Published in Arterioscler Thromb Vasc Biol on July 01, 2003
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2. Arterioscler Thromb Vasc Biol (2003) 2.15
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem (2002) 4.28
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. J Exp Med (2012) 3.63
Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. J Exp Med (2007) 3.35
Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood (2004) 3.31
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis. Blood (2004) 2.41
Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J Clin Invest (2008) 2.39
Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J Exp Med (2006) 2.39
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways. J Immunol (2007) 2.32
Microparticles in hemostasis and thrombosis. Circ Res (2011) 2.26
Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood (2003) 2.20
Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood (2004) 2.16
Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice. Blood (2010) 2.10
The thrombomodulin-protein C system is essential for the maintenance of pregnancy. Nat Med (2003) 1.98
Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy. Circulation (2007) 1.97
Role of tissue factor in cancer. J Clin Oncol (2009) 1.91
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78. Arterioscler Thromb Vasc Biol (2005) 1.82
Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J Immunol (2008) 1.74
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice. Arterioscler Thromb Vasc Biol (2004) 1.65
Chlamydia pneumoniae induces tissue factor expression in mouse macrophages via activation of Egr-1 and the MEK-ERK1/2 pathway. Circ Res (2003) 1.59
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. Circ Res (2008) 1.55
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease. Blood (2014) 1.53
Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. J Clin Invest (2012) 1.51
Protease-activated receptor-2 regulates the innate immune response to viral infection in a coxsackievirus B3-induced myocarditis. J Am Coll Cardiol (2013) 1.50
Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury. Blood (2007) 1.49
PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. Blood (2012) 1.48
Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood (2011) 1.48
Critical review of mouse models of venous thrombosis. Arterioscler Thromb Vasc Biol (2012) 1.46
Increased microparticle tissue factor activity in cancer patients with Venous Thromboembolism. Thromb Res (2009) 1.43
Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. J Immunol (2005) 1.36
Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation. Blood (2012) 1.34
Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. Blood (2008) 1.32
Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: lessons from low tissue factor mice. Thromb Haemost (2004) 1.28
A balance between tissue factor and tissue factor pathway inhibitor is required for embryonic development and hemostasis in adult mice. Blood (2004) 1.26
Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest (2013) 1.24
Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice. Hepatology (2007) 1.23
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest (2008) 1.23
Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. Cancer Res (2009) 1.22
Tissue factor in hemostasis and thrombosis. Semin Thromb Hemost (2006) 1.21
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer. Blood (2012) 1.20
Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis. Cancer Res (2008) 1.19
Tumor-derived tissue factor-positive microparticles and venous thrombosis in cancer patients. Blood (2013) 1.19
Factor XIII activity mediates red blood cell retention in venous thrombi. J Clin Invest (2014) 1.18
Tissue factor deficiency and PAR-1 deficiency are protective against renal ischemia reperfusion injury. Blood (2006) 1.18
Tissue factor and its measurement in whole blood, plasma, and microparticles. Semin Thromb Hemost (2010) 1.17
Oncogenes, trousseau syndrome, and cancer-related changes in the coagulome of mice and humans. Cancer Res (2006) 1.16
Tissue factor and thrombosis: The clot starts here. Thromb Haemost (2010) 1.16
COX-2 suppresses tissue factor expression via endocannabinoid-directed PPARdelta activation. J Exp Med (2007) 1.16
Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res (2006) 1.13
Tissue factor, coagulation proteases, and protease-activated receptors in endotoxemia and sepsis. Crit Care Med (2004) 1.12
Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model. Blood (2003) 1.11
Induction of tissue factor expression in human endothelial cells by CD40 ligand is mediated via activator protein 1, nuclear factor kappa B, and Egr-1. J Biol Chem (2002) 1.11
PAR-1 contributes to the innate immune response during viral infection. J Clin Invest (2013) 1.09
Cellular sources of tissue factor in endotoxemia and sepsis. Thromb Res (2010) 1.09
Role of tissue factor in venous thrombosis. Annu Rev Physiol (2011) 1.09
Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway. J Biol Chem (2008) 1.08
Contribution of host-derived tissue factor to tumor neovascularization. Arterioscler Thromb Vasc Biol (2008) 1.08
Insulin activation of the phosphatidylinositol 3-kinase/protein kinase B (Akt) pathway reduces lipopolysaccharide-induced inflammation in mice. J Pharmacol Exp Ther (2008) 1.07
Tissue factor-dependent coagulation contributes to alpha-naphthylisothiocyanate-induced cholestatic liver injury in mice. Am J Physiol Gastrointest Liver Physiol (2009) 1.07
Tissue Factor and Atherothrombosis. J Atheroscler Thromb (2015) 1.05
Tissue factor-activated coagulation cascade in the tumor microenvironment is critical for tumor progression and an effective target for therapy. Cancer Res (2011) 1.04
Coagulation activation and microparticle-associated coagulant activity in cancer patients. An exploratory prospective study. Thromb Haemost (2012) 1.04
Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients. Thromb Res (2008) 1.04
Detection of endogenous tissue factor levels in plasma using the calibrated automated thrombogram assay. Thromb Res (2009) 1.04
TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. Mol Immunol (2008) 1.02
Role of tissue factor in a mouse model of thrombotic microangiopathy induced by antiphospholipid antibodies. Blood (2009) 1.01
Protease-activated receptor 2 deficiency reduces cardiac ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol (2010) 1.00
RASA3 is a critical inhibitor of RAP1-dependent platelet activation. J Clin Invest (2015) 0.99
Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress. Thorax (2012) 0.99
Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression. Mol Immunol (2009) 0.99
Alternatively spliced tissue factor - one cut too many? Thromb Haemost (2007) 0.98
Protease-activated receptors and myocardial infarction. IUBMB Life (2011) 0.98
β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells. Circulation (2012) 0.97
Circulating microparticle tissue factor, thromboembolism and survival in pancreaticobiliary cancers. Thromb Res (2013) 0.97
Potent inhibition of thrombin with a monoclonal antibody against tissue factor (Sunol-cH36): results of the PROXIMATE-TIMI 27 trial. Eur Heart J (2005) 0.97
Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet. Am J Pathol (2011) 0.96
Lipopolysaccharide inhibition of glucose production through the Toll-like receptor-4, myeloid differentiation factor 88, and nuclear factor kappa b pathway. Hepatology (2009) 0.96
The role of tumor-and host-related tissue factor pools in oncogene-driven tumor progression. Thromb Res (2007) 0.95
NF-kappaB transcription factor p50 critically regulates tissue factor in deep vein thrombosis. J Biol Chem (2008) 0.95
Protease-activated receptors mediate crosstalk between coagulation and fibrinolysis. Blood (2010) 0.95
Tissue factor and thrombin mediate myocardial ischemia-reperfusion injury. Ann Thorac Surg (2003) 0.94
Multiple roles of the coagulation protease cascade during virus infection. Blood (2014) 0.94
On the trail of microparticles. Circ Res (2009) 0.93
Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease. Blood (2012) 0.93
Eculizumab therapy results in rapid and sustained decreases in markers of thrombin generation and inflammation in patients with PNH independent of its effects on hemolysis and microparticle formation. Thromb Res (2012) 0.93
Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations. Proc Natl Acad Sci U S A (2014) 0.91
Coagulation, protease-activated receptors, and viral myocarditis. J Cardiovasc Transl Res (2013) 0.91
Anthracycline treatment of the human monocytic leukemia cell line THP-1 increases phosphatidylserine exposure and tissue factor activity. Thromb Res (2011) 0.91
Hepatocyte tissue factor activates the coagulation cascade in mice. Blood (2013) 0.90
Microparticles and cancer. Pathophysiol Haemost Thromb (2009) 0.89
Microvesicles as risk markers for venous thrombosis. Expert Rev Hematol (2013) 0.89
Sources of tissue factor that contribute to thrombosis after rupture of an atherosclerotic plaque. Thromb Res (2012) 0.88
Role of coagulation factors in cerebral venous sinus and cerebral microvascular thrombosis. Neurosurgery (2010) 0.88
Venous thromboembolism: a need for more public awareness and research into mechanisms. Arterioscler Thromb Vasc Biol (2008) 0.87
Tissue factor in health and disease. Front Biosci (Elite Ed) (2012) 0.87
Atherosclerosis in mice is not affected by a reduction in tissue factor expression. Arterioscler Thromb Vasc Biol (2005) 0.87
Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury. Toxicol Sci (2010) 0.87
Role of tissue factor in atherothrombosis. Curr Atheroscler Rep (2012) 0.86
A novel class of antioxidants inhibit LPS induction of tissue factor by selective inhibition of the activation of ASK1 and MAP kinases. Arterioscler Thromb Vasc Biol (2007) 0.86