CutA undergoes an unusual transfer into the secretory pathway and affects the folding, oligomerization, and secretion of acetylcholinesterase. J Biol Chem (2008) 0.95
The C-terminal peptides of acetylcholinesterase: cellular trafficking, oligomerization and functional anchoring. Chem Biol Interact (2005) 0.95
The readthrough variant of acetylcholinesterase remains very minor after heat shock, organophosphate inhibition and stress, in cell culture and in vivo. J Neurochem (2005) 0.90
Transcriptional regulation of acetylcholinesterase-associated collagen ColQ: differential expression in fast and slow twitch muscle fibers is driven by distinct promoters. J Biol Chem (2004) 0.90
Assembly of acetylcholinesterase tetramers by peptidic motifs from the proline-rich membrane anchor, PRiMA: competition between degradation and secretion pathways of heteromeric complexes. J Biol Chem (2006) 0.88
Elements of the C-terminal t peptide of acetylcholinesterase that determine amphiphilicity, homomeric and heteromeric associations, secretion and degradation. Eur J Biochem (2004) 0.86
The C-terminal T peptide of cholinesterases: structure, interactions, and influence on protein folding and secretion. J Mol Neurosci (2006) 0.86
Trimerization domain of the collagen tail of acetylcholinesterase. Neurochem Res (2003) 0.86
The C-terminal t peptide of acetylcholinesterase forms an alpha helix that supports homomeric and heteromeric interactions. Eur J Biochem (2004) 0.86
Old and new questions about cholinesterases. Chem Biol Interact (2008) 0.85
Altered GPI modification of insect AChE improves tolerance to organophosphate insecticides. Insect Biochem Mol Biol (2010) 0.85
Non-antisense cellular responses to oligonucleotides. FEBS Lett (2002) 0.84
Determinants of the t peptide involved in folding, degradation, and secretion of acetylcholinesterase. J Biol Chem (2004) 0.83
Expression of PRiMA in the mouse brain: membrane anchoring and accumulation of 'tailed' acetylcholinesterase. Eur J Neurosci (2003) 0.83
Acetylcholinesterase associates differently with its anchoring proteins ColQ and PRiMA. J Biol Chem (2008) 0.82
Transcriptional regulation of gene expression by the coding sequence: An attempt to enhance expression of human AChE. Biotechnol Bioeng (2002) 0.79
Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase. Chembiochem (2003) 0.79
The PRiMA-linked cholinesterase tetramers are assembled from homodimers: hybrid molecules composed of acetylcholinesterase and butyrylcholinesterase dimers are up-regulated during development of chicken brain. J Biol Chem (2010) 0.79
Unusual transfer of CutA into the secretory pathway, evidenced by fusion proteins with acetylcholinesterase. FEBS J (2009) 0.77
Readthrough acetylcholinesterase expression remains minor after stress or exposure to inhibitors. J Mol Neurosci (2006) 0.75
Regulation of PRiMA: membrane anchor of acetylcholinesterase (AChE) in neuron and muscle. Chem Biol Interact (2005) 0.75