Justin A Caravella

Author PubWeight™ 11.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway. Cell 2003 1.44
2 The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily. Nucleic Acids Res 2003 1.20
3 Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene. Bioorg Med Chem Lett 2010 0.99
4 Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J Med Chem 2008 0.96
5 Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure. J Med Chem 2005 0.91
6 Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064. Bioorg Med Chem Lett 2008 0.89
7 Dynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain. J Biol Chem 2012 0.87
8 FXR agonist activity of conformationally constrained analogs of GW 4064. Bioorg Med Chem Lett 2009 0.83
9 Conformationally constrained farnesoid X receptor (FXR) agonists: alternative replacements of the stilbene. Bioorg Med Chem Lett 2011 0.80
10 Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064. Bioorg Med Chem Lett 2009 0.80
11 Structure-Guided Design of Antibodies. Curr Comput Aided Drug Des 2010 0.77
12 Highly covarying residues have a functional role in antibody constant domains. Proteins 2013 0.77
13 Metric to distinguish closely related domain families using sequence information. J Mol Biol 2012 0.75